possible pathway for the invasion of alien species
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
Ngày tải lên :
19/02/2014, 06:20
... To address the question of whether hypoxia influences the promoter activity of the human HO-1 or HO-2 gene, we performed transient expression assays Prior to the functional analysis of the HO-2 ... required to address the role of heme degradation in the population of hemoglobin-positive cells To the best of our knowledge, there has been no report on the promoter function of the human HO-2 FEBS ... head-to-head orientation, and their transcription start sites are 1.5 kb apart We therefore analyzed the promoter function of the 1.5 kb 5¢-flanking region of the HO-2 gene in the present study YN-1...
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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx
Ngày tải lên :
17/03/2014, 10:20
... content of 48.0% [43] The GC content of the region essential for the biosynthesis of SPA in the other serotype strains (b–e) of A actinomycetemcomitans is also lower than the average GC content of these ... in the clusters responsible for synthesizing the SPAs in other serotypes of A actinomycetemcomitans The biosynthetic pathway for GDP-6-deoxy-D-talose, Ó FEBS 2002 GDP-6-deoxy-D-talose synthetic ... involving the gmd gene products halted after consuming some of the GDP-a-D-mannose, regardless of the addition of the proteins The peak that appeared at 24.0 was in agreement with that of authentic...
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Báo cáo y học: "Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients" pps
Ngày tải lên :
13/08/2014, 16:21
... 14 distinct signaling pathways, including the NF-κB pathway Interestingly, many of the genes in these pathways are regulated by the proteasome [18] Therefore, combined with our results, this may ... to the cytoplasmic domain of the receptor [10] Subsequently, TRAF6 interacts with UBC13/UEV1A, a heterodimer that catalyzes the synthesis of polyubiquitin chains assembled through linkage of the ... survey the activity of NF-κB at the level of the whole organism in Velcade treated and untreated animals Optimally, one would like to know how the NF-κB pathway functions in any tissue of interest...
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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
Ngày tải lên :
19/02/2014, 16:20
... Enlargement of the original plots shown in (B) present in cell extracts of succinate/glucose-grown cells; therefore, the synthesis of the enzyme was inducible Table shows a summary of a typical ... and the determination of released ammonia The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabolism, including the deamination step The product formed ... The decarboxylation mechanism in the metabolic pathways for 3-hydroxyanthralinic acid differs from that in the pathway for 4-amino3-hydroxybenzoic acid The N-terminal amino acid sequence of the...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
Ngày tải lên :
22/02/2014, 04:20
... M/F at the as1-Cas locus Therefore, analysis of their transcripts could have been rather difficult because of the occurrence of at least nine different forms of messenger arising from the F allele ... indicate the position of the introns The boxes indicate amino-acid substitutions skipping of three successive exons during the course of the processing of the primary transcripts [9] At the peptide ... wonder whether the donor allele of the 5¢ part is the F allele or another allele belonging to the same B allelic lineage (excluding B1 and C), as they share the same simplified haplotype formula,...
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Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx
Ngày tải lên :
23/03/2014, 13:20
... (Invitrogen), and the isolation of RNA followed the manufacture’s protocol The synthesis of first-strand cDNA was performed using the Superscript preamplification system (Invitrogen) Either lg of total ... characteristic of 7-DHP (Fig 5) The H-NMR spectrum of the biotransformation product is in agreement with that of the chemically synthesized standard (Fig 5) and with data from the literature [41] Thus, the ... product of 7-DHC transformation (C) Differing from these reaction products were the parameters for the 7-DHC; the retention time for its ion with m/z 385.3 and UV spectra are shown in the inset...
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Báo cáo Y học: Modeling the three-dimensional structure of H+-ATPase of Neurospora crassa Proposal for a proton pathway from the analysis of internal cavities pptx
Ngày tải lên :
23/03/2014, 21:20
... rather on the regions initiating or impairing insertion of a segment in the membrane Therefore, in the case of M8 where the length of the M8 recombinant peptide is probably shorter than that of ... envelope of the enzymes Cavities are colored by atom type (red stands for O, blue for N and yellow for S) The backbone position of the ten polar residues lining the proton pathway and contacting the ... outside the surface envelope of the enzymes Cavities are colored by atom type (red stands for O, blue for N and yellow for S) beginning of the transmembrane domain The presence of this string of polar...
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Báo cáo lâm nghiệp: "Assessing the potential of natural woody species regeneration for the conversion of Norway spruce plantations on alluvial soils" doc
Ngày tải lên :
08/08/2014, 01:22
... out first for these two species separately and then on the pooled other species (vi) To investigate the spatial distribution of the woody species regeneration in each site, the Morisita index (I) ... of saplings for the different clusters are shown in Figure A particular characteristic of the Norway spruce plantations was the presence of few (1–3) dominant tree species in composition of the ... abundance of the total numbers of tree seedlings and saplings often reflected variations of these dominant species Table I Influences of regional and local environmental factors on the types of Norway...
