... female, and 16 male (71 and 29%, respectively) Thirty three subjects were randomized to receive risperidone, and 23 received paroxetine (57% and 43%, respectively) In order to test whether the observed ... depressive symptoms than in subjects with fewer depressive symptoms Previous studies of risperidone in anxiety disorders have focused on generalized anxiety disorder, obsessive-compulsive disorder, ... reported that adjunctive risperidone was more effective than placebo in subjects suffering with generalized anxiety disorder Adjunctive risperidone was also reported to be effective in reducing symptoms...
Ngày tải lên: 11/08/2014, 17:20
... at what I saw a To turn b on c was d at > a I would rather live on a farm than to live in a city a would rather b live c on d to live > d The school library is free and open for all the pupils ... is divided into five parts and each of these three sections a have b has c will have d had > b 262 Norman E Borlaug was the first agricultural scientist to the Nobel Peace Prize a receive ... to > c 58 If you make a five-days trip across the Atlantic Ocean, your ship enters a different time zone everyday a make b five-days c enters d zone > b 59 When he arrived at the furniture shop,...
Ngày tải lên: 05/11/2012, 09:18
Test yourself A and Test 1(Kiều Tính)
... parents like to live in a house because they want to lead independent lives A printing B guest C nursing D private The Americans may be much more concerned physical attractiveness than ... recreation have received more public attention, such as skiing, snowboarding, skydiving, hang-gliding, rock climbing, backpacking, and adventure tourism Some recreational activities are made illegal ... quality of life, health and wellness, and that the use of recreation as a diversion may have clinical applications to individuals with chronic pain and other health impairments In some cultures...
Ngày tải lên: 02/07/2013, 01:25
Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt
... transplanted MSCs [12,13] IL-10 is also a potential anti-fibrotic factor in the liver and kidney [14–16] In addition, the protective effect of MSCs against sepsis is dependent on IL-10, which is not directly ... culture conditions To further clarify the molecular mass range of important active factors in the MSCs-CM, the medium was divided into B Fig MSCs-CM inhibits cardiac fibroblast proliferation and collagen ... SD for h and detection of relative mRNA levels of IL-1b and TNF-a by real-time PCR *P < 0.05 and **P < 0.01 versus hypoxia ⁄ SD treatment group (D) A representative pattern of the nuclear translocation...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... activity Chitinolytic activity was detected, peaking h after inoculation (Fig 1) After h, chitinolytic activity declined, but still remained signicant We could not detect chitinolytic activity ... acid bacterium (LAB) Lactococcus lactis ssp lactis IL1403 LABs are Gram-positive, facultatively, anaerobic, fermentative bacteria that are of major importance in the food industry for the generation ... chitinases act processively, that is, they remain associated with one and the same polymer chain whilst cleaving off consecutive dimers (also called multiple attack mechanism [11]) Processivity is considered...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf
... is sensitive to b-hexosaminidase, giving rise to radioactive Gal, and identified as GlcNAcb1-3Gal The trisaccharide was mostly sensitive to b1,4galactosidase, giving rise to a disaccharide and a ... sensitive to b1,4galactosidase, giving rise to a disaccharide and a monosaccharide, and is thus identified as Galb14GlcNAcb1-3Gal, while the tetrasaccharide was sensitive to a1,3/4 fucosidase, giving ... b1,3Gal-T activity and sLea antigen synthesis in these cells In addition, T5AS clone became weakly positive to sLex, that instead is undetectable in BxPC3 cells, and remains negative to Lea, faintly...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx
... proliferator-activated receptor c coactivator-1a (PGC-1a) is the founding member of the family of transcriptional coactivators, including peroxisome proliferator-activated receptor c coactivator-1b ... with empty vectors (A) COX activity, CS activity and the ratio of COX activity to CS activity were determined 48 h after transfection (B) Protein levels of complex IV subunit were determined by ... cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis Cell 92, 829–839 Handschin C & Spiegelman BM (2006) Peroxisome proliferator-activated receptor gamma coactivator coactivators,...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot
... defective in protein A Strain 8325-4 with repaired defect in rsbU Mutant strain of SH1000 defective in protein A Mutant strain of SH1000 defective in FnBPs Mutant strain of SH1000 defective in ... FnBPs Mutant strain of P1 defective in protein A Mutant strain of P1 defective in FnBPs Mutant strain of P1 defective in FnBPs and protein A Mutant strain of P1 defective in FnBPs and protein A, ... fnbA+ Mutant strain of P1 defective in FnBPs and protein A, complemented with plasmid expressing fnbA+ lacking repeats and 10 Restriction-negative 8325-4 derivative Intermediate host for plasmid...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Coordination of three and four Cu(I) to the a- and b-domain of vertebrate Zn-metallothionein-1, respectively, induces significant structural changes doc
... A B equivalents Cu(I) 3000 equivalents Cu(I) 2000 1000 relative intensity 6000 4000 relative intensity 50 40 7000 5000 relative intensity 60 B Dolderer et al 5000 4000 3000 2000 1000 equivalents ... the backbone and all heavy atoms, respectively In the previous study on the Cd7 derivative, metal–sulphur connectivities were obtained using the NMR-active cadmium isotope 113Cd and added to H ... of the adomain, two positive dichroic bands developed at 248 and 300 nm, respectively, and one negative band at 275 nm The addition of Cu(I) to Zn3bMT-1 shifted the positive dichroic band at 248...
