ose epithelial mesenchymal transition and inclusion cysts

... Materials and Methods 24 Chapter Results and Discussion 3.1 PRL-3 promotes Epithelial- Mesenchymal Transition 3.1.1 PRL-3 reduces paxillin, phosphorylated paxillin-Tyr31, and vinculin ... Transformed cell morphology and altered cell adhesion are reminiscent of Epithelial Mesenchymal Transition, which enables cells to detach from their structured epithelial layers and become more migratory ... properties, such as motility, invasiveness and tumorigenicity Two important features of cancer progression are Epithelial- Mesenchymal Transition (EMT) and evasion of programmed cell death EMT is...

Ngày tải lên: 16/10/2015, 15:37

... E-cadherin genes and initiate epithelial- mesenchymal transition Complexes of Smad7 and Smurf1 or Smurf2 promote ubiquination and degradation of activated receptors limiting the intensity and duration ... environment on neoplasia The role of the ECM and stroma in cancer Drivers and mediators of epithelial- mesenchymal transition (EMT) Early stage tumor cells maintain epithelial properties similar to the ... infiltration, cytokine and growth factor release, and formation of a scaffold composed of collagens and other matrix molecules into which fibroblasts enter and proliferate Healing and fibrotic scaring...

Ngày tải lên: 09/08/2014, 08:22

... 4.1.1 Properties of epithelial cells and mesenchymal cells 63 4.1.2 Epithelial- Mesenchymal Transition 64 4.1.3 Regulatory factors controlling EMT 66 4.1.4 TGF-β and Wnt signaling pathways are important ... 71 Figure 4.2 P1 and P2 colonies displayed markedly different morphology and migration 73 Figure 4.3 Expression levels of epithelial- , EMT- and mesenchymalrelated markers in P1 and P2 cells 75 ... TGF-β signaling promotes cancer progression and metastasis via epithelial- mesenchymal transition (EMT), angiogenesis and immuno-suppression (Wakefield and Roberts, 2002) 11 Interestingly, some...

Ngày tải lên: 09/09/2015, 18:57

... epithelial- mesenchymal transition in alveolar epithelial cells Respir Res 2007, 8:31 31 Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ: Collagen I promotes epithelial- to -mesenchymal transition ... E-cadherin and N-cadherin levels, and collagen I, CTGF and MMP-2 gene expression These markers facilitate identification of cells along the spectrum of transition from epithelial to mesenchymal ... E-cadherin and N-cadherin expression by PPARg ligands (A) Effect of TGF-b1 or PPARg ligands on expression of epithelial marker E-cad (n = 4) (B) Effect of TGF-b1 or PPARg ligands on expression of mesenchymal...

Ngày tải lên: 12/08/2014, 11:20

... Appendix B: Buffers and Solutions 148   vi SUMMARY In recent years, the epithelial- mesenchymal transition (EMT), in which epithelial cells lose their epithelial characteristics and gain mesenchymal features, ... transient and reversible, which is why the preferred term is now transition, as opposed to transformation (EMT denotes epithelial- mesenchymal transition; MET denotes mesenchymal -epithelial transition) ... Epithelial- mesenchymal transition (EMT) is defined by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype EMT is thought to occur during cancer progression and...

Ngày tải lên: 05/10/2015, 21:24

... architectural differences between two main types of odontogenic cysts: radicular cysts and keratocysts, and 2) between the solitary and BCN syndrome keratocyst subtypes This was investigated by ... (pooled) keratocysts and radicular cyst categories OK: solitary odontogenic keratocysts, Radicular: radicular cysts, BCNS OK: Basal cell naevus syndrome keratocysts, OKs: keratocysts (pooled, ... statistically significant differences in the epithelial architecture of OKs and radicular cysts and between the subtypes of OKs Radicular cysts have on average more layers and their number varies more than...

