... remaining SNPs could be explained by LD Our findings indicate that serum concentrations of YKL-40 are under the influence of genetic variability in the CHI3L1 gene in both patients with RA and ... YKL-40 increased with increasing age in both healthy controls and patients with RA making age a possible confounding variable The cause of this remains unknown, but the phenomena has been explained ... YKL-40 in both patients with RA and healthy controls Our findings indicate that the g.-131(C > G) polymorphism is the main contributor to the inter-individual variation of serum YKL-40 in Caucasian...
Ngày tải lên: 12/08/2014, 17:22
... who show cerebral atrophy and lacunar infarction in the brain [1] The risk of aspiration pneumonia in post-stroke patients is known to intimately correlate with the inhibition of the cough reflex ... accumulating evidence indicating that human cough is under voluntary control and that higher centers such as the cerebral cortex or subcortical regions have an important role in both initiating and inhibiting ... inhibiting reflexive cough [4,5] Although the cough reflex is certainly subjected to influence originating from cortical or subcortical brain regions [6], understanding of the nature and function...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: "Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes" ppt
... to patients with DM rashes (two patients with DM, and one patients with CAM associated with a DM rash), whereas anti-Mi-2-LIA (three patients) were associated with OM None of the patients with ... anti-fibrillarin by ALBIA using purified recombinant fibrillarin protein (Mikrogen GmbH, Neuried, Germany) and test serum diluted to 1:1,000 [36] Control negative and standard positive sera were included in ... longitudinal clinical and serologic findings Arthritis Rheum 1999, 42:899-909 Okano Y, Steen VD, Medsger TA Jr: Autoantibody to U3 nucleolar ribonucleoprotein (fibrillarin) in patients with systemic...
Ngày tải lên: 09/08/2014, 10:20
báo cáo khoa học: "Treatment outcome of thalidomide based regimens in newly diagnosed and relapsed/ refractory non-transplant multiple myeloma patients: a single center experience from Thailand" pot
... MM and prolonged thalidomide use had the survival benefit and had minimal serious toxicity in non-transplant MM patients To date, MM remains incurable Novel agents continue to be developed and ... Vincent R, Grzegorz SN, Morie AG, Angela D, Martha QL, Suzanne H, Rafael F, John AL, Robert AK, Philip RG, Thomas EW: Combination therapy with thalidomide and dexamethasone in patients with newly ... thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial Lancet 2006, 367:825-35 Facon T, Mary JY, Hulin C, Benboubker L,...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo y học: " Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB" doc
... NCT01222338 Randomization, clinical endpoints and exclusion/inclusion criteria Any patient who presented with pulmonary TB was enrolled into this study and randomly allocated into two arms according to ... of V5 revealing negative smear conversion in 96.3% of treated subjects [8] Our study was, thus, aimed to verify these findings in an independent clinical setting at our TB hospital in Kharkov ... associated with inflammation were reduced in V5 -treated patients Placebo Figure The proportion of ATT -treated patients in V5 and placebo arms who have benefited from the therapy according to the...
Ngày tải lên: 11/08/2014, 08:21
The assessment of public knowledge on diabetes mellitus and patient reported outcomes measurement among patients with type 2 diabetes in thailand
... Sharon and Jin Jing, for providing me guidance and help I also cherish all my colleagues in S7 02-09, Yingjiao, Mandy, Hua Pey, Regine and Wei Ting, and my unit mates, Sureerat, Nichanan and Poonna, ... department for their kind assistance in administrative issues The journey of my postgraduate study in Singapore would be tougher and boring without having lovely and helpful seniors and friends around ... of health status, QoL and treatment satisfaction among patients with DM in Thailand……………………………………154 8.1.3 Polypharmacy in patients with T2DM in Thailand………………158 8.2 Main limitations……………………………………………………………159...
