nodal metastasis in the neck from squamous cell carcinoma

... Metastases from Squamous Cell Carcinoma of the Cervix as Reported in the Literature (PubMed and Medline available since 1981) – search terms: squamous cell carcinoma AND “cervix”/ carcinoma cervix” ... nonkeratinizing squamous cells(*) similar to the cells seen in Figure 2a(*) 3b: Photomicrograph of staining with Cytokeratin shows strong cytoplasmic and membrane staining of the lesional cells ... membrane staining of the lesional cells (*) as seen in Figure 2b 4c: Photomicrograph of staining with P63 shows strong nuclear staining of the cells (*) as seen in the duodenal biopsy in Figure...

Ngày tải lên: 09/08/2014, 02:21

... strong positive membranous staining of the lesional cells (1E, black arrow); cytokerain (CK7) demonstrates the strong positive staining of the lesional cells in the subpleural lymphatics (1F, ... al: Usefulness of p16 for differentiating primary pulmonary squamous cell carcinoma from cervical squamous cell carcinoma metastatic to the lung Am J Clin Pathol 2009, 131(5):715-22 10 Anraku ... by detecting the ‘beaded chain’ appearance due to uneven thickening in the septa of the lung secondary to lymphatic vessels, demonstrating cell infiltration [3,4] Bronchoscopy with washings and...

Ngày tải lên: 09/08/2014, 03:23

... The checkpointkinase (CHK2) 1100delC germ line mutation is not associated with the development of squamous cell carcinoma of the head and neck (SCCHN) Journal of Negative Results in BioMedicine ... the risk of predisposing CHK2 mutations In the present study, we did not find the CHK2 1100delC variant in any of these patients Moreover, patients suffering from multiple tumor types including ... http://www.jnrbm.com/content/9/1/10 other than 1100delC in SCCHN as well as the definition of the role of CHK2 in the carcinogenesis of SCCHN remain to be an interesting matter for future investigations Abbreviations...

Ngày tải lên: 11/08/2014, 07:21

... seroprevalence in individuals engaging in high-risk sexual activity, including homosexual men, indicates the role of sexual behaviour in the transmission of the infection in adults [4] On the other hand, the ... squamous cell carcinoma The lesion's clinical presentation, its location, the otherwise normal skin, and the lack of any predisposing factors with the exception of the patient's origin, were misleading ... was in otherwise good health, with no predisposing factors or conditions requiring medication Clinically, the lesion resembled a squamous cell carcinoma Due to the size and presentation of the...

Ngày tải lên: 11/08/2014, 21:22

... gelatin matrix remained as a fine particulate suspension in both normal and sanguineous urine so that the implications of these findings with regard to sealing the renal parenchyma or the collecting ... further studies to improve the design of these agents in future Moreover, additional investigations will clarify the indications and the best HAs to choose Looking to the future, minimally invasive ... [31,32] As the indications for topical HAs increase in urology, the question arises about what happens to these agents when they enter the urinary collecting system It has been shown that fibrin glue...

Ngày tải lên: 09/08/2014, 03:21

... those in the posterior region can stimulate the emetic impulse, and can obstruct the passage of a bolus during swallowing, and induce nausea and vomiting in this manner Despite the fact, that in the ... like the University of Washington (UW) Head and Neck Disease-Specific Measure, the Medical Short Form 36 and the EORTC-H&N35, the latter was more sensitive in detecting changes in the single ... and neck malignancies The questionnaire is a supplement to the QLQ-C30, and contains 35 questions There are scaled answers for pain, swallowing, sensibility, speech, eating in a social setting,...

Ngày tải lên: 11/08/2014, 20:20

... malignancy involving the parotid gland Head Neck 2001, 23:744-748 Joseph MG, Zulueta WP, Kennedy PJ: Squamous Cell Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their ... Prognostic factors for metastasis is squamous cell carcinoma of the skin Dermatol Surg 2002, 28:268-73 Ames FC, Hickey RC: Metastasis from squamous cell skin cancer of the extremities South Med ... Invasive squamous cell carcinoma of the skin: Defining a high-risk group Ann Surg Oncol 2006, 13:902-909 Johnson TM, Rowe DE, Nelson BR, Swanson NA: Squamous cell of the skin (excluding lip and oral...

Ngày tải lên: 09/08/2014, 07:21

... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1497-1503 Adelstein DJ, Li Y, Adams ... proportion score was multiplied by the staining intensity to obtain a final semi-quantitative H score The median value of the H score was chosen as the cutoff point for separating low and high levels of ... cause inter- and intrastrand cross-linking These DNA cross-links are recognized and removed by the nucleotide excision repair pathway which arms to guard the integrity of the genome [15,16] The...

Ngày tải lên: 18/06/2014, 19:20

... compared to the normal tissues This in contrary to the results obtained in hepatocellular carcinoma, but clearly in line with the studies in other types of cancer to date A highly significant link was ... the clinical implications of MTSS1 expression in oesophageal squamous cell carcinoma We also provide new insights into the biological functions of MTSS1 and its role in oesophageal squamous cell ... methods Cell lines and human oesophageal specimens This study used three human oesophageal squamous cell carcinoma cell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated cell...

Ngày tải lên: 18/06/2014, 19:20

... staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of the ... cytoplasmic staining, we scored both the intensity (0 (negative) to (strong)) and the percentage of tumor cells with the dominant intensity staining pattern (0 (none) to 4) These two scores were then multiplied ... the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, using the same scoring system as applied for Her2, and the cytoplasm For the...

