... in 12 PARKINSON S DISEASE AND PARKINSONISM PINK1 in Drosophila causes male sterility, muscle wasting, dopaminergic neuronal degeneration, and increased sensitivity to stressors (Clark et al., ... which slows or stops disease progression ACKNOWLEDGEMENT This study was supported by grants from the NIH/NINDS (1 RO1 NS045999-01), the Bendheim Parkinson s Disease Center, and the Morris and Alma ... GPi single units and EMG of PD patients undergoing stereotactic neurosurgery Analysis using short sliding windows shows that oscillatory activity in both GPi oscillatory units and muscles occurs...
Ngày tải lên: 14/02/2014, 17:20
... a Special Issue of the Journal of Neural Transmission Professor Carlsson, 2000 Nobel Laureate, spent significant time at the congress site and was often seen discussing topics of mutual interest ... presence of the classical signs of tremor, rigidity and akinesia varies with respect to disability – its presence and progress; hence the need to quantify this interaction of physical signs and ... is similar in spirit to PLS (partial least squares) In PLS the cross-covariance between two data sets (in this case EEG and EMG) is first computed and then SVD (singular value decomposition) is...
Ngày tải lên: 14/02/2014, 17:20
Tài liệu Alzheimer’s Disease and Other Dementias doc
... blood vessels that supply the heart muscle with oxygen and nutrients narrow These diseases can cause strokes and heart disease (heart attacks) in the elderly The most common causes of illness and ... Psychological Disorders Alzheimer s Disease and Other Dementias Psychological Disorders Addiction Alzheimer s Disease and Other Dementias Anxiety Disorders Child Abuse and Stress Disorders Depression ... feelings, vision problems, etc Degenerative diseases like Huntington s disease or other rare, usually genetically transmitted diseases may also cause dementia in adolescents This illness destroys...
Ngày tải lên: 14/02/2014, 18:20
Hirschsprung´s Disease and Allied Disorders pptx
... chapters “Histopathological Diagnosis and Differential Diagnosis of Hirschsprung s Disease , “Immunohistochemical Studies” and “Electron Microscopic Studies of Hirschsprung s Disease For reasons ... Malformations associated with Hirschsprung s Disease , “Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome”, “Degenerative Hollow Visceral Myopathy Mimicking Hirschsprung s Disease and “Diagnosis ... difficult and challenging conditions such as Hirschsprung s disease Dr Grosfeld, a prestigious professor of pediatric surgery, was invited to write on the historical perspective of Hirschsprung s disease, ...
Ngày tải lên: 05/03/2014, 22:21
PARKINSON''''S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN potx
... includes discussion of the roles of oxidative stress, mitochondrial dysfunction, and neurotoxins and addresses etiologic mechanisms that have received less publicity, such as possible autoimmune and ... paresis, however, has sinister implications; it is typical of certain multisystem cerebral disorders, such as progressive supranuclear palsy, variants of Niemann-Pick disease, and, sometimes, ... disorder is associated with other signs, such as parkinsonism or ataxia Most hyperkinetic disorders arise outside conscious awareness and are entirely involuntary Some, however, are responses...
Ngày tải lên: 05/03/2014, 23:20
LifeOut of Focus Alzheimer’s Disease and Related Disorders ppt
... blouse and kicking off her shoes, too It hurts to see your grandmother cry when she realizes she isn’t the same person she used to be It hurts to see her stare at a wall It hurts to witness the ... OF FOCUS: ALZHEIMER S DISEASE AND RELATED DISORDERS THE COST OF ALZHEIMER S DISEASE As you can imagine, Alzheimer s disease is very expensive The cost of medical care for its victims is only ... with Alzheimer s disease In the initial stages of the disease, close associates may observe that the victim seems forgetful and has problems concentrating The person is distracted easily from the...
Ngày tải lên: 05/03/2014, 23:20
PET in the Evaluation of Alzheimer’s Disease and Related Disorders docx
... regarding cognitive functioning Cognitive screening includes using validated screening instruments, such as the MMSE, and brief bedside assessments Cognitive screenings are usually sensitive to significant ... lost in familiar surroundings, the physician can assess visuoconstruction or the ability to copy and produce figures on demand, such as a cross, square, and cube The physician can also assess ... in the disease course Cognitive deficits are prominent and become more severe and global as AD progresses Behavioral and personality changes, including agitation, aggression, and psychosis, often...
Ngày tải lên: 05/03/2014, 23:20
Surgical Treatment of Parkinson’s Disease and Other Movement Disorders pot
... disorders, such as Parkinson s disease, or hyperkinetic disorders such as hemiballism or drug-induced dyskinesias This classification is Wichmann and Vitek clinically useful, but is of limited relevance ... patients with Parkinson 's disease (PD), Hemiballismus (HB), and dystonia (DYS) hypo- and hyperkinetic disorders Dystonia is not a homogeneous entity; it may result from genetic disorders, from ... and/ or striosomes have been less successful and failed to establish simple relations between striatal compartments and different subdivisions of the SNc in nonhuman primates (52,53,56) Ultrastructural...
Ngày tải lên: 05/03/2014, 23:20
Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study doc
... ratios (MRR, dots) with 95% confidence intervals (whiskers) for all causes, all cardiovascular disease, ischemic heart disease and cerebrovascular disease associated with NO2 concentrations at residences ... characteristics Previous studies of NO2 and mortality from cardiovascular disease and all causes have shown both stronger [3,8,14,30], similar [4,8,31,32] and weaker [2,8,9] associations than this study ... associations between the simple traffic indicators and mortality from cardiovascular disease and all causes (Additional file 7: Table S6 ) Thus, when NO2 and noise were assessed in state-of-the art exposure...
