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Handbook of Public Policy Analysis Theory, Politics, and Methods pptx

Handbook of Public Policy Analysis Theory, Politics, and Methods pptx

... roots of this form of analysis, examine the logic and uses of CBA, and explore its use of contingent valuation in decisions aimed to improve social welfare. They also critique CBA as a form of ... professor of policy science at the Department of Political Science at the University of Amsterdam. He is also Director of the Amsterdam School for Social Science Research, and co- director of ... Public Policy, University of Birmingham, UK. He is also forums editor of the Journal of Critical Policy Analysis. Igor Mayer is an associate professor in the faculty of Technology, Policy and...

Ngày tải lên: 06/03/2014, 06:21

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)

... treatment of angina pectoris many years ago [2]; the pharmacological e ect of the dilation of the coronary arteries was found due to the action of nitrogen monoxide produced by decomposition of alkyl ... ingestion of 10–15 mL of each alkyl nitrite causes serious methe- moglobinemia [6].  e LD 50 value for an alkyl nitrite is reported to be 205 mg/kg.  ere are not many cases of analysis of alkyl ... eld of forensic toxicology. In this chapter, the methods for analysis of the compounds by headspace (HS)-gas chromatography (GC) and liquid-liquid extraction-GC are presented. Determination of...

Ngày tải lên: 18/10/2013, 00:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)

... Paasivirta J et al. (1981) Trace Analysis of Chemical Warfare Agents. An Approach to the Environmental Monitoring of Nerve Agents. Ministry of Foreign Affairs of Finland, Helsinki, pp 27, 28, ... metabolites of VX, could be detected [18]. GC/MS analysis for EMPA in serum. (a) a TIC and mass chromatograms; (b) an EI mass spectrum of the t-BDMS derivative of EMPA; (c) a CI mass spectrum of the ... stream of nitrogen gas at room temperature e . iii.  e residue is dissolved in 100 µL of the dichloromethane solution of DAEMO (IS solu- tion); a 1-µL of it is injected into GC/MS for analysis...

Ngày tải lên: 18/10/2013, 00:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)

... GC/MS analysis of ∆ 9 -THC-11-oic acid in human urine [15, 16]. e) A method of silylation of glassware to be done before analysis was reported [17]; such treat- ment suppresses the adsorption of ... 10:316–323 14) Yamamoto I (1992) Methods for analysis of cannabis and its components. In: The Pharmaceutical Society of Japan (ed) Standard Methods of Chemical Analysis in Poisoning – With Commentaries, ... spectra of ∆ 9 -THC-11-oic acid a er the TMS and methyl ester-TMS derivatizations. GC/MS analysis of ∆ 9 -THC-11-oic acid in urine 188 Cannabinoids and their metabolites GC analysis of cannabinoids...

Ngày tải lên: 24/10/2013, 19:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)

... method Qualitative analysis is made by the comparison of the retention time of a peak of a specimen with that of the authentic standard and also by the con rmation of the absence of such a peak ... be analyzed.  e amount of a conjugated form can be calculated by subtracting the amount of a free form from the total amount. By HPLC, the simultaneous analysis of free and conjugated forms ... main tool for analysis of opiates and their metabolites. However, at the present time, GC/MS is being widely used for opiate analysis. For HPLC analysis of the conjugated forms of opiates, the...

Ngày tải lên: 24/10/2013, 19:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)

... action of methemo- globin reductase (identical with cytochrome b 5 reductase requiring NADH as a cofactor) pres- ent in mammalian red cells.  e concentration of methemoglobin in blood of normal ... nitromesitylene. The concentration of nitrite was 5 µg/mL for both chromatograms. 652 Nitrate and nitrite compounds Except GC-NPD, GC-ECD can be used for analysis of nitrite and nitrate; but the ... appearance of many interfering peaks. By GC/MS in the EI mode, it is di cult to detect the derivative, because of its lower sensitivity. Although there is a report [9] dealing with sensitive GC/MS analysis...

Ngày tải lên: 24/10/2013, 19:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)

... developed a modi cation of the methods, which enabled accurate determination of blood Met-Hb even in the presence of high concentrations of CO-Hb by using about a 100-fold excess of potassium ferricynade ... Simultaneous determination of carboxyhemoglobin and methemoglo- bin in victims of carbon monoxide poisoning. J Forensic Sci 25:546–549 6) Sato K, Katsumata Y, Aoki M et al. (1981) A practical method for ... samples at freezing temperatures in the presence of a cryoprotectant for hemiglobin assay. Biochem Med Metab Biol 37:190–196 10) Sato K, Tamaki K, Tsutsumi H et al. (1990) Storage of blood for...

Ngày tải lên: 24/10/2013, 19:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)

... aliquot of it is subjected to GC/MS analysis. Cocaine and its metabolites 215 time of death nor those at the time of samplings.  erefore, there are great variation in the fatal levels of cocaine ... solvent mixture of chloroform and isopropanol or ethanol should be used.  e simultaneous analysis can be made using chloroform/isopropanol (9:1) or (3:1), and using columns of Bond Elut Certify® ... rmation of a target compound is usually achieved by agreement of its mass spectrum with that of the authentic standard. Since, with simultaneous use of a deuterated IS, a mass spectrum of a target...

Ngày tải lên: 29/10/2013, 01:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)

... 15 mg of free pentazocine.  e solution is transferred to a small glass centrifuge tube with a ground-in stopper, followed by addition of several mg of solid K 2 CO 3 and 3 mL of chloroform. ... retention times of 3–7 min and 7–8 min, respectively. The amount of pentazocine and IS spiked into 1 mL of blank whole blood or urine was equally 50 ng. ⊡ Figure 5.2 223 In two autopsy cases of pentazocine ... and GC/MS [8]. In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented. Structures of pentazocine and dextromethorphan (IS). ⊡ Figure 5.1 Reagents...

Ngày tải lên: 29/10/2013, 02:15

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

... one of the most powerful hallucinogenic drugs of abuse. LSD was explosively abused in U.S.A. in the latter half of the 1960s. In Japan, the amount of seizure of LSD is much smaller than that of ... hallucinogenic activity of LSD was con rmed by Albert Hofmann who did synthesize the compound; the pharmaco- logical activity can be obtained by oral administration of as small as 20–75 µg of LSD.  e ab- sorption ... solutions are combined. A er the pH of the solution is adjusted to 8.5, the solution is extracted with an appropriate amount of chloroform four times.  e combined chloroform extract is evaporated...

Ngày tải lên: 08/11/2013, 01:15

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