old as shown in body simulation

... (MPI) programming environments, and new developments in ‘grid computing’ Finally, it touches on the increasing importance of software packages in scienti¢c computing, and the increased importance ... of introducing good software engineering practices into very large academic software development projects 2002 In silico simulation of biological. .. Complexity in biological information ... can achieve integration along several intersecting axes (Fig 1): structural integration implies integration across 6 McCULLOCH & HUBER FIG 1 Three intersecting... Biomedical Engineering, University

Ngày tải lên: 11/04/2014, 09:47

... dance of which he was thinking was that described by Charles " dance in which every motion was a word, Kingsley and rest as eloquent as motion; in which every attitude A was a fresh motive ... endowed him, was called into play With this work German comic opera took its 23 24 Mozart " beginning As has been remarked although it has been imitated, it has never been surpassed in its musically ... Kerst passionately devoted to the sport obviously misconceiving Mozart' s words It is plain to me that the composer had the classic definition of the dance in mind when he... fugue was in

Ngày tải lên: 04/06/2014, 15:41

... said that he was no dancer The dance of which he was thinking was that described by Charles " dance in which every motion was a word, Kingsley and rest as eloquent as motion; in which every ... unnatural distortions, but in perpetual... fugue was in G minor) I began in the major, with something jocose but in the same tempo; finally the theme again, but backwards Finally I wondered if ... endowed him, was called into play With this work German comic opera took its 23 24 Mozart " beginning As has been remarked although it has been imitated, it has never been surpassed in its musically

Ngày tải lên: 04/06/2014, 15:41

... (11) In the above equation, d is defined as in (10). This optimiza- tion can be exhaustively solved, since the cardinality of M is small. As shown in Figure 4, m index can be transmitted as plain-text ... schemes as special cases, in ad- dition to other intermediate possibilities. 5. INTRAS DATA SCRAMBLING In the previous section, the general infrastructure and several approaches for generating and ... referred to as INTRAS, being effectively a combination of interpolation and random sampling, which is inspired by [20, 21]. The idea is to modify the signal after sampling, but before binary encoding.

Ngày tải lên: 22/06/2014, 00:20

... reproduction in any medium, provided the original work is properly cited. 1. INTRODUCTION The capacity of integrated circuits has increased significantly in the last decades, following a trend known as ... footprint, exceeding 50% in all cases. For almost all the tests, the 10% AR threshold yields a footprint less than 50%. The Ethernet code has larger activity footprints in general, but the footprint ... increases by at least afactoroften[2], with verification time taking at least 70% of the design cycle [3]. Compounding the problem are the large, nonrecurring expenses of producing or correcting

Ngày tải lên: 22/06/2014, 05:20

... taxa did not In both cases there were marked declines in Torresian taxa with increasing SO2 The intensive survey showed marked increases in Eyrean taxa with increas- ing SO2, but this was only weakly ... regionally dominant landforms (rocky ridges and alluvial plains) supported distinct ant faunas Ant abundance declined with increasing levels of SO Species richness declined with increasing levels ... variation was not quite statistically significant Only one species, Camponotus sp A (denticulatus gp), was commonly recorded in our study as well as in the intensive survey, and in both cases abundance

Ngày tải lên: 28/07/2014, 17:21

... antigens was measured in at least three tissue sections. The intensity of the staining was not taken into account as no obvi- ous differences were observed in staining intensities in the dif- ... cartilage was measured in sections stained with Safranin O and Fast Green using a computerized imaging system as previously described [25]. Briefly, Safranin O stains PGs in the cartilage red. A blinded ... This indicates a decrease in active TGF-beta signaling in old mice, possibly related to the decreased number of TGF-betaRs in old mice. To assess whether IL-1 itself altered TGF-beta signaling in

Ngày tải lên: 09/08/2014, 07:20

... selection intensity in female ducks (i = 1.271), constrained selection based on a phenotypic selection index or a genetic index could increase the expected genetic gains in ... at present are to maintain EW40 and BW40 at their current genetic levels, to increase as much as possible the genetic level in NEGG52, while getting a positive genetic ... selection index was constructed with conventional estimated genetic parameters (table I) to increase the number of eggs while holding egg weight and body weight constant in Brown

Ngày tải lên: 09/08/2014, 18:22

... carcinogenic products[1]. While the cancer incidence remains high in South and South East Asia (its traditional high risk areas); parts of Central and Eastern Europe are seeing alarming increase ... peroxidase, type I iodothyronine deiodinase, metal- loprotein, fatty acid binding protein and selenoprotein P. therefore selenium is considered as an antioxidant nutri- ent and the diseases where ... areca nut chewing and associated hab- its. The mean age was higher in the patients suffering from oral carcinoma. Gross et al [29] reported that ageing is associated with a decline in the cell

Ngày tải lên: 11/08/2014, 23:22

... investigate cytokines involved in joint inflammation during an acute response that may offer insight into early proinflammatory cytokine release in the initial... deWoody K, Feldmann M, Maini RN: ... rhIL-18 (2.5 nM) probing for phospho-ERK (n=4) * * *p < 0.05 1/2 1/2 1/2 p-p38 total p38 0 min 1min 5 min 15 min 30 min 45 min p-ERK½ total ERK½ 0 min 1min 5 min 15 min 30 min 45 min (n=5) * p < ... that IL-18 is critical in acute inflammation of murine joints in as early as 24 hours after zymosan injection (n = number of joints analyzed). 2 4 6 8 10 12 Inc. in hind joint circ. from day 0