Ngày tải lên: 11/09/2015, 09:56
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... gabapentin in patients with HCV [55] These findings suggest that valproate can be used for some patients with HCV without adversely affecting ALT levels Obtaining pretreatment baseline ALT levels in ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks ... weight gain and cholesterol and triglyceride elevation in patients with schizophrenia This association is most commonly observed in patients prescribed clozapine and olanzapine, reaching statistical,...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "he Association Among Lipoprotein-associated Phospholipase A2 Levels, Total Antioxidant Capacity and Arousal in Male Patients with OSA"
... arousal index was associated with increased LP-PLA2 level The elevated levels of circulating LP-PLA2 may explain prone to sudden death due stroke and AMI in patients with OSA and increased arousal index ... a minimum of 10 sec, was considered as hypopnea Individuals with an apnea hypopnea index (AHI) >5 were diagnosed as OSAS and included in the study Determining of Arousals An arousal was defined ... triglyceride levels were increased in patients above median arousal and TAC was reduced in these subjects Other demographic and laboratory findings were comparable in two groups According to the arousal...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation"
... including erythema infectiosum in children, polyarthropathy syndrome in adults, transient aplastic crisis inpatients with chronic anemia, persistent infections manifesting as chronic anemia in ... identified in the NS1 gene (Fig 2) In isolates belonging to group 2, the amino acid at position 181 and 201 showed methionine and aspartic acid, respectively Interestingly, aspartic acid substitution in ... major viral proteins: VP1 and NP2, the viral capsid proteins, and NS1, a nonstructural protein Both VP1 and VP2 are derived from overlapping reading frames and share substantial amino acid sequences...
Ngày tải lên: 26/10/2012, 10:03
Diagnostic and Therapeutic Problems of Pulmonary Tuberculosis in Elderly Patients doc
... positive sputum AFB smear was obtained in 57.1% of elderly and in 57.5 % of young TB patients, and a positive AFB culture was obtained in 70.6% of the elderly and in 74.4% of the young, neither ... significantly higher in the elderly (p
Ngày tải lên: 15/03/2014, 03:20
Fertility Sparing Treatments in Young Patients with Gynecological Cancers: Iranian Experience and Literature Review pptx
... sparing in young women with ovarian tumors Clin Exp Obstet Gynecol, 37, 290-4 Gotlieb WH, Beiner MR, Shalmon B, et al (2003) Outcome of fertility sparing treatment with progestin in young patients ... IA1 with lymphovascular invasion (conization indicated) or IA2 and IB1 without lymphovascular invasion, endocervix upper intact, lymph nodes involvement ruled out by paraclinic (Dargent et al., ... Some believed it’s better to perform radical abdominal hysterectomy in patients with tumor size>4cm and radical abdominal trachelectomy in one with tumor size 2-4 cm who wish to preserve 1888...
Ngày tải lên: 22/03/2014, 11:20
ELDERLY SERVICES IN HEALTH CENTERS: A Guide to Address Unique Challenges of Caring for Elderly People with Disabilities, Frailty, and Other Special Needs pot
... living in nursing homes have urinary and/ or fecal incontinence Studies have found that incontinence is an important factor in the decision to institutionalize elderly patients Yet incontinence is ... privately with patients whenever possible ☐☐ Train and support caregivers involved in handling incontinence to preserve the dignity of the elderly individual ☐☐ Help the patient feel comfortable talking ... Difficulty with activities of daily living Role of the Health Center: Training medical providers to ask patients about incontinence at routine appointments, particularly elderly patients with associated...
Ngày tải lên: 22/03/2014, 13:20
Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx
... Figure Serum sFlt-1 and VEGF-A levels in FN Serum sFlt-1 and VEGF-A levels in patients with FN Box plots representing serial concentrations of sFlt-1 and VEGF-A in patients with FN with non-complicated ... Figure sFlt-1 and VEGF-A levels in patients with FN Combined analysis sFlt-1 and VEGF-A levels in patients with FN Actual sFlt-1 and VEGF-A serum levels obtained at fever onset and after 48 hours ... observed between patients with and without septic shock, with increased sFlt-1 concentrations in patients with septic shock (116.0 pg/ml, range 42.7-208.4 pg/ml) compared to patients with non-complicated...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Soluble HLA measurement in saliva and cerebrospinal fluid in Caucasian patients with multiple sclerosis: a preliminary study" pdf
... concentrations in the CSF and saliva of MS patients were further analyzed by subgrouping them into those with enhancing lesions vs those without enhancing lesions on brain MRI, with the understanding that ... levels, in MS has been reported [14] Fainardi et al [15] reported a decrease in sHLA-I concentrations during exacerbations in MS, but an increase in CSF sHLA-I was observed in patients with lesional ... sHLA-I, and an increase in CSF sHLA-I, but not CSF sHLA-II concentrations, in patients with MS [12,13] However, an elevation of CSF sHLA II and I as well as an increase in serum sHLAI, but not in...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pdf
... Figure Serum sFlt-1 and VEGF-A levels in FN Serum sFlt-1 and VEGF-A levels in patients with FN Box plots representing serial concentrations of sFlt-1 and VEGF-A in patients with FN with non-complicated ... Figure sFlt-1 and VEGF-A levels in patients with FN Combined analysis sFlt-1 and VEGF-A levels in patients with FN Actual sFlt-1 and VEGF-A serum levels obtained at fever onset and after 48 hours ... observed between patients with and without septic shock, with increased sFlt-1 concentrations in patients with septic shock (116.0 pg/ml, range 42.7-208.4 pg/ml) compared to patients with non-complicated...
