objectives and functions of a cancer registry

MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1

MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1

... microRNAs and lung cancer: tumors and 22-mers Cancer Metastasis Rev 2010, 29:109–122 24 Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, ... study material and patients SM and DW performed the data analysis and interpretation LJ wrote the manuscript WZX approved the final version All authors read and approved the final manuscript Acknowledgements ... were harvested and assayed with Dual-Luciferase Reporter Assay kit (Promega, USA) according to the manufacturer’s instructions Western blot assay Statistical analysis Proteins were isolated and

Ngày tải lên: 05/11/2020, 07:45

11 30 0
Consequences of screening in cervical cancer: Development and dimensionality of a questionnaire

Consequences of screening in cervical cancer: Development and dimensionality of a questionnaire

... data (including statistical reports and tables) in the study and take responsibility for the integrity of the data and the accuracy of the data analysis JB is the guarantor All authors read and ... materials The datasets generated during and analysed during the current study are not publicly available due the Danish legislation of data protection but are available in an anonymously format ... survey data via a project manager JB and VS analysed the data JB drafted the manuscript and HT and VS contributed to revisions with important intellectual content All authors had full access to all

Ngày tải lên: 10/01/2020, 13:52

13 36 0
Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer

Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer

... characteristic aberrant glycosylation as a result of reduced activity of glycosyltransferases and accelerated activity of sialyltransferases in the MUC1 biosynthesis in breast cancer cells (12), breast-(TA)MUC1 ... The aim of the current study was to evaluate the mAb GGSK-1/30 as a diagnostic and prognostic tool for breast cancer Therefore, this mAb was evaluated by applying immune histochemical assays and ... human breast cancer specimens A collective of breast cancer tissue sections from 144 patients was examined for (TA)MUC1 specific staining Paraffin sections of healthy breast tissue (A) and paraffin

Ngày tải lên: 15/01/2020, 19:03

11 37 0
The value of miR-155 as a biomarker for the diagnosis and prognosis of lung cancer: A systematic review with meta-analysis

The value of miR-155 as a biomarker for the diagnosis and prognosis of lung cancer: A systematic review with meta-analysis

... 21 Zamora J, Abraira V, Muriel A, Khan K, Coomarasamy A Meta-DiSc: a software for meta-analysis of test accuracy data BMC Med Res Methodol 2006;6:31 22 Gao F, Chang J, Wang H, Zhang G Potential ... Foundation of China (no 81874230) in collecting and analyzing data Availability of data and materials The data that support the findings of this study are available from the corresponding author ... and design of this study SCC and YFM conducted the collection of materials and data management Analysis and interpretation of the data were performed by QZQ and YFM The writing and revision of

Ngày tải lên: 17/06/2020, 19:12

10 46 0
Mammographic density and risk of breast cancer by tumor characteristics: A casecontrol study

Mammographic density and risk of breast cancer by tumor characteristics: A casecontrol study

... was applied on each transformed mammographic measure, adjusting for age at mammogram, BMI (standardized according to the controls) and all the matching variables, and the residuals were standardized ... Melbourne Collaborative Cohort Study (MCCS) Page of 23 analysed before [6], to investigate if the association between DA, PDA and NDA and inherent risk of breast cancer, and the risk of masking vary by ... the association between BMI and risk to vary by age [7, 8, 10] and none of them had investigated the concurrent associations of dense area (DA), percent dense area (PDA) and non-dense area (NDA)

Ngày tải lên: 23/07/2020, 02:37

23 14 0
Repurposing existing medications as cancer therapy: Design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell

Repurposing existing medications as cancer therapy: Design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell

... Government Additional support was also received from the Laura Gralton Philanthropic Fund Availability of data and materials The datasets used and analyzed during the current study are available from ... participated in data analysis and interpretation NNS, MH, SC, BD collected and interpreted data All authors contributed to writing as well as read and approved the final manuscript Ethics approval and ... is a critical component of improving cancer care and outcomes This is particularly warranted for drugs that demonstrate anti-cancer efficacy in animal models [12–14] and are associated with improved

Ngày tải lên: 24/07/2020, 01:13

12 18 0
A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women

A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women

... various times of day, based on participants’ availability Laboratory analysis of PFR metabolites For each participant, a 5-ml aliquot was analyzed for PFR metabolites of the commonly used parent compounds ... F, Giovanoulis G, van Waes S, Padilla-Sanchez JA, Papadopoulou E, Magner J, et al Comprehensive study of human external exposure to organophosphate flame retardants via air, dust, and hand wipes: ... previous diagnosis of cancer (except for non-melanoma skin cancer) Tumor subtypes were histologically confirmed (papillary, follicular, medullary, and anaplastic) A total of 462 cases participated

Ngày tải lên: 24/07/2020, 01:31

10 24 0
New use of low-dose aspirin and risk of colorectal cancer by stage at diagnosis: A nested case–control study in UK general practice

New use of low-dose aspirin and risk of colorectal cancer by stage at diagnosis: A nested case–control study in UK general practice

