... stimuli [11-13] However, in spite ofthe relevance of these reservoir cells in the control of viral persistence, the mechanisms responsible of apoptosis resistance of persistently-infected cells ... independent ofthe magnitude of viral replication Apoptosis resistance is independent ofthe magnitude of viral replication A) Jurkat and J1.1 cells were incubated in the presence or absence of 1000 ... experiments of apoptosis by Hoechst and APOBrDU DOC and GAR were responsible of experiments using Western blot analysis, and contributed to writing ofthe manuscript MB, RL and MS performed and interpreted...
... archives in the Netherlands, namely KITLV (The Royal Netherlands Institute of Southeast Asian and Caribbean Studies) in Leiden, The Wereldmuseum andThe Netherlands Photo Museum in Rotterdam andthe ... together different kinds of photographs (miscellaneous) that not fit into the themes of other albums The sizes ofthe photographs vary, and so the depicted subjects Based on the quality ofthe photographs, ... collections of different museums and archives in the Netherlands, namely, the Tropenmuseum ofthe Royal Tropical Institute (KIT) andThe Print Room ofthe Rijksmuseum in Amsterdam; the Royal Netherlands...
... particular, the four-stranded b sheet formed by the aminoacid residues at the N- and C-termini of PR contribute close to 75% ofthe total Gibbs energy [15] The importance of this four-stranded b ... dimer (residues 1–5 and 95–99) Additional interactions include a complex salt bridge between D29 and R87 of one subunit and R8 ofthe other subunit Thermodynamic analyses ofthe dimeric PR molecule ... interactions in the dimer include interactions between the catalytic triad residues (D25-G27), I50 and G51 at the tip ofthe flaps, andthe antiparallel b sheet formed by the four termini in the dimer...
... capacity and also modulating the catalytic properties ofthe enzyme [19] To extend the information about the role ofthe noncatalytic SBD regions and their effect on the C-terminal CD, we further ... showing a lack of interaction for the individual SBDs and also in the absence ofthe D(316–344) and D(495–535) regions ofthe D2 and D3 domains, respectively Kinetic parameters of co-purified recombinant ... that the N-terminal region of SSIII can interact with SSI [13] The possible regulatory role of this protein makes this isoform a potential target for the manipulation ofthe level and quality of...
... clinical trial of protective ventilation strategy Further evidence is required to determine whether the soluble Fas ligand actually originated in the lungs Irrespective ofthe source, these findings ... mg/kg) and did not result in overt ALI before initiation ofthe ventilation protocol; andthe mechanical ventilation protocol used levels of Vt that did not lead to disruption ofthe epithelial ... dissemination of bacteria and infection Schortgen and coworkers [53] evaluated the effect of Vt reduction and alveolar recruitment on systemic and contralateral dissemination of bacteria and inflammation...
... out the experiments, participated in the design ofthe study andthe drafting of this manuscript LA designed the vectors, conceived the experiments and drafted the manuscript Both authors read and ... contributes to the neuroprotective activity ofthe CM from ∆RR-infected EOC2 and E0C20 cells To examine the effect of IL-10 on the neuroprotective capacity ofthe CM from ∆RR-infected EOC2 and EOC20 ... ∆RR-infected EOC2 and EOC20 cells To examine whether ∆RR infection induces the production of neuroprotective factors and verify the effect ofthe cell activation state on their production, EOC2 and EOC20...
... functions/states ofthe system given by the multiplication ofthe number of basis functions per atoms, N O andthe number of atoms in the system Nα The starting point of every TB model is the definition of ... dominates the gate capacitance, the performance ofthe NW FETs only depends on the degeneracy of E-k instead of effective mass [34] Based on the bandstructure calculations, the variations ofthe bandgap ... function of nanowire diameter for n-type and ptype Si and Ge with oxide thicknessof 1.6 nm (13a and 13b) and oxide thicknessof 0.5 nm (13c and 13d) The capacitance value degrades from the gate...
... mentioned The men, especially the husband andthe grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... denoting the objects covered by the scope ofthe notion expressed in the word, andthe significative function is the function of expressing the content ofthe respective notion The function of rendering ... difficult The oldest or the husband ofthe family sits at the head ofthe table and others sit in descending order according to age or wherever they like The meal starts when everyone has their own...
... “Introduction” states the rationale ofthe study, Semantics can be simply defined as the study of meaning It defines the aims, objectives andthe significance, presents the is central to the study of communication ... review ofthe research Chapter 3: “Methodology and Procedures” mentions the method and procedures ofthe research Chapter 4: “Findings and Discussions” is the main frame of need to understand semantics ... element ofthe meaning of a word; a description ofthe characteristic feature of what the word refers to E.g the sense of “grasshopper” is “an insect which can jump high the study, which describes and...
