... Results Quantitative analysis of membrane proteins from paired tumoral and adjacent normal tissue of CRC patients A total of eight tumor tissues and eight matched normal tissues were collected ... and molecular function (Fig 3) To better understand the probable roles of the membrane proteomes in terms of their biological functions, the subcellular localization and molecular functions of ... HLA-A1, SLC25A4 and TAPBP The results of the western blot analysis in the tumoral and normal tissues confirmed the LC-MS ⁄ MS results The expression 3032 levels of CLDN3, HLA-A1 and SLC25A4 were...
Ngày tải lên: 16/02/2014, 15:20
... Pandy MG: Computer modeling and simulation of human movement Annu Rev Biomed Eng 2001, 3:245-273 Shelburne KB, Pandy MG, Anderson FC, Torry MR: Pattern of anterior cruciate ligament force in normal ... The influence of muscles on knee flexion during the swing phase of gait J Biomech 1996, 29:723-733 Anderson FC, Goldberg SR, Pandy MG, Delp SL: Contributions of muscle forces and toe-off kinematics ... differentiate between the roles of gastrocnemius and soleus during the stance phase of normal walking Though these muscles are often grouped together functionally as plantarflexors of the ankle, important...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo khoa học: "Infrared spectroscopy characterization of normal and lung cancer cells originated from epithelium" pdf
... bands at ∼1,460 and ∼1,400 cm could be ascribed to the in-plane bending vibrations of CH3 On the other hand, the vibrational bands at ∼1,235 and ∼1,085 Characterization of normal and lung cancer ... were normalized with respect to that of the amide I band at ∼1,650 cm 1 Table Spectral data and vibrational assignments of normal and lung cancer cells* Normal cells † (NHBE ) Cancer cells (NCI-H358) ... Infrared spectra of lung cancer cells The infrared spectra of lung cancer cells were recorded as shown in Figs 1b and c It is noteworthy that the νs(PO32) and νs(PO2 ), bands at ∼970 and ∼1,085 cm...
Ngày tải lên: 07/08/2014, 23:22
Báo cáo y học: "Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reacti" potx
... weights and ages of the patients were normally distributed and thus compared with the calculation of means and Student t tests The weight of the articular cartilage samples and quantity of RNA ... calculations of means, standard deviations, and fold changes from normal and paired twotailed t tests (body weight and age) performed in a spreadsheet program (Microsoft Excel 2003; Microsoft Corporation, ... Figures and 2, with all data normalised to the mean of the control values (with a fold change of being no change, a fold change of meaning a doubling of expression, and a fold change of 0.5 meaning...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Effect of interleukin-1β on spinal cord nociceptive transmission of normal and monoarthritic rats after disruption of glial function" pot
... reduction) of wind-up scores in the MP group 20 and 40 minutes Figure Effect of IL-1β on C-reflex integrated activity in propentofylline -and saline-treated normal and monoarthritic rats (NS, MS, NP, and ... propentofylline- and saline-treated normal and monoarthritic rats (NS, MS, NP and MP groups) (a) groups) Time course of wind-up scores (% change) 10, 20 and 40 minutes after administration of saline ... standard laboratory conditions and were given food and water ad libitum With the purpose of knowing the monoarthritic and hyperalgesic condition of the rats, we measured the circumference of...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
... EL and HA: carried out the immunofluorescence assays and drafted the manuscript; JLB and MS: conceived the envelope-derived tagged ligands while; JLB, HA, ML and JT: generated, optimized and ... al.: Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport Journal of Biomedical Science 2010 17:91 ... step-size of μm with a specimen magnification of 100× Deconvolution was performed through Huygens professional software (Scientific Volume Imaging, Hilversum, The Netherlands) with 0% background offset...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes" pdf
... pattern of expression, that is high expression of ACAN in NP and AC, high expression of type I collagen in AF compared with NP and AC, and high expression of versican (VCAN) in both NP and AF ... or protein profiles of IVD cells and AC cells Hypoxia inducible factor isoforms (HIF1A and HIF1B), glucose transporter type Page of 20 (GLUT-1), matrix metalloproteinase (MMP-2) and vascular ... (FOXF1), and fibulin (FBLN1)) and the chondrogenic marker genes (aggrecan (ACAN) and type II collagen (COL2A1)), was normalised to the housekeeping gene and normal annulus fibrosus (AF) or NP cells and...