... collection, analysis and interpretation of the data nor the interpretation of data or manuscript writing, except for in the form of salary paid to MS-G Availability of data and materials The datasets ... Coloproctology of Great Britain and Ireland/The Northern and Yorkshire Cancer Registry and Information Service/The NHS Information Centre for Health and Social Care The National Bowel Cancer Audit Annual ... Observational data suggest aspirin may reduce the risk of metastatic breast [5] and prostate [6] cancer at initial presentation, and reduced mortality has been reported for CRC [7] and breast cancer

Ngày tải lên: 06/08/2020, 03:47

11 35 0
Active smoking and risk of breast cancer in a Danish nurse cohort study

Active smoking and risk of breast cancer in a Danish nurse cohort study

... period was high, and based on data from a related Andersen et al BMC Cancer (2017) 17:556 Page of 11 Table Association between active smoking and breast cancer in 21,831 women in the Danish Nurse ... important intellectual content All authors read and approved the final manuscript Ethics approval and consent to participate The study was entirely based on register data and was approved by the Danish ... smoking and breast cancer risk among AfricanAmerican women Cancer Causes Control 2013;24:2207–15 Bjerkaas E, Parajuli R, Weiderpass E, Engeland A, Maskarinec G, Selmer R, et al Smoking duration

Ngày tải lên: 06/08/2020, 04:56

11 40 0
The feasibility and benefit of a brief psychosocial intervention in addition to early palliative care in patients with advanced cancer to reduce depressive symptoms: A pilot randomized

The feasibility and benefit of a brief psychosocial intervention in addition to early palliative care in patients with advanced cancer to reduce depressive symptoms: A pilot randomized

... Oliveira2, Maria Salete de Angelis Nascimento3 and Carlos Eduardo Paiva1,2,4,5* Abstract Background: The aim of this study was to assess the feasibility and potential benefit of a brief psychosocial ... intervention + early PC combined with standard cancer treatment; B (intervention) – early PC combined with standard cancer treatment; and C (control) – standard cancer treatment Randomization was performed ... Feasibility was investigated by calculating rates (%) of inclusion, attrition, and contamination (% of patients from Arm C that received PC) Scores of depression (primary aim), anxiety, and quality of

Ngày tải lên: 06/08/2020, 05:03

11 23 0
Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with nonsquamous non-small cell lung cancer in New Zealand

Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with nonsquamous non-small cell lung cancer in New Zealand

... University of Auckland, B507, 22-30 Park Ave, Grafton, Auckland 1072, New Zealand 2Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand 3Auckland Cancer Society Research ... University of Auckland, New Zealand Mark James McKeage, Professor - Medical, Pharmacology and Clinical Pharmacology | Auckland Cancer Society Research Centre, University of Auckland, New Zealand Prashannata ... data collection, data analysis, or preparation of the manuscript for publication Availability of data and materials The data that support the findings of this study are available from New Zealand

Ngày tải lên: 06/08/2020, 05:46

12 27 0
Role of geriatric intervention in the treatment of older patients with cancer: Rationale and design of a phase III multicenter trial

Role of geriatric intervention in the treatment of older patients with cancer: Rationale and design of a phase III multicenter trial

... principal investigator (oncologist), a coordinating geriatrician, a pharmacist in charge of the pharmacovigilance, a biostatistician, a data manager and the coordinating clinical research assistant ... total study duration of years Statistical methods Randomization Statistical analyses For the phase III trial, randomization will be performed on an individual basis based on a 1:1 allocation ratio ... uniscale and linear analogue self-assessment (LASA) at baseline and weeks 4, 8, and 27 - Significant improvement in QoL (p < 0.05) at baseline, maintained at and weeks Rao [14] Subset analysis

Ngày tải lên: 20/09/2020, 18:44

11 21 0
Establishment and characterization of a metastasis model of human gastric cancer in nude mice

Establishment and characterization of a metastasis model of human gastric cancer in nude mice

... Huifen Du1, Xiaowen Lian1, Dandan Chai1, Xinwen Li2, Rong Yang3 and Chunya Wang1 Abstract Background: A mouse model of metastasis of human gastric cancer is one of the most important tools for ... biological mechanisms underlying human gastric cancer metastasis In this paper, we established a mouse model of metastatic human gastric cancer in nude mice that has a higher rate of tumor formation ... retroperitoneum and viscera The implanted and metastatic tumor maintained the same histological features across all generations, and metastasis was observed in the esophagus, stomach, spleen, liver,

Ngày tải lên: 21/09/2020, 11:27

10 12 0
Cannabis exposure and risk of testicular cancer: A systematic review and metaanalysis

Cannabis exposure and risk of testicular cancer: A systematic review and metaanalysis

... statistical analysis and interpretation of data, and provided critical revision of drafts JS assisted with conception and design, assisted with statistical analysis and interpretation of data, ... screened abstracts, and also checked meta-data extracted by JG against the included manuscripts DS assisted with conception and design, assisted with statistical analysis and interpretation of data, ... doi:10.1093/ije/dym018 15 Alam SS, Cantwell MM, Cardwell CR, Cook MB, Murray LJ Maternal body mass index and risk of testicular cancer in male offspring: a systematic review and meta-analysis Cancer Epidemiol

