plasmodesmata and cell to cell communication in plants
Targeting New Pathways and Cell Death in Breast Cancer Edited by Rebecca L. Aft docx
Ngày tải lên :
23/03/2014, 17:20
... death domain-containing proteins, forming a complex comprising TRADD, TNF Receptor Associated Factor-2 (TRAF2), cellular inhibitor of apoptosis-1 (CIAP1), and the receptor-interacting protein-1 (RIP1) ... efficient in apoptosis induction DNA-damaging agents like doxorubicin, etoposide, cisplatin or bleomycin may induce apoptosis via both extrinsic and intrinsic apoptotic pathways (Fulda & Debatin, 2006) ... domain originating from a protein toxin, Pseudomonas Exotoxin A (PEA), was embedded in the fusion protein to mediate a translocation of the apoptotic proteins from an intracellular vesicle to...
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Báo cáo khoa học: Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells potx
Ngày tải lên :
30/03/2014, 13:20
... recruits other proteins, including paxillin, p130Cas, vinculin and talin in focal adhesions These protein complexes anchor the actin cytoskeleton and provide structural integrity to cells [16] The ... LPAinduced stimulation of PAK in A2058 cells, cells were pretreated with either tyrosine kinase inhibitor, genistein, or MAP kinase inhibitor, PD98059 Inhibition of tyrosine kinase by genistein ... stimulate cell spreading and motility in neuroblastoma cells [34] It is possible that different small G proteins are involved in LPA-induced cell motility in different cell types LPA stimulates tyrosine...
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TARGETING NEW PATHWAYS AND CELL DEATH IN BREAST CANCER pot
Ngày tải lên :
27/06/2014, 11:20
... death domain-containing proteins, forming a complex comprising TRADD, TNF Receptor Associated Factor-2 (TRAF2), cellular inhibitor of apoptosis-1 (CIAP1), and the receptor-interacting protein-1 (RIP1) ... efficient in apoptosis induction DNA-damaging agents like doxorubicin, etoposide, cisplatin or bleomycin may induce apoptosis via both extrinsic and intrinsic apoptotic pathways (Fulda & Debatin, 2006) ... domain originating from a protein toxin, Pseudomonas Exotoxin A (PEA), was embedded in the fusion protein to mediate a translocation of the apoptotic proteins from an intracellular vesicle to...
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Báo cáo y học: " Hyperglycemia alters enzyme activity and cell number in spinal sensory ganglia" ppsx
Ngày tải lên :
10/08/2014, 09:22
... representing minimal staining intensity (no staining) and 10 representing extremely dense staining (black) Page of (page number not for citation purposes) Journal of Brachial Plexus and Peripheral ... mouse line (characterized by the insulin promoter-linked overexpression of calmodulin in pancreatic β-cells) used in this study displays a well-characterized chronic hyperglycemia and hypoinsulinemia ... involved in the design and coordination of this study and participated in the writing of this manuscript and contributed both intellectually and practically to the content All authors read and approved...
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Báo cáo y học: "JNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and MMP9 expressions and cell migration in human LoVo colon cancer cells" ppsx
Ngày tải lên :
10/08/2014, 10:20
... Prostaglandin E2; ERK: extracellular signal regulated kinase; p38 MAPK: p38 mitogen-activated protein kinase; JNK: c-Jun Nterminal kinase; NF-κB: nuclear factor κ B; PI3-K: phosphatidylinositol 3-kinase; ... PKB: protein kinase B; uPA: urokinase plasminogen activator; tPA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor-1; MMP: matrix metallopeptidase; TIMP: tissue inhibitor of ... frequently present in advanced tumor stages, and in invasive tumor regions wherein cancer cells are in close proximity of inflammatory cells, suggesting that locally proteolytic and collagenlytic...
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báo cáo khoa học: "Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma" pptx
Ngày tải lên :
10/08/2014, 22:20
... L-arginine to synthesize NOHA from arginase, then increasing its inhibitory effect In contrast, it is also possible the growth of renal cell carcinoma cells is arginase II independent resulting in ... [36,37], indicating that these cells are more adept at circumventing L-arginine deficiency by increasing the recycling efficiency from L-ornithine to citrulline to convert L-arginine fast enough to ... cell carcinoma cells can modulate L-arginine levels to regulate both cell growth and T cell function Blocking arginase may lead to a decrease in RCC cell growth and aid in restoring immune function...
