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poly alkyl cyanoacrylate nanoparticles for drug delivery and vaccine development

Controlled release alginate based microparticulate systems for drug delivery and chemoembolization

Controlled release alginate based microparticulate systems for drug delivery and chemoembolization

Cao đẳng - Đại học

... contraceptive hormones and lipophilic drugs (Le and Tsourounis, 2001) Polyurethane, another non-biodegradable polymer, is useful as a carrier for peptide and protein drugs (Zdrahala and Zdrahala, 1999) ... synthetic polymers attractive and preferred choices for the formulation of controlled release DDS especially if they are for the oral route Poly( anhydrides), poly( amino acids), poly( esters), poly( orthoesters), ... These polymers were initially developed to be used as suture materials (Shive and Anderson, 1997) Poly( lactide) (PLA) can exist in the form of poly( L-lactide) (PLLA), poly( D-lactide) (PDLA) and poly( D,L-lactide)...
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Wheat germ agglutinin conjugated poly dl lactic co glycolic acid (PLGA) nanoparticles for enhanced uptake and retention of paclitaxel by colon cancer cells

Wheat germ agglutinin conjugated poly dl lactic co glycolic acid (PLGA) nanoparticles for enhanced uptake and retention of paclitaxel by colon cancer cells

Cao đẳng - Đại học

... capability Polymers employed for nanoparticle fabrication have included synthetic polymers, such as Poly (D, L-lactic-co-glycolic acid) (PLGA), polyacrylates and polycaprolactones, and natural polymers ... material and a scaffold for tissue engineering, but also in drug delivery (Ignatius & Claes, 1996; Day et al., 2005) PLGA delivery platforms have been developed for the sustained and targeted delivery ... (usually metallic) and a protective organic surface coating Organic nanoparticles include liposomes and other lipid-based carriers, polymeric nanoparticles, micelles and various ligand-targeted products...
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Design and fabrication of microneedles for drug delivery

Design and fabrication of microneedles for drug delivery

Cao đẳng - Đại học

... are designed for transdermal therapies to deliver drugs such as insulin and heparin On the other hand, microneedles can also be used for local delivery of other drugs, for example, drugs in anti-restenosis ... varying delivery of different therapeutics, which is essential for a more effective drug delivery system The direct delivery of DNA/portent based drugs into the metabolic system and the continuous delivery ... staying there for me and watching over me I also would like to thank my parents and the rest of my family, for their understanding and continual support I would like to thank my mum and dad for their...
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In vitro and in vivo evaluation of transferrin conjugated lipid shell and polymer core nanoparticles for targeted delivery of docetaxel

In vitro and in vivo evaluation of transferrin conjugated lipid shell and polymer core nanoparticles for targeted delivery of docetaxel

Tổng hợp

... are typically used as drug delivery system (Peer et al 2007) The most common drug delivery systems such as liposomes, polymeric nanoparticles, polymer -drug conjugates and polymeric micelles are ... 2010) Polymeric nanoparticles are generally synthesized from biodegradable polymers - like the poly (lactic acid) (PLA) and poly( lactic-co-glycolic acid) (PLGA) polyesters or the poly( alkylcyanoacrylates) ... literature review on cancer and cancer chemotherapy, and the concept and formulations of drug delivery system is provided The strategies applied for targeted drug delivery system is also clearly...
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nanoparticle technology for drug delivery, 2006, p.427

nanoparticle technology for drug delivery, 2006, p.427

Vật lý

... discussed in Chapter for injectable delivery, Chapter for oral delivery, Chapter 10 for brain delivery, Chapter 11 for ocular delivery, and Chapter 12 for gene delivery Finally, the fourth section ... T Rhodes 122 Surfactants and Polymers in Drug Delivery, Martin Malmsten 123 Transdermal Drug Delivery: Second Edition, Revised and Expanded, edited by Richard H Guy and Jonathan Hadgraft 124 ... Principles and Practices, Jens T Carstensen 44 Pharmaceutical Statistics: Practical and Clinical Applications, Second Edition, Revised and Expanded, Sanford Bolton 45 Biodegradable Polymers as Drug Delivery...
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Báo cáo hóa học:

Báo cáo hóa học: "Single-component Polymer Nanocapsules for Drug Delivery Application" docx

