... (P ≤ 0.02) PASI-50 was achieved by 91% (10/11) of the patients at week 10 At the same time point, PASI-75 was achieved by 82% (9/11) and PASI 90 was achieved by 18% (2/11) The body surface area ... 0.02) Mean ICAM-1 expression was reduced by 79% (P ≤ 0.02) and mean VCAM-1 expression was reduced by 44% (P ≤ 0.05) In synovial tissue there was a significant reduction (81%) in the expression of ... the mean *P ≤ 0.05, **P ≤ 0.02, versus baseline The mechanism by which the number of lesional inflammatory cells is decreased by low- dose infliximab in psoriasis and PsA is apparently not induction...
Ngày tải lên: 09/08/2014, 01:23
... sequence (shown below in upper case text) was preceded by an arbitrary sequence (shown below in lower case text) that included an NheI restriction site (underlined) The reverse primer followed a similar ... expression may be enhanced by a negative effect caused by the hyperphosphorylated form, by a positive effect caused by accumulation of the hypophosphorylated form or by a combination of the two ... increased by low concentrations of CDK inhibitors in Chinese hamster ovary (CHO) K1 and human cells by a mechanism involving transcriptional activation and, also in the case of Rb, by an increase...
Ngày tải lên: 16/03/2014, 23:20
Báo cáo khoa học: The activation of gelsolin by low pH The calcium latch is sensitive to calcium but not pH docx
... conformation induced by lowering pH does not allow a tight interaction of G4–6 with G-actin Discussion The pH-dependence of the G2/G4–6 interface Activation of gelsolin by calcium and/or low pH has been ... activated by low pH in an apparently similar manner to that induced by calcium, important differences exist The most striking difference is that the calcium ÔlatchÕ between G2 and that is released by ... is activated by calcium During activation of gelsolin by low pH treatment, a similar unfolding can be recorded using dynamic light scattering [21] and it might be assumed that a low pH also detaches...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: NADH oxidation and NAD+ reduction catalysed by tightly coupled inside-out vesicles from Paracoccus denitrificans doc
... oxidation and NAD reduction catalysed by SPP (Eur J Biochem 269) 4023 Fig The effect of rotenone on the time-course of NADH oxidation (A) and succinate-supported NAD+ reduction (B) catalyzed by tightly ... inhibited by ADPribose, a competitive inhibitor of the mitochondrial enzyme [24] The Ki value for competitive inhibition of the bacterial Fig Kinetics of NADH oxidation and NAD+ reduction by SPP ... Ó FEBS 2002 NADH oxidation and NAD reduction catalysed by SPP (Eur J Biochem 269) 4021 reactions catalysed by the enzyme Unfortunately this information is available only...
Ngày tải lên: 23/03/2014, 21:21
Báo cáo khoa học: Disorder–order transition of k CII promoted by low concentrations of guanidine hydrochloride suggests a stable core and a flexible C-terminus doc
... salts can also cause stabilization of CII, albeit to a lower extent compared with that caused by GdnHCl (Fig 5) The stabilizing effect follows the Hofmeister series of ion [22] Urea, on the other ... relative light scattering, was reduced by more than 50% This result is consistent with a structural compaction of the protein at low GdnHCl leading to a reduction in exposed hydrophobic surfaces ... rate of proteolysis by trypsin can be attributed to an alteration of CII conformation as 0.1 M GdnHCl reduces trypsin activity by a meager 6% (as measured spectrophotometrically by the rate of degradation...
Ngày tải lên: 30/03/2014, 20:20
morphology control of zno bilayer structure by low-temperature
... releases OH− slowly, resulting in a relatively stable environment for crystal growth Due to the sufficient Zn2+ concentration of the refreshed solution, the flower-like structure was assembled by nanorods ... nanorod structure and double nanorods layers structure were obtained by controlling growth concentration and position via low- temperature hydrothermal process The shape evolution of nanodendrite–nanorod ... the seed layer (Fig 2A, B) at 90 1C through the reactions of Zn2+ cations with OH− anions as foolows: NH3 ⋅H2 O⇔NHþ þOH− ð1Þ Zn2þ þOH− -½ZnðOHÞ4 2− -ZnO þ H2 O þ OH− ð2Þ Zn2þ þ NH3 ⋅H2 O-½ZnðNH3...
