... 9:55 They form part of a feedback mechanism, each directly affecting the expression of the other: AtLhy.p is a repressor of AtTOC1, and AtToc1.p is required for the expression of AtLHY [8] The ... consistent with it being a promoter of flowering, the profiles of abundance of the TaVRN2 transcript were not what would be expected of a repressor of flowering, and not fit the model presented in Additional ... case the lighter shade represents crown tissue expressed; regardless of the low abundance of the TaVRN3 transcript, transcripts of TaVRN1 exhibited an increase over the time-course In the light of...
Ngày tải lên: 12/08/2014, 03:20
... phase G2/M phase G1/G0 phase S phase G2/M phase G1/G0 phase Phase of HeLa cell cycle Figure Phase enriched expression of the miR-17-92 locus Phase enriched expression of the miR-17-92 locus (a) ... Many of these targets are known cell cycle regulators, although none of these interactions are sufficient to explain the oncogenic potential of this locus The specific mechanisms of either the ... involved in the G1 to S phase transition Cloonan et al R127.5 Over-expression of miR-17-5p alters the cell cycle profile of HEK293T cells We used flow cytometry to examine the DNA profiles of asynchronous...
Ngày tải lên: 14/08/2014, 20:22
Tài liệu Đề tài " Geometry of the uniform spanning forest: Transitions in dimensions 4, 8, 12, . . . " pptx
... be the union of Fn−1 with the loop-erasure of Xn Then F := ∞ Fn has the distribution of the n=1 (wired) USF on G The edges in F inherit the orientation from the loop-erased walks creating them, ... further condition on the occurrence of S, then we should also contract the edges in K1 and delete the edges in K2 Therefore, conditionally on ΥR and the occurrence of S, the path γR has the ... apply the Cauchy-Schwarz inequality in the form E[Suz ]2 P[Suz > 0] ≥ E[Suz ] The estimates (2.6) and (2.7) then yield the assertion of the lemma uz Corollary 2.9 Under the assumptions of Theorem...
Ngày tải lên: 14/02/2014, 17:20
Báo cáo Y học: Identification of residues critical for activity of the wound-induced leucine aminopeptidase (LAP-A) of tomato pptx
... weak The peptide is further stabilized at the active site by the interaction of the N-terminal amine of the P1 residue with a carboxylate oxygen of Asp273 (Asp366), the carbonyl oxygen of the ... identified the residues important for LAP catalysis and coordination of the two zinc ions in the active site The impact of the mutations on the tomato LAP enzyme must be viewed in the context of these ... binding of the carboxyl oxygen of the P1 residue and stabilization of the gem-diolate transition state The Ala substitution mutant (K354A) of the tomato His6–LAP-A was not evaluated in the tomato...
Ngày tải lên: 08/03/2014, 23:20
The first three minutes a modern view of the origin of the universe s weinberg
... mostly with the large-scale structure of the present universe: the debate over the extragalactic nature of the spiral nebulae; the discovery of the red shifts of distant galaxies and their dependence ... imaginable of the origin of the universe Just as in the Younger Edda, there is an embarrassing vagueness about the very beginning, the first hundredth of a second or so Also, there is the unwelcome ... shift, due to the motion of the star away from or towards the earth For instance, the wavelength of every dark line in the spectrum of the star Capella is longer than the wavelength of the corresponding...
Ngày tải lên: 17/03/2014, 13:35
Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR pptx
... proteins bound to the beads in the presence of dsRNA and hep lanes, proteins bound to the beads in the presence of heparin The names of the proteins are indicated below the panels and the additional ... of PKR mutants and the mutant name is shown at the bottom of the panels (C) dsRNA-binding activity of the mutants The dsRNA-binding activity of the point mutants was tested by their binding to ... extracts (Fig 6C) and all of the mutants were expressed at the same level in HT1080 cells The kinase activity of the mutants was further tested by assaying the effect of their expression on yeast...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Mitochondrial connection to the origin of the eukaryotic cell pdf
... for the origin of the nucleus, endomembrane, and cytoskeleton Nonetheless, phylogenetic methods can still be applied to proteins, the appearance of which might have accompanied the origin of the ... convergent) origin of the insert itself (Fig 3B) Apart from the origin of the proeukaryote, ValRS data shed light on the intriguing question of the extent and evolutionary significance of LGT [52,53,75,76] ... proteins by means of paralogous multiplication may indicate the origin of ER per se Similarly, multiplication of the enzymes of DNA metabolism may be tied to the origin of the nucleus with multiple...
