Ngày tải lên: 14/08/2014, 08:20
Ngày tải lên: 14/08/2014, 16:21
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 27) ppt
... Springer-Verlag Berlin Heidelberg 2005 II.3.1 Phenothiazines by Akira Ishii and Yoshinao Katsumata Introduction Phenothiazine drugs, including chlorpromazine and levomepromazine, have been being ... Poisoning due to psychotropic agents. Adverse Drug React Acute Poisoning Rev 4:83–126 3) Geraut A, Kintz P, Traqui A et al. (1994) Toxicological findings in a fatality involving chlorpromazine. ... (1 min) →15 °C/min e → 290 °C (10 min); injection temperature: 270 °C; interface temperature; 270 °C; carrier gas: He; its ow rate: about 1.5 mL/min; injection: splitless mode for 1 min followed...
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28) pptx
... Igarashi Introduction Butyrophenone drugs including haloperidol are being widely used in the eld of psychiatry. e acute butyrophenone poisoning incidents sometimes take place; in such cases, ... procedure i–v described in the GC/MS analysis section is followed for a urine or blood specimen to obtain a residue containing butyrophenones. e residue is dissolved in 0.1 mL of the mobile ... temperature: 100 °C (1 min) → 30 °C/min → 270 °C (30 s) → 5 °C/min → 290 °C (5 min); injection temperature: 260 °C; separator tempera- ture: 280 °C; carrier gas: He; its ow rate: 1.5 mL/min; MS ionization...
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 29) ppt
... also in- cluded in this chapter. GC/MS analysis Reagents and their preparation ã Amitriptyline, carbamazepine, clomipramine, desipramine, imipramine, maprotiline, mi- anserin, nortriptyline ... carbamazepine obtained by GC/MS. A: amitriptyline, B: mianserin, C: nortriptyline, D: imipramine, E: desipramine, F: promethazine (IS), G: setiptiline, H: carbamazepine, I: maprotiline, J: clomipramine, ... solvent can be chosen according to the kind of a target drug. e) Imipramine and amitriptyline are metabolized into desipramine and nortriptyline, respec- tively, in a human body. Both metabolites...
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 31) ppt
... hypnotics being sold as over-the-counter drugs. Because of the easiness of getting it, bromisovalum is one of the most important drugs in poisoning in Japan. e analysis of bromisovalum is being made ... 5.1) contained in Wutt appears at 5.07 min under the present HPLC conditions and thus can be an indicator of ingestion of Wutt. In some analgesic-antipyretics, bromisovalum is also contained together ... containing about a half volume of water were found. By dental nd- ings, the remains were found to be a 46-year-old male who had been missing for 7 months. Using the femoral bone marrow, the analysis...
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 32) ppt
... of Vegetamin (a combined drug containing, phenobarbital, promethazine and 3.63.6 â Springer-Verlag Berlin Heidelberg 2005 II.3.6 Barbiturates by Masaru Terada and Ritsuko Watanabe Introduction Barbiturates ... for analysis of barbiturates by GC and HPLC are presented. Incidence of fatal barbiturate poisoning cases. Since fatal cases due to Vegetaminđ tablets containing phenobarbital are many, its incidence ... female was found dead in her room; she had committed suicide by injecting an alate needle into a vein of the right dorsum pedis for drop infusion of thiopen- tal (its amount infused not clear)....
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 37) pptx
... and antihistaminic drugs were administered intravenously. All drugs for oral intake except phenytoin were discontinued on day 3 a er admission. e administra- tion of phenytoin was also stopped ... beta-blocking drugs. Farmaco 55:136–145 Poisoning cases 4.54.5 â Springer-Verlag Berlin Heidelberg 2005 II.4.5 Antiepileptics by Einosuke Tanaka Introduction As antiepileptics, phenytoin, mephenytoin, ... 2.95 min); PB: phenobarbital (5 mg/mL, 3.33 min); CBZ-E: carbamazepine-epoxide (1 mg/mL, 4.48 min); IS: 9-hydroxymethyl-10-carbamyl acridan (IS, 5.92 min); PT: phenytoin (2.5 mg/mL, 9.45 min); CBZ:...