Ngày tải lên: 20/06/2014, 03:20
báo cáo hóa học:" Health-related quality of life in children with newly diagnosed cancer: a one year follow-up study" pptx
... Descriptive information about the sample is contained in Table Sex of patients was not equally distributed, with more boys taking part in the study This is consistent with findings of several international ... between weeks and one year after diagnosis with regard to physical symptoms, motor functioning, autonomy, and positive emotional functioning Interestingly, cognitive and social functioning and the ... rates are now approaching 70% for children with brain tumors and are exceeding 80% for patients with acute lymphoblastic leukemia [1] However, the same treatments leading to increased survival rates...
Ngày tải lên: 20/06/2014, 15:20
Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both pdf
... England Journal of Medicine CORRECTION Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both Sudden Death in Patients with Myocardial Infarction ... LXRα is expressed predominantly in tissues involved in lipid homeostasis in the liver, intestine, adipose tissue, and macrophages LXRα and LXRβ are equally effective in promoting reverse cholesterol ... unlikely to have had training in medical terminology and confidentiality; their priorities sometimes conflict with those of patients; and their presence may inhibit discussions regarding sensitive issues...
Ngày tải lên: 27/06/2014, 00:20
Báo cáo y học: "Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis and Ascite" docx
... Conclusions In conclusion, in patients suffering from severe liver cirrhosis and ascites, portopulmonary shunt, intrapulmonary shunt and VA/Q inequality may induce a decrease in PaO2 and SaO2 in association ... history, clinical examination, laboratory findings, and liver biopsy, which all patients underwent From a clinical point of view the patients conditions varied from moderate to severe according to ... manifested by dyspnea, platypnea and orthopnea and nowadays is more widely diagnosed occurring in chronic liver disease of all types and mainly in severe suffering patients [4, 9, 10, 11] Liver...
Ngày tải lên: 08/08/2014, 18:20
Báo cáo khoa học: "Prediction and prevention of suicide in patients with unipolar depression and anxiety" ppsx
... antidepressants in the background of declining suicide rates, the US Food and Drug Administration recently issued a warning concerning the use of antidepressants in children and adolescents, and possibly in ... (most of whom were treated with antidepressants) among patients having suicidal ideation at baseline, the decline in suicidal ideation was predicted by preceding declines in the levels of both ... underlying factors [1,2,4,5] Therefore, understanding, prediction and prevention of suicidal behaviour is today one of the most challenging tasks in society in general and in psychiatry in particular...
Ngày tải lên: 08/08/2014, 23:20
Báo cáo y học: "Increased plasma homocysteine levels in patients with multiple sclerosis and depression" ppsx
... homocysteine (Hcy) and vitamin B12 in multiple sclerosis (MS) patients and controls Box and1 Box and whisker plot of plasma homocysteine (Hcy) and vitamin B12 in multiple sclerosis (MS) patients and ... homocysteine levels in patients with MS and depression Accordingly, the present study was designed in order to assess Hcy plasma levels in MS patients and investigate whether an association with ... metabolism in MS and investigated whether Hcy levels are related to depression in this disease It is concluded that Hcy is increased in patients with RR-MS without concomitant signs of vitamin B12 and...
Ngày tải lên: 08/08/2014, 23:21