Ngày tải lên: 12/08/2014, 11:23
Basic Electrocardiography Normal and abnormal ECG patterns - Part 1 pdf
... Electrocardiography NORMAL AND ABNORMAL ECG PATTERNS Basic Electrocardiography NORMAL AND ABNORMAL ECG PATTERNS A Bayés de Luna, MD, FESC, FACC Professor of Medicine, Universidad Autonoma Barcelona Director of ... Introduction, Usefulness and limitations of electrocardiography, Electrophysiological principles, The origin of ECG morphology, ECG machines: how to perform and interpret ECG, 19 Normal ECG characteristics, ... usefulness of the clinical aspects is not left aside, since ECG assessment need to be done considering the clinical setting In this book, we explain the origin of normal ECG and the normal and abnormal...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 2 pdf
... projection of P, QRS and T loops on positive and negative hemifields of different leads in frontal and horizontal planes explains the morphology of ECG, and according to the rotation of a loop ... interval and segment and QT interval, calculating the electrical axis of the heart, analysing sequentially the different waves and segments of the ECG (P, QRS, ST, T and U waves) CHAPTER Normal ECG ... Sinus rhythm Ectopic rhythm ER −+ Figure 21 The sinus P wave (anti-clockwise rotation in FP and HP, and ± morphology in III and V1 and −/+ in VL) and ectopic P wave (clockwise rotation and morphology...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 3 pps
... second ICS and positive or +/− in fourth ICS Normal < 0.12 s Normal From < 0.12 to ≥0.12 s Normal Often ≥0.12 s Often tall and peaked and + or ± Often abnormal Often ≥0.12 s Sometimes ≥0.12 s Normal ... and above characteristic for the apical type of hypertrophic cardiomyopathy Below: two examples of aortic valve disease; one (left) with mild septal fibrosis and normal ECG and VCG (presence of ... explain the different ECG patterns The changes produced move the loop rightwards and posteriorly more as a consequence of the delay of activation of RV than of an increase of right ventricle mass...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 4 ppsx
... the upper part of Figure 43, location of the block and activation of the left ventricle in the case of a superoanterior hemiblock and the loop–hemifield correlation in frontal and horizontal planes ... branch, trunk of the left bundle branch, superoanterior division and inferoposterior division of the left bundle (Figures and 17), besides the isolated blocks of just one fascicle, blocks of two fascicles ... > SIII and SI is present This is due to the fact that in SAH the final vector of depolarisation is directed upwards and to the left, and in the case of SI , SII , SIII morphology upwards and to...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 5 pps
... 72), and in non STE-ACS include cases of ST segment depression and flat or negative T wave, and even of normal ECG As a matter of fact, 10–15% of ACS present a normal ECG pattern without pain and ... patterns (ECG pattern of ischaemia, injury and necrosis) The relationship between the degree of ventricular wall involvement, degree and type of ischaemia and electrocardiographic patterns of ischaemia, ... vector of injury or as a consequence of the sum of TAPs of the two parts of the left ventricle subendocardium plus subepicardium According to the theory of vector of injury, in the case of injury...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 6 pps
... deviations of ST segment for location of area at risk; (B) the usefulness of the sum of ST deviations for the quantification of ischaemia; and (C) the ST morphology to detect the grade of ischaemia ... be seen , , Normal ECG, nearly normal or unchanged during ACS C ECG patterns in presence of confounding factors, LVH, LBBB, PM, WPW Electrocardiographic pattern of ischaemia, injury and necrosis ... give us a presumptive diagnosis of a culprit artery, site of the occlusion and area at risk, and quantification and grade of ischaemia [37,38] (See Figures 73 and 74.) Acute coronary syndromes...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 7 pot
