predictive value of clinical parameters and biopsy findings

... Number of computed tomography pulmonary angiogram (CTPA) studies, ddimer assays, and diagnoses of pulmonary embolism (PE) Table D-dimer assay and CTPA sensitivity, specificity and predictive values ... evidence of PE Data were collected for presence or absence of PE and the type of PE, whether a d-dimer assay was performed and the d-dimer result if applicable Patients’ age and gender and other ... The investigation has high predictive value, but is resource and time intensive and exposes patients to considerable radiation Our aim was to assess the potential value of a negative d-dimer assay...

Ngày tải lên: 21/06/2014, 19:20

... fact that clinical trials establishing the activity of these agents in RCC represent landmark studies, between a third and two-thirds of patients (depending on prognostic factors and clinical ... laboratory model systems of RCC will lead to the prioritization of predictive biomarkers for sunitinib and everolimus in the validation cohorts of the E-PREDICT and S-PREDICT/PREINSUT clinical trials ... development of the next generation of predictive biomarkers across a wide range of solid tumor types Integration of personalized functional genomics into the clinical setting The generation of personalized...

Ngày tải lên: 11/08/2014, 12:20

... families, about half of 117 which met the Amsterdam criteria, a high proportion of both polyps and CRC showed mutation of BRAF and ⁄ or methylation of the CIMP marker MINT31 Many of the polyps were ... immunohistochemistry for MLH1] The glands to the left are normal and show nuclear expression of both MGMT and MLH1 The gland with features of serrated adenoma and the poorly differentiated adenocarcinoma ... and CRC as described above Molecular alterations occurring at the key transition from hyperplasia to dysplasia include loss of expression of MLH1 in group CRC and loss of expression of MGMT and...

Ngày tải lên: 22/03/2014, 17:20

... Professor of Medicine, Oncology and Blood and Marrow Transplantation, at Stanford University She is also the president of the American Society of Clinical Oncology, and a great friend to all of ... AMERICAN SOCIETY OF CLINICAL ONCOLOGY AND THE INSTITUTE OF MEDICINE Ellen Stovall, Vice Chair, Committee on Cancer Survivorship: Improving Care and Quality of Life; and President and CEO, National ... Head and Professor of Medicine and Health Policy and Professor of Pediatrics at George Washington University I am delighted to introduce them both here to you today INTRODUCTORY REMARKS Sandra...

Ngày tải lên: 22/03/2014, 20:21

... Hyperandrogenaemia was defined on the basis of high serum androgen levels, mainly testosterone (≥0.6 ng/ml) and androstenedione (≥3.0 ng/ml) Clinical hyperandrogenism was defined by the presence of ... possible routinary clinical feasibility of ultrasounds ovarian stromal evaluation and its correlation with androgens, insulin resistance (HOMA test), and instrumental and metabolic makers of early atherosclerosis ... by Stein and Leventhal [12], and doubling of cross-sectional ovarian area, observed by ultrasound, has been shown to be expression of a marked increase (33%) of cortical portion, and of a five-fold...

Ngày tải lên: 20/06/2014, 07:20

... norovirus and influenza virus treatments Widening the range of drugs available for the treatment of HIV infection is a highly active and critically important field of research The preclinical steps of ... complications Peg-IFN and ribavirin in the standard dosage (Peg-IFN alpha-2b 1.5mg/kg & ribavirin 800-1000mg for genotypes and 3, and 1000-1200mg for genotypes and 4) for the standard duration of time (48 ... then the value for serum creatinine used should be 4.0 Any value less than one is given a value of (i.e if bilirubin is 0.8, a value of 1.0 is used) This helps prevent the occurrence of scores...

Ngày tải lên: 27/06/2014, 10:20

... of soil material (body/toe) Clay mud, clay sand, clay, sand dust /dust sand Clay mud, clay sand, average sand, dust clay /dust sand Clay mud, average sand, dust clay / Cohesive average sand and ... average sand, dust clay / discrete average sand Gravel fine sand, gravel clay, sandy clay/dust sand Gravel fine sand, gravel clay/average dust sand Cohesive and Mud, clay, clay sand/Clay sand discrete ... 8.041 Clay, clay sand/Dust sand and Km17+017 discrete Ca Tre Nho Bridge, Clay mud, sand clay, clay CT6 54,4/1,2 11.673 Km17+677 sand/Gravel clay sand Clay mud, sand clay, clay sand/ CT7 38,1/1,0...

Ngày tải lên: 02/07/2014, 20:32

... disintegration of a wider network For example, it is possible that activation of Cg25 supports activation of the DMN and deactivation of Cg25 supports deactivation of the DMN and activation of the ON ... was done to facilitate an understanding of Freudian terminology and allow for the application of these ideas to areas of clinical interest Modern clinical research and older empirical work such ... http://www.annals-general-psychiatry.com/content/7/1/9 Interestingly, sudden and dramatic deactivations of Cg25 and functionally related regions of the vmPFC and OFC have recently been recorded after intravenous infusion of the dissociative hallucinogen...

Ngày tải lên: 08/08/2014, 23:20

... years) with 70 SCC of glottic larynx and 49 SCC of hypopharynx were determined Complete clinical data of all patients were available Table shows the distribution of cases and main clinical characteristics, ... and in a lower number, SCC of hypopharynx may develope metastases early in the course of disease Own investigations revealed metastases in up to 41% of a series of glottic SCC and up to 92% of ... involvement, stage and size of the tumor, and survival Sensitivity and specificity were calculated Data were processed by Microsoft Excel and SPSS for descriptive statistic values, Student's t-test,...

