nonmetastatic effects of cancer other systems

... (Nordberg 2011) The issues of board structure and processes, defined in terms of board size, the establishment of various committees, the separation of the posts of the chairman of the board and the ... director of another company and otherwise Second, IEit is defined as the number of non-executive directors on the board who are also executive directors at other companies The elements of vector ... executive directors of other firms to total number of non-executive directors Number of IE directors is the number of non-executive directors on a board who are executive directors in other companies...

Ngày tải lên: 21/02/2014, 17:20

... Lebowitz, Professor of Internal Medicine, University of Arizona College of Medicine, Division of Respiratory Sciences, Tucson, AZ 85724 Dr Howard Rockette, Professor of Biostatistics, School of Public ... assessment of the respiratory health effects associated with passive smoking has been prepared by the Human Health Assessment Group, Office of Health and Environmental Assessment, Office of Research ... the Office of Health and Environmental Assessment (OHEA) within the Office of Research and Development, with major contract funding provided by the Indoor Air Division within the Office of Air...

Ngày tải lên: 15/03/2014, 01:20

... observations of parental expressions of grief made it likely that cases of reported deaths were accurate Second, adoption of some critical assumptions when calculating DALYs was unavoidable; the choice of ... Validation of postmortem interviews to ascertain selected causes of death in children International Journal of Epidemiology, 19:380-386 Killewo J Z and Smet J E (1989) Mothers' definition of diarrhoea ... frequently Respondent mothers easily understand its definition, and there is little variation of symptoms from mothers’ perceptions (Killewo and Smet 1989): the occurrence of or more loose, watery...

Ngày tải lên: 05/09/2013, 10:15

... agro-ecosystems The main objective of this paper was to quantify the effects of reuse of biosolids (in the form of animal manure) as nutrient sources by: (i) investigating the effects of biosolids ... long-term use of effluents for agricultural purposes due to the likelihood of phytotoxicity, health and environmental effects [17, 33] Even after a short-term application of biosolids, the level of trace ... Science of the Total Environment 67 (1987) 117 [17] S.P McGrath, Effects of heavy metals from sewage sludge on soil microbes in agricultural ecosystems, in Toxic metals in soil-plants systems, ...

Ngày tải lên: 05/03/2014, 16:20

... were threefold: first, to explore the in vitro effects of CDO alone in a panel of three colorectal cancer cell lines; second, to investigate the effects of combining CDO with etoposide (VP16), 5-fluorouracil ... basis of a future publication Nevertheless, it appears that clinically, the cytostatic ability of CDO could improve and enhance the conventional cytotoxic effect of other chemotherapies in some cancers ... Combining CDO with any chemotherapeutic drug resulted in changes in protein levels that appeared to be similar, irrespective of the chemotherapy used Consequently, the effects of 5-FU on the cell lines...

Ngày tải lên: 07/03/2014, 15:20

... assessing  environmental  risks  of applying  wastewater  in agro‐ecosystems.  The  main  objective  of this  paper  was  to  quantify the effects of reuse of wastewater as  nutrient  sources  ... the  long‐term  use  of effluents for agricultural purposes due to the  likelihood  of phytotoxicity,  health  and  environmental  effects [1,  14].  Another  problem  of wastewater  disposal  ... agricultural land is the potentially phytotoxic  nature of organic wastes, mainly as a result of combination of factors such as high salinity or  excess of ammonium ions, organic compounds  or  low  molecular ...

Ngày tải lên: 14/03/2014, 15:20

... of second languages: high familiarity with English, some knowledge of Arabic, and little or no prior knowledge of Dutch Also, the majority of them found the transliteration of English terms of ... transliterators perception of the task (Easy or Medium) vestigated the transliterator’s perception of difficulty of the transliteration task with the ensuing word accuracy of the systems Interestingly, ... transliterators were not told of the origin of each word The entire corpus, therefore, was easily separated into three sub-corpora of 500 words each based on the origin of each word To distinguish...