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The impact of and responses to HIV/AIDS in the private security and legal services industry in South Africa potx
Ngày tải lên :
22/03/2014, 18:20
... written into the policy, and dedicated staff and funding Introduction 1.1 Background Free download from www.hsrcpress.ac.za In October 2005, the Safety and Security Sector Education and Training ... employees in 34 workplaces involved mainly in mining and manufacturing in Botswana, South Africa and Zambia during 2000–2001, found a national prevalence rate of 14.5% in South Africa and showed ... should contain details about HIV, or whether this should be incorporated into training materials instead Policies that include information need to be updated regularly to ensure that the information...
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![Báo cáo toán học: " [18F]CFT synthesis and binding to monoamine transporters in rat" pdf](https://media.store123doc.com/images/document/2014_06/20/medium_gvf1403270414.jpg)
Báo cáo toán học: " [18F]CFT synthesis and binding to monoamine transporters in rat" pdf
Ngày tải lên :
20/06/2014, 20:20
... data, and in drafting the manuscript TG has contributed in acquiring the preclinical data, in analyzing and interpreting this set of data, and in drafting the manuscript MH has contributed in the ... contributed in the concept and design of the study, in acquiring data, in analyzing and interpreting data, and in drafting the manuscript and has critically contributed to and revised the manuscript, ... the final content of the manuscript OS has contributed in the concept and design of the study, in analyzing and interpreting data, and in drafting the manuscript, as well as in approving the final...
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A Professional''''s Guide To Data Communication In a TCP/IP World pptx
Ngày tải lên :
27/06/2014, 00:20
... on communications Conscious of my inability to treat each topic in detail, I have not tried to write a design manual My intention is to paint the scene, to chronicle what is involved, and to ... Lovenvirth for editing the final manuscript, and Jill Stoodley and Rebecca Allendorf for managing its production Finally, I want to thank my wife Joan, my son Kevin, and my grandsons Benjamin and Matthew ... layer is the Internet layer It contains IP and other associated protocols They provide the frame with originating and terminating addresses to guide the PDU to its destination The bottom layer is...
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Báo cáo y học: "The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets" pptx
Ngày tải lên :
09/08/2014, 14:22
... the tumour necrosis factor receptor-associated factor region (TRAF/C5) [7,10,11] and CD40, CCL21 and IL2RB [12,13] The integrin ανβ3 (ITGAV) locus contains 30 exons spanning more than 90 kb of ... genotyping be done in a large independent cohort to confirm whether ITGAV plays a role in RA The authors declare that they have no competing interests Authors' contributions JEH-M and TRM helped to ... and prepare the manuscript KAR, AJP-G and MEM provided technical support PG, AAH, PBBJ, LKS and PH helped to provide clinical recruitment and analyse data ND, JH and BPW helped to provide clinical...
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Báo cáo sinh học: "Nomenclature for naming loci, alleles, linkage groups and chromosomes to be used in poultry genome publications and databases" ppsx
Ngày tải lên :
09/08/2014, 18:22
... manuscripts and italicized in print Italics need not be used in catalogs It may be convenient in manuscripts, computer printouts and in printed text to designate a gene symbol by following it with ... This outline is aimed at suggesting nomenclature for use in journal publications and in the international chicken genome database (CHICKBASE) being developed at the Roslin Institute (Edinburgh), ... space and listed in alphabetical order when the gene order is not known: Loci are in on the joined by same a For text, the loci can be printed on a single line, phase and a slash indicating different...
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Báo cáo y học: " Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa" doc
Ngày tải lên :
10/08/2014, 05:22
... increase the uptake of HIV counselling and testing services thereby ensuring earlier diagnosis of HIV infection and initiation of ART The WHO clinical stage or was also an independent predictor ... staging of HIV disease This will be of importance in the realm of intensified efforts at scaling up access to ART when CD4 T cell counting monitoring is limited in peripheral health centres and ... Nabiryo C, Coutinho A: Use of WHO clinical stage for assessing patient eligibility to antiretroviral therapy in a routine health service setting in Jinja, Uganda AIDS Research and Therapy 2008,...