Ngày tải lên: 18/06/2014, 22:20

... immunohistochemical staining Stained sections were reviewed by one of the authors (AB) The percentage of tumor cells showing a positive membranous/cytoplasmatic staining and the intensity of staining were ... causing a threonine/isoleucine switch at amino acid location Thr399Ile (rs4986791) These polymorphisms alter the amino acid sequence of the TLR4 protein and affect the extracellular domain and ... research use of the tissues and for participating in the research project The study was conducted according to the Declaration of Helsinki Tissues were obtained during diagnostic or therapeutic surgery...

Ngày tải lên: 18/06/2014, 22:20

... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1497-1503 Adelstein DJ, Li Y, Adams ... proportion score was multiplied by the staining intensity to obtain a final semi-quantitative H score The median value of the H score was chosen as the cutoff point for separating low and high levels of ... cause inter- and intrastrand cross-linking These DNA cross-links are recognized and removed by the nucleotide excision repair pathway which arms to guard the integrity of the genome [15,16] The...

Ngày tải lên: 20/06/2014, 03:20

... compared to the normal tissues This in contrary to the results obtained in hepatocellular carcinoma, but clearly in line with the studies in other types of cancer to date A highly significant link was ... the clinical implications of MTSS1 expression in oesophageal squamous cell carcinoma We also provide new insights into the biological functions of MTSS1 and its role in oesophageal squamous cell ... methods Cell lines and human oesophageal specimens This study used three human oesophageal squamous cell carcinoma cell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated cell...

Ngày tải lên: 20/06/2014, 04:20

... staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of the ... cytoplasmic staining, we scored both the intensity (0 (negative) to (strong)) and the percentage of tumor cells with the dominant intensity staining pattern (0 (none) to 4) These two scores were then multiplied ... the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, using the same scoring system as applied for Her2, and the cytoplasm For the...

Ngày tải lên: 20/06/2014, 04:20

... immunohistochemical staining Stained sections were reviewed by one of the authors (AB) The percentage of tumor cells showing a positive membranous/cytoplasmatic staining and the intensity of staining were ... causing a threonine/isoleucine switch at amino acid location Thr399Ile (rs4986791) These polymorphisms alter the amino acid sequence of the TLR4 protein and affect the extracellular domain and ... research use of the tissues and for participating in the research project The study was conducted according to the Declaration of Helsinki Tissues were obtained during diagnostic or therapeutic surgery...

Ngày tải lên: 20/06/2014, 04:20

... chemotherapy or radiotherapy is not helpful in improving survival [4-6] In the review of the literature from 1976 through to 2005, the optimal debulking rate for carcinoma in situ was 100% and the ... prognostic factors [10] Due to the relative rarity of the squamous cell carcinoma in situ arising in MCT, there is no uniform consensus regarding treatment However, the treatment for many authors ... Figure Squamous cell carcinoma in situ (G × 300): Atypical cells on all the epithelial height with an architectural disorganization The basal membrane is intact and the chorion is free Conclusion Squamous- cell...

Ngày tải lên: 20/06/2014, 07:20

... of squamous cell carcinoma with intradural spinal metastasis in which the initial symptoms appeared in the spinal cord and cauda equina, but not in the brain Author Age Gender Primary tumor Involved ... with intradural spinal metastasis in the lumbar spine [12] We found no reports of a patient with intradural squamous cell carcinoma in the sacrum Their primary lesions included the lung in patients, ... transformed into squamous cell carcinoma have been reported [14,15], the patient mentioned above was the only one in whom the cyst had transformed into spinal carcinoma These data indicate that...

Ngày tải lên: 09/08/2014, 04:21

... 6) The protein level of cdc2 increased from 12 h after BNCT, and this was maintained until 48 h An increase in the phosphorylation of cdc2 occurred at 12 h, indicating cell cycle arrest at the ... the G2 checkpoint, and declined to the initial level at 48 h Cyclin B1 that forms the cdc2/cyclin B1 complex was induced at 12 h after BNCT In SAS/mp53 cells, the expression of Wee1 increased at ... in BNCTtreated cancer cells should be clarified p21 binds to and inhibits the cyclin-dependent protein kinases that drive the cell cycle, and is responsible for G1 arrest [34-36] In SAS/neo cells,...

Ngày tải lên: 09/08/2014, 10:20

... amino acids (Invitrogen) and 1% penicillin and streptomycin (Invitrogen) The growth medium was changed every second day The passage of the cells was performed by trypsination (trypsin 1×, Invitrogen) ... neck cancer cells seem to display cell toxic effects at concentrations comparable to other cancer cells, e.g cervical adenocarcinoma cells [43], osteosarcoma cells [42], lung adenocarcinoma cells ... saline (PBS, Oxoid, Hampshire, United Kingdom) and incubated overnight with fresh growth medium containing BrdU-labeling agent BrdU, which is incorporated only in viable cells during DNA synthesis,...

Ngày tải lên: 11/08/2014, 00:23

... SCC of the nipple should be included in the differential diagnosis of a nipple lesion in a patient presenting after radiation therapy Other diagnoses to consider include basal cell carcinoma, ... fold-increase in risk for NMSC (SCC and basal cell carcinoma) Of these cancers 90% occurred within the radiation field [10] The association between radiation and NMSC is also prevalent in the ... cell carcinoma Competing interests The authors declare that they have no competing interests Authors' contributions CLJ reviewed the literature and wrote the manuscript KJR carried out the operation...

Ngày tải lên: 11/08/2014, 12:20