planning a budget for a randomised controlled trial

... had overall responsibility for the trial, applied for a grant and commented on the draft paper All authors read and approved the final paper Acknowledgements Gelre Hospital, Apeldoorn, W A Spaans ... occurrence of a spontaneous viable IUP A viable IUP is defined as a pregnancy visible at ultrasound at a gestational age of ≥ 12 weeks with fetal cardiac activity, or the delivery of a child If an IUP ... participation are registered Randomisation Randomisation is performed during surgery by accessing a central internet-based randomisation program Randomisation is stratified for hospital, patient's age and...

Ngày tải lên: 13/02/2014, 06:20

... Ottawa, Canada 7Department of Medicine, University of Ottawa, Ottawa, Canada 8Institute of Population Health, University of Ottawa, Page of Ottawa, Canada 9Health Information Research Unit, McMaster ... Acknowledgements The authors thank Adalsteinn Brown, Alison Paprica, and Sarah Caldwell, MOHLTC, for supporting the study and identifying ways to allow for its operationalisation The authors also thank the ... for which we calculate the mean number of site visits/participant (e.g., calculating the mean over two months) if there are insufficient data for analysis Moreover, as part of a secondary analysis,...

Ngày tải lên: 10/08/2014, 10:23

... calcaneocuboid, cuneonavicular, and tarsometatarsal joints will be scanned in both longitudinal and transverse planes, along with the calcaneal and retrocalcaneal bursa, the plantar fascial calcaneal ... dorsal and medial 1st MTP joint; dorsal and plantar 2nd-4th MTP joints and the dorsal, lateral and plantar aspect of the 5th MTP joint [37] Proximally, the tibio-talar, subtalar, talonavicular, ... outcomes, as well as employing imaging techniques and thorough gait analysis should allow accurate monitoring, evaluation and appropriate alteration of treatments to achieve maximum treatment efficacy...

Ngày tải lên: 10/08/2014, 21:23

... such as calcaneal apophysitis creates uncertainty for clinicians attempting to pursue an evidence-based treatment approach These trials, and other similar trials, are needed to help clinicians ... footwear for use in this study has been donated by Adidas Australia Author details Cardinia Casey Community Health Service, Southern Health, Cranbourne, Australia 2Peninsula Community Health Service ... Frankston, Peninsula Health, Frankston, Australia 3Allied Health Clinical Research Unit, Southern Health, Cheltenham, Australia 4Physiotherapy Department, Monash University, Frankston, Australia...

Ngày tải lên: 10/08/2014, 21:24

... this trial as regional anaesthesia will be performed prior to plantar fascia injections Plantar fascia thickening Fusiform thickening of the plantar fascia is a well established feature of plantar ... Biological Impacts of Fluorination: Pharmaceuticals Based on Natural Products In Fluorine and Health: Molecular Imaging, Biomedical Materials and Pharmaceuticals Edited by: Tressaud A, Haufe G Amsterdam: ... this article as: McMillan et al., Ultrasound guided injection of dexamethasone versus placebo for treatment of plantar fasciitis: protocol for a randomised controlled trial Journal of Foot and Ankle...

Ngày tải lên: 10/08/2014, 21:24

... a visual analogue scale Statistical Analysis Statistical analysis will be performed using the SPSS (SPSS Corp, Chicago III, USA) software If the participant has bilateral symptoms, data from ... to treat plantar fasciitis Arch Intern Med 2006, 166:1305-1310 38 Price DD, McGrath PA, Rafii A, Buckingham B: The validation of visual analogue scales as ratio scale measures for chronic and experimental ... needling for plantar heel pain: study protocol for a randomised controlled trial Journal of Foot and Ankle Research 2011 4:5 Submit your next manuscript to BioMed Central and take full advantage of:...

Ngày tải lên: 10/08/2014, 21:24

... project, analysed the quantitative data and jointly assisted in the interpretation of the quantitative and qualitative data and revised the article All authors read and approved the final version ... the control arm The course and manual were acceptable and appreciated by participants and facilitators delivered it faithfully and as intended Group attendance was adequate except for the booster ... readability of the manual, Dr Alan Montgomery for help on the statistical aspects of this study, Dr Ali Heawood and Dr Lesley Wye for their qualitative advice, Alana Donaldson and Pei Tse our administrators...

Ngày tải lên: 11/08/2014, 15:22

... developing the statistical analysis plan SC was the trial coordinator and organiser of the recruitment strategy Aaron Beck, MD, acted as trial adviser All authors read and approved the final manuscript ... Methods/Design Trial summary The study proposed is a pragmatic randomized controlled trial with two parallel arms and approximately equal randomization of eligible patients to an active treatment group ... sample size is therefore estimated to be 152 patients There remains no agreed approach to calculate the sample size required for an economic evaluation, particularly in areas such as health anxiety...

Ngày tải lên: 11/08/2014, 15:22

... They can be used as stand-alone interventions or as an adjunct to other forms of intervention This is a rapidly growing area and a recent meta-analysis of studies evaluating such approaches for ... addressed before a large scale clinical and cost effectiveness evaluation of this approach Specifically, the trial will provide extensive quantitative and qualitative data on the acceptability of ... complete all the measures A second research assistant (RA2) then contacts the Clinical Trials Unit and provides information about which Trust the relative is in They are given the trial allocation...

Ngày tải lên: 11/08/2014, 15:22

... allocation on the primary and secondary outcome measures after adjusting for baseline values An intention-to-treat approach will be used for primary analyses A secondary per-protocol analysis ... a constant balance between assisting patients to engage in an exercise program, whilst making it achievable and affordable and able to be self-managed Exercise bands have been selected as they ... sessions for participants with low motivation Encourage moderate level activities if physical limitations are present the hospital database and patient files Voluntary programs including yoga, art...