Ngày tải lên: 07/03/2014, 09:20
Báo cáo khoa học: Puroindoline-a and a1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells pptx
... (arrow), respectively a1-PTH forms ionic channels in giant liposomes Giant liposomes containing a1-PTH also produced excised patches with seals of high resistance Channel activity was found in ... corresponding to zero current were and )20 mV (arrow), respectively conductance channel formed by a1-PTH is an anionic channel The Ca2+ selectivity of the channels was nil Indeed, when the concentration ... channel activities exhibited by giant liposomes containing a1-PTH (A) Unitary current traces recorded in response to holding potentials varying from to ± 80 in steps of 40 mV (B) Representative current–voltage...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Mutual effects of proton and sodium chloride on oxygenation of liganded human hemoglobin Oxygen affinities of the a and b subunits potx
... recent study [17], having the individual parameters of bimolecular recombination (BR) for each subunit type within native HbA, it has been proposed that the relative O2 affinity for HbA subunits ... behavior of HbA oxygenation Taking advantage of the photosensitivity of the heme Fe–ligand bond [8–14], flash photolysis has been used extensively in kinetic studies of oxygenated hemoglobins Recently, ... different heterotropic effectors on the individual parameters of oxygenation for each subunit type within the tetrameric protein Recently [18], effects on the individual properties of the a and b subunits...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution ppt
... charges on SUMO-2 and SUMO-1 are shown Positively charged, negative charged and neutral polar residues are coloured blue, red and magenta, respectively, and nonpolar residues are shown in green ... 0.1 mm3 in (B) In (C) and (D) are representative electron density maps superimposed on the refined models of the two crystal forms I and II, respectively Both were contoured at 2.0 r levels using ... by Luzzati plots [23] The electron density maps in a representative region are ˚ shown in Fig 2C and D At 1.2 A resolution, individual atoms begin to appear as discrete spheres An overall ribbon...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf
... with and inhibit cPLA2-a activity [36–38] Studies also revealed that a specific peptide derived from the N-terminus of annexin I was able to inhibit phosphorylation and activation of cPLA2-a [39] ... Verkleij AJ (2000) Regulation of cytosolic phospholipase A(2) in a new perspective: recruitment of active monomers from an inactive clustered pool Biochemistry 39, 7847–7850 Sierra-Honigmann MR, Bradley ... Biotechnology (Santa Cruz, CA, USA) Mouse monoclonal antivimentin serum was obtained from Sigma (Poole, UK) Anti-caveolin sera were a gift from N M Hooper (University of Leeds, UK) Mouse monoclonal C4 actin...
Ngày tải lên: 16/03/2014, 18:20
The a and b adapters are used as priming sites for both amplification
... ingredients needed for a PCR reaction • PCR takes place in each of these beads individually, but all in parallel • This activity as a whole is emPCR Post emPCR • The micro-reactors are broken, and ... Sequencing • Utilizing the A adapter, a primer is added to the ssDNA • The beads are now loaded into individual wells created from finely packed and cut fiber-optics (PicoTiterPlate device) • The size ... added in a timed fashion (beginning with A, T, G, C with 10s between each nucleotide and a successive apyrase wash, followed by the next nucleotide.) • As a bi-product of incorporation, DNA polymerase...
