... Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) Good Clinical Practice (GCP), Guidelines of Taiwan and in accordance with the Declaration of Helsinki ... intervention, organic, neurological, cardiovascular diseases, or if they had a history of drug or alcohol abuse within the last 12 weeks Other exclusion criteria were pregnant or breastfeeding women, or ... compliant Of the 153 patients enrolled in the study, 106 patients (69.2%) were compliant with treatment Concomitant treatment with lorazepam and /or diphenhydramine was permitted during switching for...
Ngày tải lên: 09/08/2014, 01:21
... reviews of RCTs, or RCTs with a low risk of bias - Meta-analyses, systematic reviews of RCTs, or RCTs with a high risk of bias ++ High quality systematic reviews of case control or cohort studies ... for patients through the use of validation therapy include: 90 restoration of self worth minimisation of the degree to which patients withdraw from the outside world promotion of ... permission of Prof John R Hodges, MRC Cognition and Brain Sciences Unit, Cambridge 42 ANNEXES 43 MANAGEMENT of patients with dementia 44 ANNEXES 45 MANAGEMENT of patients with dementia 46 ANNEXES 47 MANAGEMENT...
Ngày tải lên: 08/03/2014, 14:20
The management of patients with venous leg ulcers: Audit Protocol ppt
... 1994; Moffatt et al 1994; Simon et al 1994) Strength of evidence IAssessment of Patients with Leg Ulcers The management of patients with venous leg ulcers Assessment 2.1 Assessment of Patients with ... sending it 24 The management of patients with venous leg ulcers Appendix 2: Audit Form The management of patients with venous leg ulcers Notes 25 26 The management of patients with venous leg ulcers ... reasons for falling short of this level on some occasions in relation to some criteria 20 The management of patients with venous leg ulcers Appendix 1: Audit Form Appendix Nursing Management of Venous...
Ngày tải lên: 15/03/2014, 23:20
Early management of patients with a head injury docx
... predictor of an abnormal scan with an OR of 3.52 2++ The OR for an abnormal CT is 4.1 in patients over 65 years of age.47 2++ The NEXUS II study of 13,728 patients found a CT abnormalities rate of ... included patients over 65 years of age.45,46 1++ 2+ 13 Early management of patients with a head injury Mechanism of injury was associated with intracranial injury, with ORs of 1.65 and 2.8 reported.39,47 ... half of those attending are children under the age of 14 years The majority of patients are fully conscious (see Table 1), without a history of loss of consciousness or amnesia or other signs of...
Ngày tải lên: 17/03/2014, 15:20
Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning pot
... SIGN 119 Management of patients with stroke: identification and management of dysphagia6 and SIGN 108 Management of patients with stroke or TIA: assessment, investigation, immediate management ... and liaised with services with the aim of improving aspects of participation and quality of life for patients with stroke and /or their carers The backgrounds of the stroke liaison workers varied ... support this role for all groups of patients and carers.16 10 1++ ORGANISATION OF SERVICES Typically the stroke liaison workers provided emotional and social support and information to stroke patients...
Ngày tải lên: 17/03/2014, 15:20
Management of patients with lung cancer docx
... for patients with NSCLC A A Patients with thoracic symptoms and poor performance status not suitable for radical radiotherapy should receive palliative radiotherapy with regimens of 10Gy/1F or ... supporting the use of blood tests, eg tumour markers, in the diagnosis of lung cancer Sometimes in patients of poor performance status (see annex 3) with major comorbidity, it is neither safe nor ... 54-80% for patients with stage 1A lung cancer and 38-65% for patients with stage 1B lung cancer Surgery gives the highest chance of cure for patients with stage I and II lung cancer D 6.2.2 Patients...