... features of ECG in hypertrophic cardiomyopathy are striking signs of LV enlargement and the presence of abnormal ‘q’ wave (see section ‘Left ventricular enlargement’ in Chapter and Table 17) ECG of ... degree AV block of vagal origin and also rSr’ in V1 due to delay of activation of right ventricular and sometimes some degree of right ventricular enlargement (see Case 22) ECG pattern of poor prognosis ... Example of inferior MI (Q in II, III, VF) with involvement of segments and 10 (A and D), and rS morphology in V1 There is no lateral and septal involvement (E) Most probable ECG pattern place of occlusion...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 8 doc
... space) and is recording the tail of the P vector (negative P) and the head of the third vector of ventricular depolarisation (terminal R) The lower location of the lead (B) decreased this image and ... The normal clinical observation of the patient, including the echocardiography and the absence of pulmonary involvement, also the age and the presence of pectus excavatum, together with the normal ... diagnosis? A Left ventricular enlargement B Normal ECG variant; vertical heart with apparent levorotation C Normal ECG variant; horizontal heart D Normal ECG; heart with no rotation 126 Self-assessment...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 9 pptx
... the ECG of a patient with a severe and long-standing aortic valve disease (the ECG is shown at half voltage) The QRS complex morphology in lead V6 is a pure R wave (36 mm) with a pattern of strain ... beginning of ventricular depolarisation is directed anteriorly but to the left, which explains the absence of a q wave in V5 and V6 Thus, this is the case of significant and long-standing left ... through V5 and in VR and VL) and an evident ST-segment depression that is apparent in leads II, III, VF and V6 Give your comments, and your opinion, regarding the characteristics of the occluded...
Ngày tải lên: 13/08/2014, 12:20
Basic Electrocardiography Normal and abnormal ECG patterns - Part 10 potx
... Comment This ECG is clearly pathologic No normal variant can explain the morphology seen in V4–V6 with the absence of R wave in V5 and the appearance of a low-voltage QS or QR pattern in V6 and Q wave ... very abnormal The QRS is narrow and the rsr in V1 is found often in athletes without evident right ventricle (RV) hypertrophy or RBBB, but with some delay of activation of basal part of the RV ... interpreting, 19–20 automatically, 19–20 manually, 20 limitations of, 4–5 morphologies, origin of, nomenclature of intervals and segments and, 14f normal characteristics, 21–31 heart rate, 21, 22f P wave,...
Ngày tải lên: 13/08/2014, 12:20
Báo cáo y học: " Computer simulation analysis of normal and abnormal development of the mammalian diaphragm" doc
... uncertainties notwithstanding, computer simulations can allow us to understand morphogenesis of the normal mammalian diaphragm and the events that underlie the abnormal development of CDH and other anomalies ... the standards of the Institutional Animal Care and Use Committee of Columbia University Five micron transverse serial sections were cut and stained with hematoxylin and eosin Image analysis and ... defects Of mice and men The classic description of the location of the defect in human CDH is postero-lateral (Fig 1) [1,4] There is large variation in the size and extent of the defect and large...
Ngày tải lên: 13/08/2014, 23:20
Epigenetic regulation of normal and malignant hematopoiesis
... mSin3A and HDAC1 in MEL and human T-ALL cells was linked to transcriptional repression and inhibition of erythroid differentiation (Huang and Brandt, 2000) The association between TAL1/SCL and mSin3A/ ... and more than 60 different fusion partners occur in a significant proportion of patients with AML and ALL (Daser and Rabbitts, 2005) Furthermore, an internal tandem duplication of MLL is one of ... PRC2, and 4, comprised of enhancer of zeste protein-2 (EZH2), which specifically methylates H3K27 and H1K26 in a complex-dependent manner, SUZ12, histone-binding proteins RbAp46 and 48 and one of...
Ngày tải lên: 05/09/2015, 11:25