polymeric systems for oral protein and peptide delivery

... promising candidates as chemical and/ or protein drug carriers to materialize sustained drug delivery systems Although promising results have been achieved with chemical drug delivery systems, inadequate ... loading, releasing, and stability issues remain critical impedimenta for sustained protein delivery systems To address these obstacles, a new type of pH- and temperature-sensitive polymeric hydrogel ... allow for a predictable and customizable loading and release In this study, the challenger of molecular design of novel pH and temperature-sensitive hydrogels is polymer and drug (special for ionic...

Ngày tải lên: 13/05/2016, 10:14

... and protein and peptide separation for N-terminal sequence analyses It is important to remember that all forms of SDS-PAGE are denaturing, and are therefore unsuitable for separation of proteins ... &IAP!FER The Bradford Method for Protein Quantitation Nicholas J Buger Introduction A rapid and accurate method for the estimation of protein concentration is essential in many fields of protein study ... most convenient and widely used formulation Two types of assay are described here: the standard assay, which is suitable for measuring between lo-100 B protein, and the microassay for detecting...

Ngày tải lên: 10/04/2014, 11:03

... to ion formation m the electrospray process, Mickey, unfortunately, died in May 1991, and therefore did not get the chance to see how his dream about the role of MS m protein studies and hts ... used m protein chemistry m terms of senstttvtty and acceptance of solvents, detergents, and buffers, They must be able to handle impure samples and complex mixtures Last, but not least, the information ... (ACTH) l-14 and a-endorphtn, respectively The former peptide has a mrdchain argmine, and the latter has no arginme residue TMAA derivative spectra of these peptides are shown m Figs 1B and 2B, respectively...

Ngày tải lên: 11/04/2014, 10:11

... test weights for each sport 12 Expert Systems for Human, Materials and Automation Knowledge engineering, forming of the knowledge base and coding of the stand-alone application lasted for about ... in preformulation and formulation studies of medicines specifically in solid dosage forms This system informs on the physical profile of powdered substances (APIs and excipients) used to formulate ... such systems Such understanding has already benefited our society though increased life expectancy and quality, improved and cost effective health care and prevention Engineers have looked for...

Ngày tải lên: 19/06/2014, 10:20

... IGC 28 Expert Systems for Human, Materials and Automation Table Radius parameters, mean incidence and parametric index for excipients DC 29 SeDeM Diagram: A New Expert System for the Formulation ... maximum amount required for a comprehensive understanding of the proposed formula From this first formulation, research can get underway for the final optimization of the formulation, taking into ... SeDeM Diagram: A New Expert System for the Formulation of Drugs in Solid Form 33 Conclusions Here we developed an original methodology for the preformulation and powder substance characterization...

Ngày tải lên: 19/06/2014, 10:20

... statement and searching and formulating the answers on them QA-modeling helps to combine questions and answers in QA-model of the task and its parts and for checking them on the correctness and conformity ... create and use the icon for the necessary types or subtypes for Z-, Q- and A-objects QA-variables can be qualified as a definite type of Q- and A-objects For this type the icons for letters D and ... pseudo-code programs for different tasks As for QA-variables the special icons for letters „O“ (for operator) and „E“ (is executed) have been created and used instead icons for letters „Q“ and „A“ The...

Ngày tải lên: 19/06/2014, 10:20

... energy, and finance 110 Expert Systems for Human, Materials and Automation As a result of advances in natural and biological sciences, current engineering systems, subsystems, components and platforms ... language text, maps, tables, menus, and forms It can also handle input through several modes - menus, forms, and pointing 98 Expert Systems for Human, Materials and Automation Both the use of multi-modal ... cells combine to form tissues (e.g skin tissues, muscle tissues, bone tissues), tissues combine and form organs, organs combine to form organ systems, and organ systems combine to form the human...

Ngày tải lên: 19/06/2014, 10:20

... Expert Systems for Human, Materials and Automation 2.2.3 Health prognostics (HP) The word prognostic is taken from the Greek Prognostikos (of knowledge beforehand) It combines pro (before) and gnosis ... Structural health monitoring (SHM) SHM stands principally for structural health monitoring It also stands for structural health management, systems health monitoring and systems health management It must ... analysis and transmission These highly networked sensors (passive or active) are suitable for large and complex platforms and wide area monitoring and exploit recent development in micro and nano...

Ngày tải lên: 19/06/2014, 10:20

... knowledge and addition of new ones into knowledge base 166 Expert Systems for Human, Materials and Automation The first two components form the so-called knowledge base Representation and organization ... Hardening and strain rate parameters β , C and p 2.4 Geometry of the dies and the blank Finally, it is necessary to decide how to generate the geometry of the dies and the blank The forming tools ... users for this application (the ones that are used to employ finite elements applications, and the ones that are not), two options have been implemented: 146 Expert Systems for Human, Materials and...

Ngày tải lên: 19/06/2014, 10:20

... iron and steel industry, Ironmaking and Steelmaking, 2004, vol 31, No.6 Friedmann E.– Hiu, Jess the Rule Engine for the Java Platform, CA, USA 2003 Han J and M.Kamber: Data Mining:Concepts and ... transmitter and the ground (i.e this corresponds to the height of the tank), t1 and t2, the transit time of the first and second echoes respectively, and v1 and v2 the speed of microwaves in the air and ... 1995 to 2004,Expert Systems with Applications 28(2005),93-103 180 Expert Systems for Human, Materials and Automation Singh A., et al Predicting microstructural evolution and yield strength of...