Ngày tải lên: 19/03/2014, 22:32
Báo cáo khoa học: Unprecedented pathogen-inducible complex oxylipins from flax – linolipins A and B docx
... 13l-hydroperoxyoctadecadienoic acids as substrates for the formation of a divinyl ether derivative Biochim Biophys Acta 398, 1–9 22 Proteau PJ & Gerwick WH (1993) Divinyl ethers and hydroxy fatty acids from three species ... garlic (Allium sativum L.) bulbs: detection of the novel divinyl ether oxylipins FEBS Lett 371, 159–162 24 Grechkin AN & Hamberg M (1996) Divinyl ether synthase from garlic (Allium sativum L.) bulbs: ... novel unsaturated ether derivative isolated from homogenates of Solanum tuberosum tubers Biochem J 129, 743–753 20 Galliard T, Phillips DR & Frost DJ (1973) Novel divinyl ether fatty acids in...
Ngày tải lên: 23/03/2014, 05:22
Báo cáo khoa học: Expressed as the sole Hsp90 of yeast, the a and b isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90b generates sensitivity to the Hsp90 inhibitor radicicol pdf
... mitogen-activated protein (MAP) kinase [18] GR assays indicated that human Hsp90a and Hsp90b, as well as the native yeast Hsp90s, were all capable of activating GR in these strains (Fig 2) Active v-src ... constitutive ERK5 expression (pG1 and pG1-ERK5, respectively [18]), as well as a plasmid bearing the YIL117w-LacZ reporter gene [27], which monitors the activity of Rlm1p, a transcription factor activated ... efficient HSE2-lacZ activation by heat shock in cells expressing either the native yeast Hsp82 or Hsc82, or the human Hsp90a (PP30[pHSC82b], PP30[pHSP82], and PP30[hHsp90a], respectively), but only...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Identification of the N-termini of NADPH : protochlorophyllide oxidoreductase A and B from barley etioplasts (Hordeum vulgare L.) ppt
... N-terminal peptides decrease in intensity This could be indicative of a correspondingly lower concentration of 1078 these two alternative PORB proteins The reason for differential processing of ... 7, 642–654 37 Thompson JD, Higgins DG & Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties ... transit peptide of pPORA as recently proposed [22] Results Acetylation of the POR protein and selective isolation of the N-terminal peptide Proteins extracted from plant or animal tissue are well...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo khoa học: Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa ⁄ fa rats pptx
... the activities of phosphorylase and glycogen synthase as described in Experimental procedures (A) Phosphorylase activity assayed in the presence of AMP (B) Phosphorylase-a activity (C) Active glycogen ... indicative of a difference in coupling between glycogen synthase and phosphorylase-a Flux-control coefficients can be positive or negative, and values greater than unity are rare [37] and indicative ... associated with inactivation of phosphorylase and activation of glycogen synthase and translocation of these proteins [26–28] The expression of GL and PTG, but not R6, in rat liver in vivo is insulin-dependent...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: Molecular analysis of the interaction between cardosin A and phospholipase Da Identification of RGD/KGE sequences as binding motifs for C2 domains pdf
... and autoactivated at acidic pH [34] Activated samples were analyzed by SDS ⁄ PAGE, and native cardosin A (CA) was used as control The gel was stained with Coomassie Blue (B) After activation, recombinant ... recombinant cardosin A were autoactivated and assayed for activity as described by Castanheira et al [34] Binding assays In vitro interactions between native cardosin B, native cardosin A, recombinant ... coli and purified They were autoactivated at acidic pH as previously described [34], and full aspartic proteinase activity was measured for all enzymes The activated fractions are shown in Fig...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: Cloning of a rat gene encoding the histo-blood group A enzyme Tissue expression of the gene and of the A and B antigens potx
... range for adhesion of pathogens and the presence of protective antibodies mean that all individuals would not be equally sensitive to a given pathogen This would provide a mechanism of protection ... determining A activity whereas an alanine determines B activity A glycine is present at the homologous position in the rat sequence (position 263), suggesting a potential A enzyme activity In order ... or B antigens (Fig 3) A positive control cell line (MT-450) known to constitutively express both antigens indicated that the antibodies readily detected their respective epitopes when present [24]...
Ngày tải lên: 31/03/2014, 09:20