Ngày tải lên: 06/03/2014, 19:20
The Handbook of Alzheimer’s Disease and Other Dementias doc
... Alzheimer s disease and dementia will find this book of interest, including physicians, medical students, psychologists, scientists, graduate students, and allied health professionals including nurses, social ... diagnosed as not having the disease) , and what is meant by disease. ” As we go to press, AD remains a clinical diagnosis which for years has been based on criteria from the Diagnostic and Statistical ... when it can be misdiagnosed as depression This misdiagnosis is understandable since low mood and apathy frequently go hand in hand Apathy and depression nevertheless are separate phenomena with...
Ngày tải lên: 14/03/2014, 21:20
An Atlas of PARKINSON’S DISEASE AND RELATED DISORDERS pdf
... index ISBN 1-85070-943-2 Extrapyramidal disorders Atlases Parkinsonism Atlases Movement disorders Atlases I Title II Series [DNLM: Parkinson Disease atlases Basal Ganglia Diseases atlases Movement ... patients with Parkinson 's disease (Figure 2) Parkinson s disease Any discussion of the clinical characteristics of Parkinson 's disease must take into account the inaccuracies of clinical diagnosis ... abruptly with sustained postures at an earlier age Wilson s disease Wilson 's disease is inherited as an autosomalrecessive trait The prevalence of the condition is estimated to be 30 / 000 000 with...
Ngày tải lên: 14/03/2014, 22:20
An Illustrated Pocketbook of Parkinson''''s Disease and Related Disorders pot
... the small percentage of cases with isolated parkinsonism The good response to dopa, seen in a minority of cases, is seldom sustained In such cases, substitution of a dopaminergic agonist is usually ... increased in those with a history of herbicide or metal exposure A family history of Parkinson s disease is associated with an increased disease risk Both autosomal-dominant and autosomalrecessive ... PARKINSON S DISEASE Figure 16 Parkinson s disease: dystonic posturing of the big toe secondary to dopa therapy 15 16 AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 17 Parkinson s disease: ...
Ngày tải lên: 14/03/2014, 22:20
ALZHEIMER’S DISEASE AND RELATED DISORDERS ANNUAL doc
... Sensitivity 85% Specificity 86% Sensitivity 40% Specificity 90% Sensitivity 77% Specificity 93% Result Aβ42 and tau: Innogenetics Aβ42 and tau: inhouse methods Multicenter study Aβ42: in-house ... vs NAD/VAD: NINCDS–ADRDA FTLD: Neary NINCDS–ADRDA CERAD Sensitivity: 71–90% Specificity: 83–100% Sensitivity 72% Specificity 89% Sensitivity 94% Specificity VAD 48% Specificity DLB 67% Sensitivity ... criteria.17 The NINCDS/ADRDA (National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer s Disease and Related Disorders Association) criteria for AD have a high sensitivity...
Ngày tải lên: 28/03/2014, 22:21
báo cáo hóa học: " Gait dynamics in mouse models of Parkinson''''s disease and Huntington''''s disease" doc
... SOD1 G93A and wild-type control mice at age ~8 weeks, ~10 weeks, ~12 weeks, and ~13 weeks Discussion Gait disturbances are characteristic of Parkinson 's disease, Huntington 's disease, and amyotrophic ... Parkinson 's disease and Huntington 's disease Mov Disord 1998, 13:428-437 Blin O, Ferrandez AM, Serratrice G: Quantitative analysis of gait in Parkinson patients: increased variability of stride ... NeuroEngineering and Rehabilitation 2005, 2:20 Background Disturbances in gait are symptomatic of Parkinson 's disease (PD) and Huntington 's disease (HD) Gait abnormalities in PD include shortened stride...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo sinh học: "Mycobacterium avium subsp. paratuberculosis linked to Crohn''''s Disease and Paratuberculosis" pot
... involvement of MAP is suspected, in particular Crohn 's disease in humans Table 1: In vitro activity of several drugs against MAP strains Drugs (μg/ml) Strains STR CPX EMB DPS RIF RIB CLA ATCC ... Taylor J: Detection and verification of Mycobacterium avium subsp paratuberculosis in fresh ileocolonic mucosal biopsy specimens from individuals with and without Crohn 's disease J Clin Microbiol ... is in contrast with previous reports [9-11] A number of antimicrobial agents have been used to combat flare ups in Crohn 's Disease These have included Ciprofloxacin and metronidazole, used either...
Ngày tải lên: 08/08/2014, 19:20
Báo cáo khoa học: "ACTH-producing carcinoma of the pituitary with refractory Cushing''''s Disease and hepatic metastases: a case report and review of the literature" pptx
... pituitary Cushing 's disease The rates of cure and recurrence of Cushing 's disease, and the quality of life after transsphenoidal pituitary surgery are still being investigated In a single-institution ... diagnosis was just over weeks while the longest reported survival was 21 years [2] In the same series, survival was found to be associated with location of metastases; metastases outside the craniospinal ... single-institution series of 162 patients, Sonino et al [30] sought to characterize the risk factors and long-term outcomes associated with transsphenoidal surgery for pituitary-dependent Cushing 's disease Pituitary...
Ngày tải lên: 09/08/2014, 04:21