Ngày tải lên: 11/08/2014, 23:22

... proposed as a source of lung myofibroblasts [10-12] Recently, the hypothesis that myofibroblasts arise from epithelial cells through epithelial to mesenchymal transition (EMT) has been proposed ... collagen I and III as well as fibronectinEDA and tenascin C Our results shown above suggested that bronchial epithelial cells can transition into a mesenchymal- like phenotype upon TGFβ1treatment and ... epithelial to mesenchymal cell transition (EMT) Respir Res 2005, 6:56 Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z: Induction of epithelial- mesenchymal transition...

Ngày tải lên: 12/08/2014, 14:20

... alveolar epithelial to mesenchymal cell transition (EMT) Respir Res 2005, 6:56 Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z: Induction of epithelial- mesenchymal ... screening and breeding, histological works and drafted the manuscript LLY carried out the microinjections and transgenic screening and breeding LC participated in the histological work and mice ... bleomycin (BLM) administration and to act as myofibroblast progenitors [6] More recently, alveolar epithelial cells (AECs) have been shown to undergo epithelial to mesenchymal transition (EMT) to produce...

Ngày tải lên: 12/08/2014, 16:20

Ngày tải lên: 18/02/2014, 11:20

... tasks and milestones, and program and budget The Chief Information Officer has responsibility for ensuring a coherent and timely transition, establishing and maintaining the overall departmental transition ... policies, timelines, and methods for transitioning to IPv6 These efforts include creating a transition office, developing guidance and policies, drafting transition plans, and fielding a pilot ... Policies and Enforcement Mechanisms Developing and establishing IPv6 transition policies and enforcement mechanisms are important considerations for ensuring an efficient and effective transition...

Ngày tải lên: 23/03/2014, 03:20

... for Reconstruction and Development (EBRD) discerns: Central and Eastern Europe and the Baltic States, South Eastern Europe, and the 14 Taxation and Public Finance in Transition and Developing Economies ... Taxation and Public Finance in Transition and Developing Economies, doi: 10.1007/978-0-387-25712-9_1, © Springer Science + Business Media, LLC 2008 Taxation and Public Finance in Transition and Developing ... Taxation and Public Finance in Transition and Developing Economies Taxation and Public Finance in Transition and Developing Economies Edited by Robert W McGee...

Ngày tải lên: 23/03/2014, 11:20

... 94 Dyslexia and Inclusion Inclusion Inclusion – meeting needs Principles and practices of inclusion Five signposts to inclusion Key factors Comment Conclusion Further Information and Contacts ... detection of onset and rime at rhyme judgement and production; and phoneme segmentation such as blending, detection and deletion of initial and final phonemes 15 Dyslexia and Inclusion Phonological ... text and the font characteristics and font size Dyslexia and Inclusion Connections The symbol in the diagram above between the eye and the ear represents the neurological basis for dyslexia and...

Ngày tải lên: 03/06/2014, 01:55

... TRANSITION AND CHALLENGE This page intentionally left blank Transition and Challenge China’s Population at the Beginning of the 21st Century Edited by ZHONGWEI ZHAO AND FEI GUO 1 ... Patterns, and Their Sex Differentials 10.5 Conclusions 11 Population Ageing: Challenges, Opportunities, and Institutions Feng Wang and Andrew Mason 11.1 Population Ageing: National and Sub-National ... Planning, and Population Changes Isabelle Attané 15.1 Cultural Integration and Development 15.2 Family Planning and Fertility Decline 15.3 Recent Changes in Mortality, Age and Sex Composition, and...

Ngày tải lên: 11/06/2014, 01:28

... pore size, Nunc, Germany) and covered with DMEM with 0.1% BSA After 24 h × 104 pluripotent mesenchymal cells (C2C12) were added to the upper chamber and cultured under standard conditions For positive ... rinsing the cells the freshly prepared AP-buffer was added and Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2007, 2:27 incubated for 30 at 37°C The absorbance ... IGF-I and BMP-2 Two different cell types were used to investigate the effect of the different growth factors In both cell types, primary human osteoblast like cells and a murine pluripotent mesenchymal...

