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Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"
... have not yet been addressed. The first question is whether the expression level for RIZ1 varies over the progression of cancer; and the second question is whether the PR domain alone possesses ... types of PRDMs have been identified in humans [15, 18]. Most of them are located near the N-terminal portion of the proteins followed by zinc-fingers, and are involved in the reg-ulation of ... activity. The PR domain of RIZ1 possessed anticancer activity from the transfec-tion studies. This finding leaves us an important question on the roles the other structural components of RIZ1...
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Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"
... translocation of the internally sequence of PreS1 domain onto the viral surface [62, 63]. This supports the hypothesis that the low pH in the endosome may induce the conformation change of HBV surface ... a result of the variation of loading, because the expression of the thimet oligopeptidase gene in the same condition did not show any difference (Figure 2C). The over-expression of the SPIK ... target, further confirmed the role of LHBs in the HBV attachment [23]. Recently, the attachment site of LHBs was functionally narrowed down to the amino acids 21–47 of preS1 by employing synthetic...
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Computer illiteracy as one of the main problem of business student
... we depend on other people.Causes The first cause of the problem of computer illiteracy is the lack of useful information in the course of information science. The second cause is unwillingness ... them, instead of learning how to do it themselves. The third cause is lack of access to computer. The fourthcause is dissatisfactory school base. The fifth cause is insufficient allocation of ... - is the main problem of student who spend a lot of time and force for solvinga problem, which can be solved with the help of PC faster.And all we know that computer literacy is on of the main...
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Infelicities of the Intended Meaning of Canonical Texts and Norms Constraining Interpretation
... that24 Of course, if there were no fact of the matter regarding the level of generality of the authorities’intentions, there might well not be a fact of the matter regarding the words or even the language ... inconsistent with each other, there is no fact of the matterabout what the rule makers intended. What they intended is rather the product of whatever norm selects the appropriate level of generality atwhich ... wouldprescribe the level of generality for interpreters to follow.24In our view,however, there is a fact of the matter. For example, there is a fact of the matter by virtue of which it is true that the...
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An overview of the clinical management of spasticity
... emphasizing that the situa-tion is usually more complex. In the above example,relief of the spasticity in the biceps may not lead toimprovement in the function of the arm, as otherfeatures of the UMN ... bedclothes. A detailed appraisal of the pattern of spasticity may enable the individ-ual to relieve many of the functional problems. Both the clinician and the individual should be aware of potential ... spasticity. The followingchapters in the book outline the detail of the dif-ferent approaches to the management, but this sec-tion attempts to provide an overview of the process(Fig. 1.1).Aims of...
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Tài liệu 1992 CONSTITUTION OF THE SOCIALIST REPUBLIC OF VIETNAM (As Amended 25 December 2001) ppt
... forces on the basic of the combination of construction with defence, of the strength of the people's armed forces with that of the entire people and of the strength of the tradition of national ... of the Standing Committee of the National Assembly, decrees and decisions of the President of the State and texts of the Government and the Prime Minister, Ministers and other members of the ... Assembly is the permanent body of the National Assembly. The Standing Committee of the National Assembly consists of: - The Chairman of the National Assembly; - The Deputy-Chairmen of the National...
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Tài liệu PREVENTING DISEASE THROUGH HEALTHY ENVIRONMENTS: Towards an estimate of the environmental burden of disease doc
... the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, ... in the South-East Asia Region; 50% (38—63%) in the European Region; and 64%(51—77%) in the Region of the Americas. The potential of environmentalmanagement to reduce the disease burden of malaria ... exposures will both improve the health and the lives of urban slum dwellers – one of the key targets of MDG-7. The underlying message of this study is that both the health sector and non-health...
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Tài liệu INDUSTRIAL TECHNOLOGY ASSESSMENTS: An Evaluation of the Research Program of the Office of Industrial Technologies doc
... secure the services of eminent members of appropriate professions in the examination of policy matterspertaining to the health of the public. The Institute acts under the responsibility given to the ... and priorities of each IOF group and consider several factors, such as the size of the industrial community, the potential effect of the research on OIT goals, the ability of the industry to ... collabo-rations. These guidelines could then be used in the implementation of the IOFstrategy throughout the OIT program. The panel made the following recommen-dations concerning the implications for the...
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Tài liệu Characterization of the Polymorphic Behavior of an Organic Compound Using a Dynamic Thermal and X-ray Powder Diffraction Technique pptx
... understand the relationships among the polymorphs. Heats of solution of the various polymorphs need to be measured, inorder to prove the relative order of stabilities for these solidforms. At the ... a wavelength of 1.540600 Å. The X-ray data was collectedusing an MBraun curved PSD with a chamber depth of 1 cm. The focal radius of the system was 57 mm, and the 5 cm length of the PSD subtended ... sampleswhich were isolated. These results are summarized inTable 4. In many cases the mixture of polymorphs can beaccounted for by the addition of the DSC results of the component pure polymorphs....
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Tài liệu Guideline on Network Security Testing: Recommendations of the National Institute of Standards and Technology ppt
... None of these tests by themselves will provide a complete picture of the network or its security posture. Table 3.1 at the end of this section summarizes the strengths and weaknesses of each ... for the testing organization to alert other security officers, management, and users that network mapping is taking place. Since a number of these test mimic some of the signs of attack, the ... result in the testing team learning more about the targeted network and its potential vulnerabilities, or they may induce a change in the state of the security of the targeted network. In either...
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Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
... Laboratory4Friends of the North Fork of the Shenandoah RiverPrepared in cooperation with the Friends of the North Fork of the Shenandoah RiverOpen-File Report 2008–1093U.S. Department of the InteriorU.S. ... not known if the trace levels of para-cresol and 17α-ethynylestradiol are the sole causes of the estrogenic response in these samples because of the large numbers of natural and synthetic polar ... ensure the reliabil-ity of the data obtained. The QC samples for the SPMDs and POCIS consisted of fabrication and field blanks intended to determine the presence of any contamination of the sampler...
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Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx
... function of the CXXXCmotif of human Sco proteins could therefore be impli-cated not only in the maturation of the CuAsite of Cox2 but also in the maintenance of cellular copperhomeostasis. The ... Blackburn NJ(2011) The essential role of the Cu(II) state of Sco in the maturation of the Cu(A) center of cytochrome oxi-dase: evidence from H135Met and H135SeM variants of the Bacillus subtilis ... capable of < 20% reconstitution of Cox2 in vitro [89] and that the effect of the histidine-to-methionine mutation on the redox potential of the CXXXC motif has not beeninvestigated, all the available...
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