Ngày tải lên: 22/09/2020, 22:43

10 19 0
Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: A census-based cohort study

Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: A census-based cohort study

... Australia, Perth, Western Australia, Australia 3Division of Paediatric Haematology and Oncology, Department of Paediatrics, Inselspital, University of Bern, Bern, Switzerland 4Pediatric Haematology-Oncology ... Epidemiology and Registration (www.nicer.org) Availability of data and materials The datasets generated and/or analysed during the current study are not publicly available due to local data protection policies ... of an association between paternal exposure around conception and acute lymphoblastic leukaemia (ALL) [16] For CNST, a review and meta-analysis of 20 studies suggested a positive Page of 11 association

Ngày tải lên: 22/09/2020, 23:18

11 10 0
Knowledge and experience of a cohort of HIV-positive and HIV-negative Ghanaian women after undergoing human papillomavirus and cervical cancer screening

Knowledge and experience of a cohort of HIV-positive and HIV-negative Ghanaian women after undergoing human papillomavirus and cervical cancer screening

... women after undergoing human papillomavirus and cervical cancer screening Arabella Stuart1,2, Dorcas Obiri-Yeboah3* , Yaw Adu-Sarkodie4, Anna Hayfron-Benjamin5, Angela D Akorsu6 and Philippe Mayaud2 ... education on cervical cancer amongst market women in an urban area of Lagos, Nigeria Asian Pac J Cancer Prev 2010;11(1):137–40 20 Adanu RM Cervical cancer knowledge and screening in Accra, Ghana ... assistants Ann-Marie Cudjoe and Amanda Odoi, and to the Cape-Coast Teaching Hospital clinic nurses who administered the questionnaires Ethics approval and consent to particiapate All participants gave

Ngày tải lên: 23/09/2020, 11:53

11 18 0
Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

... primers (forward, 5¢-TAATACGACTCACTATAGGTACTATG TATCGCATGCCAAT-3¢; reverse, 5¢-TAATACGACTC ACTATAGGTACTTTAAAGTCCCGGGTTGA-3¢) For PCR, the reaction mix consisted of · Taq buffer containing 1.5 mm ... culture tanks At 24, 48 and 72 h after injection, the hepatopancreas and ovary of the shrimp were dissected for total RNA preparation, and the hemolymph samples were collected for SDS ⁄ PAGE and western ... Functional study of crustacean neuropeptide S H.-K Tiu and S.-M Chan in the stimulation of gonad maturation Injection of protein extract from thoracic ganglion or the brain can stimulate gonad maturation...

Ngày tải lên: 16/03/2014, 05:20

11 546 0
báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx

báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx

... Immunostaining of prostate cancer tissue with antibodies against AMACR and PSA Immunostaining of prostate cancer tissue with antibodies against AMACR and PSA Surgically resected prostate cancer ... expression of β-actin mRNA and AMACR mRNA in prostate cancer line LNCaP, but only very weak expression of AMACR mRNA was observed in normal adult liver and pancreas (Figure 1A) In contrast, the AMACR ... De Marzo AM, Isaacs WB: Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer Cancer Res 2003, 63:7365-7376 Date Y, Kimura A, Kato H, Sasazuki T: DNA typing...

Ngày tải lên: 18/06/2014, 15:20

11 531 0
báo cáo hóa học: " Reliability and validity of a new scale on internal coherence (ICS) of cancer patients" pot

báo cáo hóa học: " Reliability and validity of a new scale on internal coherence (ICS) of cancer patients" pot

... Leiomyosarcoma Melanoma Ovarian carcinoma Ovarian sarcoma Pancreatic cancer Pharyngeal cancer Plasmocytoma Pleural mesotelioma Prostatic cancer Rectum carcinoma Thymic carcinoma Thyroid carcinoma Tonsillar ... Puhlemann and Lisa Arndt for recruitment of participants and Dagmar Brauer for the database documentation and lecture MK, RZ, DB Page 10 of 11 (page number not for citation purposes) Health and Quality ... functioning, and a significant increase of physical and role functioning and global health (table 7) The above mentioned results point towards a relevant correlation with quality of life and a scale sensitive...

Ngày tải lên: 18/06/2014, 18:20

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báo cáo hóa học: " Cancer risk among residents of Rhineland-Palatinate winegrowing communities: a cancer-registry based ecological study" pot

báo cáo hóa học: " Cancer risk among residents of Rhineland-Palatinate winegrowing communities: a cancer-registry based ecological study" pot

... Characteristics of the Rhineland-Palatinate vineyard area Rhineland-Palatinate* Total Communities Total area (ha) Area under wine (ha) % area under wine Inhabitants (per ha) Inhabitants per community (median, ... figures and data on area under wine cultivation were obtained from the statistical office of Rhineland-Palatinate Statistical methods Completeness of the Rhineland-Palatinate cancer registry varies ... (C20) Anus and anal canal (C21) Liver and intrahepatic bile ducts (C22) Gallbladder & biliary tract (C23–C24) Gallbladder (C23) Other and unspecified parts of biliary tract (C24) Pancreas (C25) Nasal...

Ngày tải lên: 20/06/2014, 00:20

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