posterior segment manifestations of systemic disease pdf

... Respiratory disease usually follows the onset of bowel disease but may rarely antedate bowel symptoms 635 Imaging of the pulmonary manifestations of systemic disease Box 12: Pulmonary manifestations of ... lymphocytic infiltration of the airways causes a follicular lymphocytic 627 Imaging of the pulmonary manifestations of systemic disease Box 4: Pulmonary manifestations of Sjögren’s syndrome Airways ... presenting symptoms were of dyspnoea, dry cough, fever, and occasionally cyanosis 625 Imaging of the pulmonary manifestations of systemic disease Box 3: Pleuropulmonary manifestations of SLE Pleural x...

Ngày tải lên: 12/08/2014, 20:32

... coalescence of associated lesions and/or diseases: involvement of other hyperthyroidism, hair-bearing surfaces hypothyroidism, contact of the body vitiligo, Down syndrome Pitting of the nails ... treatment of growing (anagen) hairs simultaneously enter the dying (telogen) phase Androgeneti Miniaturizatio Increased c alopecia (male n of hairs along the sensitivity If no evidence of of hyperandrogen ... Increased levels of circulating androgens (ovarian or adrenal source in women) Alopecia areata Well- The circumscribed, Topical germinative zones anthralin; circular areas of hair of the hair follicles...

Ngày tải lên: 06/07/2014, 20:20

Ngày tải lên: 03/11/2012, 11:11

... Diseases through Blood Contact • Examples of How Some Childhood Infectious Diseases Are Spread Prevention of Infectious Disease Section Understanding the Spread of Disease Rationale: Illnesses are common ... Spread of Disease Infants and young children in child care have an increased rate of certain infectious disease and an increased risk of getting antibiotic-resistant organisms Prevention of infectious ... more than one method of control in order to reduce the transmission of infectious disease You can control the spread of communicable disease in three ways: Attack the source of infection or the...

Ngày tải lên: 12/02/2014, 12:20

Ngày tải lên: 15/02/2014, 13:20

Ngày tải lên: 15/03/2014, 12:20

... benefits of screening for coeliac disease at the time of diagnosis of diabetes The assessment took place because of the variation in practice of screening for autoantibodies associated with coeliac disease ... coeliac disease NICE clinical guideline 86 Coeliac disease 1.1.3 Consider offering serological testing for coeliac disease to children and adults with any of the following: Addison's disease ... range of symptoms before diagnosis Delayed diagnosis is a concern because the symptoms of coeliac disease remain untreated and because of the possible long-term effects of undiagnosed coeliac disease...

Ngày tải lên: 22/03/2014, 09:20

... pro-inflammatory effects of DE Subchronic DE Exposure Modifies the Pro-inflammatory Profile of the Midbrain In an effort to further address the degree of sensitivity of the midbrain to air pollution, ... Agency, U.S Department of Energy (Office of Freedom Car and Vehicle Technologies), and U.S Department of Transportation This manuscript does not represent the views or policies of any sponsor The ... the concentration of 2000 μg PM/m3 DE [18] Here, we measured the effects of lower DE levels and month exposure on brain regions: the olfactory bulb (a hypothesized point of entry of PM in the brain);...

Ngày tải lên: 19/06/2014, 22:20

... versed in the recognition of cutaneous lesions or their spectrum of presentations Therefore, the authors of this chapter have decided to cover this particular topic of cutaneous medicine not ... Parapsoriasis f Bowen's disease (squamous cell carcinoma in situ)b Drugs Systemic diseases a Lupus erythematosus c b Cutaneous T cell lymphoma c Secondary syphilis d Reiter's disease e Sarcoidosisd ... in the thickness of the lesions The diagnosis of CTCL is established by skin biopsy in which collections of atypical T lymphocytes are found in the epidermis and dermis As the disease progresses,...

Ngày tải lên: 06/07/2014, 20:20

... lag time of 48 h Systemic : Gener alized Patie nt history has testing of Erythe allergic ma, fine scale, contact crust dermatitis to topical agent and Patch Same as local then receives systemic ... migration of the erythema and associated secondary changes such as pustules or erosions Migratory waves of erythema studded with superficial pustules are seen in pustular psoriasis Table 54-2 Causes of ... Local: act Depen ds Irrita on nt—onset Patch testing Remo ve irritant or Erythe offending allergen; agent ma, often within hours topical crusting, vesicles, and glucocortico bullae Aller ids;...

Ngày tải lên: 06/07/2014, 20:20

... to 25% of the cases of erythroderma were due to CTCL The patient may progress from isolated plaques and tumors, but more commonly the erythroderma is present throughout the course of the disease ... late stage of the disease Alopecia (Table 54-4) The two major forms of alopecia are scarring and nonscarring In scarring alopecia there are associated fibrosis, inflammation, and loss of hair follicles ... cases of erythroderma where there is no apparent cause (idiopathic), longitudinal follow-up is mandatory to monitor for the possible development of CTCL There have been isolated case reports of...

