... patients (including 82 lung cancer) SDS The single measure of symptom distress was a significant predictor of survival in lung cancer Ringdal et al [16] 1996 253 heterogeneous sample of cancer patients ... in interpreting the findings from studies of the relationship between quality of life data and survival duration Quality of life data might be markers of the socio-economic status of cancer patients ... survival in a heterogeneous sample of cancer patients Br J Cancer 1996, 73:1594-1599 Tamburini M, Brunelli C, Rosso S, Ventafridda V: Prognostic value of quality of life scores in terminal cancer patients...
Ngày tải lên: 18/06/2014, 19:20
... reporting on the results of the "epidemiological" part of the study, including a description of patients' characteristics in terms of baseline socio-demographic and clinical variables, pattern of ... average pain score of ≥ points (pain intensity difference, PID, >/= 2) at week (day 28 from inclusion) over baseline As to the assessment of the quality of analgesic care, the adequacy of pain management ... example, the choice of morphine in eligible patients) , eventually the comparison of outcomes (for example, pian intensity) by matching or stratifing patients according to the value of the propensity...
Ngày tải lên: 20/06/2014, 15:20
Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... guided internal jugular vein catheterization Patients with neutropenia 254 of 1660 Patients with low platelet count 116 of 1660 N Patients % of patients N neutrophil/mm3 N Patients % of patients ... insertion in patients with cancer Background Central venous access is essential in patients with cancer, and the need for intravenous access devices for the administration of cancer therapy has increased ... determines an increase of the diameter of the veins Under ultrasoundguide in real time, a 16-gauge needle is introduced into the last portion of internal jugular vein This vein was reached through...
Ngày tải lên: 09/08/2014, 03:22
báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... unfractionated heparin *For definitions of major bleeding see original studies † Included non -cancer patients for routine thromboprophylaxis in medical cancer patients [1,16-19] However, in the Fundamental ... therefore, LMWHs offer considerable advantages over warfarin in cancer patients in terms of practicality of use as well as in efficacy Cost comparisons The costs involved in managing VTE in general ... development, which offer potential benefits over existing therapies in cancer patients [108,109] For instance, as cancer patients are at an increased risk both of VTE and bleeding [30,31], cancer patients...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo khoa học: "Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study" pot
... physicians in discussions of prognosis and in clinical decision making to improve allocation of resources in intensive care [12] Stratification of patients for clinical research and assessment of quality ... in oncology and/or R195 intensive care, and take part in regular training of oncology and intensive care nurses The nurse/patient ratio ranges from 1.2 to 1.7 Routine clinical rounds, including ... mix of patients (e.g type of tumour, number of BMT patients, disease status and extent, and level of ICU support) In particular, the prognosis for cancer patients receiving MV is very poor In...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: "Clinical review: Specific aspects of acute renal failure in cancer patients" pot
... develops in 20% to 40% of BMT recipients [47] Amphotericin during conditioning Acyclovir during conditioning Vancomycin during conditioning The main site of liver damage in this setting is the ... Intern Med 1990, 150:1693-1695 Available online http://ccforum.com/content/10/2/211 20 Ying WZ, Sanders PW: Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein ... uricolytic treatment in patients with a high risk of acute TLS, prevention of contrast nephropathy, elimination of nephrotoxic drugs in high-risk patients, and monitoring of serum methotrexate...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients
... digoxin in Japanese patients The serum levels of Cys-C and Cr in the patients were higher than those in the healthy elderly subjects, but the increase of Cys-C was more predominant in the patients, ... Limitations of creatinine as a filtration marker in glomerulopathic patients Kidney Int 1985; 28(5):830–838 Perrone RD, Madias NE, Levey AS Serum creatinine as an index of renal function: new insights into ... Factors influencing the prediction of steady state concentrations of digoxin Biol Pharm Bull 2001; 24(4):403–408 22 Cockcroft DW, Gault MH Prediction of creatinine clearance from serum creatinine...
