placentation angiogenic factors and the pathogenesis of preeclampsia

... secretion of Simultaneous application of TNF-α and IFN-γ to endothelial cells causes an increase in NPY, upregulation of the Y5 receptor, and complete loss of the Y2 receptor, together with an ... maintained and exacerbated by the activity of DPPIV Nevertheless, in two mouse models of inflammatory arthritis, the severity of joint damage correlated directly with levels of SDF-1α where the efficacy ... measured This is complicated further by a lack of understanding of the breadth of substrate and inhibitor specificities for the DASH family This is illustrated well by the CD26-knockout mouse that...

Ngày tải lên: 09/08/2014, 07:20

... control of HIF synthesis, HIF controlling PHD synthesis, putative competing/intervening impacts of HIF-3α and PHD-3, cross-talk of HIF and other key regulators of gene expression (STAT, p-300 and others), ... or in the inner stripe and inner medulla following the induction of distal tubular hypoxic injury by radiocontrast agent, or after the inhibition of prostaglandin or NO synthesis or with their ... progression via upregulation of growth promoting and angiogenic factors [35] Potential usage of HIF modulation in clinical practice The impact of HIF stimulation on the expression of HIFdependent tissue-protective...

Ngày tải lên: 14/08/2014, 07:21

... Anatomy of cerebral veins and sinous The veins of the brain have no muscular tissue in their thin walls and possess no valves as compared to other types of veins They emerge from the brain and lie ... features and brain images of CVT Our study found some genetic and acquired risk factors of CVT Our study successfully determined the role of D-dimer test in the diagnosis of CVT The thesis includes ... risk factors of CVT To determine the sensitivity, specificity, positive predictive value and negative predictive value of D-dimer test in the diagnosis of CVT 2 NEW CONTRIBUTION OF THE THESIS...

Ngày tải lên: 21/10/2014, 21:52

... et al, in their study, have evaluated the link between the timing of conception with risk of preeclampsia [13] They found the highest risk of preeclampsia in conceptions occurring in the summer ... different frequency of preeclampsia in the dry and wet seasons that occur in Zimbabwe [12] All these studies have assessed if there was a seasonal variation in the incidence of preeclampsia Interestingly ... daily rainfall and morning barometric pressure) were acquired from the Regional Meteorological Centre, Mumbai for the study period The incidence of preeclampsia and eclampsia and the meteorological...

Ngày tải lên: 13/02/2014, 06:20

... increase in apoptosis [73] The authors of this study ascribe the regulation of outgrowth of limb buds and patterning of the digits to the chicken AP-2 The role of AP-2a was further studied in zebrafish ... tumorigenesis and genetic diseases [47] Most analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target gene ... because of the severe skeletal defects in growth and the development of face and limbs [17–19] Donner et al tried to link the expression of AP-2a in these tissues to upstream signaling pathways They...

Ngày tải lên: 16/02/2014, 09:20

... costs and the expenses of the social and health services are increasing The report analyses the factors influencing the use of social and health services by the elderly On the basis of the analysis, ... means of ordered logit models the impacts of age, dependency and other factors on probabilities to use home and community care for the elderly With these models and the age profile of the institutional ... numerous In the independent ordered logistic regression of the DEPENDENCY on reported sickness and injuries of the respondents in the Table 1, the role of mental and physical factors is evident The figures...

Ngày tải lên: 14/03/2014, 17:20

Ngày tải lên: 16/03/2014, 03:20

... proliferation and blocking apoptosis in the pathogenesis of RA Results GM-CSF induces the proliferation of MH7A cells and the expression of MLN51 Our recent study has shown that GM-CSF is involved in the ... is upregulated in the FLSs of RA patients, and is enhanced days after GM-CSF treatment [7] In the present experiments, we assessed the dose and time kinetics of the effects of GM-CSF on MLN51 ... left untreated The cells were harvested and assessed by western blot analysis for the expression of MLN5 1and FLIP proliferation of RA FLSs through the upregulation of MLN51 [7] In the present study,...

Ngày tải lên: 23/03/2014, 07:20

... between TST positivity of contacts and gender, age, closeness to the index case, BCG scar presence and radiological degree of the disease of index case The rate of TST positivity of household contacts ... the second of classmates and teachers and the third of more distant contacts They found that 88% were infected in the first group 42% in the second group and 18% were infected in the third group ... female contacts considered their health important, the majority of them have a lot of time because of not working In this study the frequency of TB in household contacts of pulmonary TB cases was...

Ngày tải lên: 29/03/2014, 03:20

... tested, K is the number of risk factors in the asset pricing model, µ is a column vector of mean returns of the risk factors, Ω is the unbiased estimate of the covariance matrix of the risk factors ... is the difference between the monthly return of government bonds and the one-month risk-free rate of the previous month The proxy of the default risk is the difference between the return of corporate ... maturity of 1-3 years and a market value weighted short position of the remaining maturities The construction of this portfolio is based on the sum of the intercept and residuals of equation 3, for the...