Ngày tải lên: 28/03/2014, 23:20
Báo cáo y học: "Efficacy of lifestyle interventions in physical health management of patients with severe mental illness" doc
... common cause of death in patients with SMI [2,29-32], and the statement proposes a series of interventions for the recommended management of CVD risk factors Several of these risk factors are modifiable, ... inter-relations of these CVD risk factors in patients with SMI were also evaluated, along with current Page of 10 evidence on how improvements in the management of the CVD risk factors may impact SMI patients ... Increased risk of hypertension in patients with bipolar disorder and patients with anxiety compared to background population and patients with schizophrenia J Affect Disord 2006, 95:13-17 47 Osborn DP,...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo khoa học: "Outcomes of resection and non-resection strategies in management of patients with advanced colorectal cancer" doc
... strategies should be offered as part of the process of informed consent, for patients with stage IV colorectal cancer, as survival is comparable to that of resection and without the burden of a stoma Further ... (bleeding, perforation or obstruction), and fitness for surgery Those patients who were unfit for any active intervention or who presented with terminal disease were managed with supportive care ... number of cases, median age and survival for each modality The operative mortality for non-resection surgery, stoma formation or bypass, was 36% (5/14) Of the 52 patients initially treated without...
Ngày tải lên: 09/08/2014, 04:21
Báo cáo y học: " Pro/con clinical debate: The use of prone positioning in the management of patients with acute respiratory distress syndrome" potx
... ill subset of patients with acute respiratory distress syndrome Those in the quartile with the highest Simplified Acute Physiology Score II (SAPS II) have a marked mortality benefit with ‘proning’ ... Effect of prone positioning on the survival of patients with acute respiratory failure N Engl J Med 2001, 345:568-573 The ARDS Network: Ventilation with lower tidal volumes as compared with traditional ... in the management of ARDS patients Gordon Rubenfeld Imagine the following scenario A novel treatment for a critical illness syndrome is reported in a case series [11,12] Animal models support a...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Pro/con clinical debate: Are steroids useful in the management of patients with septic shock" ppt
... elevated basal cortisol level (≥ 34 µg/dl) and a poor response to corticotropin (e.g ≤ µg/dl elevation at 30 or 60 min) to be a predictor of the poorest survival in patients with sepsis [3] It ... because of poor experiences with identical drugs given in higher doses [18] Levels of cortisol and responsiveness to ACTH stimulation in patients with sepsis vary considerably [19–21] A normal corticotropin ... refractory hypotension [5] Downregulation of catecholamine receptors occurs with prolonged use of exogenous catecholamines and this may be reversed with administration of low-dose steroids [6] Restoring...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis" ppt
... number of infections, reduces sepsis and reduces mortality related to acute pancreatitis Con: No, antibiotics are not important in the management of patients with pancreatitis with evidence of pancreatic ... increase in mortality (64%) compared with those patients without Candida (19%, P < 0.01) Certainly, critically ill patients developing superinfections tend to be those with more severe disease, with ... [4] Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with prophylactic antibiotics and 88 patients without [5]...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo khoa học: " Pulse pressure variation: beyond the fluid management of patients with shock" pot
... before performing recruitment maneuvers or before applying positive end-expiratory pressure in patients with acute respiratory distress syndrome, in order to prevent any hemodynamic deterioration ... respiratory distress syndrome still die of multiple organ failure and not of hypoxemia In this regard, PPV is now used (and normalized by the use of fluid) routinely by renowned groups [9] before ... contractility? Determinants of pulse pressure variation Pulse pressure variation (PPV) is a marker of the position on the Frank–Starling curve, not an indicator of blood volume or a marker of cardiac preload...
Ngày tải lên: 13/08/2014, 03:21
Management of neonates with suspected or proven early onset
... tenderness and /or foul odor of the amniotic fluid Pathogenesis and Epidemiology • The major risk factors for chorioamnionitis: low parity spontaneous labor longer length of labor and membrane ... sepsis is a major cause of morbidity and mortality • Diagnostic tests for early-onset sepsis (other than blood or CSF cultures) are useful for identifying infants with a low probability of sepsis ... third-generation cephalosporins risk factor for invasive candidiasis Treatment of infants with suspected early-onset • Bacteremia without an identifiable focus of infection is generally treated for 10 days...
