physiological and laboratory markers of drug effect

... patients, and the clinical manifestations usually subside after withdrawal of the offending drug Nevertheless, some patients go on to develop serious vasculitic manifestations if the offending drug ... antibody (ANCA); review of literature Clin Nephrol 1997, 47: 336-340 Rubin RL: Autoantibody specificity in drug- induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs Clin Biochem ... to the presence of ANCAs directed at more than one neutrophil cytoplasm antigen as a characteristic feature of DIV [4,5] Others have observed a characteristic development of ANAs and antihistone...

Ngày tải lên: 09/08/2014, 07:20

... 19 20 20 21 22 23 2.6 Effect of Extraction Methods on Antioxidant Activity of Herbs 2.6.1 Effect of Extraction Solvents 2.6.2 Effect of Extraction Time 2.6.3 Effect of Extraction Temperature 24 ... Understanding the Composition and Complexity of Rural Households Agriculture and Human Values 22:87-103 Druiynska, B, A & Wotosiak, R 2007 The Influence of Time and Type of Solvent ,on Efficiency of ... Barrera, M.R 1992 Effect of Food Preparation on Qualitative and Quantitative Distribution of Major Carotenoid Constituents of Tomatoes and Several Green Vegetables Journal ofAgricultural and Food Chemistry...

Ngày tải lên: 05/05/2014, 08:39

... temperature) and resuspended in Mops medium [5.5 gÆL)1 of Mops free acid, 5.1 gÆL)1 of Mops sodium salt, 0.5 gÆL)1 of NaCl, gÆL)1 of NH4Cl, 0.06 gÆL)1 of Na2HPO4Æ2H2O, 0.05 gÆL)1 of KH2PO4, mm ... representation of the relative densities of the free DNA measured at increasing concentrations of HbpR The percentage of free DNA was calculated from densitometric measurements of the radiolabeled bands ... objectives of this work were to identify critical motifs in the binding site for HbpR and to examine the necessity of the sensing A-domain of HbpR for DNA binding The role of individual nucleotides and...

Ngày tải lên: 07/03/2014, 17:20

... precondition for drug abuse, creating something of a vicious circle D Trade and balance of payments The effects of the illicit drug industry on both the balance of trade and the balance of payments of a ... Sweden, Switzerland and the United Kingdom of Great Britain and Northern Ireland Sources: UNDCP country profiles United States Department of Health and Human Services (Substance Abuse and Mental Health ... the illicit drug problem The order of magnitude of the extent of the illicit drug problem should be established in the light of at least two of the unique characteristics of illicit drugs: first,...

Ngày tải lên: 08/03/2014, 06:20

... Function and Investors’ Perceptions of Audit Effectiveness: Effects of Regulatory Change and recommend that it be accepted as fulfilling the dissertation requirement for the Degree of Doctor of Philosophy ... evidence of individual investors’ perceptions of the costs and benefits of the current standard Siding with those parties lobbying for relief from the requirements of SOX 404 and AS2, the PCAOB and ... standard and the proposed standard For expositional purposes, I refer here to the two standards presented in the experimental setting as AS2 (the existing standard) and AS5 (the proposed standard)...

Ngày tải lên: 01/06/2014, 14:04

... interleukin-6 (IL-6) and Intercellular Adhesion Molecule-1 (ICAM-1) as markers of inflammatory response, and matrix metalloproteinase (MMP-9) and cellular fibronectin (cFn) as markers of blood brain ... serum levels and established biomarkers of different mechanisms of brain injury which take place after acute ischemic stroke The implication of the selected biomarkers in different pathophysiological ... onset and lower levels of the inflammatory biomarkers ICAM-1 and IL-6 at 24 hours Previous studies by our group have reported associations between serum levels of these inflammatory markers and...

Ngày tải lên: 18/06/2014, 19:20

... interleukin-6 (IL-6) and Intercellular Adhesion Molecule-1 (ICAM-1) as markers of inflammatory response, and matrix metalloproteinase (MMP-9) and cellular fibronectin (cFn) as markers of blood brain ... serum levels and established biomarkers of different mechanisms of brain injury which take place after acute ischemic stroke The implication of the selected biomarkers in different pathophysiological ... onset and lower levels of the inflammatory biomarkers ICAM-1 and IL-6 at 24 hours Previous studies by our group have reported associations between serum levels of these inflammatory markers and...

Ngày tải lên: 20/06/2014, 03:20

... types of drug toxicities that occurred during the first year of HAART Efavirenz hypersensitivity reactions were the cause of drug toxicities within the first 16 weeks of HAART Between weeks 16 and ... up to 75% of drug switches for toxicity within the first three years of first-line HAART [21] In South Africa, there is an ongoing debate about whether or not the side -effect profile of HAART ... data The average age of the cohort was 34 years (standard deviation: 4) and 74% of patients were female (n = 219) Eighty-six percent of patients (n = 370) had WHO Stage and disease The median...

Ngày tải lên: 20/06/2014, 08:20

... visually to the nearest tens of percent Data from field and laboratory measurements were processed and statistically evaluated by the Excel and QC Expert software Analysis of variance (two factors ... mountain populations” This paper presents the results of the health and physiological state of young spruce stands established by outplanting of specifically sorted planting material (comprising ... traits of young spruces with known growth rate in a nursery and after outplanting are carried out in the framework of the grant project “Conservation of the stability and biodiversity of Norway...

