... constants k1, k4 and k8 correspond to heme reduction; k2 and k5 correspond to oxygen binding; and k3 and k6 correspond to catalytic steps k7 and k9 correspond to the release of NO from ferric and ferrous ... k1, k4, k¢4 and k8 correspond to heme reduction; k2 and k5 correspond to oxygen binding; and k3 and k6 correspond to catalytic steps k7 and k9 correspond to release of NO from ferric and ferrous ... endotheliumderived relaxing factor and the chemical reactivity of nitric oxide J Exp Med 169, 1011–1020 Abu-Soud HM & Stuehr DJ (1993) Electron transfer in the nitric- oxide synthases Nitric oxide synthases reveal...
Ngày tải lên: 07/03/2014, 00:20
... implicated in the formation of nitric oxide by vascular endothelial cells Biochem Biophys Res Commun 158, 348–352 Muruganandam, A & Mutus, B (1994) Isolation of nitric oxide synthase from human platelets ... L-arginine transport and nitric oxide production by gabexate mesylate Biochem Pharmacol 64, 277–283 Closs, E.I., Scheld, J.S., Sharafi, M & Forstermann, U (2000) Substrate supply for nitric- oxide synthase ... Atherosclerosis 117, 273–284 11 Wang, B.Y., Candipan, R.C., Arjomandi, M., Hsiun, P.T., Tsao, P.S & Cooke, J.P (1996) Arginine restores nitric oxide activity and inhibits monocyte accumulation after...
Ngày tải lên: 08/03/2014, 02:20
carbon dioxide and environmental stress
... 187 172 Role of Carbon Dioxide in Modifying the Plant Response to Ozone Andrea Polle and Eva J Pell I II III IV Introduction 193 Evidence of Interactions between Ozone and Carbon Dioxide Mechanisms ... Responses Jelte Rozema, Alan Teramura, and Martyn Caldwell I Introduction 169 II Evolution of Atmospheric Oxygen and Carbon Dioxide, Terrestrial Plant Life, and Solar Ultraviolet-B Radiation 171 ... Nitrogen Mineralization and Immobilization and Increased Carbon Input to Soil 268 V Increased Carbon Flux to Soil and Nitrogen Inputs and Losses 274 VI Altered Nitrogen Cycling and Soil Water Content...
Ngày tải lên: 01/04/2014, 11:43
Báo cáo y học: "Ex vivo effects of flavonoids extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behcet''''s disease" pptx
... Koppenol WH: Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly Amer J Physiol 1996, 271: C1424C1437 12 Yu L, Gengro PE., Niedrberger M, Burk TJ , Schrier, RW: Nitric oxide: A ... Ko Ch, Yang LL, Chen YC: In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production Eur J Pharmacol ... and up-regulation of Th1 and Th2 cytokines, respectively Moreover, flavonoùds may prevent nitric oxide induced damages Keywords: Adamantiades-Behỗets disease; Immunomodulation; IL-4; IL-12; nitric...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc
... hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies Curr Mol Med 2004, 4:753-62 Moncada S, Higgs EA: Nitric oxide and the vascular endothelium Handb Exp Pharmacol 2006, ... Xie QW, Nathan C: Nitric oxide and macrophage function Ann Rev Immuno 1997, 15:323-50 Kleinert H, Pautz A, Linker K, Schwarz PM: Regulation of the expression of inducible nitric oxide synthase Eur ... pro-inflammatory cytokines and inhibit iNOS expression and NO release in LPS-stimulated RAW264.7 macrophages by targeting the NFB activation pathway Materials And Methods Cell Culture and Sample Treatment...
