patient specific modeling of structure and function of cardiac cells

... would be lost with the onset of obesity and type diabetes Table Baseline characterization of male and female obese mice Values are expressed for 18–20-week-old male and female db ⁄ + versus db ... University of Cape Town’s Animal Research Ethics Committee, and the investigation conforms to the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health ... addition of 300 lm ADP to the electrode chamber To test the ability of mitochondria to withstand oxidative stress, mm ADP was added after state respiration, and the chamber was closed and sealed...

Ngày tải lên: 18/02/2014, 16:20

... Journal of Orthopaedic Surgery and Research 2011 6:4 Authors’ contributions TD has contributed to conception and design of the study, acquisition of data, analysis and interpretation of data, and ... HM, and YM performed part of literature review KM and KK performed part of acquisition of data YI participated in design and coordination and helped to draft the manuscript All authors read and ... Range of curvature in scoliosis patients The upper and lower end vertebrae were examined in scoliosis patients The median of the upper end was at T5 and the lower end at T12 All were instances of...

Ngày tải lên: 20/06/2014, 04:20

... Journal of Orthopaedic Surgery and Research 2011 6:4 Authors’ contributions TD has contributed to conception and design of the study, acquisition of data, analysis and interpretation of data, and ... HM, and YM performed part of literature review KM and KK performed part of acquisition of data YI participated in design and coordination and helped to draft the manuscript All authors read and ... Range of curvature in scoliosis patients The upper and lower end vertebrae were examined in scoliosis patients The median of the upper end was at T5 and the lower end at T12 All were instances of...

Ngày tải lên: 20/06/2014, 07:20

... packet to the destination and is often implemented using a timer The delay of utility-based routing is expected to be lower than that in OPPT and RAND routing Also, the number of packet forwarding ... values that work well for a large number of subject individuals and range of postures to be in between sec and 14 sec Figure shows the evolution of PLC βi, j (n) and HCQ ωi, j (n) with time The top ... link-specific and time-varying βi, j (n), on the other hand, is able to handle both situations well by mimicking the behavior of ω = 0.9 during the historically good-link situation and that of ω = 0.1...

Ngày tải lên: 21/06/2014, 11:20

... gain over the bandwidth of each bin, the shape of the cross-spectrum is determined solely by the frequency response of the analysis filters and Sss ( f ), the power spectral density of s(n) That ... integer, and let g (n) have a constant λ sample delay The delay difference between g (n) and c (n) is thus λ − The bandwidth of each bin is equal to fc = fs /K and so the magnitude of Sdk xk ... N (27) where the bandwidth 2b = MN/K Although not explicitly indicated in (27), the delays and are a function of the bin number, k The autocorrelation functions RXk Xk (m) and RDk Dk (m) can...

Ngày tải lên: 23/06/2014, 01:20

... rate of 24/ minute with a PEEP of 3.5 cmH2O was as effective at maintaining PO2 as a respiratory rate of 7/minute and a PEEP of 14 cmH2O In our HP/LP group, the respiratory rate was 20/ minute and ... manuscript drafting, data analysis and extensive editing GFN contributed to the design and development of the protocol, data analysis and interpretation, and writing of the manuscript Additional files ... image analysis software Alveolar stability was assessed by the percentage change in the area of individual alveoli from I to E (%I – EΔ) Randomization of alveoli for measurement of alveolar stability...

Ngày tải lên: 13/08/2014, 03:21

... positive staining cells in smooth muscle cells of portal vasculature, most spindle-shaped stromal cells and neural cells (Fig 1a) Cells in Glisson's capsule as well as all stromal cells around the ... changes or functional changes such as increased cell size, loss of lipid vacuoles and enhanced production of TGF-β and other substances may be helpful The absence of reactivity of portal MF and HSC ... caused by the intrinsic patient material variability regarding time of postmortal sampling and fixation, the age of the paraffin blocks, and age, sex and breed variation of the animals However,...

Ngày tải lên: 13/08/2014, 13:20

... 0.05 midazolam, propofol, and methohexitone vs etomidate and s(+)-ketamine; $P < 0.05 propofol vs midazolam and methohexitone Data are the means ± standard error of the mean Page of (page number ... phases of contraction and relaxation [7-11] Almost one-fifth of all septic patients with refractory hypotension die because of a low cardiac output deriving from this severe myocardial dysfunction ... control; #P < 0.05 midazolam and propofol vs etomidate and methohexitone $P < 0.05 s(+)-ketamine vs propofol, midazolam, and methohexitone Data are the means ± standard error of the mean Discussion...

Ngày tải lên: 13/08/2014, 19:20

... those most in demand are oil of roses, oil of sandal-wood, an essence from the blossom of a species of mimosa, essence of musk, and the oil of cloves The women have a peculiar method of scenting their ... did, and at the end of a couple of hours both the dandy and his pomade were exhausted The poor fellow had to return to his friends with the total loss of personal appearance and half a pound of ... was a succession of gullies and ravines, of landslips and watercourses The entire hollow, of miles in width, had evidently been the work of the river How many ages had the rains and the stream...

