patient specific modeling for critical care

... University of Cape Town’s Animal Research Ethics Committee, and the investigation conforms to the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health ... substrate for the generation of ATP as compared to fatty acids Also, fatty acid-mediated uncoupling of mitochondrial oxidative phosphorylation may result in diminished mitochondrial ATP production for ... functional analyses were only performed using fatty acids as substrate Additional studies measuring mitochondrial respiratory function using a more representative substrate for glucose oxidation should...

Ngày tải lên: 18/02/2014, 16:20

... used for statistical analysis Statistical methods included the Kruskal-Wallis test Results Thoracic curvature in scoliosis patient We assessed the side curve patterns of scoliosis patients before ... correlation coefficient for the intraobserver reliability of the Cobb angle measurements using chest radiograph was 0.82 for observer 1, 0.61 for observer 2, and 0.79 for observer (Table 1) The ... condition or for check up For normal spinal observations, we used patients without obvious chest and spinal diseases as determined by chest radiographs because the literature suggests that patients...

Ngày tải lên: 20/06/2014, 04:20

... used for statistical analysis Statistical methods included the Kruskal-Wallis test Results Thoracic curvature in scoliosis patient We assessed the side curve patterns of scoliosis patients before ... correlation coefficient for the intraobserver reliability of the Cobb angle measurements using chest radiograph was 0.82 for observer 1, 0.61 for observer 2, and 0.79 for observer (Table 1) The ... condition or for check up For normal spinal observations, we used patients without obvious chest and spinal diseases as determined by chest radiographs because the literature suggests that patients...

Ngày tải lên: 20/06/2014, 07:20

... utility information for all neighbors in the network Therefore, for large networks, maintaining utility information for every node can create significant scalability concerns However, for small ... export Model performance Comparative performance evaluation Prototype WBAN Experimental delay performance of DTN routing protocols Figure 4: Topology export for offline and model performance Time ... Example evolution of the forwarding matrix for a time-varying topology forwarded using the RAND protocol, however, can suffer from a large number of unnecessary forwarding before it is delivered at...

Ngày tải lên: 21/06/2014, 11:20

... filterbank architecture achieves the worst possible delay performance; and third, simple closed-form expressions can be obtained for its performance If the filterbank satisfies the perfect reconstruction ... can achieve the performance of a FIR filter For instance, if Nh = RK = RMI, where I is the oversampling factor, then even as K → ∞, L → RI There is a need to determine guidelines for the choice of ... FIR filter Consequently, we first obtain a general expression for the performance of an optimal FIR equaliser This will also be useful for the purpose of comparison between the FIR and the filterbank...

Ngày tải lên: 23/06/2014, 01:20

... null hypothesis being true was less than 5% (P < 0.05) Page of (page number not for citation purposes) Critical Care Vol 11 No Pavone et al Table Hemodynamic and pulmonary parameters Baseline ... study were performed in accordance with the National Institutes of Health guidelines for the use of experimental animals in research The protocol was approved by the Committee for the Humane ... inflammatory cells in the vascular compartment) Bar = 50 μm Page of (page number not for citation purposes) Critical Care Vol 11 No Pavone et al Previous work has demonstrated that normal alveoli not...

Ngày tải lên: 13/08/2014, 03:21

... 1:40 1:300 1:50 1:100 1:50 1:150 formalin formalin formalin frozen formalin frozen formalin frozen formalin M0635 M0776 MU074-UC SY38 V9 Page of (page number not for citation purposes) Comparative ... pure HM20 h at -45°C Polymerisation was performed for 36 h at 45°C, then temperature was raised in 5°C-steps for 13 h up to 20°C Temperature stayed 20°C for 150 h all under UV-light After ultrathin ... muscle actin (HHF35) The chance of formalin-induced epitope masking was regarded smaller by use of two different monoclonal antibodies for the same peptide Therefore, both markers were investigated...

Ngày tải lên: 13/08/2014, 13:20

... intensive care patients needing mechanical ventilation Intensive Care Med 2005, 31:388-392 Ray DC, McKeown DW: Effect of induction agent on vasopressor and steroid use, and outcome in patients ... this severe myocardial dysfunction It is, therefore, the everyday clinical challenge of each intensive care unit physician to sufficiently treat septic patients without further compromising the already ... to × 10-6 M for any induction agent At higher concentrations, heart rate was significantly suppressed at × 10-4 M for propofol (maximum decrease: -29 ± 4%) and at × 10-5 to × 10-4 M for midazolam...

Ngày tải lên: 13/08/2014, 19:20

... gone—The Bari chief's advice—Hoping for the best—Ho for Central Africa! CHAPTER XV CHAPTER XV A start made at last—A forced march—Lightening the ship—Waiting for the caravan—Success hangs in the ... therefore became his guests in a most comfortable house for some days Here we discharged our camels, as our Turk, Hadji Achmet's, service ended at this point, and proceeded to start afresh for ... Mats for his tent, ropes manufactured with the hair of his goats and camels, pots for carrying fat, water-jars and earthenware pots or gourd-shells for containing milk, leather water-skins for...

