preclinical models of head and neck squamous cell carcinoma

... Cullen KJ: Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging Curr Opin ... scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, ... Prognostic impact of HER-2/neu expression on squamous head and neck carcinomas Head Neck 2007, 29:655-664 Wei Q, Sheng L, Shui Y, Hu Q, Nordgren H, Carlsson J: EGFR, HER2, and HER3 expression...

Ngày tải lên: 18/06/2014, 22:20

... Cullen KJ: Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging Curr Opin ... scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, ... Prognostic impact of HER-2/neu expression on squamous head and neck carcinomas Head Neck 2007, 29:655-664 Wei Q, Sheng L, Shui Y, Hu Q, Nordgren H, Carlsson J: EGFR, HER2, and HER3 expression...

Ngày tải lên: 20/06/2014, 04:20

... pathologically and reviewed within the multidisciplinary head- and- neck team As part of the study, the imaging of the all patients who experienced LRR was reviewed by a head and neck specialist ... intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 2003, ... radiotherapy in head and neck cancer: a meta-analysis Lancet 2006, 368:843-854 Lee N, Puri DR, Blanco AI, Chao KS: Intensity-modulated radiation therapy in head and neck cancers: an update Head Neck 2007,...

Ngày tải lên: 09/08/2014, 09:20

... Malvern Instruments Ltd., UK) 2.2 Cell Culture The head and neck squamous carcinoma cell line UMBSCC-745 was kindly provided by Dr Robert Mandić, Department of Otolaryngology, Philips University, ... comparable to other cancer cells, e.g cervical adenocarcinoma cells [43], osteosarcoma cells [42], lung adenocarcinoma cells [37,41], and gastric and colon cancer cells [44] Despite this, nanoparticle ... recurrent/metastatic head and neck cancer Ann Oncol 21(Suppl 7):vii252-vii261 Berrino F, Gatta G: Variation in survival of patients with head and neck cancer in Europe by the site of origin of the tumours...

Ngày tải lên: 11/08/2014, 00:23

... C, Carey T, et al.: Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients Clin Cancer Res ... applications of microarrays in head and neck cancer research Laryngoscope 2004, 114:241-248 Choi P, Chen C: Genetic expression profiles and biologic pathway alterations in head and neck squamous cell carcinoma ... University of Michigan series head and neck squamous cell carcinoma (survival

Ngày tải lên: 14/08/2014, 07:21

... Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas Journal of Translational Medicine 2011 9:139 Page of Submit your next manuscript to BioMed Central and take full advantage of: • ... 31 Wild C, Brandau S, Lindemann M, Lotfi R, Hofmann TK, Lang S, Bergmann C: Toll-like receptors in regulatory T cells of patients with head and neck cancer Arch Otolaryngol Head Neck Surg 2010, ... Szyfter W, Zeromski J, Whiteside TL: Triggering of Tolllike receptor expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack Cancer...

Ngày tải lên: 18/06/2014, 22:20

... Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas Journal of Translational Medicine 2011 9:139 Page of Submit your next manuscript to BioMed Central and take full advantage of: • ... 31 Wild C, Brandau S, Lindemann M, Lotfi R, Hofmann TK, Lang S, Bergmann C: Toll-like receptors in regulatory T cells of patients with head and neck cancer Arch Otolaryngol Head Neck Surg 2010, ... Szyfter W, Zeromski J, Whiteside TL: Triggering of Tolllike receptor expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack Cancer...

Ngày tải lên: 20/06/2014, 04:20

... Facts and Figures 2009 Chen Y, Chen C: DNA copy number variation and loss of heterozygosity in relation to recurrence of and survival from head and neck squamous cell carcinoma: A review Head & Neck ... Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays ... association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas Genes...

Ngày tải lên: 10/08/2014, 09:22

... C, Carey T, et al.: Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients Clin Cancer Res ... sensitivity in head and neck squamous cell carcinoma lines Head Neck 2003, 25(8):654-661 Ongkeko WM, Altuna X, Weisman RA, Wang-Rodriguez J: Expression of protein tyrosine kinases in head and neck squamous ... Ricker JL, Chen Z, Van Waes C: Role of activated nuclear factor-kappaB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck Head Neck 2007, 29(10):959-971 Lee TL, Yang...

Ngày tải lên: 14/08/2014, 08:20

... unresectable squamous cell carcinoma of the head and neck region, have no synchronous primary tumors, and be ≥18 years old In addition, the patients had to have a performance status (PS) of ≤2 on ... intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 2003, ... chemoradiotherapy for head and neck cancer Curr Opin Oncol 2002, 14:323-329 Pignon JP, Bourhis J, Domenge C, Designe L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: ...

Ngày tải lên: 18/06/2014, 19:20

... unresectable squamous cell carcinoma of the head and neck region, have no synchronous primary tumors, and be ≥18 years old In addition, the patients had to have a performance status (PS) of ≤2 on ... intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 2003, ... chemoradiotherapy for head and neck cancer Curr Opin Oncol 2002, 14:323-329 Pignon JP, Bourhis J, Domenge C, Designe L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: ...