Ngày tải lên: 11/08/2014, 08:22
báo cáo khoa học: " Auxin and nitric oxide control indeterminate nodule formation" ppt
... Medicago sativa and Phaseolus vulgaris seedlings were grown in small pots on sand and perlite mixture (1:1) in a greenhouse at day and night temperatures of 24°C and 18°C, respectively, and 10 h light/14 ... M, Lamattina L: Nitric oxide plays a central role in determining lateral root development in tomato Planta 2004, 218:900-905 Pagnussat GC, Lanteri ML, Lamattina L: Nitric oxide and cyclic GMP ... strain (Fig 3B and Fig 4A) The weight and size of the nodules were on average identical regardless of whether plants were nodulated by the IAA or control strain (Fig 3A and Fig 3B and data not...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: "Atrial natriuretic peptide infusion and nitric oxide inhalation in patients with acute respiratory distress syndrome" ppt
... variant of hantavirus Scand J Infect Dis 1995, 27:453–456 Young JD, Dyar OJ: Delivery and monitoring of inhaled nitric oxide Intensive Care Med 1996, 22:77–86 Adnot S, Andrivet P, Chabrier PE, ... 245–260 25 Gerlach H, Rossaint R, Pappert D, Falke KJ: Time-course and dose–response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with acute respiratory ... detection, and the mean time difference between the occurrence of the first particle and all the following particles The product of CO and MTT is the volume between the site of injection and the...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Equipment review: New techniques for cardiac output measurement – oesophageal Doppler, Fick principle using carbon dioxide, and pulse contour analysis" pot
... of the carbon dioxide dissociation curve This curve represents the relation between carbon dioxide volumes (used to calculate carbon dioxide content) and partial pressure of carbon dioxide This ... whereas the arterial carbon dioxide content (CaCO2) is estimated from end-tidal carbon dioxide (etCO2), with adjustments for the slope of the carbon dioxide dissociation curve and the degree of ... partial rebreathing reduces carbon dioxide elimination and increases etCO2 Measurements under normal and rebreathing conditions allow one to omit the venous carbon dioxide content (CvCO2) measurement...
Ngày tải lên: 12/08/2014, 18:21
Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
... pro- and anti-inflammatory cytokines, nitric oxide, reactive oxygen species (ROS), glutamate, and growth factors (Harry and Kraft, 2008) Microglia also express the glutamate transporter, GLT-1 and, ... cells and SphK1 alters the expression and production of proinflammatory cytokines and nitric oxide in microglia treated with lipopolysaccharide (LPS) LPS treatment increased the SphK1 mRNA and ... tissue, and remove degenerating and dysfunctional cells (Harry and Kraft, 2008) The activated microglia in response to CNS inflammation secrete proinflammatory cytokines such as TNF-α and IL-1β and...
Ngày tải lên: 16/10/2015, 15:38
Báo cáo khoa học: Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations pdf
... full and intermediate oxygen saturations, and Hb will never become fully deoxygenated It is therefore important to understand how the reaction of nitrite with Hb proceeds at intermediate oxygen ... blood cell pH, the Bohr effect, and other oxygenation-linked phenomena in blood O2 and CO2 transport Acta Physiol Scand 182, 215227 22 Jensen FB (2007) Nitric oxide formation from nitrite in ... concentrations of oxygenated hemoglobin, methemoglobin, nitrosylhemoglobin and deoxygenated hemoglobin during the reaction of nitrite with carp hemoglobin at different oxygen saturations Initial oxygen...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo y học: "Fluctuations of inspired concentrations of nitric oxide and nitrogen dioxide during mechanical ventilation" ppt
... 0.1 NO (ppm) Individual nitrix dioxide (NO2) measurements in parts per million (ppm, y-axis) for the different nitric oxide (NO) concentrations adjusted (xaxis, NO) and the different FiO2 values ... Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn Lancet 1992, 340:819–820 Roberts JD, Polander DM, Lang P, Zapol WM: Inhaled nitric oxide in persistent pulmonary ... respiratory distress syndrome N Engl J Med 1993, 328:399–405 Stavert DM, Lehnert BE: Nitric oxide and nitrogen dioxide as inducers of acute pulmonary injury when inhaled at relatively high concentrations...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
... S, Mori M Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC 12 cells and high output production of nitric oxide Mol Brain Res 2000; 83: 1-8 ... amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells Mol Brain Res 2001; 90: 165-173 20 Swamy M, Sirajudeen KNS, Chandran G Nitric oxide [NO] citrulline-NO ... between nitric oxide and dementia of Alzheimer’s type Brain Res Rev 2001; 35: 73-96 42 Serrano J, Encinas JM, Salas E, et al Hypobaric hypoxia modifies constitutive nitric oxide synthase activity and...
