pre clinical assessment of targeted site specific therapy exploiting ultrasound and cancer chemotherapeutic drugs
Báo cáo y học: "Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV" pps
Ngày tải lên :
11/08/2014, 08:21
... immunogenicity: pre- clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV Journal of Immune Based Therapies and Vaccines 2011 9:2 Page of Submit ... University Cancer Center, Loma Linda, CA 92354, USA 4Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115 USA 5Division of Research Resources and Microbiology and ... Brockstedt DG: Impact of preexisting vector -specific immunity on vaccine potency: characterization of listeria monocytogenes -specific humoral and cellular immunity in humans and modeling studies...
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Tài liệu Pathophysiology and Clinical Aspects of Venous Thromboembolism in Neonates, Renal Disease and Cancer Patients Edited by Mohammed A. Abdelaal ppt
Ngày tải lên :
19/02/2014, 23:20
... the site of injury The presence of platelet microparticles at the site of blood vessel injury may contribute to this process by providing a large source of surface membrane for assembly of the ... Tissue factor exposed at site of endothelial injury and haemostasis Fig The interaction of MP of platelet and monocyte origin being recruited in thrombus formation at site of endothelial injury ... Disease and Cancer Patients the first week of life and it is likely that a number of these :events initially develop antenatally (Monagle et al., 2008; Veldman, 2008) Presenting symptoms and clinical...
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PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF VENOUS THROMBOEMBOLISM IN NEONATES, RENAL DISEASE AND CANCER PATIENTS pdf
Ngày tải lên :
27/06/2014, 09:20
... the site of injury The presence of platelet microparticles at the site of blood vessel injury may contribute to this process by providing a large source of surface membrane for assembly of the ... Tissue factor exposed at site of endothelial injury and haemostasis Fig The interaction of MP of platelet and monocyte origin being recruited in thrombus formation at site of endothelial injury ... Disease and Cancer Patients the first week of life and it is likely that a number of these :events initially develop antenatally (Monagle et al., 2008; Veldman, 2008) Presenting symptoms and clinical...
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báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
Ngày tải lên :
21/06/2014, 02:20
... article as: Wong et al.: In vitro and in vivo pre- clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers EJNMMI Research 2011 1:1 Submit ... ‘)(2) fragment: preclinical evaluation of a potential construct for the targeted radiotherapy of malignant glioma Nuclear Medicine and Biology 2004, 31:345-55 19 Delaloye B, Bischof-Delaloye A, ... μCi) of 86Y-CHX-A"-panitumumab F(ab’)2 and imaged and days post-injection of the RIC (c) Specificity was demonstrated by co-injecting 100 μg of panitumumab with the RIC and blocking uptake of the...
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báo cáo hóa học: " Clinical assessment of the physical activity pattern of chronic fatigue syndrome patients: a validation of three methods" pptx
Ngày tải lên :
18/06/2014, 19:20
... 'cut off' point the combination of sensitivity and specificity is optimal [21] The best cut off points for the IPAQ and the CFS-AQ were determined by calculating and computing sensitivity and specificity ... sensitivity of 64.6% was reached combined with a specificity of 65.2% (table 3) For the IPAQ the best predicted probability cut off was at 0.67 with a sensitivity of 70.1% and a specificity of 62.7% ... curves of the IPAQ, CFS-AQ and API predicting CFS-patients daily activity typology, best cut-off points of CFS-AQ and IPAQ marked with (black circle) different cut off points and find the point with...
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báo cáo hóa học: " A preliminary study of clinical assessment of left unilateral spatial neglect using a head mounted display system (HMD) in rehabilitation engineering technology" pdf
Ngày tải lên :
19/06/2014, 10:20
... validity of the results because of the small number of subjects There was also a limitation about discussion of concerning the mechanism of USN because of the damaged part of the brain and the ... midline of As the common clinical test for USN, in the first evaluation of the frequency of presence of neglect for ADL (Table 3), 75 percent of all subjects admitted a USN symptom in activities of ... prospects of brain-damaged patients are rendered more specific and realistic by a consideration of their behavioral strengths and deficits within a functional framework [14] The development of an...