Ngày tải lên: 31/03/2014, 01:20
Báo cáo Y học: Ascidian arrestin (Ci-arr), the origin of the visual and nonvisual arrestins of vertebrate pdf
... position of the intron to the vertebrate type of arrestin (Fig 1) Therefore, it may be presumed that the function was lost in vertebrate visual arrestin during the evolution The branch length of the ... constructed the corresponding mutant for Ci-Arr (V55D) This mutant, however, showed that the extent of the internalization was almost the same as that of the control (Fig 2B) in spite of the same ... Ci-Arr enhances the internalization of b2-ARs by the mechanism independent of the function of endogenous b-arrestin or related proteins To know the expression pattern of Ci-arr gene in the larva,...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: A comparison of the urea-induced unfolding of apo¯avodoxin and ¯avodoxin from Desulfovibrio vulgaris potx
... increases the slope in the transition region of the unfolding curve for apo¯avodoxin but it has no effect on the slope of the curve for ¯avodoxin Furthermore, the slope of the curve for the holoprotein ... plots of the logarithm of the equilibrium constant (Kapp) for the unfolding of apo¯avodoxin calculated at 2.94 M (j) and 3.43 M (d) urea vs the logarithm of the mean activity of NaCl (ln a) the ... on the ionic composition of the solution The change in protein ¯uorescence as a function of the concentration of urea is consistent with a two-state model of unfolding, as are the kinetics of the...
Ngày tải lên: 31/03/2014, 15:20
molecular dynamics studies of ultrafast laser induced phase and structural change in crystalline silicon
... the surface of the sample starts to melt at about 1780 K but the rest part of thin film remains as solid due to the higher surface energy of the atoms at the surface Besides that, at 1780 K, the ... about the end of the laser pulse The melt depth reaches a maximum depth of 2.68 nm, and then resolidification starts It is noted that after the melted region is completed solidified, some of the ... for the study of ultrafast laser heating For the purpose of allowing the motions of atoms at the surface, extra 480 empty unit cells and 120 empty unit cells, which are the empty space for the...
Ngày tải lên: 06/05/2014, 08:54
led zeppelin. the origin of the species how, why and where it all began
... he told them, they’d be replaced - with the exception of X-factor Dave 48 THE ORIGIN OF THE SPECIES - with hired hands quicker off the mark The Cruisers could then learn the song off the record ... the loftiest plateaux of pop in the teeth of adult disapproval of the noise, gibberish and loutish excesses of the rock ‘n’ roll epidemic from across the Atlantic of which Berry was part Furthermore, ... suites and the privacy of their own homes, the group could afford to retire from public performance for over a year after the issue of 1973’s Houses Of The Holy This enabled the foundation of their...
Ngày tải lên: 04/06/2014, 15:26
Báo cáo hóa học: " Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade" pot
... In addition to the crucial function of PB1, the PB2 subunit is responsible for recognition and binding of the cap structure of host mRNAs [32,33] The role of the PA subunit in the transcription ... expression The relative polymerase activity of the wild type H3N2 was higher than that of the wild type H1N1 The values obtained from the transfections comprising the wild type system of each virus ... on the cell surface We recently showed that membrane accumulation of the HA protein triggers the activation of MAPK signaling [24] In this study, we therefore analyzed the expression of HA on the...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " The origin of the red emission in n-ZnO nanotubes/p-GaN white light emitting diodes" pdf
... the ZnO NTs to prevent them from reaching the p-type substrate, thereby helping to prevent the carrier cross talk among the nanotubes To form the top contacts, the tip of the ZnO NTs were exposed ... technique after the deposition of the insulating photo-resist layer Non-alloyed Pt/Al metal system was used to form the ohmic contacts to the ZnO NTs The thicknesses of the Pt and the Al layers ... specific contact resistance of 1.2 × 10-5 Ω cm-2 [28] The diameter of the top contact was about 0.58 mm Results and discussions Figure 1a,b shows the images of the top of the ZnO nanotubes before...
Ngày tải lên: 21/06/2014, 05:20
Báo cáo hóa học: " On the Chemical Origin of the Gap Bowing in (GaAs)12xGe2x Alloys: A Combined DFT–QSGW Stud" pptx
... descriptors of the ZB—diamond phase transition than thermodynamic ones: the latter not take into account the nonuniqueness of the critical composition xc as a function of kinetic growth; they require ... www.webelements.com)] In the alloy I the number of ‘‘bad bonds’’ [7, 8], i.e., the number of III–IV and IV–V nearest neighbors, is 12, or 37.5% of the total According to the Bader analysis [57–59], in the pure ... that the IIb structure corresponds to the high concentration limit of isolated couples.) According to phase transition theory, the symmetry lowering for the two intermediate systems is the fingerprint...