Ngày tải lên: 06/05/2014, 13:24
Inactivation of gram negative bacteria by low pressure RF remote plasma excited in n2 o2 mixture and SF6 gases
... for low- temperature sterilization J Phys D: Appl 2007;40:803 doi: 10.1088/0022-3727/40/3/017 Pointu AM, Ricard A, Dodet B, Odic E, Larbre J, Ganciu M Production of active species in N2–O2 flowing ... cultures (Difco, BD, Spars, MD), and the cultures were harvested in a sterile PBS and adjusted by spectrophotometry to 1.0×1010 CFU/ml Serial dilutions of 100 µl (1.0×109 CFU/ml) of each freshly ... performed with SPSS statistical program (version 15) A mean value for each bacterial count was obtained by averaging the duplicate values after log conversion Results The best conditions that led to the...
Ngày tải lên: 18/05/2014, 20:36
research on fatigue behavior of welded joint spraying fused by low transformation temperature alloy powder
... shrinkage caused by heat bilges cold shrink of material; Dep is expansion strain caused by martensite phase transformation From formula (1)–(3), Stress–Temperature curves of five kinds of low transformation ... groups: as-welded joint, welded joint spraying fused by conventional nickel base alloy powder (Conventional-joint) and welded joint spraying fused by low transformation temperature alloy powder (LTT-joint) ... chart of welded joint spraying fused by conventional nickel base alloy powder (Conventionaljoint) Fig 12 is stress cloud chart of welded joint spraying fused by low transformation temperature alloy...
Ngày tải lên: 24/05/2014, 20:34
Báo cáo sinh học: " Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats" doc
... and the reduction in antioxidant capability, as well as to investigate the impact of IGF-II therapy on these parameters in aging animals The experimental procedure was performed as follow: healthy ... the fresh liver was used to isolate mitochondria and to perform mitochondrial function tests by flow cytometry Analytical methods in serum Analytical parameters (total protein, glucose, cholesterol, ... serum by routine laboratory methods using an autoanalyzer (Cobas Mira; Roche Diagnostic System, Basel, Switzerland) Serum levels of hormones (testosterone, IGF-I and insulin) were assessed by RIA...
Ngày tải lên: 18/06/2014, 19:20
o cáo hóa học:" Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats" docx
... and the reduction in antioxidant capability, as well as to investigate the impact of IGF-II therapy on these parameters in aging animals The experimental procedure was performed as follow: healthy ... the fresh liver was used to isolate mitochondria and to perform mitochondrial function tests by flow cytometry Analytical methods in serum Analytical parameters (total protein, glucose, cholesterol, ... serum by routine laboratory methods using an autoanalyzer (Cobas Mira; Roche Diagnostic System, Basel, Switzerland) Serum levels of hormones (testosterone, IGF-I and insulin) were assessed by RIA...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: " Wettability Modification of Nanomaterials by Low-Energy Electron Flux" pptx
... as follows: n-hexane, 1-bromonaphthalene, diiodomethane, formamide, ethylene glycol and water They differ by their viscosity, surface tension, polar and dispersive components, etc that allow studying ... Properties of Modified Powders The capillary rise technique [26] allows obtaining exact data on wettability contact angles of powders followed by the application of well-developed thermodynamic approaches ... lv sv p leading the fraction relation to csv cd ¼ 0:55 Low- energy sv electron treatment of diamond particles is characterized by weak reduction in the surface energy and its components (mainly...
Ngày tải lên: 22/06/2014, 00:20
Báo cáo hóa học: " Surface Morphology Evolution of GaAs by Low Energy Ion Sputtering" pdf
... below · 10–4 Torr by a turbo pump All samples are sputtered for 300 s with the ion current kept at 10 mA which is equivalent to 8.8 · 1015 cm–2 s–1 beam flux The surface morphology induced by ... summarized as follows: In the low eV range, no visible feature appears except for surface roughening (Fig 1a) Above the mid-eV energy dot-like patterns start forming, but they are accompanied by the presence ... induced GaAs(100) surface morphology evolution below 1,200 eV ion energy is investigated The sputtered surface is examined and analyzed by AFM In the low eV energy range, no regular surface patterns...
Ngày tải lên: 22/06/2014, 18:20
Báo cáo lâm nghiệp: "Predicting balsam fir growth reduction caused by spruce budworm using large-scale historical records of defoliation" potx
... quantified Moreover, defoliation-induced mortality may be preceded by growth reductions from which patterns of change, as predicted by yearly defoliation, could potentially help estimate volumes ... retain low- frequency variations associated with insect defoliation while removing longer-term growth trend due to ageing Following Fritts [13], each ring-width value was then divided by the value ... records estimated from aerial surveys made annually by the same team of observers As described by Gray et al [14], these defoliation surveys were made by the Ministère des Ressources naturelles et...
