pathogenesis diagnosis and therapy
báo cáo hóa học:" Mucins in ovarian cancer diagnosis and therapy" ppt
Ngày tải lên :
20/06/2014, 07:20
... (radioimmunotherapy) while sparing normal cells [8284] At present, MUC1 and MUC16 are the best and only characterized mucins and monoclonal antibodies against MUC1 and MUC16 are under preclinical and ... use of mucins as targets for radioimmunodiagnosis and radioimmunotherapy is also being explored and appears to be a potential approach for the diagnosis and treatment of ovarian tumors which overexpress ... serine, threonine, and proline in their backbone Serine and threonine are sites for O- and N-glycosylation Presence of the tandem repeat domain which varies in number, length and O-glycosylation...
- 9
- 387
- 1
báo cáo khoa học: "Pathogenesis, diagnosis and management of primary melanoma of the colon" doc
Ngày tải lên :
09/08/2014, 01:24
... melanomas that have not disseminated at the time of diagnosis This may be followed by postoperative radiation therapy, chemotherapy and immunotherapy for any residual disease or nodal involvement ... at least year months Mandot et al [8] 2006 62, F Right colon n/a + - n/a Brain metastases found at the time of diagnosis; managed with steroids, temozolamide and radiation therapy Expired within ... abdominal pain (20%) and weight loss (16%) [17] Figure shows a comparison of the signs and symptoms seen in primary and metastatic colonic melanoma Abdominal pain (58%) and weight loss (50%)...
- 9
- 327
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 1 doc
Ngày tải lên :
12/08/2014, 05:21
... Pediatric Epilepsy Diagnosis and Therapy Third Edition Pediatric Epilepsy Diagnosis and Therapy Third Edition EDITORS JOHN M PELLOCK, MD Chairman, Division ... Brain: Cells, Synapses, and Circuits Libor Velíšek and Solomon L Moshé Ion Channels, Membranes, and Molecules in Epilepsy and Neuronal Excitability Laxmikant S Deshpande and Robert J DeLorenzo ... D Bourgeois and Raman Sankar 40 ACTH and Steroids Rajesh RamachandranNair and O Carter Snead, III 543 41 Benzodiazepines Kevin Farrell and Aspasia Michoulas 557 42 Carbamazepine and Oxcarbazepine...
- 92
- 287
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 4 pot
Ngày tải lên :
12/08/2014, 05:21
... Paediatr Scand 1960; 49:572–582 Druckman R, Chao D Massive spasms in infancy and childhood Epilepsia 1955; 4:61–72 Gibbs EL, Fleming MM, Gibbs FA Diagnosis and prognosis of hypsarrythmia and infantile ... marked and rapid progress in the understanding of the cellular mechanisms producing SMEI, there is thus still ample room for further research Diagnostic Evaluation and Differential Diagnosis The diagnosis ... and adult patients with SMEI sleep without soft cushions, and we also recommend that febrile episodes be treated as early as possible Course and Prognosis Introduction and Definition SMEI stands...
- 92
- 251
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 5 docx
Ngày tải lên :
12/08/2014, 05:21
... motor and hand skills and loss of communication and cognitive functions between and 30 months Of particular significance is the loss of acquired speech Deceleration of head growth, stereotypic hand-wringing ... anticonvulsant and antiepileptogenic properties, and it may normalize EEGs It is well known that carbamazepine may worsen the generalized epilepsies and may even worsen focal spike -and- wave discharges and ... Lennox-Gastaut type and are less discrete in time, longer, and with slower and more polymorphic spike-wave complexes on EEG Absence seizures are the defining and predominant seizure type in CAE and juvenile...
- 92
- 368
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 6 ppt
Ngày tải lên :
12/08/2014, 05:21
... the concept of monotherapy and sequential monotherapy gained wide acceptance in the late 1970s and early 1980s, because the frequent negative impact of polytherapy on the number and intensity of ... antiepileptic and neurotoxic interactions between many of 32 • COMBINATION DRUG THERAPY: MONOTHERAPY VERSUS POLYTHERAPY the established and newer AEDs, including interactions between drugs and their ... neonates and small infants, is mandatory Optimal oxygenation and expectant observation and treatment for hyperthermia and other medical complications lead directly to a lessening of morbidity and...
- 92
- 223
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 7 pps
Ngày tải lên :
12/08/2014, 05:21
... DRUGS AND KETOGENIC DIET 40 ACTH and Steroids Rajesh RamachandranNair O Carter Snead, III he efficacy of adrenocorticotropin (ACTH) therapy in childhood seizures was first observed by Klein and ... seizures, and normalization of the EEG in three of three children with Landau-Kleffner syndrome (74) Four children with Landau-Kleffner syndrome received early and prolonged ACTH or corticosteroid therapy, ... aphasia and improvement of seizure control Three to six years after discontinuation of hormone therapy the children were off medication and free from seizures and language disability Sinclair and...