Ngày tải lên: 15/02/2014, 09:20

... neurological and cardiac abnormalities, are observed [2637] As yet, there is no clear understanding of the relationship between genotype and phenotype, although functional evaluations of most of the ... defects in the craniofacial bones, loss of tooth enamel, and abnormal soft tissue separation of two or three digits [24,25] Depending on the particular Cx43 mutation, a wide range of other abnormalities, ... Expression of Cx43eYFP constructs in MDCK cells (A) Surface and total protein were isolated by biotinylation and analyzed by western blot Using Cx43 and GFP antibodies to conrm proper translation of...

Ngày tải lên: 23/03/2014, 04:20

... plough; of the lure of the waterways and roads where I have followed the boats and the trails of French voyageurs and coureurs de bois; and of the possessing interest of the epic story of the ... times than all the lands of the Seine and the Rhone and the Loire, and richer many times than the land of spices to which the falls of Lachine, "the greatest and swiftest fall of water that any ... those midway of the valley it came out of the mystery of the Land of Frosts and passed silently on, or, in places, complainingly on, to the mystery of the Land of the Sun, into neither of which dared...

Ngày tải lên: 31/03/2014, 13:20

... components of these child-patients and how to measure them, showing sensitivity to the continuous and rapid cognitive and emotional development of children, getting information from the patient and ... PedsQL™ Generic Core Scales and for the Cardiac Module across all ages of the patient and comparison groups are presented in Tables and Table The recommended standard of 0.70 for group comparison ... Psychosocial functioning Emotional functioning Social functioning School functioning Parent Proxyreport Psychosocial functioning N = Number of valid cases; S.D = Standard deviation; *Difference between cardiac...

Ngày tải lên: 18/06/2014, 19:20

... (CPE) in Vero cells consisted of the formation of granular-appearing cytoplasm with vacuolization (small vacuoles), followed by rounding of the cells and detachment, and rare formation of small stellate ... brain and lung tissues of raccoons examined in year 2001 than those of years 1998 and 2000 Of note, small and large (multinucleated) syncytia were present in the central nervous system and (Fig ... 2000, and 2001 but not in 1999, 2002, and 2003 A total of 9/25 (36%) of the animals submitted for necropsy in 1998 and 1/14 (7%) in 2000 had lesions consistent with CDV infection The number of animals...

Ngày tải lên: 18/06/2014, 22:20

... Snaith and Zigmond's [29] interpretation of HADS-A and HADSD scores of or over, approximately one-third of the patients screened positive for anxiety (32%) and/ or depression (35%) The results of ... for screening and case detection utility and accuracy [16] The present study was designed to examine the underlying factor structure of the Chinese version of the HADS in a mainland Mandarin-speaking ... Chinese version of HADS to patients for self-completion Demographic data and medical history were also obtained from patients and medical charts Participants One hundred and sixty patients with...

Ngày tải lên: 20/06/2014, 15:20

... physical functioning; RL: role limitation; SF: social functioning; PN: pain; MH: mental health; VT: vitality Figure Bland-Altman plot of EQ-5D and SF-6D Bland-Altman plot of EQ-5D and SF-6D Page of ... 280 patients [14,15] The study protocols of both trials required completion of both the EQ-5D and the SF-36 pre- and month post-intervention, with follow-up until year post-intervention [14] Patients ... study group of 561 patients consisted of mostly males (70.4%); the mean age was 60.2 years (sd 9.3) Domain comparison The EQ-5D and the SF-6D both include pain and mental health (anxiety and depression)...

Ngày tải lên: 20/06/2014, 15:20

... multiple time points on patients participating in randomised clinical trials [5,6,8,16], and cohort study [17] The studies covered diagnosis of cardiac disease and interventions in patients ranging ... wide range of problems in a given domain, corresponding to widely different levels of HRQoL A 5-level version of the EQ-5D has been created and piloted and shows evidence of feasibility and greater ... stage and cardiac outcome measures for a group of cardiac patients that performed better in predicting the EQ-5D index for values above 0.4, and less well for values below Table 7: Performance of...

Ngày tải lên: 20/06/2014, 16:20

... obtained by Lacey and Philipp [4], Ibragimov and Lifshits [5], Miao [6], Berkes and Cs´ ki [7], H¨ rmann [8], Wu [9, 10], and Ye and Wu [11] Huang and Zhang [12] and Zhang a o and Yang [13] obtained ... sums of random variables in the domain of attraction of the normal law Qunying Wu1,2 College of Science, Guilin University of Technology, Guilin 541004, P R China Guangxi Key Laboratory of Spatial ... Innovation in the Construction of Talent Highlands in Guangxi Institutions of Higher Learning ([2011]47), and the support program of Key Laboratory of Spatial Information and Geomatics (1103108-08)...

Ngày tải lên: 20/06/2014, 21:20

... set of rd-continuous functions, while R denotes the set of all regressive and rd-continuous functions, and R+ = {f |f ∈ R, + μ(t)f (t) > 0, ∀t ∈ T} Definition 1.4: For some t Î T, and a function ... Foundation of China (11026047 and 10571110), Natural Science Foundation of Shandong Province (ZR2009AM011, ZR2010AQ026, and ZR2010AZ003) (China) and Specialized Research Fund for the Doctoral Program of ... (23) Feng et al Journal of Inequalities and Applications 2011, 2011:29 http://www.journalofinequalitiesandapplications.com/content/2011/1/29 Page of 14 Combining (17), (21), and (23), we obtain t...

Ngày tải lên: 21/06/2014, 01:20