Ngày tải lên: 20/06/2014, 01:20

... Influences of phase transition and microstructure on dielectric properties of Bi0.5Na0.5Zr1-xTixO3 ceramics Panupong Jaiban1, Ampika Rachakom1, Sukanda Jiansirisomboon1,2, and Anucha Watcharapasorn*1,2 ... purpose of this work is to investigate influences of the occupancy of Ti4+ ions at the B-site of Zr4+ host ions with Zr/Ti ratios of 0.7:0.3, 0.6:0.4, 0.5:0.5, and 0.4:0.6 on phase transition and ... experiments, analysis, and writing of the manuscript AR carried out the crystal structure investigation of the specimens SJ and AW participated in the conception and design of the study and revised the...

Ngày tải lên: 20/06/2014, 23:20

... supported by the Thailand Research Fund (TRF) and the National Research University Project under Thailand’s Office of the Higher Education Commission (OHEC) The Faculty of Science and the Graduate ... investigation of the specimens SJ and AW participated in the conception and design of the study and revised the manuscript for important intellectual content All authors read and approved the final version ... samples sintered at 950°C were measured at frequencies of 1, 10, and 100 kHz Page of Table Dielectric constant and loss of the BNZT and BNZ ceramics x εra tanδa (%) εrb tanδb (%) εrc tanδc (%) Reference...

Ngày tải lên: 21/06/2014, 17:20

... statistical analysis, mainly composed the manuscript and performed administrational and institutional work BP is the Head of Department and reviewed the manuscript and gave scientific impact UT ... two major classes: A-B2 and B3-C eMasaoka and WHO did show joint effects with pseudocapsula and were therefore not taken to further analysis geon to evaluate resectability and estimate patient's ... critical review of surgical records and pathology reports Further more, R-, Nand M-Status was classified in addition to a local infiltration of vessels and pericardium and the presence of a pseudocapsula...

Ngày tải lên: 10/08/2014, 10:20

... treated with increasing doses and exposure times of LA, and subjected to trypan blue exclusion assay to measure the cell growth and viability LA treatment resulted in dose- and time-dependent inhibition ... affects on cell growth and viability, only cells exposed to 2.5 and mM LA for 24 and 48 h were analyzed The percentage of cells in G1, S, and G2 phases were calculated and presented as histograms ... increasing dose of LA (E) Subcellular distribution of immunoreactive AIF and Cyt C in the cytosol, mitochondria and nucleus in control and 24 and 48 h LA-treated HL-60 cells Actin and histone...

Ngày tải lên: 10/08/2014, 22:20

... Breeding and Husbandry, 24908 Kiel, Germany Authors’ contributions ZL conducted the analyses and wrote the manuscript FS prepared the genomic data FR and SR helped check the results and suggested ... reference bulls in this run and the February 2010 run Reference bulls in the February 2010 run but not in this run Common candidates in this run and the February 2010 run Candidates with a sire in ... similar scale of variances for GEBV and EBV, making them more comparable and consequently resulting in a more accurate joint ranking of genomic selection candidates and proven bulls However, the problem...

Ngày tải lên: 14/08/2014, 13:21

... scheduled for the 13 Robert Sands, “Anthropology and Sport” in, Robert Sands (ed.) Anthropology, Sport, and Culture, (Westport, CT: Bergin and Garvey, 1999): 14 Andrei S Markovits and Steven L Hellerman, ... 2007: 18 Gerardo A Sandoval and Ricardo G Abad, “Sports and the Filipino: A Love Affair,” Social Weather Bulletin Vol 97, Nos 3-4 (February 1997): 3-4 19 Sandoval and Abad, “Sports and the Filipino,” ... political and economic issues Sports are, in some ways, microcosms of the societies in which they 11 are located, and a closer look into them “produces a blueprint of those important and valued...

Ngày tải lên: 12/09/2015, 09:22