Ngày tải lên: 23/03/2014, 18:20

... risks, with 3·2% of the cumulative risk of cancer attributable to diagnostic X-rays, equivalent to 7587 cases of cancer per year In all other populations less than 2% of the cumulative cancer risk ... estimation of number of radiation-induced cases for all cancers is not possible, since estimates of organ-specific doses are not available for other cancers Table 3: Estimated number of radiation-induced ... Extension to all cancers For each of the nine cancer types mentioned, we had all the necessary information to calculate site-specific radiation-induced cancer risks For other solid cancers, neither...

Ngày tải lên: 29/03/2014, 01:20

... target in cancer therapy [24–26] The aim of this study was to investigate the antioxidant effects of PycnogenolÒ on redox enzymes, with emphasis on the regulation of TrxR Results Effects of PycnogenolÒ ... Effects of PycnogenolÒ on redox systems V Gandin et al important constituents of fruits, vegetables and other plants [3] PycnogenolÒ has been shown ... affect the enzyme activity of GR (Fig 1C) The reduction of TrxR and GPx activity was dose-dependent, with maximal effects achieved at concentrations of PycnogenolÒ of 15 lgÆmL)1 for TrxR and...

Ngày tải lên: 30/03/2014, 02:20

... epidemiology of cancer pain and of its treatments, the quality of analgesic-drug therapy and the effect of alternative analgesic strategies in a large, prospective, unselected cohort of cancer patients ... prevalence of pain in advanced cancer is about 70% with ample variations according to the cancer type and disease stage [2] Despite the existence of published and well-known guidelines for cancer ... state -of- the art of patient-reported- Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2006, 4:7 http://www.hqlo.com/content/4/1/7 Table 1: Schedule of assessments...

Ngày tải lên: 20/06/2014, 15:20

... analysis of OFDMA uplink systems with symbol timing misalignment,” IEEE Communications Letters, vol 7, no 8, pp 376–378, 2003 [4] I R Capoglu, Y Li, and A Swami, “Effect of Doppler spread in OFDM-based ... time-variant transfer function of the channel Hl (n, m): Time-variant transfer function of the channel J0 (·): Zeroth-order Bessel function of the first kind STO nδ : N: Number of subcarriers NG : Cyclic ... comments and suggestions in improving the quality of this paper REFERENCES [1] J Li and M Kavehrad, “Effects of time selective multipath fading on OFDM systems for broadband mobile applications,” IEEE...

Ngày tải lên: 21/06/2014, 22:20

... between HMM and CP-OFDM about ∼ dB at SNR = 30 dB and CFO in the range of −0.5 ∼ 0.5 Effects of both CFO and TO on the SINR performance of hexagonal multicarrier systems and CP-OFDM systems at SNR ... transmission systems obtain lower energy perturbation, hence outperform OFDM and LOFDM systems from the robustness against channel dispersion point of view Synchronization is considered as a key factor of ... (2D) case Specifically, in OFDM system with symbol period T and subcarrier separation F, the transmission functions of OFDM system consist of translations and modulations of a single prototype g(t),...

Ngày tải lên: 21/06/2014, 22:20

... Adjunct Professor of University of Toronto and is Honorary or Visiting Professor of over ten universities Int J Med Sci 2004 1(3): 137-145 142 Chi-Hin Cho, PhD, is Chair Professor of Pharmacology ... Officer of CK Life Sciences Limited Dr Pang was the Head of Department of Physiology at University of Hong Kong prior joining the company He had been the founding Editor and Editor-in-Chief of ... the effect of CKBM-A01 (a combined recipe of the above mentioned Chinese herbs and yeast) on the growth of human gastric cancer using a unique subcutaneous implantation model of gastric cancer tissue...

Ngày tải lên: 08/08/2014, 18:20

... its role in cancer progression to improve the opportunities of cancer therapy, especially the effectiveness of radiotherapy It is well known that OPN plays an important role in breast cancer Several ... are increased in many tumors such as lung cancer [21], esophageal cancer [22], prostate cancer [23], glioma [24], soft tissue sarcoma [25] and breast cancer [5,14] Furthermore, it has been shown ... siRNAs Mix is a pool of four siRNAs and might cause more off-target effects than OpnS which could reverse the original effects We chose the siRNA technology for transient inhibition of OPN expression...

