opposite effects of cancer treatment and regular pa

... separation its recession limb and determining only the runoff constituents and their comparison also in the process of time Similarly, the influence of land use changes 310 on the ratio of runoff ... slow runoff (65–80%), higher proportion of accelerated runoff (17–30%) and a little lower proportion of rapid runoff (2–4%) The higher proportion of accelerated runoff indicates the runoff of increased ... Kemel 1996) First, the effects of drainage treatment and stand growth on changes in runoff were analyzed and interpreted employing the frequencies of mean daily streamflows and master hydrograph...

Ngày tải lên: 07/08/2014, 03:22

... and flow cytometry were analyzed using two-tailed Student t-test with assumption of different variance Significance of differences in percentage of viremia, antibody and the results of histopathology ... cells of the sinusoids and Kupffer cells (arrows) Bar=100 µm simple measure of atrophic changes in the bursa of Fabricius and thymus might be useful in determining the pathotype classification of ... LM, Venugopal K Current status of diagnosis, epidemiology and control of ALV-J In: Proceedings of the avain tumour viruses symposium, pp 5862 Reno, Nevada: American Association of Avian Pathologists...

Ngày tải lên: 07/08/2014, 17:22

... clinical effects of pollen exposure, as well as effects of a nasal glucocorticoid treatment on both symptoms of rhinitis, eosinophilia and expression of several cytokines [2,5] Materials and methods ... was expressed as a percentage of total tissue area GraphPad (GraphPad Software, Inc CA, USA) was used for the non-parametric statistical analysis of the percentage of positive staining in tissues ... nasal mucosa of healthy and AR subjects was predominantly in the nucleus of the epithelial and endothelial cells (glandular and vesicular) Similarly, OPN expression has Figure Percentage of osteopontin...

Ngày tải lên: 08/08/2014, 21:20

... possible that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects (deterioration of psychosis) of sertarline in this ... AT, JM and TK contributed to the clinical and rating evaluations during the follow-up periods KH conceived of the study and participated in its study and coordination All authors read and approved ... effective in the treatment of psychotic major depression, and the switch to sertraline worsened the psychotic symptoms in the patient The mechanisms underlying the opposite effects of these two SSRIs...

Ngày tải lên: 08/08/2014, 23:21

... October 2008; and University of Chicago liquidity, credit risk, and extreme events conference, 2009; and seminars at Norges Bank, National Bank of Poland, Helsinki School of Economics, and the universities ... 80.45% of the 78 auctions Cooperative bidders participate in the fewest number of auctions, only 27.51% As seen by comparing Tables and 2, the cooperative sector also has the smallest participation ... Imbalance×ln(assets) has a mean of 7,543 and a standard deviation of around three times that The size ratio averages to 1.24 and has a standard deviation of 1.75 Its minimum is 0.2 and its maximum is 15.8,...

Ngày tải lên: 15/03/2014, 10:20

... analysis of the synthesis and release of DA by RPE cells HPLC analysis of the synthesis and release of DA by RPE cells.(A) HPLC analysis of standard of DA, 3,4-dihydroxyphenylacetic acid (DOPAC) and ... designed by MM and WL and were performed by MM, XL, and XF Human RPE cells were separated and cultured by QG DY, LL and SC gave advises on the work and helped in the interpretation of the data WL ... http://www.translational-medicine.com/content/7/1/53 segment and lens were separated and discarded The neural retina was detached and layer of RPE cells were separated from the choroid The layer of RPE cells was dissociated...

Ngày tải lên: 18/06/2014, 15:20

... obtained from the patients and the study protocol was approved by the ethics committee of Zhongnan Hospital of Wuhan University Major clinico-pathological features Page of 11 of these patients were ... malignant gland compared to normal gland, especially nearby the BM (Figure 2C) High density of macrophages was observed at the juncture of cancer cells and stroma where BM integrity of gastric gland ... however, is the lack of appreciation of the “temporal and spatial coevolution of cancer and its environment”, which is the real context of tumor progression [17] Peng et al Journal of Translational...

Ngày tải lên: 18/06/2014, 16:20

... pastoralists due to competition for scarce pasture and water Pasture and water conflicts have long been part of the socio-cultural pattern of the pastoral communities in Kenya The communal land ... however, pasture and water around the settled areas steadily decreases, leading to emaciation and loss of livestock Traditionally, whenever scarcity of pasture and water Page of 16 Kaimba et al Pastoralism: ... rustling leads to loss of livestock, destruction of property, and injury and sometimes death of people, which are the main Page 11 of 16 Kaimba et al Pastoralism: Research, Policy and Practice 2011,...

Ngày tải lên: 20/06/2014, 23:20

... and significant improvement of ICU monitoring (in particular of the patient’s hydration status) and treatment (more rapid and adequate resuscitation of severe sepsis and shock and avoidance of ... HS and RJ conceived and wrote the review VVG and JT participated in literature search and selected appropriate articles PMH participated in design, coordination, and writing All authors read and ... article as: Spapen et al.: Renal and neurological side effects of colistin in critically ill patients Annals of Intensive Care 2011 1:14 Page of Submit your manuscript to a journal and benefit from:...

Ngày tải lên: 21/06/2014, 03:20

... benefit One of the challenges of cancer treatment is to use the various treatment modalities alone and together in a fashion that maximizes the chances for patient benefit Cancer treatments are ... doses of cytokines such as interleukin (IL) are all used in certain settings where 100% of the patients will experience toxicity and side effects from the intervention and only a fraction of the patients ... radiotherapy-, and internal medicine–related areas of expertise Treatments for patients with hematologic malignancies are often shared by hematologists and medical oncologists In many ways, cancer mimics...

