... University Avenue, Toronto, ON, Canada 2London Regional Cancer Program, 790 Commissioners Road East, London, ON, Canada Authors’ contributions BT synthesized the information from the meeting, and ... molecule-mediated inhibition of one molecule led to the activation of the other While inhibition of either STAT3 or Src via shRNA reduced EOC cell migration and invasion, inhibition of both Src and ... biologic rationale for targeting the pathway of interest, the genomic/proteomic profile of the tumour, the histological subtype, the molecular Page of activation of the target pathway, the type of...
Ngày tải lên: 20/06/2014, 07:20
... Firstly, one tries to find some new integral sum graphs (see [1, 3, 4]) Secondly, one tries to construct some new integral sum graph from the old ones (see [5]) Finally people concentrate on the investigation ... section, we give an affirmative answer to the above open problem, namely Theorem 2.1 If n is an odd number, then the cycle Cn is an -graph Proof At first we show that when the odd number n < 11, the ... (2) Therefore, Lemma 2.4 holds Up to now we obtain that the odd cycle Cn is an therefore Theorem 2.1 holds By Theorem 2.1, we obtain the following result Corollary 2.5 If Cn is an odd cycle then...
Ngày tải lên: 06/08/2014, 05:20
The Path To Excellence World Class Leadership
... buttons they have to press to get through to the person they are looking for or God forbid, how to talk to someone who can help when they don't know who they are looking for If you are going to ... meeting them in person In telephone situations, the voice and tone of the employee may be the most important part of the customer -supplier relationship The customer wants the supplier to have ... romance in the customer supplier relationship The customer wants to feel like they are the most important customer and that they have your full attention Demonstrating a commitment to the customer...
Ngày tải lên: 14/11/2012, 16:50
Tài liệu SOA Governance: The key to successful SOA adoption in your organization doc
... information could be safely ignored by the other application The First Milestone Soon afterwards, Spencer met with Jennifer, the project manager for the auto insurance application, to discuss their ... positioning them for consolidation which would save the company significant costs, in addition to allowing them to gain the visibility they needed to start selling other products to existing customers ... federal government The constituents of the organization are both the IT staff involved in the construction of services and their consumers, the business users that utilize the IT solutions, and in many...
Ngày tải lên: 18/02/2014, 09:20
EFFECTED FROM WOMEN ON THE BOARD TO BANK PERFORMANCE
... the descriptions of the theories used to explain the relationships between the two constructs Woman on the board and firm performance Agency theory and stewardship theory are used to define the ... also be one of the inside directors on the board (if not the chairman) * Chief Operations Officer (COO) – Responsible for the corporation's operations, the COO looks after issues related to marketing, ... go to the bank and demand your money, you'll get it However, if everyone goes to the bank at the same time and demands their money (a run on the bank), there might be problem Even though the...
Ngày tải lên: 07/03/2014, 15:43
The Path to Happiness and Wealth pptx
... problems are on the creditor safari They are on the hunt for the person or persons who got them into the situation they are in right now The honest answer is that you are probably the most to blame ... take in the country with the top down They needed to spend some quality time together Bob felt they were not as close as they used to be The car would help bring them closer together Because the ... get on the wheel and try to run in opposite directions That was interesting I tried to take the wheel out of the cage one night to stop the madness I think one of them sunk their teeth deep into...
Ngày tải lên: 22/03/2014, 23:20
The Sovereign Wealth Fund Initiative Summer 2012: On the Need to Rethink the Endowment Model…Again doc
... 5% to 20% A closer look also shows that following the financial crisis, the allocation to publicly traded stock declined, that to alternatives continued to rise, while the allocation to bonds ... “Investing for the Long Run”, in Bolton et al 21 Tett, “Singapore’s Lessons from the Harvard Model” 22 Spiegel defines long-term investors as a function of the liability structure of the fund: long-term ... not abandon the foundations of modern portfolio theory, but instead draws on and extends existing theory to inform the changing investment behavior of institutional investors under conditions of...
Ngày tải lên: 23/03/2014, 12:21
THE PATH TO PROSPERITY A BLUEPRINT FOR AMERICAN RENEWAL pdf
... weakened confidence in the nation’s institutions and its economy • Take action to eliminate wasteful Washington spending, building upon the suggestions of the President’s ... sector as elsewhere, the best way to control costs is to give Americans control over the money they spend on health services, thus letting bottom-‐up competition driven ... failed to use their full control of Washington to offer any plan to lift the debt and foster sustainable economic growth Instead, the crisis was used as an excuse to...
Ngày tải lên: 29/03/2014, 19:20
báo cáo hóa học: " Effects of the physiological parameters on the signal-to-noise ratio of single myoelectric channel" doc
... a contraction [18-20] Some modelling work on motoneuron firing patterns suggested that the range of the firing rate of the motoneuron during a steady contraction is to 50 pps [21] On the other ... Equation shows that the SNR at the ME channel output is insensitive to the amplitude of the MUAP but inversely related to the shape factor b The impact of the shape factor b on the morphology of the ... according to the target muscle when it is used to evaluate the ME control performance SNR related to the muscle contraction level Strongly related to the muscle contraction level, the recruitment...
Ngày tải lên: 19/06/2014, 10:20
The Path to Financial Freedom: A simple and easy guide to assist you in reducing or eliminating pdf
... in to years Let’s say you owe a total of $20,000 or more We will negotiate with your creditors to accept a 50% reduction The remaining debt will be paid back over to years at 0% interest The ... designed to assist consumers affected by the current economic climate This program will cover all steps to financial freedom: Reduce the negative flow of money Live within your budget Have your money ... comfortably handle) Enroll in a Creditor Approved Debt Modification Program The National Institute for Consumer Assistance (NICA) is designed to reduce principal liability The program works as follows:...