Ngày tải lên: 31/10/2012, 17:08
Báo cáo y học: "Study of urban community survey in India: growing trend of high prevalence of hypertension in a developing country"
... participants are of great interest since chance of progression to hypertension is high Incidentally the previous study has shown increasing prevalence of coronary artery disease among young in India [26] ... significant influence on prevalence of hypertension The relation of hypertension with advancing of age and BMI has already been documented in the past among Indian subjects [4] The point of interest ... ranging from 1.24% in 1949 to 36.4 % in 2003 and for rural people from 1.99% in 1958 to 21.2% in 1994 [1] However differential rates are due to different cut off marks in determining the level of...
Ngày tải lên: 02/11/2012, 11:12
báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... cancer and independently associated with the increased risk of colorectal cancer in men [14], and overall cancer risk [15] Interleukin-6 (IL-6) has been used for the diagnosis of colorectal cancer ... Identifying Immune Oscillatory Cycles in Advanced Cancer using L-CRP Single measurements of CRP or L-CRP have previously been used to correlate with the risk of certain cancers, prognosis or cancer ... Timing of Vaccinations with the CRP cycle in a patient with advanced melanoma Timing of Vaccinations with the CRP cycle in a patient with advanced melanoma Multiple fortnightly doses of vaccine...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Pictorial Representation of Illness and Self Measure Revised II (PRISM-RII) – a novel method to assess perceived burden of illness in diabetes patients" pptx
... J: Validating PRISM (Pictorial Representation of Illness and Self Measure) as a Measure of Suffering in Chronic Non -Cancer Pain Patients J Pain 2008 in press Büchi S, Buddeberg C, Klaghofer R, ... amount of suffering These differences in distribution also argue in favour of measuring suffering with a visual and indirect method such as the PRISM-RII The PRISM has been proven useful in measuring ... representation of illness: A novel method of measuring patients' perception of the impact of illness Psychother Psychosom 1998, 67:222-5 Pincus T, Morley S: Cognitive-processing bias in chronic pain: a...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients" pdf
... and in response to changing circumstances [4] Individualised measures of QoL (IQoL) increase respondents' discretion in selecting the domains most important to their QoL and, in determining the ... change in the meaning of one's evaluation a construct as a result of a change in one's internal standards of measurement, a change in one's values, or a change in one's definition of the construct ... Schedule for Evaluation of Individual Quality of Life (SEIQoL) [7] may prove useful in determining the impact of response shift on the assessment of treatment effects in clinical trials The present...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" Cross-cultural development of an item list for computer-adaptive testing of fatigue in oncological patients" potx
... Treatment of Cancer QLQ-C30: a quality -of- life instrument for use in international clinical trials in oncology J Natl Cancer Inst 1993, 85(5):365-76 17 Cella DF, et al: The Functional Assessment of Cancer ... committees of centers contributing patients The patient interviews helped to pre-test item wording (e.g whether the items are confusing, intrusive, difficult, upsetting or annoying) and to find out ... pre-testing in cancer patients • Construction of an item list for international field testing Methods An overview on the EORTC CAT development strategy is given by Petersen et al [22] In the main,...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" Pictorial Representation of Illness and Self Measure Revised II (PRISM-RII) – a novel method to assess perceived burden of illness in diabetes patients" pdf
... J: Validating PRISM (Pictorial Representation of Illness and Self Measure) as a Measure of Suffering in Chronic Non -Cancer Pain Patients J Pain 2008 in press Büchi S, Buddeberg C, Klaghofer R, ... amount of suffering These differences in distribution also argue in favour of measuring suffering with a visual and indirect method such as the PRISM-RII The PRISM has been proven useful in measuring ... representation of illness: A novel method of measuring patients' perception of the impact of illness Psychother Psychosom 1998, 67:222-5 Pincus T, Morley S: Cognitive-processing bias in chronic pain: a...
