preclinical animal models for segmental bone defect research and tissue engineering

... extension for traits: X and Y To obtain BLUP for X and Y the additive covariance matrices for traits X and Y, and between traits X and Y are needed The covariance matrix for traits X and Y can ... groups for breed I and for L The model of evaluation includes fixed effects of age (as a covariate), sex and genetic groups (Al, A2 and B), and random BV for animals through In order for [X:ZQ] ... and a are the additive covariances for traits X and Y L ) XY ( A I > x < Y A in populations L and I, respectively, and a is the additive segregation LI ) XY ( A covariance for populations L and...

Ngày tải lên: 09/08/2014, 18:22

... !i)/!! and or the 0’ error standard deviation (sire model) environmental standard deviation (animal model) For the heritability value of 0.20 the estimators from the sire model and the animal ... use of equivalent sire and animal models for the underlying variable and the use of the same estimation method lead to different estimators may be counterintuitive Under the animal model the maximum ... with mean and variance Q the joint posterior density u, has the form ( C1 constant): = Using a probit-transformation and a purely additive genetic model underlying variable (4l: standardized...

Ngày tải lên: 09/08/2014, 18:22

... mesoderm Therefore, it appears that the function of cad in the growth zone and in posterior segmentation is ancestral for bilaterians (animals with bilateral symmetry, including both insects and vertebrates) ... long germ-band insect with simultaneous segment formation However, bicoid is a phylogenetically young gene that evolved late and only in flies It does not exist in other long-germ band insects, ... 6, Issue 1, Article 303 refereed research interactions information Genome Biology 2004, 6:303 deposited research Although short, the meeting reflected well how information from non-model organisms...

Ngày tải lên: 14/08/2014, 14:21

... and J Chan Comparative study of human MSCs from fetal bone marrow, umbilical cord, adult bone marrow and adult adipose tissue for bone tissue engineering International Society for Stem Cell Research, ... cortical bone and cancellous bone Cortical bone (or compact bone) is the dense bone found in shafts of long bones and forming a cortex or shell around vertebral bodies and other spongy bones Cortical ... Mattar, ESM Lee, LG Tan, MA Choolani and J Chan Development of Highly Osteogenic Bone Tissue Engineered Construct for Critical Bone Defect Healing Tissue Engineering and Regenerative Medicine International...

Ngày tải lên: 12/09/2015, 09:10

... Contents xiv 18.3 Interparticle forces in colloids and interfaces 18.3.1 Interparticle forces and colloids 18.3.2 Forces and colloid stability 18.3.3 Interparticle forces and adhesion 18.4 Acid–base ... Introduction 19.2 Models for Pharmaceuticals 19.2.1 General 19.2.2 The NRTL–SAC model 19.2.3 The NRHB model for pharmaceuticals 19.3 Models for amino acids and polypeptides 19.3.1 Chemistry and basic ... Chichester, West Sussex, PO19 8SQ, United Kingdom For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material...

Ngày tải lên: 18/02/2014, 15:20

... integrity and 211 performance of the male and female reproductive systems as well as growth and development 212 of the F2 generation For further information on developmental toxicity and functional ... provides general information concerning the effects of a substance on the 204 integrity and performance of the male and female reproductive systems, and on the growth 205 and development of the ... fluids and coagulating glands), levator ani-bulbocavernosus muscle, 363 paired Cowper's glands and the glans penis 364 In order to establish whether a test substance can have androgenic or antiandrogenic...

Ngày tải lên: 05/03/2014, 16:20

... y the vector of observations for q traits, β, u and e vectors of fixed effects, random effects and residuals, and X and Z the design matrices pertaining to β and u For simplicity, assume u represents ... equations for the sires and then the 16 progeny, with horizontal and vertical lines separating the blocks for fixed effects, sires and progeny For the MUV model, each diagonal block for animals ... matrices for all traits and did not allow for additional random effects; see, for instance, Jensen and Mao [57] for a review Hence, sophisticated schemes have been developed to augment the data and...

Ngày tải lên: 14/08/2014, 13:21

... is distributed over an even and flat terrain, and which can be improved to grow farm products and develop aquaculture Generally, the agricultural land and wetlands for aquaculture in this area ... eliminate hunger and reduce poverty for the farmers - Developing spatial organization of high effective economic models have created new awareness, and goods and market understanding for inshore farmers ... and drainage water system which ensures lighting and supplying electricity power and clean water for inhabitants Educational, healthcare and cultural networks of the town are being invested and...

Ngày tải lên: 22/03/2014, 12:20

... responsible for the report were chosen for their special competences and with regard for appropriate balance Support for this project was provided by the Agency for Health Care Research and Quality, ... Federation for Medical Research Foundation, New York, New York Francis Chesley, Director, Office of Research, Review, Education and Policy, Agency for Healthcare Research and Quality, Rockville, Maryland ... demand a role in the formulation of the research agenda and in the design, review, and pursuit of research In addition, consumers are taking a greater role in accessing health information and...

Ngày tải lên: 29/03/2014, 13:20

... male and female speakers); this set is used for adapting the baseline HMMs and the stateindependent GMM to the application context This phase is done once and we denote BDSON -models as the models ... adapt globally the state-independent GMM for a given state, using a unique and simple transformation This transformation (which is common for both the mean and the variance) is a linear function: ... includes 2712 commands uttered by 39 speakers; (ii) the second part for testing (VTEST): composed of 11136 utterances of commands uttered by 160 speakers As we performed voice command recognition...

