objectification of renal tumor anatomy

... evidence of recurrence (Figure 4) Discussion According to the literature, the synchronous presentation of renal tumors of diverse histology and dignity is a rare phenomenon [1,2] The majority of published ... we decided not to proceed with genetic analysis of the specimen Oncocytomas are the most common benign renal tumors (3% to 7% of all solid renal tumors) [8] They are usually diagnosed incidentally ... sporadic coexistence of three different types of renal tumor A similar case with the concurrent occurrence of three primary neoplasms in the same kidney - oncocytoma, chromophobe renal cell carcinoma...

Ngày tải lên: 11/08/2014, 17:21

... hormone Granulosa cell tumors Granulosa cells of ovarian follicles (member of the transforming growth factor-b family) Sertoli cells of male fetus, 140 kDa for regression of Müllerian ducts Cell ... SCC is an oncofetal antigen [39] The analysis of in vitro culture of amnion cells and amniotic membranes revealed no accumulation of SCC in the supernatant, and no mRNA expression of SCC was found ... reliable during pregnancy than inhibin B Page of 10 Risk of bias We aimed to minimize risk of bias of individual studies by excluding all studies reporting tumor markers measured in pregnancies with...

Ngày tải lên: 13/02/2014, 06:20

... conformation of ETNF-6 mAb Sequencing of the cDNA of the variable region of ETNF-6 mAb was performed, and this was followed by molecular modeling of its three-dimensional structure The heavy chain of ETNF-6 ... chromatograms After a reaction time of 47.2 h, the amount of TP41-1 at a retention time of 11 decreased, because of fragmentation The fragment was observed at a retention time of 13 (indicated by an arrow) ... injection of 50 lg per mouse of the emulsion in Freund’s incomplete adjuvant (Difco Laboratories) at 2-week intervals after the first immunization A final dose of 50 lg of human hTNF-a in 100 lL of NaCl...

Ngày tải lên: 06/03/2014, 22:21

... 32 Renal Tumor Signaling pathways in renal tumors Renal tumors originates from the tubular structures of the kidney and is calssified into four major histological cell types Clear-cell renal tumor ... may reveal a new mechanism of regulation of cytokinesis and tumor suppression Genetics of Renal Tumors http://dx.doi.org/10.5772/54588 3.3 Kank-family genes and renal tumors The Kank1 gene was ... Associated with Renal Cell Carcinoma 109 Akihiro Tojo VI Contents Section Management of Metastatic/Advanced Renal Tumor 131 Chapter Surgical and Oncological Results of Treatment of Metastases of Renal...

Ngày tải lên: 23/03/2014, 14:20

... mechanism of Zn2+- and Ca2+dependent activation of S100 proteins The antagonistic effect of Zn2+ and Ca2+ in the control of S100A2 stability provides a molecular rationale for the action of both ... S100A2-DCys have very similar T app values of 58.4 and 59.5 °C, respectively, which are m lower than the T app value of 66.6 °C of S100A2-C2S m The outlying behaviour of apo S100A2-C2S may result from ... presumably a result of the general destabilization of the protein Further contributions might come from the exposure of a hydrophobic surface on Zn2+ binding [12], making additional exposure of the hydrophobic...

Ngày tải lên: 30/03/2014, 02:20

... deviation of the measurements Fig Dependence of the release rate of calcein from liposomes on the amount of TRAIL at pH 4.5 Various amounts of TRAIL were added to liposomes consisting of Myr2Gro-PCho ... intensity of calcein was determined to assess the amount of calcein in the liposome RESULTS Structural analyses of TRAIL by CD spectroscopy The effects of acidification on the contents of secondary ... with a significant change of tertiary structure Meanwhile, the effect of zinc ions on the conformation of TRAIL at acidic pH was investigated by analyzing the CD spectra of TRAIL, as zinc ions were...