Ngày tải lên: 09/08/2014, 09:20

... irradiation sensitizer in gastric cancer therapy Guidelines of the NCCN on gastric cancer Figure Quantification of mRNA expression of different genes Analysis of mRNA expression of COX-2, VEGF and EGFR ... EGFR genes in gastric cancer cells, which was mainly due to the decrease in expression of NF-B via inhibited b-ARs Discussion Gastric cancer is one of the major causes of cancer mortalities in ... together, radiotherapy in combination with propranolol can be more useful for patients with a high risk of recurrence in gastric cancer Investigation of the specific mechanisms of NF-B activation...

Ngày tải lên: 09/08/2014, 09:20

... next evaluated the potential of ErPC3 to inhibit the survival kinase Akt in PC3 and LNCaP prostate cancer cells Moreover, we compared the effects of ErPC3 to the effects of the PI3K inhibitor LY294002 ... that a down-regulation of p-Akt may be required for the anti-neoplastic action of small molecule inhibitors of the PI3K/Akt pathway in prostate cancer cells Combined effects of ErPC3 and ionizing ... number of viable LNCaP cells When irradiation was combined with subtoxic concentrations of ErPC3, the anti-neoplastic effects of the combined treatment were mainly due to the effects of ionizing...

Ngày tải lên: 09/08/2014, 09:20

... hydrolyses a variety of proteins and activates other MSPs and MMPs [8,9] TATI is a trypsin inhibitor that balances concentrations of trypsin and also functions as a weak inhibitor of other serine proteinases ... of any previous studies describing the effects of RT on the tumour-specific expression of TATI or its serum concentrations in any cancer form, the aim of the present study was to investigate ... further supports the potential utility of TATI as a prognostic biomarker in patients with cancer of the colon and rectum, irrespective of neoadjuvant RT Page of 10 Additional material Additional...

Ngày tải lên: 09/08/2014, 09:21

... wall due to gravity With CT density values of the rectal wall often very similar to the density of the filling a precise delineation of the inner contour of the rectal wall was difficult for some ... treatment of prostate cancer Int J Radiat Oncol Biol Phys 1997, 37(1):3-11 Leibel SA, Hanks GE, Kramer S: Patterns of care outcome studies: results of the national practice in adenocarcinoma of the ... Meyer L, Nahum A, Tait D, Yarnold J, Horwich A: Comparison of radiation side -effects of conformal and conventional radiotherapy in prostate cancer: a randomised trial Lancet 1999, 353(9149):267-272...

Ngày tải lên: 09/08/2014, 10:21

... expression profiles of miRNAs are informative for the classification of human cancers Based on miRNA-expression profiles, Lu et al [13] reported the classification of 334 leukemia and solid cancers ... hsa-miR-517a hsa-miR-769-5p RE-score profiles of microRNAs for the classification of ER+ and ER- breast tumors Figure RE-score profiles of microRNAs for the classification of ER+ and ER- breast tumors ... interferon, which results in the inhibition of Dicer expression Another possible explanation of the low expression of Dicer in ER- cancers may be the regulatory effect of miRNAs DICER's epigenetic regulation...

Ngày tải lên: 09/08/2014, 20:20

... effects of somatostatin on XAF1 in prostate cancer cells Journal of Experimental & Clinical Cancer Research 2010 29:162 Submit your next manuscript to BioMed Central and take full advantage of: ... up-regulated the expression of SSTR1-5, and that apoptosis was activated mainly via the induced expressions of SSTR2 and SSTR3 The effects of somatostatin on the prostate cancer cells may be mediated ... up-regulation of XAF1 mediated by somatostatin and Octreotide triggers cancer cell apoptosis Conclusions To our knowledge, little is known about the regulatory effects of XAF1 in many different types of...

Ngày tải lên: 10/08/2014, 10:20