on ngf mutations and peptidomimetics in the treatment of alzheimers disease
The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease
... assembly It serves as a binding for the tubulin Mutations in α-synuclein lead to loss of this binding ability, resulting in tubulin and α-synuclein aggregation Properly functioning microtubules are ... are being developed targeting cerebral amyloid generation in AD They either inhibit the production of Aβ or escalate its clearance in the brain The most common mechanisms of action of these drugs ... neurotransmitter in the brain The interaction of glutamate with the N-methyl-D-aspartate (NMDA) receptor is important in the workings of memory and learning In AD an increase in glutamate activity results in...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... proopiomelanocortin and cocaine and amphetamine regulated transcript Taken together, these findings provide a compelling argument for the role for malonyl-CoA in regulating feeding behavior The question arises, ... cells containing mitochondria maintain some ability to beta-oxidize long-chain fatty acids, adult neurons not robustly oxidize long-chain fatty acids [40] The rate-setting step in long-chain fatty ... expressed in neurons so CPT1c and CPT1a largely not localize to the same cells in the brain, suggesting that they are functionally distinct Although Signaling mediators in the treatment of obesity...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... al roles in the control of energy metabolism, leading to body weight reduction Further investigations to clarify the each contribution of adipocyte and central effects on the regulation of energy ... expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased expression of RMI1 and E2Fs thereby ... deficiency in Skp2, the substrate-binding subunit of the SCFSkp2 complex, contributes to the degradation of p27Kip1, resulting in an induced resistance to obesity due to inhibition of preadipocyte...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... fluvoxamine monotherapy was effective in the treatment of psychotic major depression, and the switch to sertraline worsened the psychotic symptoms in the patient The mechanisms underlying the opposite ... for the treatment of psychotic major depression using SSRI monotherapy One possible mechanism may be due to the difference in the action of these SSRIs at the endoplasmic reticulum protein sigma-1 ... Page of 14 15 16 17 18 19 Competing interests The authors declare that they have no competing interests Authors' contributions AK, AT, JM and TK contributed to the clinical and rating evaluations...
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Báo cáo y học: " Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review" pdf
... design, in the collection, analysis, and interpretation of the data, in the writing of the manuscript, or in the decision to submit the manuscript for publication The contents are solely the responsibility ... of the healthcare system is not satisfactory There are limitations in the reimbursement of anti-HBV therapy, either in the selection of agent or the duration of dosing Therefore, lamivudine and ... telbivudine are more widely used in treatment of CHB In this systematic review, we focus on the comparison of the efficay of lamivudine and telbivudine in the Figure Effect of telbivudine vs lamivudine...
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Báo cáo y học: "Formulas Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study" docx
... stronger vasoconstrictive Page of (page number not for citation purposes) effect of the combination of the two drugs in comparison to epinephrine alone in the first minute of CPR with an increase ... demonstrated that the combination of epinephrine and vasopressin in the treatment of VF cardiac arrest improved perfusion pressures and short-term survival, in comparison to the single use of ... The combination of vasopressin and epinephrine resulted in a statistically significant elevation of both diastolic aortic pressure and CPP during CPR • The combination of vasopressin with epinephrine...
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WORMS: IDENTIFYING IMPACTS ON EDUCATION AND HEALTH IN THE PRESENCE OF TREATMENT EXTERNALITIES ppt
... is the treatment assignment of the school in 1998 (t = 1), and this takes on a value of one for Group and zero for Group schools The first term on the right-hand side of the equation (β1 ) is the ... medical treatment in 1998 This was partly because of confusion in the field about pupil age, and partly because in the early stages of the program several of the Kenya Ministry of Health nurses administered ... ESTIMATION STRATEGY 4.1 Econometric Specifications Randomization of deworming treatment across schools allows estimation of the overall effect of the program by comparing treatment and comparison schools,...
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báo cáo hóa học:" Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice" pot
... significant increase in the ovarian expression of caspase-3 and cleaved PARP proteins in mice Increase in the expression of caspase-3 and cleaved PARP proteins noticed in the mice treated in vivo ... effects of GnRH-Ag treatment on ovarian expression of ER-a and PR proteins (Figure 6) The effect of GnRH-Ag with and without LH on ovarian expression of ER-a and PR proteins in vitro are shown in ... effects of in vivo and in vitro treatment of GnRH agonist on morphological and physiological changes in the ovaries of intact cyclic mice Several in vivo and in vitro studies performed in rats...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case report in which lithium levels were maintained in the therapeutic range by intraperitoneal administration of lithium during continuous ... liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases metabolism of some anticoagulant ... baseline and again two weeks after beginning treatment If the patient gains four pounds or more, behavioral interventions of diet and exercise and a consultation with a nutritionist should be considered...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... arthritis or other types of pain) or is unwilling to stop taking other medications for the treatment of OA Any other condition that, in the opinion of the investigator, would adversely affect the subject's ... to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients Use of concomitant prohibited medication (narcotics, ... Combinations of glucosamine and chondroitin have been studied in the “GAIT” study These authors reported that glucosamine HCl and chondroitin sulphate alone or in combination did not reduce pain...