Ngày tải lên: 21/06/2014, 20:20

... reduced For the baseline model, there are (for LOS) or (for NLOS) RVs, that is, (for LOS) or (for NLOS) random LSPs and the random XPR With SM-E, both DS and XPR are fixed as constants and only ... Table 3, that is, 26 for the indoor LOS scenario and 20 for the outdoor NLOS scenario For SM-E, the following parameters are not required: σDS , σXPR , and 10 (for LOS) or (for NLOS) cross-correlation ... Outage Capacity Broadband capacity are obtained by integrating the narrowband capacity over the entire bandwidth as in (5) The CDFs of MIMO capacity for the baseline and simplified models are depicted...

Ngày tải lên: 21/06/2014, 23:20

... WLP, SLP models and the PZLP and PLP models cascaded with a conventional LP model are quite competitive, however, toward higher pitch values, the HOLP and WLP models outperform the other models ... parts, the residual SFM performance is the best Again, the HOLP and WLP models yield better results than the LPAUTO and SLP models, which in turn outperform the PZLP and PLP models, cascaded with ... low as −90 (PLP) and −100 (PZLP) dB However, the PLP and PZLP models MSFE performance is seen to be worse for lower fundamental frequencies and SNR values The sensitivity of these models to the...

Ngày tải lên: 22/06/2014, 00:20

... basic definitions and facts about finite dynamical systems and their associated state spaces In Section we discuss multivariate and univariate finite field models for genetic networks and show that ... use these results to compute for each i = 1, , 30, the number z(i) such that αi + = αz(i) For example, since α5 = α2 + 1, we have α5 + = α2 and so z(5) = 2, and so forth See Table Definition ... f )(0, , 0) and for each i = 1, 2, , qn − 1, let Bi = (φα ◦ f )(a0,i , a1,i , , an−1,i ) where EURASIP Journal on Bioinformatics and Systems Biology Table 1: Zech Logs for F32 Coli is...

Ngày tải lên: 22/06/2014, 19:20

... and 1152 sentences, for evaluating the acoustic models We intended to build longer-length models for words and syllables for which a sufficient amount of training data was available To understand ... models and 5515 triphones The mixed-model recogniser for CGN consisted of 94 syllable models and 6366 triphones SPEECH RECOGNITION RESULTS Figures and show the recognition results for TIMIT and ... syllable models that were initialised with the canonical triphones and, therefore, needed more reestimation rounds to conform to it Figures and present the results for TIMIT and CGN The best performing...

Ngày tải lên: 22/06/2014, 19:20

... systems is carried out The models so constructed are categorized in three groups: models based on points, models based on shapes, and hybrid models combining points and shapes The systems of the ... the center of the pupil and the glint, and the model based on the center of the pupil and multiple glints On the other hand, the models based on shapes involve more image information; basically ... points in rm and rr can be found having the same distance Therefore, there is no unique solution and we have an indetermination (see A Villanueva and R Cabeza Models Image features Models based...

Ngày tải lên: 22/06/2014, 19:20

... coupling) and system bandwidth Physical MIMO channel models can further be split into deterministic models, geometry-based stochastic models, and nongeometric stochastic models Deterministic models ... of DFT steering matrices is appropriate only for uniform linear arrays at Tx and Rx STANDARDIZED MODELS Standardized models are an important tool for the development of new radio systems They ... suitable for the simulation of smart antennas and MIMO systems They are, at this time, the most general standardized channel models, and are not intended for specific systems The 3GPP/3GPP2 model and...

Ngày tải lên: 22/06/2014, 22:20

... scales j = 3, 4, and 5; (ii) Morlet: scales j = 3, 4, and 5, (iii) DOG: scales j = 1, 2, and 3; (iv) MHat: scales j = 2, 3, and 4; and (v) Quadratic b-spline function: scales j = 2, 3, and Figure shows ... QRS complex waveforms; two 2-state HMMs for the PQ and ST segments; two 3-state HMMs for the P wave; two 6-state HMMs for the T wave, and one 3-state HMM for the isoelectric line (ISO) We note ... of waveforms correctly detected, according to the labels made by a physician R V Andre˜o and J Boudy a Table 1: Comparative waveform segmentation precision in milliseconds (mean μ and standard...

Ngày tải lên: 22/06/2014, 23:20

... values are as follows: 5.4 frames for open door, 4.1 frames for close door, 3.3 frames for pour water, 2.0 frames for erase board, and 6.2 frames for pick up object and put down elsewhere SUMMARY ... recognition from stationary andmoving platforms, surveillance and monitoring, hyperspectral processing, image understanding, and commercial applications of image processing and understanding EURASIP Journal ... 2000, and the M.S degree in electrical and computer engineering from the University of Maryland, College Park, in 2003, where he is currently pursuing the Ph.D degree in electrical and computer engineering...

Ngày tải lên: 22/06/2014, 23:20

... comparison of irradiated and unirradiated planarian tissue to reveal neoblast-specific genes [7] PIWI gene expression and function in neoblasts Robust methods for in situ hybridization and gene knockdown ... neoblasts can persist and proliferate for many days following RNAi treatment, and that during this time their progeny can still migrate to wound sites and become incorporated into tissues, but they ... http://jbiol.com/content/8/8/70 and http://jbiol.com/content/9/2/15 doi:10.1186/jbiol223 Cite this article as: Bely AE, Sikes JM: Acoel and platyhelminth models for stem-cell research Journal of Biology...

Ngày tải lên: 06/08/2014, 19:21

... vector for gene delivery The obtained clinical data for should provide us with an outline of the strategy (target, vector choice and delivery route) for RA and provide new insights for further preclinical ... into the knee joint of DBA1/J mice before the onset of CIA dramatically reduced pannus formation (invasive tissue of fibroblast-like cells in cartilage and bone) and cartilage erosion as a result ... in animal models of arthritis This review focuses on the gene therapeutic strategies of restoring the cytokine balance and genetic synovectomy in animal models of RA, as summarized in Figs and...

Ngày tải lên: 09/08/2014, 01:24