Ngày tải lên: 31/03/2014, 08:20

... Atlas of Human Skeletal Anatomy Atlas of Human Skeletal Anatomy, eBook copyright 2002 by Juraj Artner, any work manipulation is strictly prohibited www.jurajartner.com Atlas of Human Skeletal Anatomy ... Atlas Atlas of Human Skeletal Anatomy Image - Anatomic directions, localizations and views www.jurajartner.com Atlas of Human Skeletal Anatomy Image - Basic anatomic structures of human body ... human body www.jurajartner.com Atlas of Human Skeletal Anatomy Image - Basic anatomic structures of human body www.jurajartner.com Atlas of Human Skeletal Anatomy Image - Basic bone histology...

Ngày tải lên: 08/04/2014, 12:35

... Institutional Review Board of the University of Pennsylvania Tumor inoculation For intraperitoneal (i.p.) tumors, ID8-Vegf cells were injected at × 106 per mouse For subcutaneous (s.c.) tumors, a single ... control tumors reached the size of ~800 mm3, animals were sacrificed, and tumors excised and weighed In Vivo Treatment Mice were treated with i.p bolus injections of Doxil in the range of 17% ... amalgamation of IL-18 mediated immune activation, with Doxil-mediated tumoricidal activity and increased immunogenicity of the surviving tumor cell fraction in vivo Although upregulation of MHC class...

Ngày tải lên: 18/06/2014, 15:20

... use of tumor target antigens like WT1 which are crucial for tumor cell proliferation However, further studies, especially on mechanisms of immune evasion at the effector phase of the anti -tumor ... loss of the HLA-A2 allele, we analyzed HLA-A2 expression on leukemic blasts of patients In all patients more than 90% of blasts stained positive for HLA-A2 In none of the patients a difference of ... acquisition of data, analysis and interpretation of data and wrote the manuscript; AL, AN and OS have made substantial contributions to acquisition of data, analysis and interpretation of data CS...

Ngày tải lên: 18/06/2014, 16:20

... mentioned above are based on the expression of surface markers on CTCs, in particular, EpCAM Table Comparison of EpCAM and cytokeratin (CK) expression profile of tumor cells in body fluids and peripheral ... correlation between presence of CTCs and lymph node status, and occurrence of synchronous metastases in a cohort of patients affected with renal cell carcinoma [30] Page of We detected CTCs after ... generation of cells with properties of stem cells, and to the ability of tumor cells to enter the circulation and seed metastases EpCAM-CK double positive CTC might represent only a subpopulation of...

Ngày tải lên: 18/06/2014, 19:20

... failure of anti -tumor immunity [1] Given the multitude of immune modulatory factors produced by tumors, it is indeed quite likely that different subsets of MDSC may be generated in the tumor microenvironment ... dependent upon the unique profile of factors secreted by the tumor [16,17,20] Preclinical models of human tumor- induced MDSC will significantly advance knowledge of their induction and function ... subsets of MDSC have been identified that will help elucidate the role of these cells in the ontogeny, spread, and treatment of cancer Page of 20 Methods Cell Lines and Cell Culture Tumor cell...

Ngày tải lên: 18/06/2014, 19:20

... mentioned above are based on the expression of surface markers on CTCs, in particular, EpCAM Table Comparison of EpCAM and cytokeratin (CK) expression profile of tumor cells in body fluids and peripheral ... correlation between presence of CTCs and lymph node status, and occurrence of synchronous metastases in a cohort of patients affected with renal cell carcinoma [30] Page of We detected CTCs after ... generation of cells with properties of stem cells, and to the ability of tumor cells to enter the circulation and seed metastases EpCAM-CK double positive CTC might represent only a subpopulation of...