Hóa học - Dầu khí

... polyelectrolytes [polyallylamine hydrochloride (PAH)], polypeptides [poly- L-lysine (PLL), and poly- L-glutamic acid (PGA)], and polypeptide -drug conjugates [PGA-Doxorubicin (Dox)] The researchers ... thick-walled polymer nanocapsules for tumor therapy via drug delivery They prepared drug- loaded polymer nanocapsules according to the outlined approach by preconjugating a model anticancer drug (Dox) ... crosslinking of the infiltrated polymer chains (step 2) and subsequent removal of the SC/MS silica template (step 3), leading to thick-walled polyelectrolyte or drug- conjugated polymer nanocapsules disulfide),...
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Báo cáo y học:

Báo cáo y học: "Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice" doc

Báo cáo khoa học

... NB and CAS helped to perform the experiments, design the study and draft the manuscript GP, P-AG, CG and ED helped to design the study, participated in the analysis and interpretation of data and ... helped to perform the experiments and design the study, participated in the analysis and interpretation of data and helped to draft and critically review the manuscript All authors read and approved ... investigated magnetically retainable drug delivery systems, an approach as yet clinically unexploited despite the intense need for the development of novel i-a delivery modalities Thus, our aim...
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báo cáo khoa học:

báo cáo khoa học: "Computerized clinical decision support systems for drug prescribing and management: A decision-maker-researcher partnership systematic review" pot

Báo cáo khoa học

... Reminders for prescribing of antibiotics and drugs for asthma, COPD, and dyslipidaemia 23*/53/3,496 Sum scores for appropriate prescribing of antibiotics, statins, cholesterollowering drugs or drugs for ... guidelines for use of aspirin, oestrogen or calcium, ACEIs, heparin prophylaxis, and b-blockers Alerts for drug allergies 6*/276/5,219 and drug- drug interactions, and options for cost-effective ... Recommendations for monitoring and treatment of asthma and COPD in primary care 32*/40/ 156,772 Number of prescriptions for respiratory drugs Lester, 2006 [45,59] Recommendations for the management...
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báo cáo khoa học:

báo cáo khoa học: " Assisted injection in outdoor venues: an observational study of risks and implications for service delivery and harm reduction programming" pps

Báo cáo khoa học

... Network of Drug Users (VANDU), a drug- user led organization, formed the Injection Support Team (IST) The IST responds to the unique needs of this population by providing peer-based education and support ... provided written informed consent At baseline and semi-annually, participants complete an interviewer-administered questionnaire, which elicits demographic data, and information regarding drug use, injection ... injectors and individuals who require assistance with injection for CIRI care [25,26] Importantly, drug user led organizations have been emerging globally and have demonstrated that drug users...
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Báo cáo y học:

Báo cáo y học: "A tumor cord model for Doxorubicin delivery and dose optimization in solid tumors Steffen Eikenberry" ppsx

Báo cáo khoa học

... plasma drug bound to albumin The flux of bound drug is similarly a function of θδS and B There are two versions for all transport parameters, one for free DOX (typically subscripted by F) and one for ... depends on both F and B, but only free drug is actually transported, and μ and υ only appear in the equation for F Transport across cell membranes at a given spatial point depends upon drug concentration ... vessel and tumor tissue The osmotic reflection coefficient for albumin, σ, is between and in most tissues, and approaches in skeletal muscle and the brain [21] Page of 20 (page number not for citation...
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Particle development for drug delivery

Particle development for drug delivery

Cao đẳng - Đại học

... classes of drugs For Class I and III drugs, the high solubility will mean that the rate of drug appearance in the blood is determined by the absorption rate of the drug whereas for Class II drugs, ... for providing the postgraduate research scholarship My thanks go to Teresa, Mei Yin, Celine, Tin Wui and Charlene for their technical assistance, and to Professor Lucy Wan and Dr Anthony Yolande, ... 3, ao, an and bn are the zeroth and nth order Fourier coefficients containing information on the particle size and shape (Ehrlich and Weinberg, 1970) Thus, Equation contains all the information...
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Tài liệu ITIL® V3 and ASL Sound Guidance for Application Management and Application Development docx

Tài liệu ITIL® V3 and ASL Sound Guidance for Application Management and Application Development docx

Cao đẳng - Đại học

... provide guidance and understanding about the synergy and distinctness of each framework This publication explains how both ITIL v3 and ASL define and address the Applications domain and provide the ... provide guidance and understanding about the synergy and distinctness of each framework This publication explains how both ITIL V3 and ASL define and address the Applications domain and provide the ... applications and therefore actually modifies the source code, then ASL provides additional and necessary guidance ASL and ITIL use the terms Application Management and Application Development...
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Review of the challenges and opportunities for rural infrastructure and agroindustries development in the Asia Pacific Region. pdf