- 92
- 268
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 9 pptx
Ngày tải lên :
12/08/2014, 05:21
... (2.3%) had to discontinue ZNS therapy (sleeplessness and increased seizures, failure to gain weight, and behavioral changes in one patient each) Add-on Polytherapy Kim and colleagues have reported ... Biotransformation, Pharmacokinetics, and Interactions in Humans Absorption is rapid and complete and occurs in the gastrointestinal tract Bioavailability is good and similar in the fed and fasted states 30–40% ... trials and practice experience in Japan, subsequently published in either Japanese or English, and reviewed by Glauser and Pellock (53) In this detailed meta-analysis examining efficacy and safety...
- 92
- 330
- 0
Pediatric Epilepsy Diagnosis and Therapy - part 10 pdf
Ngày tải lên :
12/08/2014, 05:21
... with VNS therapy are generally transient and mild, and are often related to the duration and intensity of stimulation Serious adverse events have not been reported with standard therapy, and no ... United States The VNS therapy system consists of the implantable pulse generator and bipolar VNS therapy lead, a programming wand with software, a tunneling tool, and a hand-held magnet The original ... tamper- 64 • VAGUS NERVE STIMULATION THERAPY IN PEDIATRIC PATIENTS: USE AND EFFECTIVENESS 815 FIGURE 64-5 Intraoperative use of the handheld computer and programming wand to initiate stimulation ing...
- 92
- 367
- 0
Ascites and Renal Dysfunction in Liver Disease Pathogenesis, Diagnosis, and Treatment docx
Ngày tải lên :
14/08/2014, 19:20
... Silvia Ippolito and Kevin P Moore Nitric Oxide and Systemic and Renal Hemodynamic Disturbances in Cirrhosis, 105 Manuel Morales-Ruiz and Wladimiro Jiménez Endothelin and Systemic, Renal, and Hepatic ... Cirrhosis and Ascites, 260 Mónica Guevara, Andrés Cárdenas, Juan Uríz, and Pere Ginès 22 Liver Transplantation for Patients with Cirrhosis and Ascites, 271 Antoni Rimola, Miguel Navasa, Luis Grande, and ... Gülberg and Alexander L Gerbes 10 Carbon Monoxide and the Heme Oxygenase System in Cirrhosis, 125 Richard W Lambrecht, Mercedes Fernández, Ying Shan, and Herbert L Bonkovsky Part Systemic and Splanchnic...
- 454
- 399
- 1
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 1 doc
Ngày tải lên :
09/08/2014, 16:21
... modification and improvement of criteria for the diagnosis of AD is therefore necessary until we understand, and either prevent or cure, this illness IIh Pathogenesis To understand the pathogenesis ... performed Both Lopez and colleagues (1990) and Kukall and colleagues (1990) used four raters to evaluate the NINCDS-ADRDA criteria Using cases with dementia (AD and non-AD) and n o n d e m e n ... patients for evaluation and study, and for the recruitment of patients for drug and other therapeutic trials Variability in the clinical diagnosis of AD is well recognized and major diagnostic issues...
- 10
- 304
- 0
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 2 doc
Ngày tải lên :
09/08/2014, 16:21
... transmembrane domain, and a large N-terminal extracellular domain (Haas, 1996; Neve and Robakis, 1998; Storey and Cappai, 1999; Wilson et al., 1999; Coughlan and Breen, 2000; Gandy and Petanceska, ... on its ability to form fibrils (Haas, 1996; Neve and Robakis, 1998; Storey and Cappai, 1999; Wilson et al., 1999; Coughlan and Breen, 2000; Gandy and Petanceska, 2000) The peptide is derived by ... pathway generating Aft peptide (Haas, 1996; Neve and Robakis, 1998; Storey and Cappai, 1999; Wilson et al., 1999; Coughlan and Breen, 2000; Gandy and Petanceska, 2000) During transport to the cell...
- 10
- 225
- 0
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 3 pptx
Ngày tải lên :
09/08/2014, 16:21
... understanding of the association between A/3 deposition (required for a diagnosis of AD) and the degenerative process The link between soluble A/3 and brain atrophy needs to be clarified, and mechanisms ... from 2.1 to 9.9 and reflect data obtained from prevalence and incidence studies 190 JILLIAN J KRIL AND GLENDA M HALLIDA¥ A DOMINANT INHERITANCE It is estimated that between 5% and 10% of AD cases ... of e2, e3, and e4, and the presence of the e4 allele has been f o u n d to increase the risk o f A D (Katzman, 1994; Strittmatter and Roses, 1995) ApoE is involved in lipid transport and is present...