Ngày tải lên: 07/07/2014, 01:20

... tumor and reduce its size can result in an increase in the growth fraction and an increase in growth rate Principles of Cancer Surgery Surgery is used in cancer prevention, diagnosis, staging, treatment ... a 20% risk of developing breast cancer over the next years as a threshold However, patient fears play a major role in defining candidates for cancer prevention surgery Counseling and education ... localized and metastatic disease), palliation, and rehabilitation Prophylaxis Cancer can be prevented by surgery in people who have premalignant lesions resected (e.g., premalignant lesions of skin,...

Ngày tải lên: 07/07/2014, 01:20

... information for treatment planning and may determine the extent and nature of primary cancer treatment Treatment Surgery is the most effective means of treating cancer Today about 40% of cancer patients ... surgery is also being employed to spare organ function, as in larynx and bladder cancer The magnitude of operations necessary to optimally control and cure cancer has also been diminished by ... curative in a subset of patients with metastatic disease Patients with lung metastases from osteosarcoma may be cured by resection of the lung lesions In patients with colon cancer who have fewer...

Ngày tải lên: 07/07/2014, 01:20

... successful therapy Plastic and reconstructive surgery can correct the effects of disfiguring primary treatment Principles of Radiation Therapy Physical Properties and Biologic Effects Exposure to ionizing ... any tissue in its path; its selectivity for cancer cells may be due to defects in a cancer cell's ability to repair sublethal DNA and other damage Radiation causes breaks in DNA and generates free ... sun and other cosmic sources, the ground, the air we breathe, the food we ingest, and from within our bodies Radiation therapy uses radiation to treat cancer Radiation is a physical form of treatment...

Ngày tải lên: 07/07/2014, 01:20

... human form and substance Radiation dose has three determinants: total absorbed dose, number of fractions, and time A frequent error is to omit the number of fractions and the duration of treatment ... are generated from decay of atomic nuclei in radioisotopes such as cobalt and radium These waves behave biologically as packets of energy, called photons Particulate forms of radiation are also ... produces a skin-sparing effect, more homogeneous distribution of the radiation energy, and greater deposit of the energy in the tumor, or target volume The tissues that the beam passes through...

Ngày tải lên: 07/07/2014, 01:20

... number of diseases, including breast cancer, Hodgkin's disease, head and neck cancer, prostate cancer, and gynecologic cancers Radiation therapy can also palliate disease symptoms in a variety of ... relief of bone pain from metastatic disease, control of brain metastases, reversal of spinal cord compression and superior vena caval obstruction, shrinkage of painful masses, and opening of threatened ... die Hematoporphyrins and light are being used with increasing frequency to treat skin cancer; ovarian cancer; and cancers of the lung, colon, rectum, and esophagus Palliation of recurrent locally...

Ngày tải lên: 07/07/2014, 01:20

... capitalize on the biochemical pathways underlying estrogen and androgen function and action as a therapeutic basis for approaching patients with tumors of breast, prostate, uterus, and ovarian origin Biologic ... some treatment; PS3, disabling symptoms, but allowing ambulation for >50% of the day; PS4, ambulation

Ngày tải lên: 07/07/2014, 01:20

... Chemotherapy may be employed after the failure of these modalities to eradicate a local tumor or as part of multimodality approaches to offer primary treatment to a clinically localized tumor In ... metastatic cancers If a tumor is localized to a single site, serious consideration of surgery or primary radiation therapy should be given, as these treatment modalities may be curative as local treatments ... Chemotherapy agents may be used for the treatment of active, clinically apparent cancer Table 81-1, A lists those tumors considered curable by conventionally...

Ngày tải lên: 07/07/2014, 01:20

... Modulation of apoptosis by manipulation of signal transduction pathways has emerged as a basis for understanding the actions of drugs and designing new strategies to improve their use A general view of ... least an increased time to further progression of disease Active efforts are being made to quantitate effects of anticancer agents on quality of life Cancer drug clinical trials conventionally use ... conducted, molecular analysis of human tumors more precisely defines targets expressed in a patient's tumor and should allow patient selection to enrich all trial phases with patients potentially responsive...

Ngày tải lên: 07/07/2014, 01:20

... antagonize the action of bcl2 Damaged mitochondria release cytochrome C and apoptosis-activating factor (APAF), which can directly activate caspase 9, resulting in propagation of a direct signal ... action of particular pathways For example, the p210bcr-abl fusion protein tyrosine kinase drives chronic myeloid leukemia (CML), and HER-2/neu stimulates the proliferation of certain breast cancers ... combinations of drugs and targeted agents may maximize the chances of affecting critical pathways in the tumor Chemotherapeutic Agents Used for Cancer Treatment Table 81-2 lists commonly used cancer chemotherapy...

Ngày tải lên: 07/07/2014, 01:20

... qd cyclophosphamide x + of Bladder mesna More lipid Neurologic soluble Metabolic Greater acidosis activity vs testicular Neuropathy neoplasms and sarcomas Must use Liver and mesna Procarbazine ... mg/m2 IV Skin changes days and idine dehydrogenase deficiency increases toxicity Metabolizes in tissues Capecitabine 665 mg/m2 Diarrhea bid Prodrug 5FU due of to Hand-foot continuous; intratumoral ... syndrome 1250 mg/m metabolism bid weeks on/ off; 829 mg/m2 bid weeks on/ off + 60 mg/d leucovorin Cytosine arabinoside 100 mg/m2 Marrow per Enhances activity of alkylating Mucositis day qd x7 by continuous...

Ngày tải lên: 07/07/2014, 01:20