Ngày tải lên: 19/06/2014, 10:20

... deterioration and other problems in reinforced concrete structures is indeed huge and enormously wide and of great interest to civil engineers There are standards for the use of reinforced concrete ... with a specific color (e.g Blue for water, pink for emulsion, yellow for gas, and brown for crude oil) Fig 28 Dynamic tracking of sensor 16 in water-dominant (a) and oil dominant (b) emulsion Interface ... designed, implemented and tested for realtime and accurate detection of the emulsion layer in a 4.35 m height tank In addition, it was 208 Expert Systems for Human, Materials and Automation demonstrated...

Ngày tải lên: 19/06/2014, 10:20

... creates the necessity to employ intelligent systems, due to the demand of a better performance and resolution of complex problems both for men as well as for the machines Gradually the time restrictions ... but for the implementation of the PID regulator used, defined in the previous formula and more commonly known as the Standard format Astrom & Hagglund (2006) Feng & Tan (1998), shown in the form ... itself and the specifications 254 16 Expert Systems for Human, Materials and Automation Will-be-set-by-IN-TECH Fig 17 Systems of Benchmark ordered from lower to higher L/T value Fig 18 Systems...

Ngày tải lên: 19/06/2014, 10:20

... description and a base price of standard using the exact - in the later stages of the design is based on information from a comparison of measurement and control equipment and bills of materials and ... propulsion, power, and the following marine systems 264 Expert Systems for Human, Materials and Automation (installation): fuel, lube oil, fresh water, sea water, compressed air, boiler and steam system, ... carried out for example the number of cycles in the 100 - 30000, 50000 and even at the values of coefficients η1 and η2 equal 0.9 and 0.6 respectively and the values in the range - 0.1 and – In...

Ngày tải lên: 19/06/2014, 10:20

... system hardware and software components, whose parameters must be maintained and updated on regular basis 302 Expert Systems for Human, Materials and Automation On the other hand, performance management ... requires the ability to monitor devices, systems and network traffic for performance problems, and to take control and appropriately respond to them before they affect network availability Optimization ... 15min with the results in the form of Degrees of Evidence and classification of the tenor of sea pollution 298 Expert Systems for Human, Materials and Automation outstanding in these conditions...

Ngày tải lên: 19/06/2014, 10:20

... Energization Quantity V+ and I+ or I+ V+ De-energization and or Isolated unit and Synchronism and Normal operation Out of service and Forced shutdown and Load increment and Load decrement and or or I+ P ... > 0.9pu and I1m > 0.05pu and Disturb = “normal” V1m > 0.9pu and I1m < 0.05pu and Disturb = “normal” V1m < 0.1pu and I1m < 0.05pu and Disturb = “normal” 0.1 0.05pu and ModV12 < 0.2pu and Disturb = “unbalanced” V0 > 0.05pu and −0.1

Ngày tải lên: 19/06/2014, 10:20

... system for wireless ad hoc network They use fuzzy set theory for best-effort traffic regulation, and propose 354 Expert Systems for Human, Materials and Automation Expert Systems schemes for real-time ... quality of service of WLAN systems and the simulations and results were performed for the IEEE 802.11b system, the approach and the techniques are not limited to these systems, but are easily applicable ... cost, format, performance, synchronization and user classes Cost parameters include costs of connection and data transfer Compression, frame rate, and resolution are format parameters Bit rate and...

Ngày tải lên: 19/06/2014, 10:20

... are run(step in Fig 4) For new scenarios, it is necessary to repeat steps and on Fig 386 Expert Systems for Human, Materials and Automation Expert system for analyzing performances of tactical ... report files The first is for detailed analysis using Tactical player, and the second one is user readable, which contains information about network performance and directions for network improvements ... Telecommunications and Computer Networks (SoftCOM), Split Krishnamoorthy, C S., & Rajeev, S (1996) Artificial Intelligence and Expert Systems for Engineers Liebowitz, J (2004) The Handbook of Aplied Expert Systems...

Ngày tải lên: 19/06/2014, 10:20

... Agroforestry Systems Outputs and Performance indicators Outputs ♦ The enhancement of training/extension and research services on agroforestry systems for sustainable livestock production for ... significant cash income for concentrate feeds are most July 2002 CARD Vietnam – Agroforestry Systems Implementation Performance 3.1 Project Components and Outputs Compone Performance Perform' Component ... centre of the National Institute for Animal Husbandry) and Dr Ha Huy Thinh of the Research Centre for Forest Tree Improvement (RCFTI) (a research centre of the Forest Science Institute of Vietnam)...

Ngày tải lên: 22/06/2014, 13:20

... system) and consisted of seven (11%) systems for geriatric patients [17,23,25, 35,37,42,65], three (5%) systems for paediatrics [32,43,73], four (6%) systems for women’s health [36,40,70,71], and ... Recommendations for diagnosis and management of hypertension, diabetes mellitus, and dyslipidaemia in primary care For hypertension and diabetic patients, change at 21 months in systolic and diastolic ... guidelines for use of aspirin, oestrogen or calcium, ACEIs, heparin prophylaxis, and b-blockers Alerts for drug allergies 6*/276/5,219 and drug-drug interactions, and options for cost-effective...

Ngày tải lên: 10/08/2014, 11:20

... help and support I thank all my co-workers for the pleasant working atmosphere I also wish to thank Markku Koskinen and Esa Jansson from Noptel and Ilkka Kaisto from Prometrics for their help and ... help and for the sincere interest they showed towards my work I wish to thank Prof Erkki Ikonen and Dr Kalevi Hyyppä for examining my thesis, and Mr Malcolm Hicks and Mr Janne Rissanen for revising ... DEVICES AND SENSOR SYSTEMS FOR OPTICAL TRACKING AND DISPLACEMENT SENSING APPLICATIONS Academic Dissertation to be presented with the assent of the Faculty of Technology, University of Oulu, for public...

Ngày tải lên: 03/10/2014, 22:39