... the interface linking calpain to skeletal muscle a-actinin Colocalization of microcalpain and a-actinin in myogenic cells Calpains and a-actinin were previously located in Z-disks [44], and adhesion ... proteins [25,51] Binding interface between Calp and ask was further located in this study Calpain binding structures were found within the 10 kDa C-terminal domain of the a-actinin molecule The inability ... our study proves the interaction between a-actinin and calpain and locates binding motifs within regions where the EF-hand domains of the protease and the cytoskeletal protein are concentrated...
... TINA In Proceedings of the August 1989 International Workshop in Parsing Technologies Pittsburgh, Pennsylvania Younger, D H 1967 Recognition and Parsing of Context-Free Languages in Time n Information ... noun, find one, and introduce a new edge consisting of a completed NP The edge predicted by the noun will look to the left for a determiner, find one, and also introduce a new edge consisting of ... Picky combines the standard chart parsing data structures with existing bottom-up and top-down parsing operations, and includes a probabilistic version of top-down filtering and over-the-top prediction...
... advantageous pharmacologic profile andin vivo administration results in high and sustained exposure in tumor tissue [49] It inhibits both mTORC1 and mTORC2, resulting in enhanced inhibition of p-Akt compared ... Phosphoinositide 3-kinase in disease: timing, location, and scaffolding Curr Opin Cell Biol 2005, 17:141-149 Marone R, Cmiljanovic V, Giese B, Wymann MP: Targeting phosphoinositide 3-kinase: moving ... targeting drugs in RCC cell lines was synergistic in all cell lines studied The dual PI3K/mTOR inhibitor NVP-BEZ235 that is currently in clinical development is highly active in RCC models, and...
... advantageous pharmacologic profile andin vivo administration results in high and sustained exposure in tumor tissue [49] It inhibits both mTORC1 and mTORC2, resulting in enhanced inhibition of p-Akt compared ... Phosphoinositide 3-kinase in disease: timing, location, and scaffolding Curr Opin Cell Biol 2005, 17:141-149 Marone R, Cmiljanovic V, Giese B, Wymann MP: Targeting phosphoinositide 3-kinase: moving ... targeting drugs in RCC cell lines was synergistic in all cell lines studied The dual PI3K/mTOR inhibitor NVP-BEZ235 that is currently in clinical development is highly active in RCC models, and...
... tested in both the angular and spatial domain, in two corresponding experiments In the first, the increment in the accuracy of surface normal estimation at a single point is demonstrated In the ... angle between v and n and d0 , α0 initial parameters in units of world length In the above equation, (cos ω)−1 normalizes for changes in posture, d/d0 for changes in distance and, as in Section 3, ... Sections and facilitates the integration of the two proposed approaches in a coarse to fine estimation of regions of interest within V In this system [17], V is initially approximated by a sweeping...
... help in preparing the final manuscript REFERENCES [1] IEEE Signal Processing Magazine, “Location is everything: positioning in wireless networks (a special issue),” IEEE Signal Processing Magazine, ... lies in signal processing Especially he is interested in direct-sequence code phase synchronization in hostile environment, adaptive antenna algorithms, and channel estimation and positioning ... participating in the design and development of advanced software-defined radio for Finnish defence forces Timo Br¨ ysy received his M.S degree in a 1991 and his Ph.D degree in 2000, both in physics...
... selection index p plays the same role in [21] as CD in (22] The increase of i induces a decrease of R, initially because of the decrease in the selection intensity, noted by Kennedy and Trus (1993), and ... or the design structure It would be interesting to determine the main cause of this low precision This would allow the precisions obtained in both reduced and complete models to be compared, ... modèle linéaire mixte / disconnexion / progrès génétique INTRODUCTION The problem of precisionand especially of disconnectedness in BLUP genetic evaluation, is becoming increasingly important in...
... LMO2-S can interact with all these partners including LDB1, GATA1, TAL1 and E47 in a similar manner, but the binding affinity can vary for LDB1[18] It remains uncharacterized in detail regarding how ... element arrangements within a typical LMO2 binding site (A) Sequences of promoter regions of GPA, VE-Cadherin and miR-142 Letters bigger andin red were indicated as E-box, andin blue as GATA site ... Austin, TX, USA) Induced expression of MBP-LMO2-L/-S recombinant protein and maltose affinity chromatography DH5α strains with plasmid pMAL-c2x/pMAL-LMO2-L/ -S were activated and cultured in L...