Ngày tải lên: 15/02/2014, 09:20

... (indicated by the arrow in the WT image) formed at points of cellcell contact in all mutants with the same frequency and morphology as WT except for F52dup, which formed plaques much less frequently ... at time for each cell line The Y286A mutation slightly impaired degradation of Cx43eYFP from the surface compared to WT For each cell type, at least three independent experiments were performed ... we performed confocal experiments in the absence of sodium butyrate pre-incubation and found similar distributions between the apical and basolateral surface for all constructs We then performed...

Ngày tải lên: 23/03/2014, 04:20

... the materials for a vessel, which he purposed building for the Mississippi waters, stayed for the rest of the winter, building for shelter and protection a fort which he named Fort Crèvecoeur, ... garrison Fort Frontenac (on the north shore of Ontario) and to gather about it a French colony For two years he labors there, bringing a hundred acres of sunlight into the forests, building ships for ... the Acadian Forest," where he was lost for sixteen days and subsisted on berries and wild fruits; there was the ravage of the relentless maladie de terre, scurvy, for which Cartier's specific could...

Ngày tải lên: 31/03/2014, 13:20

... Process for Patient- Reported Outcomes (PRO) Measures: Report of ISPOR Task Force for Translation and Cultural Adaptation Value in Health 2005, 8:94-104 48 Cohen J: Statistical Power Analysis for ... missing value percentages for the total cardiac module decrease from 15.0% to 5.4% for child self-report, and from 14.6% to 4.8% for parent proxy-report The high proportion of patients without surgical ... subscales for child self- and parent proxy-reports (Table 3.) Cronbach’s coefficient a estimates for the PedsQL™ Generic Core Scales and for the Cardiac Module across all ages of the patient and...

Ngày tải lên: 18/06/2014, 19:20

... Cook County for assisting with sample acquisition Andrea Guido provided excellent technical assistance We thank Dr K MacClatchey for critical review of this manuscript Partial funding for necropsy ... H-gene RT-PCR amplicons For CDV-2676, shown are the 1104 bp product (lane 1) using primers CDV-HforD and CDV-Hrev75, and the 1026 bo product (lane 2) using primers CDVH-forB and CDV-HrevC (29) ... CA) For the American CDV strains of this work, many RT-PCR primers based on the sequence of American CDV isolate A75/17 (GenBank No AF164967) were more effective than primers described for foreign...

Ngày tải lên: 18/06/2014, 22:20

... identical values for both models, was highly acceptable by conventional model-fit criteria [3033] Discussion Procedure The first author administered the Chinese version of HADS to patients for self-completion ... obtained from patients and medical charts Participants One hundred and sixty patients with CHD were initially enrolled into the study of which 154 completed the questionnaires The patients ranged ... study, performed the statistical analysis and assisted in the drafting of the manuscript Acknowledgements All the authors would like to thanks the patients who took part in the study for their...

Ngày tải lên: 20/06/2014, 15:20

... Stenting and Off-Pump Bypass Surgery in Patients Referred for Angioplasty Circulation 2003, 108:2870-2876 Dolan P: Modeling valuations for EuroQol health states Med Care 1997, 35:1095-1108 Essink-Bot ... seven patient groups, Brazier and coworkers found overall similar mean scores for the two measures in patients with mild diseases [24], but baseline values clearly differ in more severe patients ... baseline (%)# p-value for change in PTCA* p-value for change in offpump CABG*¶ SF-6D ceiling effect at baseline (%)# p-value for change in PTCA* p-value for change in offpump CABG*¶ pain anxiety/ depression...

Ngày tải lên: 20/06/2014, 15:20

... the minimal important difference for the EQ-5D index [22,23] The RMSEs were also higher for EQ-5D

Ngày tải lên: 20/06/2014, 16:20

... o(xα−2 l(x)) for α > Lemma 2.2 such that Let {ξ, ξn }n∈N be a sequence of uniformly bounded random variables If exist constants c > and δ > |Eξk ξ j | ≤ c then lim n→∞ Dn k j δ , for ≤ k < j, ... definition of η, thus for any ε > 0, we have ∞ ∞ k=1 ∞ ET nk ≤ c P(|T nk | > ε) ≤ c k=1 k=1 < ∞ k(1−η)(1+ε2 ) By the Borel-Cantelli lemma, T nk → a.s Now for nk < n ≤ nk+1 , by |ξk | ≤ c for any k, |T ... s ≥ b + 1, l(s) ≤ j s2 for j ≥ By the definition of η j , we have jl(η j ) ≤ η2 and jl(η j − ε) > (η j − ε)2 for any ε > It implies that j nl(ηn ) ∼ η2 , as n → ∞ n (13) For every ≤ i ≤ n, let...

Ngày tải lên: 20/06/2014, 21:20

... (t)Δt = 0, if f(t) ≥ for all a ≤ t ≤ b, then ab f (t)Δt ≥ For more details about the calculus of time scales, we advise to refer to [14] Main results In the rest of this paper, for the sake of convenience, ... (China) and Specialized Research Fund for the Doctoral Program of Higher Education (20103705 110003)(China) The authors thank the referees very much for their careful comments and valuable suggestions ... ∀t ∈ T} Definition 1.4: For some t Î T, and a function f Î (T, R), the delta derivative of f at t is denoted by fΔ(t) (provided it exists) with the property such that for every ε > 0, there exists...

Ngày tải lên: 21/06/2014, 01:20