... stimuli [11-13] However, in spite of the relevance of these reservoir cells in the control of viral persistence, the mechanisms responsible of apoptosis resistance of persistently-infected cells ... independent of the magnitude of viral replication Apoptosis resistance is independent of the magnitude of viral replication A) Jurkat and J1.1 cells were incubated in the presence or absence of 1000 ... experiments of apoptosis by Hoechst and APOBrDU DOC and GAR were responsible of experiments using Western blot analysis, and contributed to writing of the manuscript MB, RL and MS performed and interpreted...
Ngày tải lên: 13/08/2014, 06:20
... archives in the Netherlands, namely KITLV (The Royal Netherlands Institute of Southeast Asian and Caribbean Studies) in Leiden, The Wereldmuseum and The Netherlands Photo Museum in Rotterdam and the ... together different kinds of photographs (miscellaneous) that not fit into the themes of other albums The sizes of the photographs vary, and so the depicted subjects Based on the quality of the photographs, ... collections of different museums and archives in the Netherlands, namely, the Tropenmuseum of the Royal Tropical Institute (KIT) and The Print Room of the Rijksmuseum in Amsterdam; the Royal Netherlands...
Ngày tải lên: 14/05/2015, 10:07
Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... particular, the four-stranded b sheet formed by the aminoacid residues at the N- and C-termini of PR contribute close to 75% of the total Gibbs energy [15] The importance of this four-stranded b ... dimer (residues 1–5 and 95–99) Additional interactions include a complex salt bridge between D29 and R87 of one subunit and R8 of the other subunit Thermodynamic analyses of the dimeric PR molecule ... interactions in the dimer include interactions between the catalytic triad residues (D25-G27), I50 and G51 at the tip of the flaps, and the antiparallel b sheet formed by the four termini in the dimer...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... capacity and also modulating the catalytic properties of the enzyme [19] To extend the information about the role of the noncatalytic SBD regions and their effect on the C-terminal CD, we further ... showing a lack of interaction for the individual SBDs and also in the absence of the D(316–344) and D(495–535) regions of the D2 and D3 domains, respectively Kinetic parameters of co-purified recombinant ... that the N-terminal region of SSIII can interact with SSI [13] The possible regulatory role of this protein makes this isoform a potential target for the manipulation of the level and quality of...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo y học: "Bench-to-bedside review: Biotrauma and modulation of the innate immune response" pps
... clinical trial of protective ventilation strategy Further evidence is required to determine whether the soluble Fas ligand actually originated in the lungs Irrespective of the source, these findings ... mg/kg) and did not result in overt ALI before initiation of the ventilation protocol; and the mechanical ventilation protocol used levels of Vt that did not lead to disruption of the epithelial ... dissemination of bacteria and infection Schortgen and coworkers [53] evaluated the effect of Vt reduction and alveolar recruitment on systemic and contralateral dissemination of bacteria and inflammation...
Ngày tải lên: 12/08/2014, 20:21
Báo cáo sinh học: "∆RR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis" docx
... out the experiments, participated in the design of the study and the drafting of this manuscript LA designed the vectors, conceived the experiments and drafted the manuscript Both authors read and ... contributes to the neuroprotective activity of the CM from ∆RR-infected EOC2 and E0C20 cells To examine the effect of IL-10 on the neuroprotective capacity of the CM from ∆RR-infected EOC2 and EOC20 ... ∆RR-infected EOC2 and EOC20 cells To examine whether ∆RR infection induces the production of neuroprotective factors and verify the effect of the cell activation state on their production, EOC2 and EOC20...
Ngày tải lên: 14/08/2014, 19:22
modulation of the structure and dynamics of acyl-acyl carrier protein by fatty acids of different length
Ngày tải lên: 14/11/2014, 10:21
Computational study of shape, orientation and dimensional effects on the performance of nanowire fets
... functions/states of the system given by the multiplication of the number of basis functions per atoms, N O and the number of atoms in the system Nα The starting point of every TB model is the definition of ... dominates the gate capacitance, the performance of the NW FETs only depends on the degeneracy of E-k instead of effective mass [34] Based on the bandstructure calculations, the variations of the bandgap ... function of nanowire diameter for n-type and ptype Si and Ge with oxide thickness of 1.6 nm (13a and 13b) and oxide thickness of 0.5 nm (13c and 13d) The capacitance value degrades from the gate...
Ngày tải lên: 03/10/2015, 21:56
Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.
... mentioned The men, especially the husband and the grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... denoting the objects covered by the scope of the notion expressed in the word, and the significative function is the function of expressing the content of the respective notion The function of rendering ... difficult The oldest or the husband of the family sits at the head of the table and others sit in descending order according to age or wherever they like The meal starts when everyone has their own...
Ngày tải lên: 15/04/2013, 15:11
A study of semantic and pragmatic features of the adjective warm and its vietnamese equivalents
... “Introduction” states the rationale of the study, Semantics can be simply defined as the study of meaning It defines the aims, objectives and the significance, presents the is central to the study of communication ... review of the research Chapter 3: “Methodology and Procedures” mentions the method and procedures of the research Chapter 4: “Findings and Discussions” is the main frame of need to understand semantics ... element of the meaning of a word; a description of the characteristic feature of what the word refers to E.g the sense of “grasshopper” is “an insect which can jump high the study, which describes and...