... expressed protein Auxin signaling F-BOX protein IV II 14 65 569 1750 CDS CDS CDS Glyma19g39420# Auxin signaling F-BOX protein II 65 1751 Glyma16g05500* Auxin signaling F-BOX protein II 46 2279 ... processes, including RNA editing, cleavage and splicing Soy_3 and Soy_16 may regulate plant organelle development by silencing genes encoding pentatricopeptide repeat-containing proteins Song et ... chloroplasts in seeds Genes encoding transketolase and carboxylase in these processes were identified as gmamiR1530 and gma-miR1536 targets, respectively Genes encoding PPR-containing proteins, which...
... Tutino et al.: Time needed to achieve completeness andaccuracyin bedside lung ultrasound reporting in Intensive Care Unit Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine ... participated in the coordination of the study and took part in the internal teaching programme GC and SB were the two seniors involved in report judgement, they also coordinated the teaching programme ... standard report scheme for LUS can help intensivists to improve completeness andaccuracy level of the examination reporting and it permits to follow the clinical course of chest pathology in...
... model and a sire model on - - BLUP AND CDs: AN OVERVIEW Let us consider a mixed model with a single random factor (and the residual effect): where b is the fixed effect vector, X the pertaining incidence ... incidence matrix, u the random effect vector, Z the pertaining incidence matrix, and e the residual vector The random factors are normally distributed with the following first and second moments: ... remarks are worth mentioning at this stage: and L’(Z’MZ)L have the same set of eigenvectors, since is a linear function of I and the inverse of a linear function of I and L’(Z’MZ)L The CDs can...
... operation if proper smoothing domains (edge based or node based) are constructed In addition, within strain smoothing, domain integration is transformed into boundary integration, and the stiffness ... strain smoothing domains and support domain wi (shaded) for a nodal shape function in the ES-FEM Figure 5.2 Illustration of edge-based smoothing domain (sd) and node categories in the ESm-XFEM in ... singularity in the vicinity of the crack tip, whereas Chapter studies a combined smoothed and extended finite element, in which the strain smoothing operation is introduced into the XFEM settings...
... sentences in tourism domain for development and test Their statistics are shown in Table We will tune training and decoding parameters on 06dev and report results on other sets 4.1 Training and Translation ... word links associated with any words within the phrase pair divided by the number of all word links associated with any words within the phrase pair An inconsistent link connects a word within the ... training data Starting from the collection of parallel training sentences, we build word alignment models in two translation directions, from English to Chinese and from Chinese to English, and...
... fragment containing the RING finger and ROQ domains (amino acids 1–337; Fig 4A), a fragment containing the ROQ domain and CCCH finger (amino acids 138–484; Fig 4B) and a fragment containing exclusively ... protein fragments in binding buffer containing lM ZnCl2 is indicated by ()) above the relevant lanes Binding after preincubation in binding buffer containing lM ZnCl2 but also in the presence of ... enhances RNA binding by increasing the basic nature of the domain The precise role of the ROQ domain, and ⁄ or the CCCH motif, in contributing to RNA binding remains to be determined in future detailed...
... as providing the next step in helping users to gain some understanding of the information in the documents once they are retrieved By facilitating better collaborations between MT and target- language ... for interpreting the source In our prototype, the MT output is obtained by querying Google’s Translation API2 In the interest of exploiting user interactions as a diagnostic tool for improving ... Terveen, and John Riedl 2007 Suggestbot: using intelligent task routing to help people find work in wikipedia In IUI ’07: Proceedings of the 12th international conference on Intelligent user interfaces,...
... complex in ribbon representation, with cystatin A in green and papain in blue Residues in the second binding loop of cystatin A mutated in this work are in red Papain residues involved in interactions ... cystatin A (stefin A) in ¨ the binding of target proteinases Characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4 mutants with papain, cathepsin B, and cathepsin ... Table Equilibrium and rate constants at 25 °C for the binding of cystatin A variants with substitutions in the second binding loop to papain, cathepsin L and cathepsin B Methods and experimental...
... (continued) Studies Using Measures of Linguistic Accuracy Study Independent Accuracy variable measure L1 Kobayashi & Rinnert (1992) Subjects L2 Level Reliability Intrarater Interrater Writing ... prompts), and the length, syntactic complexity, and linguistic accuracy of written responses He found no change in linguistic accuracy related to question type Linguistic accuracy was determined “by ... writing done at home (i.e., without time constraints) Kroll coded 33 different error types, giving the following information on error coding: 120 Language Learning Vol 47, No In closely examining...
... α-Al2O3 in the composite thick films and to examine the variations in crystallinity according to the changes in the mixing ratio The crystallite size of the α-Al2O3 in the films was calculated using ... pattern of the Al2O3 thick film showed peak broadening and decreased intensity in comparison with that of the Al2O3 starting powder as shown in Figure 1a This result can be explained by the presence ... tangent in the composite thick films made using the starting powder of 12 vol.% polyimide was caused by the rough surface and increased porosity of these films The increased surface area and open...