Ngày tải lên: 22/06/2014, 00:20
Báo cáo khoa học: "Mucin pattern reflects the origin of the adenocarcinoma in Barrett''''s esophagus: a retrospective clinical and laboratorial study" ppsx
... pattern predominance in the adjacent epithelium compared to the mucin tumour expression Discussion The extension of the columnar epithelium in the esophagus is related to the risk of malignant transformation ... the tumors There was an association between the predominance of mucin expressed in the adjacent epithelium and the pattern of mucin expression in the tumors, may indicating the route of carcinogenesis ... immunohistochemistry of the columnar epithelium of the oesophagus (Barrett's oesophagus) Virchows Archiv A Pathol Anat 1989, 414:359-63 Nakamura K, Sugano H, Takagi K: Carcinoma of the stomach in the incipient phase: ...
Ngày tải lên: 09/08/2014, 04:21
báo cáo khoa học: "The in Southern African Nguni cattle. identification, occurrence and origin of the translocation" pot
... favour of the removal of translocation carrying cattle from stud herds The aim of this study was to investigate the origin, identification and occurrence of the translocation in the Nguni herds The ... Enlargement of the R-banded chromosomes enables the identification of the participating chromosomes as numbers and 29 The C-banded metaphase spread (fig 2) shows the centromeric regions of the translocation ... The m Results Screening of the metaphase spreads confirmed the presence of 60 chromosomes, consisting of 29 acrocentric autosomal pairs and pair of sex chromosomes This is in agreement with the...
Ngày tải lên: 09/08/2014, 22:23
báo cáo khoa học: "Anomalous origin of the left coronary artery from the pulmonary artery associated with an accessory atrioventricular pathway and managed successfully with surgical and interventional electrophysiological treatment: a case report" docx
... the development of the ALCAPA anomaly: the older embryological theory of Abrikossoff abnormal septation of conotruncus into the aorta and pulmonary artery, and the newer theory of Hackensellner ... shallower lesions The disadvantages of this method are the larger size of the catheter and its stiffness We elected to use RF energy and minimized the number of catheters used and the number, power, ... to develop anlagen of the coronary arteries The various anomalies are explained on the basis of faulty involution or persistence of one or several of these anlagen From the other side, by definition,...
Ngày tải lên: 10/08/2014, 23:20
Báo cáo y học: " Origin of the blood hyperserotonemia of autism Skirmantas Janušonis" pps
... kinetics of the human gut SERT.) The 5-HT uptake rate constant of one platelet The Vmax and and Km values were obtained by weighting the medians of each of the three groups of [18] by the number of ... and/or the liver (Fig 1) 16 The gain of the regulation of the gut 5-HT release rate that is controlled by extracellular 5-HT concentration in the gut wall 17 The gain of the regulation of the gut ... thickness of blood capillaries in the gut 14 The proportion of the total cardiac output routed to the gut and/or the liver (Fig 1) 15 The proportion of the total cardiac output not routed to the gut...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "Mechanism of the chromosome-induced polar body extrusion in mouse eggs" potx
... may maximize the constriction of the contractile ring at the shoulder region of the cortical protrusion, leading to the final abscission of polar body Coordination of the chromosome -induced cortical ... into the center of the eggs to induce spindle formation farther away from the cortex (Figure 4A) After inducing anaphase by SrCl2, the DNA bead- A B MII spindle underwent metaphase-anaphase transition ... however, whether the induction of spindle and cortical polarity requires the same chromosome signal We have shown that DNA beads injected into the cortex of the MII eggs behaved as the in vivo...
Ngày tải lên: 13/08/2014, 18:21
transitions during adolescence a qualitative exploration of the developmental and healthcare transition experiences of adolescents with epilepsy
... determine their experiences of transition and their ideas for improving transition services They concluded that the inclusion of these young people was invaluable to understanding their specific ... described how they cope with their epilepsy It is made up of four subthemes: Striving for Normalcy, Feeling Safe, Minimising the Impact and External Locus of Control The interpretation of these themes ... Giving these young people the opportunity to describe their understanding and experiences of transition and the concurrent impact on their development may allow for a better understanding of their...
Ngày tải lên: 22/12/2014, 16:40