Ngày tải lên: 29/03/2014, 06:21

... volume of lychee, selling prices, distance to markets, gender of producers and participation in the lychee association Then, the 125 Factors affecting lychee productivity and the choices of fresh ... probability of an individual making a choice is a linear function of the individual attributes (Pindyck and Rubinfeld, 1981) The logit technique allows examination of the effect of a number of variables ... CONCLUSION AND POLICY IMPLICATIONS There were several factors affecting the lychee productivity and the choices of fresh lychee marketing of producers in Thanhha district, Haiduong province In the overall...

Ngày tải lên: 06/08/2014, 18:22

... Although the contribution of livestock to the GDP of the Luong Son district is not high, it is the main food supply for people here In Luong Son, AI appeared in the years of 2003 and 2004 at 2/3 of the ... 29.90% of farmers cured sick animals themselves, and did not have a clear understanding about diseases and mechanisms of drug actions The above behaviors of local people raised the risk of drug ... symptoms 3.6 Behaviors of local people to the outbreak of diseases 115 Investigation of some social factors on the evolution of Avian Influenza (AI) follow up the command to destroy your infected...

Ngày tải lên: 06/08/2014, 19:20

... recorded in stand No The June and July precipitation of the actual year is most significant for 100% of trees and for almost 80% of trees in this stand, and only for 10% or 5% of trees the precipitation ... species The method of multiple correlations was used for the derivation of the models of dependence of increment indexes on selected climatic factors together for all trees in each stand and together ... precipitation in August of the previous year and July of the actual year is significant for all stands In other cases precipitation in July of the previous year and June of the actual year as well...

Ngày tải lên: 07/08/2014, 10:21

... depression, and odor of acetone on the breath Endometritis was diagnosed weeks postpartum by examination by the authors and diagnosed by the presence of the following clinical signs: cloudy discharge and ... compared using the chi-square test Evaluation of the effect of retained placenta on the occurrence of reproductive and metabolic disorders Cows were grouped based on the occurrence of retained placenta ... during the warm season for the first lactation and during the cold season for the second lactation Cow parity and calving season were eliminated from the final model since they did not influence the...

Ngày tải lên: 07/08/2014, 18:21

... enhances activation of eosinophils in EoE specifically Page of The increased global expression of bFGF led to the investigation of the local expression bFGF of the esophageal biopsies of the subjects ... subsets and can be found in a variety of tissues, including epithelial and mesenchymal tissue [20] bFGF increases the half-life of cells and could possibly increase the overall lifetime of the eosinophil ... essential to the transcription of ERK [18] and ERK feeds into the eotaxin-3 pathway, potentially further activating the eosinophil and improving its sensitivity and migration towards eotaxin in the esophageal...

Ngày tải lên: 08/08/2014, 21:20

... integration: I Symmetry and convergence of the corticocortical connections of the left and the right principal sulcus (PS) and the left and the right supplementary motor area (SMA) in the rhesus monkey ... [10,11] While there is a variation in the age of onset of epilepsy, there is a trend toward later onset epilepsy and a duration of to 10 years between the onset of chronic epilepsy and PIP [9,11] ... knowledge of the etiology of psychosis, a component of a Todd's phenomenon may not be entirely excluded By considering the generally common clinical features of PIP, and calling on studies of the pathophysiology...

Ngày tải lên: 08/08/2014, 21:20

... Comparison of daily versus thermodynamic constants diurnal and N is the number of diurnal observations The number of points, n, for each daytime period in which I was recorded to assess i the effect of ... outside of the general cluster of points The specific conditions of those days were investigated in detail and were found to result from rain night The effects of nighttime recharge in general and ... here and in the previous study may involve the length and timing of the present study (266 d through an entire growing season) versus that in the previous study (50 d in the early part of a growing...

Ngày tải lên: 09/08/2014, 04:20

... high levels of C5a in SF [21] and correlation of the levels of C5a with the number of neutrophils present in the SF of patients with RA [22] More direct evidence for the role of the complement ... although the relative contributions and the hierarchy of these two pathways in the manifestation of disease are still unclear In FcγR−/− mice, in which the surface expression of FcγRI and FcγRIII ... most striking characteristics of the K/B × N model is the extremely high titer of specific autoantibodies throughout the life of the diseased mice Titers in the order of 10 mg/ml specific anti-GPI...

Ngày tải lên: 09/08/2014, 06:23

... Yudoh and colleagues [1] further analyzed the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional inactivation of ... chondrocytes [11] Conclusion The results provided in the study by Yudoh and colleagues and previous reports by us and other groups strongly support the notion that HIF-1 is of pivotal importance in ... expression of hypoxia-inducible factor (HIF)-1a in articular chondrocytes: involvement of HIF1a in the pathogenesis of osteoarthritis Arthritis Res Ther 2005, 7:R904-R914 Silver IA: Measurement of pH and...

Ngày tải lên: 09/08/2014, 07:20

... stages of OA Materials and methods Sources of tissues Aborted human embryos were obtained according to the regulations of the Ethics Committee of the Medical Faculty of the University of Göttingen, ... to the OA grades (I – IV) proposed by Collins and McElligott [31] in the case of the 12 patients and classified as age-dependent healthy in the case of the control cartilage samples None of the ... B.Sc., for editing the manuscript and the Medical Faculty of the University of Göttingen for grants to NM Parts of the work were taken from the doctoral theses of TSC and MK References Hedbom E, Antonsson...

Ngày tải lên: 09/08/2014, 07:20