... price in their career opportunities if they take a stand for a vision of balance between work and family. Very often, the person who takes such a stand will command the respect of their peers—many ... family. The disciplines ofthe learning organization will, I believe, end the taboo that has surrounded the topic of balancing work and family, and has kept it off the corporate agenda. The learning ... resource. The success of one means that it tends to get more ofthe resource, which then reduces the success ofthe others. The resource could be limited dollars to invest in competing divisions of...
... schiltrons of pikemen, underRandolph, Edward Bruce, and Sir James Douglas, and Bruce himself commanded the reserve, which wascomposed of Highlanders from Argyll andthe Islands andofthe men of Carrick.[49] ... Scotland to England, ofthe long resistance ofthe Celts of Scotland to the English of Scotland".[4] Above all, the conception has been firmly planted in the imagination by the poet of the ... Bruce of Annandale, who had been promised the succession by Alexander II, and had been disappointed ofthe fulfilment of his hopes by the birth ofthe lateking in 1241. The deaths of two of the...
... slow release ofthe cleavage products from the protein. The amplitudes ofthe initial burst (2.78 and 2.83 nM) gave a ratio of DNA/protein of 0.94 : 1. As will bediscussed further, these data ... hypotheses will needto be performed to determine the binding characteristics of the nucleic acid substrates, both alone and in the presence of one another.Although the structural details of ... about 45 min. The substitution of either Na+for K+or acetate for Cl–ions, as well as the inclusion of 0.1 mgÆmL)1BSA did notincrease the stability ofthe protein and slowed the reactionrate...
... Metz, andof Alsace with Strasburg and their 1,500,000 of Germanspeaking Teutons to the French Empire.Chapter I 7Chapter I THE CAUSES OFTHEWARANDTHE FOUNDATION OF PEACESince the war, foreshadowed ... toIreland instead of to Egypt the Empire of England was at an end."With these two utterances ofthe French writer andofthe French ruler we begin and end the reference of Ireland to European ... enough ofthe Irishman through all his official connection to see the two sides of a question and appreciate the point of view ofthe other man.What Lever pointed out during the early stages of the...
... the acquisition of reading and the effectiveness of different approaches to the teaching of reading, and the implications of this research for teachingpractice. The most recent of these reports is the Report ... that theyincluded systematic teaching of phonicsas a part of their teaching program.Again there was a difference between the pilot andthe control schools interms ofthe proportion of teachers ... term of school (effect size of 12), andthe structured program groupscoring higher on the teacherassessment of reading skills at the end of the first year of school (effect size of .07).There...
... hypogondoropic-hypogonadism. The increased aromatase activity of the visceral and peripheral fat further diminishes the levels of testosterone and increases the levels of estradiol(E2), which further contributes ... to assess obesity and this, inaddition to the age ofthe cohort being studied, hasinfluenced the strength ofthe correlation between ED and obesity. The International Index of Erectile Function ... pathophysiologicalmechanisms of obesity-induced androgen deficiency and hypogonadism-induced obesity remain the subject of intense investigation.Several hypotheses have discussed the relationship of androgen deficiency and...
... ofthe first 88amino acids of PPI1 may participate in the interactionwith the H+-ATPase and makes PPI1588His6a suitabletool to study the mechanism of action of PPI1. The analysis ofthe ... coli strain XL10 and the frame andthe identity ofthe cloned fragment verified bysequencing. The construct with the N-terminal portion of PPI1 has been previously described [22]. The DNA fragment ... 14-3-3s.Results The C-terminus of isoform 1 ofthe PM H+-ATPase of A. thaliana (AHA1) interacts with the first 88 aminoacids of PPI1 [22], indicating that the PM H+-ATPasebinding site of PPI1 is...
... at the time of chloroplast origin had poorly definedinteractions between Cyt f and plastocyanin and/ or plasto-cyanin and photosystem I, and subsequently the nature of the interactions in the ... Hence, the dependence of k2 of wild-type and all mutants on the concentration of MgCl2was investigated at 278, 283, 288, 293 and 298 K.Table 1. Kinetic and thermodynamic parameters ofthe reaction ... Hencefor both organisms, the changes in DSà of the electronicfactor would have the same sign as the measured trend.Further discussion ofthe effects of ionic strength onthermodynamic parameters...