Ngày tải lên: 09/08/2014, 04:21

... considered as categories: pT < and pT > Presence of mucorrhea and anismus, hematocrit value ranging between 16,7% and 31%, WBC count between 4500 and 5800/mm3 and fibrinogen value > 400 mg/dl were significantly ... symptoms and major medical problems of patients; laboratory data and neoplastic markers values; location, size, endoscopic appearance and preoperative staging of the tumour; operation type, degree of ... also that radical resection and type of operation are important prognostic factors In a recent Table 2: Results of multivariate analysis of clinical and laboratory data of patients with colon cancer...

Ngày tải lên: 09/08/2014, 07:21

... esophagus and mainstem bronchus were 25 Gy (range, 11 - 39 Gy) and 42 Gy (range, 30 - 49 Gy), respectively Early Clinical and Radiographic Response All patients underwent clinical follow-up, and 14 ... declines in the maximum standardized uptake values (Figure 1) Local Control and Survival Despite excellent early clinical and radiographic responses, local control and survival outcomes beyond ... treatment volume; and SUVMAX: maximum standardized uptake value; Author details Department of Radiation Medicine, Georgetown University Hospital, Washington, DC, USA 2Division of Hematology and Oncology,...

Ngày tải lên: 10/08/2014, 22:21

... of back pain and leg pain, and functional disability (Table 1) The median age for both groups was 48 years and there was almost an even distribution of men and women The median for leg pain and ... collection and the analysis, and main parts of the manuscript CM participated in the design and coordination of the study and helped to draft the manuscript CLY participated in the conception and made ... retrieve information on, and compare the duration of, treatment, number of contacts with clinicians, and referral for surgery that occurred before and after the practice of routine MRI However,...

Ngày tải lên: 13/08/2014, 14:20

... nosocomial), and the predictive value for outcome of the first PCT concentration and the decrease in PCT after treatment in this large population of patients with severe sepsis Page of 10 score and SAPS ... study and this substudy, analyzed the data, and wrote the initial manuscript VP and ER contributed the idea and design of the Finnsepsis study and this substudy and contributed to the drafts of ... University of Eastern Finland and Eastern Finland Laboratory Centre, Puijonlaaksontie 2, 70211 Kuopio, Finland 3Division of Anaesthesia and Intensive Care Medicine, Department of Surgery, Helsinki...

Ngày tải lên: 14/08/2014, 07:21

... and integrating of software packages MIX and ASREML and also checked programs and results GT participated in setting up the design and conception of the study, helped to discuss the results and ... overall breeding value of each animal was the sum of a 'residual polygenic breeding value' and a 'QTL breeding value' A single biallelic QTL with an allele frequency of 0.5 was assumed and the QTL ... examine the impact of the different models on the estimation of MA-BLUP breeding values, the correlation of true and estimated breeding values was calculated for each group of animals (bulls,...

Ngày tải lên: 14/08/2014, 13:21

Ngày tải lên: 26/03/2015, 10:59

... the Ct values against the logarithm of the copy number Also, slope and coefficient of determination of the calibration curve and efficacy of the reaction was calculated Melting temperature of the ... at which 50% of DNA is dissociated (Handbook of ABI® StepOneTM Plus) A validation of real-time PCR protocol was based on the determination of the level of detection and the level of quantification ... Comparison of mycelium growth of ten benzimidazole-sensitive and ten -resistant isolates of Botrytis cinerea at four combinations of temperature and nutrition medium 115 Table 7-18 Comparison of...

Ngày tải lên: 19/11/2015, 15:46

... Distinguished Engineer and a member of the IBM Academy of Technology He assists clients in the design and implementation of IT management systems to maximize the value of their IT investment and improve ... opportunities and services as part of IBM’s broad portfolio of cloud computing offerings During his tenure at IBM, Telford has played a number of key roles in various software and service initiatives ... and methodologies are in place, and that every individual in the organization is aware of their responsibility in regard to the safety and integrity of data Finally, when implementing tools and...

Ngày tải lên: 06/12/2015, 23:16

... explanations for the limited predictive value of physical fitness for falls are described below In order to find a predictive value of physical fitness for falls, the number of falls should increase ... Information on the history of fractures and the presence of spasticity of the legs, heart condition (arrhythmias and coronary heart disease), epilepsy, visual impairments, and polypharmacy was retrieved ... the 30s Chair stand test (30sCS) (Rikli & Jones, 2001) Participants had to stand upright and sit down again as often as possible in 30 s without using their hands The total number of complete stances...

Ngày tải lên: 25/08/2016, 23:24

... Surtronic 3Cprofilometer and Mitutoyo SJ-digital surface analyzer, using a trace length of 4.8 mm, a cut-off length of 0.8 mm, and an M1 band-pass filter The surface roughness values were recorded ... structure of neural network, representation of data, normalization of inputs– outputs and appropriate selection of activation functions have strong influence on the effectiveness and performance of ... with Bayesian regularization yields important parameters such as sum of square errors (SSE), sum of squares of weights (SSW) and number of effective parameters used in neural network, which can...

Ngày tải lên: 24/11/2016, 10:43

... memory of Professors Howard Rogers and John Trounce, two of the three authors of this textbook’s first edition COMPANION WEBSITE The fifth edition of A Textbook of Clinical Pharmacology and Therapeutics ... the most useful but also one of the most dangerous activities of our professional lives Understanding the principles of clinical pharmacology is the basis of safe and effective therapeutic practice, ... discussion of the exciting new concept of personalized medicine Adverse drug reactions and the use of drugs at the extremes of age and in pregnancy are covered, and the introduction of new drugs...

Ngày tải lên: 11/12/2016, 22:08