Ngày tải lên: 20/06/2014, 16:20
báo cáo hóa học:" Clinical and psychological correlates of healthrelated quality of life in obese patients" ppt
... Scores on the Binge Eating Scale (BES) were in a range suggestive of binge eating in over one fourth of subjects, while over 10% of patients had BES scores indicative of binge eating disorder Mean ... [21] The Binge Eating Scale was used to detect binging [22]; values in the range 17-26 were considered suspect of binge eating, whereas values ≥ 27 were taken as predictive of Binge Eating Disorder ... impact of physical conditions on HRQL The choice of questionnaires in different settings should take into consideration the domains of greater interest (physical vs psychological) in individual...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo hóa học: " The prevalence of polypharmacy in elderly attenders to an emergency department - a problem with a need for an effective solution" doc
... Banerjee et al International Journal of Emergency Medicine 2011, 4:22 http://www.intjem.com/content/4/1/22 Page of We extracted the following information, using a structured form, in patients aged ... warfarin is used in a significant number of elderly patients, we were unable to find any drug combinations leading to potential adverse interaction with warfarin usage This may be because of the ... close level of monitoring of therapeutic anticoagulation in dedicated anticoagulation clinics in the hospital, and of wider awareness of the potential for drug interactions with warfarin • Hospital...
Ngày tải lên: 21/06/2014, 03:20
Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx
... suggesting that the elevation of IL-4 production during an ongoing immune response to tumor can down-regulate Th1 cytokine production Therefore, in gastrointestinal cancer patients, the initial ... lymphocytes in patients with gastrointestinal cancer, there is no corresponding decrease in the frequency of Th1 cells Impaired host immunity or excessive stress after major surgery often increases ... Casciani CU: Distribution in Th1 and Th2 subsets of CD4+T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression Cancer Immunol Immunother...
Ngày tải lên: 09/08/2014, 04:21
Báo cáo y học: "Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes" ppt
... the detection of this antibody [14] In the present report we screened for anti-fibrillarin by ALBIA using purified recombinant fibrillarin protein, yielding an autoantibody frequency of 14% All ... Targoff IN, Trieu EP, Miller FW: Reaction of anti-OJ autoantibodies with components of the multi-enzyme complex of aminoacyl-tRNA synthetases in addition to isoleucyl-tRNA synthetase J Clin Invest ... O'Brien CA, Frank MB, Targoff IN: Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen J Clin Invest 1995, 96:1730-1737 Page 13 of 13 (page number not for...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc
... reported in the individual studies This pattern included a clear increase in risks of lung cancer and lymphoma, both Hodgkin and non-Hodgkin, and a potential decrease in risks of colorectal cancer ... solid tumors or colorectal cancer Franklin and colleagues [8,9] observed no increase in overall malignancy excluding non-melanoma skin cancer but saw an increase in lymphoma in their early RA population ... colorectal, and breast cancer) in patients with RA in the recent published literature In particular, this review focused on observational studies comparing the incidence of malignancy in patients with...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Functional characterization of Trip10 in cancer cell growth and survival" ppsx
... Trip10 and huntingtin to colocalize and form perinuclear foci In contrast, while overexpression of Trip10 in CP70 cells also increased huntingtin levels, both proteins remained in the cytosol ... metastasis in mice inoculated with Trip10-overexpressing IMR-32 cells (Figure 4A) On the other hand, huntingtin increases cell death by promoting apoptosis Thus, high levels of huntingtin in Trip10overexpressing ... have profound effect in the cell type-specific functions of Trip10 Discussion Trip10 was initially identified as a Cdc42-interacting protein involved in GLUT4-mediated glucose uptake in adipocytes...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps
... http://www.jhoonline.org/content/4/1/3 Author details Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China Guandong General Hospital, Guandong, China 3Beijing Cancer Hospital, Beijing, China 4Cancer ... CYP3A inhibitors or inducers within days before starting study drug All patients gave written informed consent before study entry according to the Good Clinical Practice guidelines of the International ... Targeting von HippelLindau pathway in renal cell carcinoma Clin Cancer Res 2006, 12:7215-7220 Yuan R, Kay A, Berg WJ, Lebwohl D: Targeting tumorigenesis: development and use of mTOR inhibitors in cancer...
Ngày tải lên: 10/08/2014, 21:23