Ngày tải lên: 11/08/2014, 15:22

... will also be asked to score satisfaction with care on a Visual Analogue Scale (VAS) Statistical analysis Primary outcomes are psychosocial functioning; course, prevalence and severity of psychiatric ... made, formulated as a contract, in which goals and treatment activities are recorded • Working with the treatment plan based on systematic care needs assessment, and that will focus specifically ... provided actively outreaching care when a patient was at risk of losing contact with mental health workers Each patient made a ‘relapse prevention plan’, aimed at the early recognition of relapses...

Ngày tải lên: 11/08/2014, 15:22

... Biology and Environment, Australian National Page of University, Australia 2ORYGEN Research Centre, University of Melbourne, Australia 3Centre for National Research on Disability and Rehabilitation ... psychometric measures, screening and diagnosis tests, modelling longitudinal data, and the conduct and analysis of controlled trials and interventions in mental health KK Trial Manager for the WebGAD prevention ... prevention trial and Research Assistant to Professor Christensen PJB Expertise in statistical analysis and data management of large-scale behavioural research studies, and experience in the design and...

Ngày tải lên: 11/08/2014, 16:22

... Random allocation of diary periods means that data can be imputed for the whole trial period and used as a patient record of their depression free days, as well to validate the scores calculated ... II; DSM IV: Diagnostic and Statistical Manual of Mental Disorders, 4th edition; WASAS: Work and Social Activity Scale; SAPAS: Standardised Assessment of Personality - Abbreviated Scale; CSRI: Client ... Mental Health Research Network Clinical Studies Officer All participants will be asked at the outset of the final assessment not to reveal their trial arm allocation As a check on potential bias,...

Ngày tải lên: 11/08/2014, 16:22

... Cognitivebehavioral therapy for PTSD in children and adolescents: A preliminary randomized controlled trial Journal of the American Academy of Child and Adolescent Psychiatry 2007, 46:1051-1061 22 Cobham ... approach; is age appropriate, incorporates creative drawing and writing tasks and aims to: provide psychoeducation about the role of thoughts, behaviours (avoidance) & physical reactions in anxiety ... parental psychopathology, assessed by the Depression Anxiety and Stress Scale [DASS; [39]]; parental state and trait anxiety, measured by the State Trait Anxiety Inventory [STAI; [40]] Kenardy...

Ngày tải lên: 11/08/2014, 16:22

... Cite this article as: Kenardy et al.: Protocol for a randomised controlled trial of risk screening and early intervention comparing child- and family-focused cognitive-behavioural therapy for PTSD ... Cobham V, Nixon RDV, McDermott B, March S: Protocol for a randomised controlled trial of risk screening and early intervention comparing child- and family-focused cognitive-behavioural therapy for ... Brisbane QLD 4101, Australia 4School of Psychology, Flinders University, Adelaide SA 5001, Australia Received: 19 January 2011 Accepted: 20 January 2011 Published: 20 January 2011 References Kenardy...

Ngày tải lên: 11/08/2014, 16:23

... had intended the FolATED trial to be paperless, we have replaced the electronic trial database by a rigorous paper-based data collection system We have therefore amended the section on data handling ... electronically Electronic data will be stored on a central computer at each centre Field investigators will use laptops that will be cleared of data after every visit once uploaded to the central database ... Moat S, Pirmohamed M, Slegg G, Tranter R, Wilkinson C, Russell I: Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial BMC Psychiatry...

Ngày tải lên: 11/08/2014, 17:20

... Foot All joints distal to the talocrural joint Ankle The talocalcaneal, talonavicular, talo-crural and distal tibial-fibular joints Knee The patellar-femoral articulation, tibial-femoral articulation ... sternal-costal joint, costalchondral joints and sternal-clavicular joint Elbow The ulnar-humeral articulation and the proximal radioulnar joint Wrist The radiocarpal joint, distal radio-ulnar joint and ... Maltby S, Hulse M, Thomas A, Hodson A, Football Association Medical Research Programme: The Football Association Medical Research Programme: an audit of injuries in professional football–analysis...

Ngày tải lên: 13/08/2014, 14:20

... Retraction: A descriptive study of a manual therapy intervention within a randomised controlled trial for hamstring and lower limb injury prevention Wayne Hoskins* and Henry Pollard Department ... ethics committee approval it has been retracted References Hoskins W, Pollard H A descriptive study of a manual therapy intervention within a randomised controlled trial for hamstring and lower limb ... Chiropractic, Faculty of Science, Macquarie University, NSW 2109, Australia * Corresponding author: Wayne Hoskins waynehoskins@iinet.net.au Email: Wayne Hoskins waynehoskins@iinet.net.au Henry Pollard...

Ngày tải lên: 13/08/2014, 15:21

... time, two factorial analyses of variance (ANOVAs) with repeated measures design were calculated A series of additional analyses of covariance (ANCOVAs) were conducted entering age, sex and severity ... school-age children after RTAs by means of a randomised controlled trial Our basic idea was that an early intervention might have the potential to prevent future psychological symptoms Specifically, ... approach for dealing with traumatic symptoms in an early stage after an RTA Young children can profit from a single-session early intervention around 10 days after an RTA We suggest involving at least...

Ngày tải lên: 13/08/2014, 18:21

... TA, Mensah GA, Alexander RW, Anderson JL, Cannon RO, Criqui M: Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare ... Chicago, IL, USA) was used for all statistical analyses A P value < 0.05 was considered to be statistically significant The results are reported as mean ± SD values Table 1: Baseline characteristics ... 38(2):149-157 Lakka TA, Venalainen JM, Rauramaa R, Salonen R, Tuomilehto J, Salonen JT: Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction...

Ngày tải lên: 20/06/2014, 00:20