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Tài liệu The Benefits of Bank Deposit Rate Ceilings: New Evidence on Bank Rates and Risk in the 1920s (p. 2) docx
... second, more interesting page contains the examiner's remarks on the well-being of the bank This page contains information analogous to the more formal CAMEL rating the examiners construct today ... of confidence Turn to the examiner's report of condition in Appendix A On line 14 of its page appears the item "deposits withdrawable only on presentation of passbooks." The amount on this line ... F R B^htiD at the close of business on the I day of ^ ^ 192.9 as found upon exami- nation made by the direction and authority of the Superintendent Location of Banks of the State of New York H...
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báo cáo hóa học:" Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement" doc
... debris and synovitis, with no evidence of infection The bone graft incorporated fully by months and the right knee remains pain-free with good function and a 0-125 degree range of flexion years ... image of the left knee showing the introducing cannula and simultaneous venting of the medial tibial condylar cyst Discussion When dealing with massive periprosthetic osteolysis the aims of surgery ... radiograph of the knee demonstrating the area of calcium phosphate bone cementage in the medial femoral and medial tibial condyles grafting in 2000, following severe polyethylene delamination, osteolysis...
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báo cáo hóa học:" HIV-related restrictions on entry, residence and stay in the WHO European Region: a survey" ppt
... recently in conjunction with the 2009 outbreak of influenza virus A (H1N1) Together with international organizations, such as the International AIDS Society (IAS) [10], the International Organization ... free movement of people within the EU is one of its founding principles, a principle acknowledged not only in its founding and subsequent treaties, but also in the European Convention of Human Rights ... Parliament, Council of the European Union: Corrigendum to Directive 2004/38/EC of the European Parliament and of the Council of 29 April 2004 on the right of citizens of the Union and their family members...
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Báo cáo nghiên cứu khoa học: "STUDY ON THE APPLICATION OF MELALEUCA CAJUPUT ACTIVATED CARBON IN THE TREATMENT OF WASTE WATER FOR TEXTILE INDUSTRY" pps
... equilibrium constant,(1/ppm), q*(mg/g) and c*(ppm) are the concentrations of the adsorbate in the activated carbon and in the solution, that are in equilibrium with each other By logarithmizing the equation ... 3.3.Kinetics investigation Each volume of 1500 ml with determined initial concentration of dyestuffs is prepared for the kinetics investigations Two concentrations of the dyestuffs (20ppm and ... done to figure out the change of adsorbate concentrations in the solution The concentrations of the adsorbate in solid phase (activated carbon) are calculated on the base of material balances...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... Annals of General Psychiatry 2009, 8:16 the treatment of acute mania, the approval of quetiapine and the olanzapine-fluoxetine combination against acute bipolar depression and the approval of olanzapine, ... in all subpopulations irrespective of the baseline MADRS score and the presence of rapid cycling, with the exception of remission in patients over 55 years of age [107] Another metaanalysis of ... 87 h after ingestion) Complete resolution of symptoms and signs occurred after days There is also a single case report of induction of hyponatraemia [103] and another of aripiprazole-induced orthostatic...
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Báo cáo khoa học: "Factors of influence upon overall survival in the treatment of intracranial MPNSTs. Review of the literature and report of a case" doc
... advantages of both stereotactic radiotherapy and conventional fractionation while minimising the risks of RT-inducing brain injury like radiation necrosis and cognitive decline The optimal radiation ... background of these observations Conclusion In conclusion, we propose as therapeutic strategy for intracranial MPNST consisting of the maximal surgical resection feasible with preservation of neurological ... Authors’ contributions All of the authors have been involved in drafting this paper and have read and approved the final manuscript KG conceived the idea of the paper, reported the case, performed the...
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Báo cáo khoa học: "Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicitty" doc
... were contoured on a Pinnacle™ workstation version 8.0 (Philips Radiation Oncology Systems, Fitchburg, WI, USA) and defined according to the criteria of the International Commission of Radiation ... therapy Bethesda, MD: International Commission on Radiation Units and Measurements 1993 International Commission of Radiation Units and Measurements: ICRU Report 62: Prescribing, recording, and ... perform inverse treatment planning The planning goal was to deliver the prescription dose to at least 95% of the PTV The dose constraints for organs at risk (OARs) were mainly those reported in of the...
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Báo cáo khoa học: " Intensity modulated radiotherapy (IMRT) in the treatment of children and Adolescents - a single institution''''s experience and a review of the literature" pps
... responsible for the clinical treatment of the children as of the department of radiation oncology in the University of Heidelberg MM is responsible for the medical aspects of treatment planning and ... Krasin et al presented a planning study comparing different conventional photon, electron and IMRT techniques in the treatment of intraocular retinoblastoma [30] The best sparing of the bony ... is responsible for the anaesthesia management of the children PH is responsible for the clinical treatment of the children as head of the division of radiation oncology in the German Cancer Research...
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Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors" pptx
... J, Grandjean JP, Partensky C, Souquet JC, Adeleine P, Gerard JP: Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing ... survival (Table 3) These findings reflect the influence of tumor extension at the time of diagnosis, which can lead to distant dissemination, the main cause of death among our patients Other series ... surgery and did not develop local failure, the sphincter preservation rate among patients with initial indication of APR was of 26.8% (19/71) Postoperative staging and surgical findings The postoperative...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25