Review of the challenges and opportunities for rural infrastructure and agroindustries development in the Asia Pacific Region. pdf

Quản lý nhà nước

... financing for research and infrastructure; Pre-andPost graduate studies scholarships; Commercial protection and foreign investment regulation; Private and public sector purchases and investment, and ... understanding and lack of professional management skills in the workforce restricts innovation and consistent performance The physical working environment for many agro industries can be demanding and ... Total Land Area Land Use Distribution (in %) Ratio of Agricultural Land to Agricultural Population 2004 Unit: ha/caput Arable & Permanent Crops Land Permanent Pasture Forests & Woorland Other Land...
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báo cáo khoa học:

báo cáo khoa học: " The first set of EST resource for gene discovery and marker development in pigeonpea (Cajanus cajan L.)" ppsx

Báo cáo khoa học

... sec at 72°C; and 20 at 72°C for final extension PCR products were separated on 6% nondenaturing polyacrylamide gels for h at 600 V and visualized by silver staining The polymorphism information ... of other classes were found For instance, di- and tri- nucleotide SSRs accounted for 40 (1.1%) and 33 (0.9%) respectively On the other hand, tetrameric, pentameric and hexameric microsatellites ... methods, and SSR development from ESTs has been successful in EST data mining [22,23,53-56] SSR motifs with repeats more than eight for di-nucleotides, six for tri-nucleotides, and five for tetra-nucleotides...
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báo cáo khoa học:

báo cáo khoa học: " ESTs from a wild Arachis species for gene discovery and marker development" pdf

Báo cáo khoa học

... not for citation purposes) BMC Plant Biology 2007, 7:7 were polymorphic for the AA population, and four for cultivated peanut Primer sequences, microsatellite types, polymorphism, homologies and ... Embrapa Genetic Resources and Biotechnology Germplasm Bank Markers polymorphic for the diploid population were genotyped and map positions determined For screening for polymorphism in the cultivated ... comparisons and functional categorization of 8,785 randomly collected cDNA clones of A stenosperma and their use for the development of 107 microsatellite markers These data will be useful for those...
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broadband as a platform for economic, social and cultural development - lessons from asia - bb as a platform, oecd, 19 nov

broadband as a platform for economic, social and cultural development - lessons from asia - bb as a platform, oecd, 19 nov

Ngân hàng - Tín dụng

... greater with broadband;4 Broadband is credited with boosting e-commerce sales, for instance for sales of movies both for online delivery and for online ordering;5 Mobile broadband can improve business ... broadband to “cannibalize” other services, for instance by substituting downloaded video-on-demand for live TV shows, or substituting voice over broadband for regular telephone service Broadband’s ... on demand services, such as YouTube) and in the business field (e.g the facilitation of e-commerce); The access that broadband provides to global markets, for instance for outsourcing, and for...
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Establishing improved platforms for dengue diagnosis and hybridoma development using dengue virus envelope domain III antigen a

Establishing improved platforms for dengue diagnosis and hybridoma development using dengue virus envelope domain III antigen a

Cao đẳng - Đại học

... wife, Lydia, and my son, Benjamin (whose name means „Son of my right hand‟) Your presence alone is a constant joy and support for me I thank Jesus for his great abundance of love, wisdom and grace ... platform …………………… …… … 160 RESULTS ESTABLISING IMPROVED PLATFORMS FOR HYBRIDOMA DEVELOPMENT 5.1 Establishing improved platforms for hybridoma development ………………………………………… … 163 5.2 Determining the ... Currently, there is a need for the production of cost effective and safe rDIII protein-related biologics for the development of protein subunit vaccines or diagnostic reagents For these purposes, the...
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Establishing improved platforms for dengue diagnosis and hybridoma development using dengue virus envelope domain III antigen b

Establishing improved platforms for dengue diagnosis and hybridoma development using dengue virus envelope domain III antigen b

Cao đẳng - Đại học

... expression Table DIII forward and reverse primers used for PCR amplification of DIII DNA sequences DIII forward and reverse primers Primer sequences Amino acid coordinates DENV1_forward CTA GCT AGC ... rDIII purification was performed and WP was found to be consistently good for the purification of WNV(NY, W and K) rDIII proteins (Fig 3E, G and H) Factors such as protein yield and purity were taken ... popular and important for research This is especially relevant for DENV and WNV rDIII proteins because their good immunogenic properties make them suitable as protein subunit vaccine candidates...
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