Ngày tải lên: 07/08/2014, 10:21

... third and fourth week of drought Both growth stage of seedlings and drought period had significant effect on needle chlorophyll fluorescence (Fv/Fm ratio) (p < 0.001) Fv/Fm ratio of the needles of ... seedlings, one each in the 2- and 3week drought periods, and four growing seedlings, all of them in 4-week drought period died Consequently, no clear effect of either growth stage of seedlings at planting ... potentials (Ψshoot pd and Ψshoot d), and (b) chlorophyll fluorescence (Fv/Fm) of the previous year needles in dormant and growing seedlings before planting (0) and after 1-, 2-, 3- and 4-week postplanting...

Ngày tải lên: 08/08/2014, 00:21

... capacity of C sativa in older coppices, in accordance with the results of Deweirdt and Carlier [16] The study of variations of leaf morphology in response to stand age and in two different periods of ... LMA, and LTD in OC than in YC confirmed the early onset of senescence, according to the results of Buchanan et al [9], Gratani and Varone [24], and Ogaya and Peñuelas [43] The values of LT and ... Canary Islands: I The site, stand structure and stand leaf area distribution, Trees 11 (1996) 34–40 [40] Mousseau M., Effects of elevated CO2 on growth, photosynthesis and respiration of sweet...

Ngày tải lên: 08/08/2014, 00:22

... to appear, a sample of 50 seedlings/treatment was taken to determine the consumption of food reserves and build-up of shoot and root dry matter mm germination Knowledge of physiological processes ... high standards required for seed storage today and In the context of a long-term storage project at the University of Hannover, the physiological development during storage and germination of different ... for the development of seed-storage methods The current rule of thumb is that a water content of 40% and a temperature of -4 °C are the minima acorns require to survive (Holmes and Buszewicz, 1956;...

Ngày tải lên: 08/08/2014, 19:21

... male-female interactions (Gaude and Dumas, 1987) After silver nitrate staining, qualitative and quantitative differences could be observed, related to the presence of P nigra and P alba pollen tubes ... Molecular and cellular events of self-incompatibility Int Rev Cytol 107,333-366 (1982) Identification of concanavalin A-binding proteins after sodium dodecyl sulfate-gel electrophoresis and protein ... Knox R.B (1983) Callose and determination of pistil viability and incompatibili0 ty Theor AppL Genet 67, 1-10 Villar M., Gaget M & Dumas C (1988) Microisoelectric focusing of proteins from single...

Ngày tải lên: 09/08/2014, 04:20

... complex process of puberty, affecting the development of facial, body, and pubic hair, deepening of the voice, and muscle development Physiologically, androgens regulate spermatogenesis and help maintain ... ladder of 100 bp; = exon with a size of 528 bp; = exon with a size of 172 bp; = exon with a size of 378 bp; = exon with a size of 516 bp; = exon with a size of 289 bp Melo et al Journal of Medical ... incapacity or reduced capacity of the AR to transactivate androgen-responsive genes in target cells, and leads to abnormal differentiation and development of male internal and external genitalia, leading...

Ngày tải lên: 10/08/2014, 23:20

... observed in 12 (50%) of the 24 dSSc patients and in 10 (41.7%) of these patients FVC and DLCO ≤ 69% occurred Of the 76 lSSc patients, FVC and DLCO ≤ 79% was observed in (5.3%) and FVC and DLCO ≤ 69% ... DLCO and patients with normal PFTs Characteristics of the groups are detailed in Table 16 (16.0%) patients had FVC and DLCO ≤ 79%: 12 of these patients had FVC and DLCO ≤ 69% and had FVC and DLCO ... diagnostic approach and analysing the characteristics of patients with alveolitis with the aim of identifying those factors that will potentially act as markers of alveolitis An alveolar and interstitial...

Ngày tải lên: 12/08/2014, 18:22

Ngày tải lên: 13/11/2014, 09:42

Ngày tải lên: 13/11/2014, 09:48

... on the one hand, facilitators of professional development, and on the other hand, assessors of the quality of teachers’ work To establish effective supervisory relations, Gitlin and Smyth (as ... usefulness of simple teaching aids such as pictures and handouts: Simple teaching aids made by teachers such as pictures and hands outs are practical and useful They can enhance the effectiveness of ... throughout Doff (1988) suggests a set of criteria for evaluating lesson effectiveness in the forms of questions His criteria focus on the aim and procedures of the lesson, teacher’s instruction and class...

Ngày tải lên: 19/03/2015, 10:34

... Structure and components of the Permeability Transition Pore Complex 30 Results Figure Effect of drug C1 on cell survival of various cell types 54 Figure Morphological and long term effects of drug ... upregulation of the orphan nuclear receptor NR4A3, and also NR4A1 which is a member of the same family of receptors This study characterizes the role of nuclear receptors NR4A1 and NR4A3 in drug C1 ... silencing corresponds to abrogation of apoptosis, but only when the drug dosage is low At higher doses of the drug the silencing of NR4A3 and the subsequent lowering of VDAC1 levels in mitochondria...

Ngày tải lên: 14/09/2015, 14:04