... recognition ofthe field Andthe findings of semantic aspects often borrow the WDBs for not only conveying the denotative as well as analysis of pragmatic aspects of these kinds of words will ... understand their cases of Secondly, English considers the WDB “owl” as the symbol meaning, it is important to consider them in their collocations From of “wisdom” on the basis of their experience and ... pragmatic features ofthe WDBs The finding ofthe pragmatic features ofthe WDBs leads both teachers and learners of study may be in one way or another beneficial to the language English and Vietnamese...
... the spectrophotometric methods Because the enzymatic activity of PRTFDC1 towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, ofthe activity of HPRT, the role ofthe PRTFDC1 ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH ofthe ribose is hydrogen bonded to the main chain andthe side chain of Asp142 (Fig 1C) Both hydroxyl groups ofthe ribose are involved in ... Asp142, 2¢ and 3¢OH ofthe ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate ofthe GMP is hydrogen bonded to main chain and side chain atoms of amino...
... position at the present day The present theories ofthe transmission of light and sound; ofthe production of winds, and sun-spots, andofthe method of development and dissemination of heat, are ... except in the direction of other spheres These theories throw new light upon the character and extent ofthe atmosphere ofthe moon and planets, andthe consequent availability of those and other ... intimate and inherent nature of those forces? Do they, or either of them, belong to the domain ofthe supernatural? Are they the products of some supreme force, or forces, heretofore unappreciated? The...
... regards as the equivalent of thc npper part of t h e Portland Beds of southern England If, with ARKELL (1946, pp 24-28), we place the Portland Beds in the upper part ofthe Lower Volgian, they, the ... whorls of Tollia pnyeri Bitween 360 and 370 m, on the same flank ofthe moontain, the writer found similar doggers and platy-weathering sandstones, which contained occasional exarnples of Surifes and ... but further than this I am not prepared to go The dip ofthe rocks exposed in the 17all~gsides is often vcry nearly 1v Stratigraphy and Anr~noniteFauna of East Greenland 13 the same as the gradient...
... cause of offence In these habits we resemble the Aborigines of our country They load their huge pipes with the dried leaves of this plant, and when lighted, they breathe the dark cloud of smoke ... men void of understanding; capable of soothing the sorrows ofthe afflicted, of healing the wounds ofthe spirit, and assuaging the anguish of a broken heart But how it fulfils these desirable indications, ... form or other, either to ease the pains of dyspepsia, to allay the horrors of tedium vitæ, or to drown the anguish of a guilty conscience And may not many of these patients say to those ofthe Faculty,...
... component to the model ofthe choice ofthe length of stay The decision depends on the value ofthe unobservable taste We can now construct the probability of observing a series of stay decisions ... using the maximum ofthe expected value ofthe two coin flips—$0.50— rather than the expected value ofthe maximum—$0.75.) This approximation resulted in a model that the computer hardware and software ... Comparing the Dynamic Retention Model andthe Annualized Cost of Leaving Family of Models 15 The key difference from the DRM is that the ACOL is computing the maximum ofthe expected values rather...
... characteristics ofthe Internet; , Ko and DIKo are defined as the average diameter, K, and DIK ofthe original networks and df , Kf and DIKf denote the diameter, K, and DIK after 10% ofthe nodes are ... meaningful The other metric, S, is defined as the ratio ofthe number of nodes in the giant connected component divided by the total number of nodes One might notice the different characteristics ofthe ... snapshots ofthe real Internet topology.1 On the other hand, [42], [43] have shown that the clustering coefficient ofthe Internet has been growing and that the average diameter ofthe Internet...
... understanding ofthe structure of both the Ab monomer and its various assemblies could help in the design of new therapeutic strategies targeted at preventing the formation or ameliorating the activity ... increases the cost ofthe purification, andthe require1276 ment for HPLC increases the length and complexity ofthe purification procedure Moreover, as with the studies by Lee et al [21] and Subramanian ... Subramanian and Shree [42], there was no rigorous assessment ofthe purity ofthe product or the correctness ofthe sequence In contrast, the purification protocol that we have developed is quick and...
... residues and hence does not conflict with the global interpretation ofthe data With the exclusion ofthe N-terminal octapeptidyl and C-terminal nonapeptidyl fragments of Glu17, Leu34 and Lys46, the ... Fig The localization ofthe experimental points in Fig along the correlation line is directly related to the distribution ofthe energy between the overall tumbling andthe internal mobility, and ... and Ala60–Gln67), together with those from Arg58 and Gln59 in the C-terminal end of helix III, are located apart from the major cluster, towards the lower intercept ofthe theoretical curve and...