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Báo cáo y học: "Ulysses - an application for the projection of molecular interactions across species" pdf
Ngày tải lên :
14/08/2014, 15:20
... display species- specific protein networks allows the user to trace back the origin of the projected data; the user can assess projections based on the source of evidence The user can further choose ... as the secondary interactions to the direct partners of the reference gene These primary and secondary interactors are plotted and displayed in a series of network windows for each species The ... was true for between 75% and 97%, depending on the species and method (Table 4) Compared to the background rate of 66% for the randomly generated pairs of interactors (which reflects the fact...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
Ngày tải lên :
25/10/2012, 10:45
... on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the VA population Moreover, we might expect that the PPV and NPV of the ... NC) Results The characteristics of the VARA participants measured at the start of each treatment episode were evaluated Because the characteristics of VARA patients at the start of non-biologic ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic...
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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
Ngày tải lên :
25/10/2012, 11:40
... attempted for three SPT patients in whom the mass was located in the portion of body or tail of the pancreas For tumors of SPT located in the neck and body of the pancreas, resection of the midportion ... midportion of the pancreas and the mass with preserving the rim of the head and tail portion can be achieved However, for the patient in whom the mass was located within the head of the pancreas, ... 311 Fig The CT scan indicated the typical internal or capsular calcification in the SPT Once the diagnosis of SPT is made, surgery is the first choice of treatment, since other adjuvant therapies,...
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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique
Ngày tải lên :
26/10/2012, 09:32
... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... that the direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the...
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Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"
Ngày tải lên :
26/10/2012, 09:57
... laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the current ... and neural structures increases the risk of adverse events with invasive approaches Open surgical correction is the current standard of care for foraminal stenosis of cervical and lumbar vertebrae ... follow-up Results The author acknowledges that there are no conflicts of interest or financial benefits with the results of the study All twelve patients (10 males, females) completed the surgery without...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
Ngày tải lên :
26/10/2012, 10:04
... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences ... IC50 values of 30 µM for hSGLT1 and 10 µM for hSGLT2, while thioglycoside VII showed IC50 values of 15 µM for hSGLT1 and 88 µM for hSGLT2 These data confirm the strong inhibitory effects of thioglycoside...
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Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)
Ngày tải lên :
03/11/2012, 10:58
... large inventory of normalized mathematical indexes of abnormality It is the pattern of these mathematical indexes of abnormality, obtained from analysis of multiple cardiac cycles of the resting ... Moreover, to assess the performance of the prediction of stenosis independent of the prevalence of stenosis, the positive and negative likelihood ratios (LR) were calculated [24] A value of p
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A research proposal submitted in partial fulfillment of the requirements for the degree of Master of Business Administration
Ngày tải lên :
13/04/2013, 10:30
... with the supermarkets Along with the actual evaluations of the stores’ performance, the research tries to uncover the shoppers’ expectations of this kind of store In addition, the demographic profile ... level of 90% (app.D, p 84-86) 4.1.10 Demographic profile of supermarkets’ non-users and heavy-users The demographic profile of heavy users in the sample is similar to the profile described for the ... of the store by evaluating the store in terms of the factors comprising the choice criteria Based on the evaluation, the consumer 18 forms a degree of preference for the store If preference exceeds...
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SOME SOLUTIONS FOR THE DEVELOPMENT OF CONSUMER LENDING AT TECHCOMBANK HOANG QUOC VIET
Ngày tải lên :
25/07/2013, 11:20
... Step 3: The director of the branch will responsible for approving the loan application form or not if the value of the loan does not exceed 500 million In case of an exceed, the director of the branch ... expanded the scope and form of lending to customers The orientation of the branch: expanding, strengthening and improving the operational efficiency of the office agency To attract more customers, the ... actually the major activity of the bank Therefore, continuing research and offering solutions would bring enormous significance for both theoretical and practical aspects for the diversification of the...
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Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens
Ngày tải lên :
05/09/2013, 08:40
... supported by the research project The research on the development of the total evaluation technique for the hazardous impacts by the chemical substances towards human and ecology (the project ... and N2- and C8-modified deoxyguanosine as major products of the in vivo reaction of N-hydroxy-6-aminochrysene with DNA and the formation of the adducts in isolated rat hepatocytes treated with 6-nitrochrysene, ... postlabeling method, etc.) Therefore, it is important to develop a simple rapid in vitro method for evaluating the generation of reactive oxygen species from a variety of genotoxic chemicals We...
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Application of Ozone/UV Process for the Reclamation of Sewage Treatment Plant Effluent
Ngày tải lên :
05/09/2013, 08:40
... study, the ozone and UV combination (ozone/UV) process is applied for the reuse of sewage effluent Therefore, the aim of this study is to evaluate the effectiveness of ozone/UV process for the treatment ... the mechanism of the reaction of ozone with substances in the water can be divided into two distinct pathways (7) The first route is the direct attack of molecular ozone The second route is the ... reduction of A410 after 10 of run time On the other hand, the UV alone process did not show much color change Therefore, for color reduction, the ozone alone process was considered as the best...
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