... of ISP and the extramembranous cd2 helix of cytochrome b areimportant for maintaining the structure ofthe hinge region and, by consequence, the movement ofthe headgroup and the integrity of ... region andthe cytochrome bextramembranous cd2 helix is important for maintaining the structure ofthe hinge region and, by consequence, the movement ofthe headgroup andthe integrity ofthe enzyme.Keywords: ... below.Instability ofthe mutant enzymeFurther analysis ofthe kinetic parameters ofthe G167Emutant was hindered by rapid inhibition ofthe activity of the bc1complex during the assay, which...
... 95/46/EC (Directive 95/46/EC of the European Parliament andofthe Council on the protection of individuals with regard to the processing of personal data and onxxxiv table ofconventionsArt. 25 6, ... VII 59–60, 104, 168–78Charter ofthe International Military Tribunal, Annex to the Agreementfor the Prosecution and Punishment ofthe Major War Criminals of the European Axis (London Agreement), ... Protocols of 8 June1977 to the Geneva Conventions of 12 August 1949, Section I: ProtocolAdditional to the GenevaConventions of 12 August 1949, and relating to the Protection of Victims of International...
... Moreover,spontaneous heterodimerization in the absence of ligand between EcR and USP fragments requires neither the hingeregion nor the F domain of EcR, and even helices 11 and 12 of its LBD are dispensible ... in the absence of ligand and whether ligand promotes dimerization. We found thatC-terminal protein fragments that comprised the ligandbinding, but not the DNA binding domain of EcR and USPandwhichwereequippedwiththeactivationorDNAbinding ... The primary purpose of this work is to address the possibility that EcR and USP are capable of dimerizationin the absence of a bipartite EcRE and to monitor the potential influence of ecdysteroid...
... capacity and also modulating the catalytic properties ofthe enzyme [19]. To extend the information about the role ofthe noncatalyticSBD regions and their effect on the C-terminal CD,we further ... protein makes this isoform a potential target for the manipulation ofthe level and quality of plantstarch. However, little is known about the role of SSIII in starch synthesis andthe structure–functionrelationship ... D(316–344) and D(495–535) for the interaction betweenthe N-terminal SBDs and CD.Our data also show that the full integrity of the starch-binding capacity, particularly ofthe D2 domain,modulates the...
... the body ofthe cell, andthe substrate at the basal surface of the ECs. Interestingly, forces acting at one surfacemay be propagated internally or even to other sur-faces ofthe cell, or they ... flow and effects from other neighboringcells and matrix. The biophysical aspects ofthe endo-thelium through which the leukocytes transmigrate, inaddition to the biophysical aspects ofthe ... in the healthyimmune response and in the development of disease. Itis evident that the process involves a transmission of physical forces as the leukocytes pass through the endothelium. The...
... A˚ of com-pound 3, one between Oc1 of Thr218 (EL-2) and the backbone oxygen of Phe4 (2.94 A˚), and one between the hydroxyl oxygen ofthe Tyr1 group and OAla240(TMH V) of 2.66 A˚. The ... description of the binding mode andthe electronic and steric proper-ties ofthe c[YpwFG] ligand.ResultsSynthesis and pharmacological characterization of the cyclopeptides c[YpwFXaa]We synthesized ... Cys and His) located on the surface ofthe bind-ing site, and this polarization effect can be obtained byusing the QM description ofthe ligand. Looking at the electronic structure ofthe ligands...
... andthe humidity of the paper itself. Humidity balance, then, is the relation between the humidity of a material andthe humidity ofthe surroundingair. As long as both values are balanced, the ... blistering, such as the type of binding agents and coating pigments used, the amount of binding agents contained in the paper andthe amount of coating used, andthe degree to which the surface has ... figure to the right). The main sources of breaking in the fold are the extremetemperatures the paper is subjected to in the drying oven and the pressure applied in the folding unit. The single...