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Báo cáo y học: "Users'''' perspectives of barriers and facilitators to implementing EHR in Canada: A study protocol" pot
Ngày tải lên :
11/08/2014, 05:21
... gaps remain in understanding the challenges related to developing, implementing, and maintaining health information systems Understanding these challenges is critical to support future investments, ... encouraging clinicians to adopt EHR solutions, ensuring public confidence in the system, and using the information to inform policy and planning [58] This knowledge synthesis will lead to a proposed ... reviewing and synthesizing relevant literature on barriers and facilitators to implementing the EHR that are perceived by its various endusers and beneficiaries; and validating these findings...
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báo cáo khoa học: " Users'''' perspectives of barriers and facilitators to implementing EHR in Canada: A study protocol" potx
Ngày tải lên :
11/08/2014, 16:20
... gaps remain in understanding the challenges related to developing, implementing, and maintaining health information systems Understanding these challenges is critical to support future investments, ... encouraging clinicians to adopt EHR solutions, ensuring public confidence in the system, and using the information to inform policy and planning [58] This knowledge synthesis will lead to a proposed ... reviewing and synthesizing relevant literature on barriers and facilitators to implementing the EHR that are perceived by its various endusers and beneficiaries; and validating these findings...
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Báo cáo y học: "Persistence and compliance to antidepressant treatment in patients with depression: A chart review" doc
Ngày tải lên :
11/08/2014, 17:20
... highly motivated and encouraged to receive treatment Indeed, participants in clinical trials have been suggested to represent a minority of patients in routine clinical practice in terms of psychopathology ... reflect a bias in training and both direct and indirect influence of current and local standard of care [32] Since different treatment sites may have an impact on patients' behaviours towards antidepressant ... chart review and examined persistence and compliance to antidepressant drugs in outpatients with a major depressive disorder in psychiatric clinics in Tokyo, Japan We also tried to assess the...
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Báo cáo y học: " Responses of FEV6, FVC, and FET to inhaled bronchodilator in the adult general population" ppt
Ngày tải lên :
12/08/2014, 14:20
... graphs depicting: a) individual changes in forced vital capacity (FVC) in relation to average FVC, and b) individual changes in forced expiratory time (FET) in relation to average FET, in a bronchodilation ... change in FVC 92.0 ml and 2.5%, and change in FET 3.7 seconds and 50.0% Discussion The present study indicates that increase of FVC in response to inhaled salbutamol in the bronchodilation test in ... Yorba Linda, CA, USA) The beginning point of measurement is the back extrapolated time zero [14,25] and the end-point at the beginning of the end-expiratory plateau In cases where the total exhalation...
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Báo cáo y học: "Violence against civilians and access to health care in North Kivu, Democratic Republic of Congo: three cross-sectional survey" docx
Ngày tải lên :
13/08/2014, 14:20
... asked to help establish whether the house was abandoned or inhabited, and if inhabited, to find absentees Survey team members returned at least once to each house to try to find absentees In the ... and May 2009 in these three populations, with most occurring in Masisi and Kitchanga In Kabizo, 92 episodes of violence against individuals were reported, including two women who reported being ... having to flee and hide from enemies, houses being destroyed, family members, neighbours, and friends being killed or disappearing, witnessing someone being killed or raped, being raped, and...
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A Professional’s Guide to Data Communication in a TCP/IP World phần 3 pptx
Ngày tải lên :
14/08/2014, 13:20
... and assigned to manufacturers to imprint during the manufacturing process • The routing information indicator bit (bit in byte of the source address) indicates whether Token Ring source routing ... management protocols, for instance) in the same terminal or connections to different terminals (and Internet layer protocols) A given SAP is connected by a single DLCI to the sending/receiving machine ... that initiate communication, configure stations, test capabilities, and so forth • Bit is the P/F bit 4.1 Point -to- Point Links 4.1.2 63 PPP and SLIP Point -to- Point Protocol (PPP) and Serial Line...
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A Professional’s Guide to Data Communication in a TCP/IP World phần 4 ppsx
Ngày tải lên :
14/08/2014, 13:20
... Routing over Point -to- Point Links A point -to- point link has only two nodes Leased-line and circuit-switched WAN links, such as analog telephone lines, T-carrier, and ISDN, are examples of pointto-point ... IMD Interface matching device Figure 5.1 Connecting Client A to Server B mentation in forwarding and addressing, in data formats, and in transmission facilities Thus, changes in routes, forwarding ... table Since the table cannot be used for searching while being updated and reordered, two copies are maintained that can be interchanged as convenient—one for updating and reordering, and the...
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