Ngày tải lên: 06/07/2014, 20:20

... the scarring lesions of discoid lupus can be seen in patients with systemic lupus, in the majority of cases the disease process is limited to the skin Less common causes of scarring alopecia ... the result of a primary cutaneous disorder such as lichen planus, folliculitis decalvans, chroniccutaneous (discoid) lupus, or linear scleroderma (morphea) than it is a sign of systemic disease ... Scattered, poorly circumscribed patches of alopecia with a "moth-eaten" appearance are a manifestation of the secondary stage of syphilis Diffuse thinning of the hair is also associated with hypothyroidism...

Ngày tải lên: 06/07/2014, 20:20

... acne rosacea, the two major forms of acne (Chap 53), there are drugs and systemic diseases that can lead to acneiform eruptions (Table 54-7) Table 54-7 Causes of Acneiform Eruptions I Primary ... Behçet's disease a EGFR, epidermal growth factor receptor Patients with the carcinoid syndrome have episodes of flushing of the head, neck, and sometimes the trunk Resultant skin changes of the ... lithium Administration of highdose systemic glucocorticoids can result in a widespread eruption of follicular pustules on the trunk, characterized by lesions in the same stage of development With...

Ngày tải lên: 06/07/2014, 20:20

... Ionizing radiationa Poikiloderma vasculare atrophicans C Spider angioma Idiopathic Pregnancy II Systemic diseases A Linear Carcinoid Ataxia-telangiectasia Mastocytosis B Poikiloderma Dermatomyositis ... Table 54-8 Causes of Telangiectasias I Primary cutaneous disorders A Linear Acne rosacea Actinically damaged skin...

Ngày tải lên: 06/07/2014, 20:20

... variant of scleroderma (Chap 316) is associated with a chronic course and anticentromere antibodies Mat telangiectasias are an important clue to the diagnosis of the CREST syndrome as well as systemic ... pathognomonic signs of the three major autoimmune connective tissue diseases—lupus erythematosus, scleroderma, and DM They are easily visualized by the naked eye and occur in at least two-thirds of these ... eccentric punctum with radiating legs is seen Although the degree of systemic involvement varies in this autosomal dominant disease (due to mutations in either the endoglin or activin receptor–like...

Ngày tải lên: 06/07/2014, 20:20

... perifollicular macules of normal pigmentation are seen within areas of depigmentation The basis of this leukoderma is unknown; there is no evidence of inflammation in areas of involvement, but it ... (types I and II) Diseases of the thyroid gland are the most frequently associated disorders, occurring in up to 30% of patients with vitiligo Circulating autoantibodies are often found, and the ... absence of pigmentation Patients with vitiligo also have an increased incidence of several autoimmune disorders, including hypothyroidism, Graves' disease, pernicious anemia, Addison's disease, ...

Ngày tải lên: 06/07/2014, 20:20

... the result of the migration of two clones of primordial melanocytes, each with a different pigment potential Localized areas of decreased pigmentation are commonly seen as a result of cutaneous ... lesions, but in one rare clinical setting they are a sign of systemic disease, and that setting is the sudden appearance of multiple lesions, often with an inflammatory base and in association with ... Drugs II Systemic diseases A Localized Epidermal alteration a Seborrheic keratoses (sign of Leser-Trélat) b Acanthosis nigricans (endocrine disorders, paraneoplastic) Proliferation of melanocytes...

Ngày tải lên: 06/07/2014, 20:20

... (cryptorchidism, hypospadias); retardation of growth; and deafness (sensorineural)] syndromes, lentigines serve as a clue to systemic disease In LEOPARD syndrome, hundreds of lentigines develop during childhood ... location as circular areas of erythema that can become bullous and then resolve as brown macules The eruption usually appears within hours of administration of the offending agent, and common ... leukoplakia of the oral and anal mucosae The latter often develops into squamous cell carcinoma In addition to the flagellate pigmentation (linear streaks) on the trunk, patients receiving bleomycin often...

Ngày tải lên: 06/07/2014, 20:20

... widespread deposition of melanin resulting from the high concentration of circulating melanin precursors, there is more evidence to support the latter Of the autoimmune diseases associated with ... drugs or metals can result from one of several mechanisms—induction of melanin pigment formation, complexing of the drug or its metabolites to melanin, and deposits of the drug in the dermis Busulfan, ... level of iron in the skin of patients with hemochromatosis stimulates melanin pigment production and leads to the classic bronze color Patients with pellagra have a brown discoloration of the...

Ngày tải lên: 06/07/2014, 20:20

... simplex virusa,e Enteroviruses, e.g., hand-foot-and-mouth disease Staphylococcal scalded-skin syndromea,f Bullous impetigoa II Systemic diseases A Autoimmune Paraneoplastic pemphigusa B Infections ... Pseudoporphyriab Bullous dermatosis of hemodialysisb D Ischemia Coma bullae a Intraepidermal b Subepidermal c Associated with gluten enteropathy d Associated with inflammatory bowel disease ... herpetiformisb,c Linear IgA bullous dermatosisb Epidermolysis bullosa acquisitab,d B Secondary blistering diseases Contact dermatitisa Erythema multiformea,b Stevens-Johnson syndrome Toxic epidermal necrolysisb...

Ngày tải lên: 06/07/2014, 20:20