Ngày tải lên: 26/10/2012, 09:07
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf
... Alderton WK, Cooper CE & Knowles RG (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 Stuehr DJ (1999) Mammalian nitric oxide synthases Biochim Biophys Acta 1411, ... autoinhibitory control element and calmodulin conspire to provide physiological modulation of endothelial and neuronal nitric oxide synthase activity Acta Physiol Scand 168, 53–63 Montgomery HJ, ... of constitutive nitric- oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin J Biol Chem 275, 29225–29232 Tiso M, Tejero J, Panda K, Aulak...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx
... concentrations of LPS and IFN NO production is reported to be stimulated by LPS and IFN through independent signal pathways; LPS and IFN stimulate cells by activating NF-jB and the interferon regulatory ... the effects of inhibitors of PKA and PKC on TS-enhanced NO production As shown in Fig 5A, the PKA inhibitors KT-5720 and H8 and the PKC inhibitors Ro31-2880 and GF109203X did not affect apparently ... Effects of PKA inhibitors (KT-5720 and H8) and PKC inhibitors (Ro31-8220 and GF109203X) on the enhancement by TS of LPS/IFNinduced NO production in VSMC (A), and Western blot analysis of PKCa...
Ngày tải lên: 22/02/2014, 04:20
Cardiac and Hemodynamic Changes during Carbon Dioxide Pneumoperitoneum for Laparoscopic Gynecologic Surgery in Rajavithi Hospital ppt
... the factors for patient’s recruitment Carbon dioxide pneumoperitoneum has been shown to produce respiratory and hemodynamic changes due to both CO2 absorption and the effects of increased intraperitoneal ... Impact of carbon dioxide and helium insufflation on cardiorespiratory function during prolonged pneumoperitoneum in an experimental rat model Surg Endosc 2002; 16: 1073-8 Nguyen NT, Anderson JT, ... Wright DM, Serpell MG, Baxter JN, O’Dwyer PJ Effect of extraperitoneal carbon dioxide insufflation on intraoperative blood gas and hemodynamic changes Surg Endosc 1995; 9: 1169-72 Hazebroek EJ, Haitsma...
Ngày tải lên: 05/03/2014, 15:20
Báo cáo khoa học: Binding and activation of nitric oxide synthase isozymes by calmodulin EF hand pairs potx
... FAD, and FMN, and the oxygenase domain contains binding sites for heme, tetrahydrobiopterin (H4B), and the substrates l-arginine and molecular oxygen [7] A CaM-binding domain separates the oxygenase ... RG (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 ´ Roman LJ, Martasek P & Masters BS (2002) Intrinsic and extrinsic modulation of nitric oxide synthase ... sites of calmodulin and electron transfer by neuronal nitric oxide synthase Biochemistry 36, 12337–12345 11 Ghosh DK & Salerno JC (2003) Nitric oxide synthases: domain structure and alignment in...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx
... 3.8- and 3.6-fold lower than those for their nonfluorinated analogues BuGua and BuNOHG, respectively, and the koff app values for TFBGua and TFBNOHG are 1.6 and times lower than those for BuGua and ... 7- and 25-fold lower than that for l-Arg, and those for the non-a-amino acid N-hydroxyguanidines BuNOHG and TFBNOHG were 3- and 12-fold lower than that for NOHA The koff app values for BuGua and ... be 10 and times higher than that for l-Arg, and those for BuNOHG and TFBNOHG were 20 and times higher than that for NOHA Interestingly, konapp values for the fluorinated compounds TFBGua and TFBNOHG...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production Inflamm Res 49, 20–26 Lu SC, Chang SF, ... of nitric oxide (NO) to combat invading pathogens [6] and G-CSF stimulates the production, growth and function of neutrophils [7,8] Both iNOS and G-CSF genes are expressed in macrophages and ... of Oct-2 and its potential target genes, iNOS and G-CSF, in RAW264.7 cells and in THP-1 cells The results demonstrated that rapamycin reduced Oct-2 protein levels and attenuated iNOS and G-CSF...
Ngày tải lên: 22/03/2014, 17:20
A Comparative Analysis of Carbon Dioxide Emissions in Coated Paper Production Key Differences between China and the U.S. pot
... 31 Major sources of carbon dioxide emissions from BHKP production 31 Major sources of carbon dioxide emissions from BSKP production 31 Summing up: Carbon Dioxide Emissions in China’s ... overall 31 Figure 4.3 Carbon Dioxide Emissions per Metric ton of BSKP by Energy Type Summing up: Carbon Dioxide Emissions in China’s Coated Paper Facilities The carbon dioxide emissions from energy ... count carbon dioxide emissions from combustion of the biomass itself Method This analysis compares the differences in energy use and related carbon dioxide emissions between the Chinese and U.S...
Ngày tải lên: 24/03/2014, 05:20