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báo cáo hóa học:" Pre-surgical radiologic identification of peri-prosthetic osteolytic lesions around TKRs: a pre-clinical investigation of diagnostic accuracy" ppt
Ngày tải lên :
20/06/2014, 01:20
... expectations for the preservation of mobility and physical activity [7] While the vast majority of cases show good clinical outcome and improvement in post-procedural standard -of- life [7], implant ... comparison of the abilities of junior and senior radiologists to identify such lesions However, we believe that the range of experience of observers utilized here is representative of clinical ... projections offer no significant benefit in diagnosis and may represent unnecessary effort and radiation exposure These findings may be of clinical benefit in influencing the timing and aggressiveness of...
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Báo cáo y học: "DAS28 best reflects the physician''''s clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment" potx
Ngày tải lên :
09/08/2014, 06:23
... square root of the joint counts and the natural logarithm of CRP and ESR) Robustness of the discriminant analyses and logistic regressions was confirmed by the use of a random train and test set ... Sensitivity and specificity of the response scores compared with DAS28 set at equal specificity Sensitivity and specificity of the different response scores Sensitivity of DAS28 at the same specificity ... analysis of the DAS28 We plotted the ROC curve of the DAS28 in Fig and listed sensitivities and specificities in Table Also, predictive values and the accuracies of classification in function of the...
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Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot
Ngày tải lên :
09/08/2014, 09:20
... European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada Journal of the National Cancer Institute 2000, 92:205-216 ... Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results Radiation ... non-small cell lung cancer Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer 2007, 13 van der Voort van Zyp NC, Prevost JB, van der...
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Báo cáo khoa học: " Feasibility and early clinical assessment of flattening filter free (FFF) based stereotactic body radiotherapy (SBRT) treatments" pptx
Ngày tải lên :
09/08/2014, 09:21
... evaluation of the role of FFF beams in reducing involvement of organs at risk while preserving adequate target coverage is not aim of the present study Materials and methods Population of study ... from the end of the Evaluation of dosimetric and technical data For each group of patients, technical parameters of delivery were scored in terms of number of arcs, total number of monitor units ... toxicity) and the investigation of dosimetric and technical features of the treatments The objectives of this study were to evaluate feasibility and safety of SBRT with FFF beams Although, in hypofractionated...
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Báo cáo y học: "Ultrasonography, magnetic resonance imaging, radiography, and clinical assessment of inflammatory and destructive changes in fingers and toes of patients with psoriatic arthritis" pot
Ngày tải lên :
09/08/2014, 10:21
... ultrasonography, x-ray, and clinical examination, with MRI as standard reference method Sensitivities and specificities of US, x-ray, and clinical examination, with MRI as the standard reference method, ... Table Sensitivity and specificity of US, x-ray, and clinical examination, with MRI as the standard reference method US sensitivity US specificity X-ray sensitivity X-ray specificity Clinical examination ... moderate, 0.61 to 0.80 good, and 0.81 to 1.00 very good [12] MRI was used as the standard reference method for the calculation of the sensitivity and specificity of US, x-ray, and clinical examination...
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Báo cáo y học: "A geometric analysis of hallux valgus: correlation with clinical assessment of severity" pptx
Ngày tải lên :
10/08/2014, 21:23
... increase of 10 mm of DL causes decreases of 0.531° of HVA and 0.07° of IMA, and an increases of 0.04° of PPAA of the remaining angles for each case are maintaned unchanged The application of these ... Silvia, and Sandra for collecting measurements of clinical and radiological data, Richard and Marcos for analysis with Page of (page number not for citation purposes) Journal of Foot and Ankle ... the assessment of hallux valgus and based on previous findings of the correlation of the first metatarsophalangeal circumference with angular measurements [29], we here studied the position of...
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Báo cáo y học: "Objective Structured Clinical Examinations (OSCEs), psychiatry and the Clinical assessment of Skills and Competencies (CASC)Same Evidence, Different Judgement" ppsx
Ngày tải lên :
11/08/2014, 15:22
... that have investigated the validity of the use of OSCEs in clinical examinations of medical students and a full review of all of these is outside the scope of the current discussion In the main, ... episode of psychosis He has supervised and aided junior doctors sitting the CASC examination List of abbreviations OSCE: Objective Structure Clinical Examination; CASC: Clinical Assessment of Skills ... Skills and Competencies; MRCPsych: Membership of the Royal College of Psychiatrists UK Acknowledgements and Funding SM would like to acknowledge and thank Dr Matthew Broome (Associate Clinical Professor...