Ngày tải lên: 20/06/2014, 03:20

... weight of MUC16 requires the use of extensive molecular biological approaches to study the importance of this mucin in the pathogenesis of ovarian cancer In addition, a thorough study of MUC16 ... Specificity of 618F for human MUC16 Specificity of 618F for human MUC16 (A) Purity of human MUC16 isolated from spent media of OVCAR-3 cells as determined by Coomassie Blue (1) and silver staining (2) of ... and probed with a panel of anti-MUC16 monoclonal antibodies Arrows indicate migration of 250 kDa molecular weight marker and identity of antibody used is shown on the right of each blot We have...

Ngày tải lên: 20/06/2014, 07:20

... from tumor cells [23] Fourier transform infrared spectroscopy has Page of been extensively employed in the field of cancer research to address the problems of tumor biology [24-30] The results of ... depletion of protein profile in the spectrum of malignant ovarian tissue indicates towards induced diversification of energy to meet the impending energy demands during the malignant stress of cell ... with the findings of Yamada et al where the analysis of secondary structure of proteins reveal increased amount of beta sheet in necrotic area of carcinoma as compared to alpha helix [24] Moreover...

Ngày tải lên: 20/06/2014, 07:20

... purpose of registering renal perfusion images This gives an idea of the effectiveness of different saliency methods Third, we use a randomized optimization scheme which evaluates greater number of candidate ... present proof of the suitability of saliency for registering contrast enhanced images Then we show properties of the different similarity measures with respect to registration These sets of results ... pixel windows from images of different stages of contrast enhancement In Figure 2, we show the mean saliency value of patches of sizes × 3, × 5, and × from different areas of the kidney, with best...

Ngày tải lên: 21/06/2014, 16:20

... 10 10 11 Adenoma Benign mixed tumor Benign mixed tumor Benign mixed tumor Benign mixed tumor Benign mixed tumor Benign mixed tumor Benign mixed tumor Benign mixed tumor Adenoma Adenocarcinoma ... Adenocarcnioma Malignant mixed tumor Adenocarcnioma] Malignant mixed tumor Adenocarcnioma Malignant mixed tumor Malignant mixed tumor Malignant mixed tumor Su rv ial(m o n th )* Typ e of d e a th ** P53 ... diagnosis and treatment of primary mammary tumors were included in this study The main clinicopathological parameters of the tumors are presented in Table The mean age of the dogs was 9.1±1.52...

Ngày tải lên: 07/08/2014, 15:20

... the RI, a renal interlobar or arcuate artery was Fig Determination of renal length and height on the transverse plane When the "C"-sign of the renal crest was clearly visible, the renal length ... and the dimensions of the renal medulla were not able to be clearly defined due to the unclear borders of renal sinuses in the transverse plane, the clinical application of renal cortical and ... weight has been observed in the renal dimensions (renal length, height, and width) and the renal cortical thickness, a low degree of correlation has been observed in the renal medullary thickness and...

Ngày tải lên: 07/08/2014, 23:22

... amplified in 90% of the presently studied tumors We identified 46 regions of gain present in more than 30% of the primary tumor samples and 70 regions of gain present in more than 30% of blood samples ... that of copy number gains There were 11 regions of loss found in more than 13% of the primary tumors and 16 regions of loss found in more than 13% of blood (Tables and 4) Thirty other regions of ... in at least 30% of both primary tumors and blood (Table 5) Among these, seven regions of copy number gain were found in more than 50% of both primary tumors and blood A gain of 5p15.33 was evident...

Ngày tải lên: 09/08/2014, 03:21

... the depth of penetration of tumors ranged from to cm (median 1,9 cm), without a direct contact with the upper excretory urinary tract (renal pelvis) in each of the patients enrolled The tumor diameter ... crucial to get a better understanding of the genesis of those reactions Ahead of its time are, on one hand, the recently applications of HAs in the premature rupture of membranes where the adhesive ... which compare the use of a HA and of the ISC in the enucleoresection of RCC The recent evidence related to the NSS capable, in selected cases, to offer the same results of partial and radical...

Ngày tải lên: 09/08/2014, 03:21