Ngày tải lên: 26/11/2013, 13:21
A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese
... recognition of the field And the findings of semantic aspects often borrow the WDBs for not only conveying the denotative as well as analysis of pragmatic aspects of these kinds of words will ... understand their cases of Secondly, English considers the WDB “owl” as the symbol meaning, it is important to consider them in their collocations From of “wisdom” on the basis of their experience and ... pragmatic features of the WDBs The finding of the pragmatic features of the WDBs leads both teachers and learners of study may be in one way or another beneficial to the language English and Vietnamese...
Ngày tải lên: 26/11/2013, 13:30
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... the spectrophotometric methods Because the enzymatic activity of PRTFDC1 towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, of the activity of HPRT, the role of the PRTFDC1 ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in ... Asp142, 2¢ and 3¢OH of the ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate of the GMP is hydrogen bonded to main chain and side chain atoms of amino...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu NEW AND ORIGINAL THEORIES OF THE GREAT PHYSICAL FORCES doc
... position at the present day The present theories of the transmission of light and sound; of the production of winds, and sun-spots, and of the method of development and dissemination of heat, are ... except in the direction of other spheres These theories throw new light upon the character and extent of the atmosphere of the moon and planets, and the consequent availability of those and other ... intimate and inherent nature of those forces? Do they, or either of them, belong to the domain of the supernatural? Are they the products of some supreme force, or forces, heretofore unappreciated? The...
Ngày tải lên: 17/02/2014, 01:20
Tài liệu STRATIGRAPHY AND AMMONITE FAUNA OF THE VOLGIAN AND BERRIASIAN ROCKS OF EAST GREENLAND ppt
... regards as the equivalent of thc npper part of t h e Portland Beds of southern England If, with ARKELL (1946, pp 24-28), we place the Portland Beds in the upper part of the Lower Volgian, they, the ... whorls of Tollia pnyeri Bitween 360 and 370 m, on the same flank of the moontain, the writer found similar doggers and platy-weathering sandstones, which contained occasional exarnples of Surifes and ... but further than this I am not prepared to go The dip of the rocks exposed in the 17all~gsides is often vcry nearly 1v Stratigraphy and Anr~noniteFauna of East Greenland 13 the same as the gradient...
Ngày tải lên: 17/02/2014, 20:20
Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx
... cause of offence In these habits we resemble the Aborigines of our country They load their huge pipes with the dried leaves of this plant, and when lighted, they breathe the dark cloud of smoke ... men void of understanding; capable of soothing the sorrows of the afflicted, of healing the wounds of the spirit, and assuaging the anguish of a broken heart But how it fulfils these desirable indications, ... form or other, either to ease the pains of dyspepsia, to allay the horrors of tedium vitæ, or to drown the anguish of a guilty conscience And may not many of these patients say to those of the Faculty,...
Ngày tải lên: 17/02/2014, 22:20
Tài liệu The Dynamic Retention Model for Air Force Officers- New Estimates and Policy Simulations of the Aviator Continuation Pay Program doc
... component to the model of the choice of the length of stay The decision depends on the value of the unobservable taste We can now construct the probability of observing a series of stay decisions ... using the maximum of the expected value of the two coin flips—$0.50— rather than the expected value of the maximum—$0.75.) This approximation resulted in a model that the computer hardware and software ... Comparing the Dynamic Retention Model and the Annualized Cost of Leaving Family of Models 15 The key difference from the DRM is that the ACOL is computing the maximum of the expected values rather...
Ngày tải lên: 17/02/2014, 23:20
Tài liệu Static and Dynamic Analysis of the Internet’s Susceptibility to Faults and Attacks docx
... characteristics of the Internet; , Ko and DIKo are defined as the average diameter, K, and DIK of the original networks and df , Kf and DIKf denote the diameter, K, and DIK after 10% of the nodes are ... meaningful The other metric, S, is defined as the ratio of the number of nodes in the giant connected component divided by the total number of nodes One might notice the different characteristics of the ... snapshots of the real Internet topology.1 On the other hand, [42], [43] have shown that the clustering coefficient of the Internet has been growing and that the average diameter of the Internet...
Ngày tải lên: 18/02/2014, 01:20
Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf
... understanding of the structure of both the Ab monomer and its various assemblies could help in the design of new therapeutic strategies targeted at preventing the formation or ameliorating the activity ... increases the cost of the purification, and the require1276 ment for HPLC increases the length and complexity of the purification procedure Moreover, as with the studies by Lee et al [21] and Subramanian ... Subramanian and Shree [42], there was no rigorous assessment of the purity of the product or the correctness of the sequence In contrast, the purification protocol that we have developed is quick and...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... residues and hence does not conflict with the global interpretation of the data With the exclusion of the N-terminal octapeptidyl and C-terminal nonapeptidyl fragments of Glu17, Leu34 and Lys46, the ... Fig The localization of the experimental points in Fig along the correlation line is directly related to the distribution of the energy between the overall tumbling and the internal mobility, and ... and Ala60–Gln67), together with those from Arg58 and Gln59 in the C-terminal end of helix III, are located apart from the major cluster, towards the lower intercept of the theoretical curve and...
Ngày tải lên: 18/02/2014, 16:20