- 10
- 242
- 0
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 4 pps
Ngày tải lên :
09/08/2014, 16:21
... 259-265 Gahtan, E., and Overmier, J B (1999) Inflammatory pathogenesis in Alzheimer's disease: Biological mechanisms and cognitive sequeli Neurosci Biobehav Rev 23, 615-633 Gandy, S., and Petanceska, ... cortex and their disruption in Alzheimer and Lewy body dementias Proc Natl Acad Sci USA 97, 5039-5043 Burns, A., Luthert, E, Levy, R., Jacoby, R., and Lantos, P (1990) Accuracy of clinical diagnosis ... disease and its risk factors and an increased risk of AD B SUMMARY A hypothesis has been presented that links many of the identified and putative risk factors forAD and suggests a mechanism for...
- 10
- 466
- 0
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 5 doc
Ngày tải lên :
09/08/2014, 16:21
... drug use and Alzheimer-type pathology in aging Neurology 50, 986-990 Maki, E M., and Resnick, S M (2000) Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition ... 12101211 210 JILLIAN J KRIL AND GLENDA M HALLIDAY McGeer, P L., and McGeer, E G (1995) The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative ... 140, 256-261 Paganini-Hill, A., and Henderson, V (1996) Estrogen replacement therapy and risk of Alzheimer's disease Arch Intern Med 156, 2213-2217 Pakkenberg, B., and Gundersen, H J G (1997)...
- 10
- 247
- 0
Investigations on keloid pathogenesis and therapy
Ngày tải lên :
14/09/2015, 13:18
... Radiotherapy: Radiotherapy has been used as monotherapy, and in combination with surgery, for hypertrophic scars and keloids It is effective in reducing the recurrence rate of scars However, monotherapy ... kinds of cells and tissues, and their importance in wound healing and cancer led to their investigation as potential players in keloid pathogenesis The study demonstrated that both SCF and c-KIT were ... in keloids and to understand and assess the role of these modulators towards this fibrotic phenotype This study aims to identify key modulators of cellular dynamics in keloid scars and investigate...
- 168
- 273
- 0
Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
Ngày tải lên :
25/10/2012, 11:35
... Xu B and Song J Prevalence and risk factors of overactive bladder syndrome in Fuzhou Chinese women Neurourol Urodyn 2006; 25:717 Teleman PM, Lidfeldt J, Nerbrand C, Samsioe G, Mattiasson A and ... there was a statistically significant association between OAB and hepatitis (p=0.03, OR=2.2) See Table Table Prevalence of OAB, LUTS and OAB subtypes DISCUSSION The prevalence of OAB in men has ... urinary symptoms (OAB, LUTS and/ or BPH) Furthermore, those with OAB had a worse quality of life score Mean quality of life score for those with OAB was 3.4 of 6, and those without OAB 1.6 Thus,...
- 4
- 520
- 0
Tài liệu Cognitive Impairment in the Elderly – Recognition, Diagnosis and Management docx
Ngày tải lên :
13/02/2014, 18:20
... the Elderly – ecognition, Diagnosis and Management R Revised January 30, 2008 Recommendation Diagnosis When delirium and depression have been treated and/ or ruled out and cognitive impairment ... understand their present condition and prognosis, and have they been able to participate in the development of goals and realistic expectations for treatment? • Is the patient a suitable candidate ... left handed Take a piece of paper, hold it up in front of the person and say: Take this paper in your right/left hand (whichever is non-dominant), fold the paper in half once with both hands and...
- 30
- 501
- 0
Tài liệu Diagnosis and management of head and neck cancer docx
Ngày tải lên :
14/02/2014, 22:20
... acute radiotherapy and chemotherapy toxicity 26 1++ TREATMENT: CHEMOTHERAPY IN COMBINATION WITH SURGERY OR RADIOTHERAPY 8.2 Cetuximab in addition to radical radiotherapy A multicentre randomised ... definitive radiotherapy (with or without chemotherapy) and the neck with adjuvant radiotherapy (with or without chemotherapy) Radiotherapy delivered postoperatively to the primary site and/ or neck ... by radiotherapy or chemoradiotherapy alone.196,198 N2 and N3 disease is better treated by a combination of surgery and chemoradiotherapy (or radiotherapy in those unable to tolerate chemotherapy)...
- 96
- 554
- 0
Tài liệu Burns Regenerative Medicine and Therapy pdf
Ngày tải lên :
17/02/2014, 14:20
... excision and skin grafting therapy , and (2) ‘conservative repairing therapy (burns regenerative 16 Burns Regenerative Medicine and Therapy medicine and therapy) ’ The former is symbolized by the therapy ... Burns Regenerative Medicine and Therapy 31 32 Burns Regenerative Medicine and Therapy Case 2: Burns Regenerative Medicine and Therapy (BRT with MEBT/MEBO) Procedure and Results (fig 8, 9) First ... repair tissues and regenerate organs in vivo and in situ The mapping process of regeneration and duplication of human tissues and organs in vivo and in situ represents a general and typical process...
- 157
- 398
- 0