Ngày tải lên: 20/06/2014, 03:20

... diagnosis and management of head and neck cancer Overview of treatment of the primary tumour and neck This section addresses the first line treatment of head and neck cancer Management of recurrent ... the recognition and management of acute and late radiation toxicity 29 diagnosis and management of head and neck cancer 10 Treatment: palliation of incurable disease Head and neck cancer may ... identified to support the use of chemotherapy alone as a curative treatment for squamous carcinoma of head and neck In patients with head and neck cancer the administration of chemotherapy in combination...

Ngày tải lên: 14/02/2014, 22:20

... Guide to NECK DISSECTION CLASSIFICATION AND TNM STAGING OF HEAD AND NECK CANCER Committee for Head and Neck Surgery and Oncology American Academy of Otolaryngology– Head and Neck Surgery Neck Dissection ... of: Pocket guide to neck dissection classification and TNM staging of head and neck cancer / Committee for Neck Dissection Classification, American Head and Neck Society [and] Committee for Head ... III Sharma, Anand K IV Kies, Merrill S V American Academy of Otolaryngology Head and Neck Surgery Committee for Head and Neck Surgery and Oncology VI American Head and Neck Society Neck Dissection...

Ngày tải lên: 15/03/2014, 00:20

... mucosal surface of the lip DIAGRAM OF THE HEAD AND NECK Oral cavity Oropharynx Larynx Hypopharynx ALL HEAD AND NECK CANCERS DIAGRAM OF THE LYMPH NODES LEVELS IN THE NECK I II III VI IV V NECK DISSECTION ... within two weeks of urgent referral DIAGNOSIS AND STAGING D Fine needle aspiration cytology should be used in the investigation of head and neck masses D All patients with head and neck cancer should ... areas of metastatic disease in patients with head and neck cancer should include: number of involved nodes level of involved nodes extracapsular spread of tumour type of nodal dissection size of...

Ngày tải lên: 15/03/2014, 01:20

... Williamson SK, Von Hoff DD: Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous- cell carcinoma of the head and neck: a Southwest ... II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-dailyreirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation ... report of RTOG 9610, a multiinstitutional trial ofreirradiation and chemotherapy for unresectable 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 recurrent squamous cell carcinoma of the head and neck...

Ngày tải lên: 09/08/2014, 09:21

... 40% of the SUV similarly to what proposed by other authors for lung and also head and neck tumors [10,26,27] Conclusion The present study shows that FDG-PET/CT images for primary head and neck carcinoma ... http://www.ro-journal.com/content/3/1/29 ment planning also of patients with head and neck carcinoma [17-20] the extra laryngeal and pre-epiglottic space, and the thyroid gland In our experience, the primary tumor ... scenario of imaging for radiotherapy of head and neck tumors may include the use of functional imaging such as FDG-PET/CT with the aim to characterize the biological features of the tumor and optimize...

Ngày tải lên: 09/08/2014, 09:22

... control of the primary site, biopsy proven squamous cell carcinoma (SCC), Karnofsky performance 60 and above, possibility of surgical resection no evidence of distant metastasis A total of 21 patients ... concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: a systematic review of the published literature with subgroup analysis Head Neck 2001, 23:579-589 Hinerman ... Postoperative irradiation for squamous cell carcinoma of the oral cavity: 35-year experience Head Neck 2004, 26(11):984-94 Argiris A: Update on chemoradiotherapy for head and neck cancer Curr Opin Oncol...

Ngày tải lên: 09/08/2014, 10:21

... papillomavirus type 16 and squamous cell carcinoma of the head and neck Clin Cancer Res 2002, 8:3187-3192 Semple CJ: The role of the CNS in head and neck oncology Nurs Stand 2001, 15(31):39-42 ... http://www .head- face-med.com/content/7/1/9 Page of Figure Annual frequency of broad histological types of head and neck malignancies Table Gender distribution of broad histological types of head and neck ... report of Hoffman et al [17] who also found that lymph nodes of the head and neck were the most common sites for lymphomas Sarcomas of the head and neck had an overall male: female ratio of 1.5:1...

Ngày tải lên: 11/08/2014, 20:21

... (HNSCC): head and neck squamous cell carcinoma; (HCII): Hybrid Capture; (OSCC): Oral squamous cell carcinoma Acknowledgements Authors are thankful to persistent efforts of an enthusiastic group of ... papillomavirus and a subset of head and neck cancers J Natl Cancer Inst 2000, 92(9):709-20 Kreimer AR, Clifford GM, Boyle P, Franceschi S: Human papillomavirus types in head and neck squamous cell carcinomas ... of the head and neck [6] Kreimer et al reported that genomic DNA of oncogenic HPV has been detected approximately 26% of all OSCC of the head and neck worldwide [7] but the most accurate and consistent...

Ngày tải lên: 12/08/2014, 01:22