Ngày tải lên: 14/11/2016, 06:35
Báo cáo y học: " Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study" potx
... rheumatoid cachexia (that is, involuntary loss of fat-free mass [FFM] with a proportional increase of body fat [BF]) in the presence of stable body weight [3,4] Body composition changes, particularly ... evaluation of the variables using a Kolmogorov-Smirnov test of normality revealed that none of them required transformation to reach normality Mean ± standard deviation was calculated for all variables ... these patients Given the RA-related alterations in body composition and the comorbidity associated with them, the examination of potential contributors to muscle wasting, such as smoking, is important...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management" pptx
... compared with healthy controls (❍) and with OA patients with a low pain score (VAS score of less than or equal to 40; ∇) No significant differences were observed between healthy controls and OA patients ... and all patients gave written informed consent All OA patients fulfilled the criteria of the American College of Rheumatology for the classification of OA [24] Isolation and culture of synovial ... relief, a reduction of the expression level of DREAM was shown in PBMCs from OA patients with a VAS score of greater than 40 (Figure 2) Less DREAM mRNA was detected in the group of patients suffering...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... should be reserved for those patients with a BMI of 30 kg/m2 or greater, or a BMI of 27 kg/m2 or greater and risk factors for weight related medical illnesses [12] Agents associated with weight loss ... review of effective pharmacotherapies is beyond the scope of this paper which will perform a selective review the psychotropic medications often prescribed to patients with bipolar disorder, with ... caring for these patients on a regular basis Therefore, psychiatrists must have a high index of suspicion for medical illness, as well as a basic knowledge of the risks associated with the use of...
Ngày tải lên: 25/10/2012, 10:51
Guidelines for the Nutritional Management of Children With Renal Disease pot
... if taken with meals, feeds or snacks Nutrition in Renal Disease Author: Kerry Walker Date of Review: March 2013 Version: 1.2 Authorised by: Dr TJ Beattie Q-Pulse Ref: YOR-DIET-001 Page of 10 Issue ... preferred choice for infants but if complications occur with PD, then haemodialysis may be necessary In patients with multi-organ failure, haemofiltration is used Protein kcal/kg/ideal body weight ... This guideline has been developed for dietitians and medical staff to assist in the nutritional management of infants and children with renal disease within Yorkhill Division Specifically these...
Ngày tải lên: 05/03/2014, 12:20
Báo cáo khoa học: Enzymes that hydrolyze adenine nucleotides of patients with hypercholesterolemia and inflammatory processes potx
... addition of ATP or ADP as substrate at a final concentration of 1.0 mm The reaction was stopped by the addition of 200 lL of 10% trichloroacetic acid to provide a final concentration of 5% The inorganic ... modifications of the method of Jentzsch et al [34] Briefly, 0.2 mL of serum was added to the reaction mixture containing mL of 1% orthophosphoric acid, and 0.25 mL of an alkaline solution of thiobarbituric ... the rate of platelet nucleotide hydrolysis Platelets comprise one of the components of the thrombus microenvironment and of the process of thromboregulation It is known that the rate of platelet...
Ngày tải lên: 16/03/2014, 10:20
Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis pptx
... controls Five TU of PPD - RT23 with Tween 80 was performed into1/3 upper lateral region of the left forearm for TST and induration diameter was read 72 hours later For standardization of test the ... 1/3 of one lung area or sum of the dispersed infiltrations was less than a lung area Severe degree lesion; total diameter of the cavities was more than cm or sum of the homogen lesions was more ... the reason of this findings were that female contacts considered their health important, the majority of them have a lot of time because of not working In this study the frequency of TB in household...
Ngày tải lên: 29/03/2014, 03:20
báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
... corrected, power: 1-β = 0.96) for Table 1: Baseline characteristics of patients with severe sepsis and patients with abdominal surgery without signs of infection or inflammation (* unpaired t ... Ray D: Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic ... approval of the local ethics committee and written informed consent of the patient or a legal guardian had been obtained, 169 Caucasian patients with the diagnosis of severe sepsis according to...
Ngày tải lên: 18/06/2014, 15:20