Ngày tải lên: 27/06/2014, 23:20
DNA REPAIR − ON THE PATHWAYS TO FIXING DNA DAMAGE AND ERRORS docx
... leads to topologic changes in the chromosomal regions that correspond to replication origins, facilitating the assembly/stability of the ORC hexamer Second, at the replication fork progression level, ... through the presence of a gap, such as the end of the Okazaki fragment, and the directional orientation of PCNA followed by the excision of the defective strand in the 5’ to 3’ direction by EXOI ... have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work Any republication, referencing or personal use of the...
Ngày tải lên: 28/06/2014, 05:20
Analyzing Big Data: The Path to Competitive Advantage
... planned to so In another study, The Deciding Factor: Big Data & Decision Making, conducted by the Economist Intelligence Unit for Capgemini, two-thirds of the executives note in the study that they ... that they consider their organizations to be “data-driven,” meaning that data collection and analysis are the foundation of their firms’ business strategies and day -to- day decision-making The percentages ... Big Data — The Path to Competitive Advantage Introduction Almost every business collects data, and the majority of it is about their customers Over the past several years the cost of storing data...
Ngày tải lên: 03/07/2014, 08:18
the key to successful branding
... thrее wеrе not іn the lеаdеrѕhір position today Leadership mеаnѕ long-term success, so ѕtrіvе tо bе on top www.faceonlineltd.co.uk Page 15 Chapter It’s not all about Quality www.faceonlineltd.co.uk ... іmрасt оn consumers whеn they hеаr thе wоrdѕ Bеѕt Buу Thіѕ gіvеѕ thе consumer the notion that thеу аrе going tо fіnd whаt they аrе looking fоr іn thе store аnd will be gеttіng іt fоr the best рrісе ... Barnes & Nоblе is the mоѕt successful brісk and mortar bооkѕtоrе, fаr outselling thеіr competition Yet, оn the Intеrnеt, it dоеѕ not еvеn соmе сlоѕе to thе same sales аѕ Amazon Amazon concentrated...
Ngày tải lên: 27/07/2014, 23:05
Báo cáo toán học: "On the distance to the set of compact perturbations of nilpotent operators " ppt
Ngày tải lên: 05/08/2014, 09:46
Báo cáo toán học: "On the path-avoidance vertex-coloring game" ppt
... extension of the construction in the previous section finally yields the lower bound on k ∗ (P , 2) claimed in Theorem the electronic journal of combinatorics 18 (2011), #P163 30 Proof of Theorem ... the electronic journal of combinatorics 18 (2011), #P163 Observe that if Builder confronts Painter several times with the decision on how to color a new vertex that connects in the same way to ... in color The precise strategy definition is given below in the proof of Proposition 12 The recursion defined in the following evaluates the performance of the strategy corresponding to the given...
Ngày tải lên: 08/08/2014, 14:23
Molecular approaches to malaria: on the way to integration Zbynek Bozdech ppsx
... that the stabilized regions are the main targets of protective antibodies synthesized by the host In addition, the ordered structural domains are mainly exposed to the surface and contain the ... associated with the telomeres and subtelomeric regions of the Plasmodium chromosomes, and probably extends into the var gene coding regions Although the detailed mechanism of the transcriptional switches ... coli along a given gene The plasmodial gene is then resynthesized in vitro, replacing every P falciparum codon synonymously with the equivalently used codon from E coli Using this technique the...
Ngày tải lên: 09/08/2014, 20:20
báo cáo khoa học: " On the road to diploidization? Homoeolog loss in independently formed populations of the allopolyploid Tragopogon miscellus (Asteraceae)" pptx
... progenitor, while the 'longliguled' form has T dubius as the maternal parent (Figure 1) Today, only one long-liguled population exists (in Washington Spokane The allopolyploids Tragopogon mirus ... follow the synthetic polyploids through successive generations to determine when homoeolog loss occurs and if this loss contributes to increased fertility One consistent pattern among the populations ... from the National Science Foundation (MCB0346437) to DS, PS, and JT and a grant from the Massey University Research Fund to JT We thank V Symonds and two anonymous reviewers for comments on the...
Ngày tải lên: 12/08/2014, 03:20
Báo cáo y học: "Patients'''' opinion on the barriers to diabetes control in areas of conflicts: The Iraqi example" docx
... migration in Basrah after the war, One type is migration from other governorates in Iraq to Basrah and another one is migration within the city The 3rd type is out side Iraq or to other parts of the ... control from these questions, and to choose more than one answer according to their wishes The answers were yes or no These questionnaires where suggested from the patients opinion for the cause ... questionnaire that was filled out by the medical staff of the clinic Overall, questions were present in the questionnaire Patients were asked to mention the main causes of poor glycemic control...
Ngày tải lên: 13/08/2014, 13:21
A study on the strategies to improve students reading skill
Ngày tải lên: 28/08/2014, 05:21
hubbard & navarro - seeds of destruction; why the path to economic ruin runs through washington, and how to reclaim american prosperity (2010)
... been wrong in the assumptions about a decade like the 1950s One is that strong unions can force the economy to grow by demanding high wages The only thing that made the high-wage policy of the 1950s ... go bust Once the housing bubble burst, the “house as an ATM” consumption stimulus for the economy went into reverse, and consumption spending slowed dramatically Today, as the American economy ... our lexicon When a television commentator tells viewers that consumer activity represents 70 percent of the economy—and the commentators that often the commentator is quantifying the economy using...
Ngày tải lên: 03/11/2014, 15:27