Ngày tải lên: 12/08/2014, 14:22

... was recorded as a measure of airway hyperreactivity. Enzyme-linked immunosorbent assays (ELISAs) The levels of cytokine and chemokine proteins in whole lung homogenate were measured as previously ... 3C). In each case, increases in cytokines and chem- okines were blunted to a similar degree with PIO (P < 0.05) or DEX (P < 0.05) treatment. While CRA induced only a modest increase in expression ... (Fig. 4A). No positive staining for PAS was observed in control lung sections (data not shown). Goblet cell hyperplasia and mucin production are associated with increased tran- scription of the

Ngày tải lên: 12/08/2014, 15:21

... CIDE-A in elevation of circulating FFA Specifically, a decrease in CIDE-A expression results in increased TNF-α secretion resulting in increased lipolysis The increased basal WAT lipolysis induced ... tissue was isolated Mice fed standard chow served as control animals Type diabetic mice were characterized as having > 200 mg/dl fasting blood glucose and at least a 2-fold increase in fasting plasma ... due solely to increased age per se, but more likely a consequence of increased insulin resistance in the mice at older ages [30] Insulin resistance is a common occurrence in aging individuals and

Ngày tải lên: 13/08/2014, 13:20

... suffering or getting infected with HIV/AIDS, a sexually transmitted disease and/or an unwanted pregnancy. In this article, HRSB was taken to include engaging in one, some or all the following ... excluded from the final study Research assistants were trained on all aspects... tool was originally formulated in English but translated into Itesot, and blind back-translated into English to ... sub-themes in the dataset as we read the transcripts. We used illuminating verbatim quotations to illustrate major findings. Results The commonly identified HRSB behaviours include; transactional

Ngày tải lên: 13/08/2014, 15:21

... misfortune she has inflicted on him Seemingly, his love for her has been so deep and so long that caring for her has become his instinct, and feeling happy for her happiness has become an old habit ... imaginary, but from the reality. He spent his whole life experiencing the world relentlessly, broadening his mind and enriching his soul with fascinating stories of adventures, then collecting ... indeed keep his promise since Teresa was truly the last love in his short life Nevertheless, there was no happy ending for Byron’s love life, as the moment they said farewell in

Ngày tải lên: 18/09/2014, 15:57

... form-making or with problem-solving, but can view the experience of the build- ing as an integrated whole—. . . .” John Morris Dixon H EATING , C OOLING , AND L IGHTING AS F ORM -G IVERS IN A RCHITECTURE ... the heating, cooling, and lighting of buildings was the domain of architects. Thermal comfort and lighting were achieved with the design of the building and a few appliances. Heating was achieved ... 1.2e). 2 HEATING, COOLING, AND LIGHTING AS FORM-GIVERS IN ARCHITECTURE Figure 1.2a Massive construction, small windows, and light colors are typical in hot and dry climates, as in this Saudi

Ngày tải lên: 19/06/2015, 11:30

... DECISION MAKING IN SPORTS: AN INVESTIGATION OF 12- TO 19-YEAR-OLD BASKETBALL PLAYERS IN SINGAPORE NG YUWEN STELLA NATIONAL UNIVERSITY OF SINGAPORE 2014 DECISION MAKING IN SPORTS: AN INVESTIGATION ... making can be classified... is important as it allows the decision maker to learn and gain expertise in decision making skills As one gains more experience in decision making, ... research in decision making The study of decision making has been researched in many distinct yet interrelated disciplines (M... that most decision makers have a vested interest in

Ngày tải lên: 09/09/2015, 11:10

... protocol. Triamine unit 87 was easily obtained by treating N-tosyl aziridine 86 in MeOH saturated with NH3 gas in a sealed vessel. After removing the solvent and the residue was dissolved in MeCN and ... groups was conducted in liquid ammonia in the presence of sodium. After the final cyclization step, the triamine intermediate was cyclized to give the chiral bicyclic guanidine 25. It was basified ... of the amount of D2O on the asymmetric H/D exchange reaction was investigated. As shown in Figure 2.1, the enantioselectivities increased when the amount of D2O increased from 10 equivalents to

Ngày tải lên: 10/09/2015, 15:51

... 104. The key intermediate 105 was obtained by the reaction between 104 and 103 using pyridine as solvent. After the oxidation with Br2 in pyridine, the product 106 was obtained as yellow solid ... amination products (108b~108k) was 3.2.5 Proposed mechanism of asymmetric amination reation Recently, there was an increased attention for utilizing chiral guanidine molecular as Brønsted base ... reation Recently, there was an increased attention for utilizing chiral guanidine molecular as Brønsted base catalyst The guanidinium intermediate was formed by abstracting one proton from the

Ngày tải lên: 10/09/2015, 15:51

... a good catalyst for the asymmetric Mannich reaction of -fluorinated aromatic ketones. The effect of different protecting groups on imines was investigated in the preliminary study. The reaction ... -fluorinated aromatic ketone 82d Conversion was determined by TLC bdr and ee values were determined by chiral HPLC a In the preliminary study, N- ethyl maleimide 166a was used as Michael ... show any enantioselectivity in presence of pentanidine 163e although the best diastereoselectivity 1/9 was obtained. Table 4.2 Asymmetric Mannich reaction of various imines a Reaction time/h

Ngày tải lên: 10/09/2015, 15:51

... reported in parts per million (ppm). The residual solvent peak was used as an internal reference. Low resolution mass spectra were obtained on a Finnigan/MAT LCQ spectrometer in ESI mode and a Finnigan/MAT ... were determined by chiral HPLC analysis on two sets: Jasco HPLC units, including a Jasco DG-980-50 Degasser, a LG-980-02 Ternary Gradient Unit, a PU-980 Intelligient HPLC Pump, UV-975 Intelligient ... 4 min Modification of amination products To a 50 mL RBF containing 108h (107 mg,... nm; retention time: major isomer: 124.3 min; minor isomer: 132.8 min 5. 4 Protocol for bicyclic guanidine

Ngày tải lên: 10/09/2015, 15:51