Ngày tải lên: 15/12/2013, 12:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 38) pptx
... relaxants in urine, serum and tissue homogenate can be extracted, but especially suxamethonium (succinylcholine) is rapidly hydrolyzed in blood by the action of cholinesterase; since it is ... dissolved in methanol just before use a . ã Synthesis of succinylmonocholine iodide [2]: 2.3 g choline iodide and 5 g succinic anhy- dride are mixed and fused for reaction by heating the mixture ... for 1–2 h in an oil bath. A er cooling to room temperature, the excessive (not reacted) succinic anhydride is washed with 100 mL acetone, succinyl monocholine iodide is crystallized in the mixture...
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 39) ppt
... e ective in suppressing muscle quivering and in suppressing overreaction of the thyroid gland upon being too nervous, they are used as doping drugs in competitive sports such as shooting and ... the brain, the drugs attenuate migraine by suppressing the dilation of blood vessels; in the eye, they decrease intraocular pressure by suppressing the production of aqueous humor. Since the ... chromatograms for -blockers extracted from urine of subjects, who had ingested each of them. The results were obtained after single oral intake of each drug. In the analysis of atenolol, double peaks...
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 43) pptx
... report describing the di culty for detecting hypochlorite from blood of a victim, who committed suicide by ingest- ing a bleaching agent [3]. Notes a) Hypochlorite is very unstable in acidic aqueous ... alkaline or weakly acidic conditions to produce chloride ion together with oxygen in the activated state, resulting in its bleaching action. References 1) Yokogawa Analytical Systems (1999) Instruction ... chlorate ions are contained. During preparation of the solutions and also during analysis, there is a possibility of decomposition of the hypochlorite ion. As shown in > Figure 1.1, the...
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 46) pptx
... Springer-Verlag Berlin Heidelberg 2005 II.5.4 Permethrin by Naoto Matsumoto Introduction Pyrethroids are the general term for insecticide pyrethrins and their analogs ( cinerins and jasmolins) ... ey are not only being used for household insecti- cides, but also being used in agriculture worldwide. ey count about 1/3 of the total insecti- cides, and are even increasing at the present ... present time. Products containing pyrethroid insecticides are numerous; their toxicities for humans are generally low. However, since phenotrin, permethrin and empenthrin are ubiquitous as powders,...
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 47) ppt
... spectrophotometric analysis of boric acid in a urine specimen, the value obtained may be slightly greater than the true value. is is probably due to interference by a certain urinary element, ... (in Japanese) 2) Fukui S (1983) A method for determination of boric acid in foods using chelating extraction with 2-ethyl-1,3- hexanediol and protonated curcumin. Eisei Kagaku 29:323–328 (in ... acid poisoning symptoms, nausea, vomiting, diarrhea and abdominal pain is most common as observed in the above case; headache, scarlet fever-like exanthemas and desquamation of the skin are sometimes...
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 2) pptx
... are being extended to ultra-sensitive analysis of toxins in hair, nails, saliva and sweat; these specimens are proving to be useful for toxin analysis, because many toxins are excreted into ... However, we should keep it in mind that the drug use with- in 3 days cannot be detected by hair analysis. ⊡ Table 2.1 Segmental analysis of methamphetamine in hair and nails, obtained from a habitual ... specimens for analysis of drugs and poisons for living subjects. A blood concentration of a toxin can be an indicator for estimation of intoxication degree. Urine sometimes contains large amounts...
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 6) ppt
... matrices in which poisons were mixed, viz, drink in a glass bottle, drink in a can, drink in a paper package, drink in a plastic bottle, drink in an un- known container, tea in a pot, tea in a water ... Yoshioka Introduction In addition to the well known Tokyo Sarin Incident in 1995, the arsenic-adulteration incident in Wakayama and the cyanide-adulteration incident in Nagano both in 1998 seem to ... and melting point, are used as keywords for narrowing down toxins. Database according to poisoning symptoms( assisting system for diagnosis of a causative toxin) of subjects of studies being conducted...
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 7) pptx
... treatments may be included. When a poisoning incident takes place with a chemical which is included in the DB, it may give useful informations on treatments and analysis in the poisoning. iv. DB ... resulting in no contribution to clinical treatments; when neither presentation at a meeting nor publication in a journal is realized a er laborious analysis, the principle of being a joint study ... Poison Information Network as “poison-net”, comprehensively. It includes “poisoning mailing list”, analysis mailing list”, supply of informa- tions of poisoning on Web, requests for analysis...
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 48) pptx
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 50) ppt
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 53) pptx
Ngày tải lên: 22/01/2014, 00:20