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Báo cáo khoa học: "Recombinant activated protein C: the key is clinical assessment of risk of death, not subset analysis" potx
Ngày tải lên :
12/08/2014, 23:21
... identifying risk of death prospectively: a clinical assessment of risk of death or APACHE II scoring? The PROWESS trial had no inclusion criteria related to clinical assessment of risk of death In ... which targeted the enrollment of patients with a clinical assessment of a low risk of death, the mortality was 25% in the APACHE II ≥ 25 group [4,6] This suggests that the key is clinical assessment ... assignment of clinical assessment of risk of death in the PROWESS trial, the effect of rhAPC in these patients would have been enhanced So the key to patient selection for administration of rhAPC...
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Anti inflammatory pharmacology of histone deacetylase inhibitors in pre clinical models of rheumatoid arthritis
Ngày tải lên :
11/09/2015, 09:16
... mechanisms of action of HDAC inhibitors Inhibition of RASF proliferation, suppression of proinflammatory cytokines, chemokines and NO as well as down-regulation of angiogenesis, chemotaxis and MMPs ... decreasing pain and inflammation as well as preventing and controlling joint damage and loss of function Current pharmacotherapy makes use of general analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), ... combination of TSA with low-intensity ultrasound modulated gene expression profile and enhanced the anti-inflammatory effects of TSA in RASFs [56] Consequently, there was reduced mRNA expression of inflammatory...
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Thermionics Quo Vadis? An Assessment of the DTRA’s Advanced Thermionics Research and Development Program pot
Ngày tải lên :
06/03/2014, 15:20
... believes that a firm understanding of the technical and programmatic history of past thermionic activities, of the technology’s successes and failures, and of programmatic and national policy issues ... independent assessment of its stewardship of the advanced thermionics research and development program and the technical progress of the program The NRC accepted the charge of performing this assessment ... stewardship of the advanced thermionics research and development program and of the technical progress of the program The NRC accepted the charge of performing this assessment The statement of task...
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Báo cáo " Classification and assessment of bioclimatic conditions for tourism, health resort and some weather therapies in Vietnam " pdf
Ngày tải lên :
14/03/2014, 15:20
... daylight in lowland area in term of assessment for development of tourism activities as well as existence of fog during the daylight in highland in term of assessment for health resort and some weather ... analysis and quantitative method, this paper presents the results of classification and assessment of bioclimatic conditions for two ultimate purposes: (i) for the development of tourism, excursion and ... conditions and these are the best places for human health in general and for tourism, excursion and sea vacation in particular Results and discussions The results of classification and assessment of...
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Báo cáo sinh học: " Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons" docx
Ngày tải lên :
18/06/2014, 22:20
... Region Figure Primer location and specificity of the RV2 QPCR assay Primer location and specificity of the RV2 QPCR assay Corresponding sequences from the end of ORF 60 and the adjacent intergenic ... Primer Express software, a set of primers (OSMa and OSMb; 76 bp amplicon) and a probe (OSM-FAM) were identified (Fig and Table 1) which could be used to detect OSM DNA from macaque, monkey and human ... of RFHVMn Using Primer Express software (Applied Biosystems), a set of PCR primers (RV2a and RV2b) and a probe (RV2-FAM) were identified for a TaqMan QPCR assay (71 bp amplicon) which would specifically...
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báo cáo hóa học:" Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons" pot
Ngày tải lên :
20/06/2014, 04:20
... Region Figure Primer location and specificity of the RV2 QPCR assay Primer location and specificity of the RV2 QPCR assay Corresponding sequences from the end of ORF 60 and the adjacent intergenic ... Primer Express software, a set of primers (OSMa and OSMb; 76 bp amplicon) and a probe (OSM-FAM) were identified (Fig and Table 1) which could be used to detect OSM DNA from macaque, monkey and human ... of RFHVMn Using Primer Express software (Applied Biosystems), a set of PCR primers (RV2a and RV2b) and a probe (RV2-FAM) were identified for a TaqMan QPCR assay (71 bp amplicon) which would specifically...
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