Ngày tải lên: 08/08/2014, 00:21
Báo cáo y học: "Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis" pps
... exudates was quantified by HPLC and ELISA, respectively [17] The IL-10 concentration in cell-free inflammatory exudates was quantified by ELISA (R&D Systems, Minneapolis, MN, USA) following the manufacturer's ... of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules Clin Immunol 2005, 114:154-163 Cronstein BN: Low- dose methotrexate: a mainstay ... regulated by different cellular mechanisms, we determined whether the A2A and A3 receptors played similar roles in regulating inflammation in the peritoneum We examined the pharmacologic mechanism by...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo khoa học: " Chemotherapy followed by low dose radiotherapy in childhood Hodgkin''''s disease: retrospective analysis of results and prognostic factors" ppt
... response with chemotherapy followed by Low dose-IFRT or no further therapy Complete response was defined as an absence of residual tumor or residual tumor that showed a reduction in size of 70% or ... was cervical lymph node enlargement, seen in 71% The histology was nodular sclerosis 48.1%, followed by mixed celularity 34.3%, lymphocyte depletion 1.8 % and lymphocyte predominant 15.6% Radiotherapy ... in fifteen years of follow-up The cases of second tumors included two cases of thyroid carcinoma and one case of breast cancer All cases were treated conformed protocols by cancer site Discussion...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Sustained eradication of hepatitis C virus by low-dose long-term interferon therapy in a renal transplant recipient with dual infection with hepatitis B and C viruses: a case report" pptx
... one year with treatment regimens of isoniazid, rifampin, and ethambutol for three months, followed by isoniazid alone for seven months His liver biochemistry tests (aspartate aminotransferase, ... copy of the written consent is available for review by the Editor-in-Chief of this journal Acknowledgements Financial support was provided by Chang Gung Memorial Hospital, Taoyuan, Taiwan (CMRPG370931G ... doi:10.1186/1752-1947-5-246 Cite this article as: Chang et al.: Sustained eradication of hepatitis C virus by low- dose long-term interferon therapy in a renal transplant recipient with dual infection with...
Ngày tải lên: 10/08/2014, 23:21
Báo cáo y học: " Improvement of pain and regional osteoporotic changes in the foot and ankle by low-dose bisphosphonate therapy for complex regional pain syndrome type I: a case series" pptx
... a marked reduction in radioactivity to a level comparable to that in the normal, left ankle (Figure 3) In addition, the effect of bisphosphonate on bone pain relief correlated with a reduction ... in his Figure Change in bone pain (visual analog scale, or VAS) The reduction in VAS score after the oral administration of low doses of bisphosphonate Aln, duration of treatment with alendronate ... arrow) (C) Figure Changes in bone pain (visual analog scale, or VAS) The reduction in VAS score after the oral administration of low doses of bisphosphonate Aln, duration of treatment with alendronate...
Ngày tải lên: 10/08/2014, 23:22
Two dimensional molecular self assemblies on surfaces studied by low temperature scanning tunneling microscopy
... discussions and helpful suggestions gave by Prof Andrew T S Wee during my research His in-depth reviews of my every manuscript and also this thesis word by word despite his busy schedule also gave ... self-assemblies on surfaces and their formations of regular supramolecular arrays are demonstrated by low- temperature scanning tunneling microscopy (LT-STM) in ultra-high vacuum (UHV) environments ... networks, whose overall arrangements could be tuned by varying molecular intermixing ratios as well as molecular building blocks, are constructed by co-adsorption of F16CuPc with copper phthalocyanine...
Ngày tải lên: 11/09/2015, 09:58
ZnO nanostructures grown by low temperature method
... the activation of H in the material; and the reduction of defect emission by plasma treatment is due to the reduction of surface defects ALD as another low temperature synthesis method to obtain ... phase synthesis methods In a typical process, vapor species are first generated by evaporation followed by chemical reduction or oxidation if necessary These species are subsequently transported ... used for ZnO ECD Another way to obtain ZnO nanowires is by electrodeposition of Zn followed by oxidization.63,64 In 31 this work done by Le et al , AAO membrane with highly ordered nanopores...
Ngày tải lên: 14/09/2015, 08:50
Human capital accumulation by low skilled workers with borrowing constraints a welfare analysis based on the lucas rural urban migration model
... borrowing constraint faced by low- skilled workers by subsidizing their migration to cities and financing the subsidy with increased future income-tax revenue produced by an expanded highskilled ... their consumption by borrowing from future employment income, which is expected to grow with human capital When the financing constraint is binding, the low- skilled workers must lower current consumption ... accumulation by low- skilled workers but are omitted in Lucas (2004) Workers must allocate time to learning in order to accumulate human capital, forgoing employment income Absent borrowing constraints, low- skilled...
Ngày tải lên: 16/09/2015, 12:15