... Sergio Cossu11, Alessandro Bulfone1, Paolo Cossu Rocca5, Maria Rosaria De Miglio5 and Sandra Orrù4 Abstract Background: To provide further information on the clinical and pathological prognostic ... cancer (TNBC), for which limited and inconsistent data are available Methods: Pathological characteristics and clinical records of 841 TNBCs diagnosed between 1994 and 2015 in four major oncologic ... The HRs were 3.13, 9.65, and 29.0, for stage II, III and IV, respectively, vs stage I Necrosis and Ki-67 > 16% were also associated with increased mortality (HR: 1.61 and 1.99, respectively) Patients
Ngày tải lên: 24/07/2020, 00:13
... Blood, by Paul Ehrlich and Adolf Lazarus 1 HISTOLOGY OF THE BLOOD NORMAL AND PATHOLOGICAL. London: C. J. CLAY AND SONS, CAMBRIDGE UNIVERSITY PRESS WAREHOUSE, AVE MARIA LANE, AND H. K. LEWIS, 136, ... numbers and equations, carats before bracketed numbers denote a superscript. Minor typos have been corrected. HISTOLOGY OF THE BLOOD NORMAL AND PATHOLOGICAL BY P. EHRLICH AND A. LAZARUS. EDITED AND ... position and nature of these seats of election for special proteid and other poisons. The researches of Metschnikoff, of Kanthack and Hardy, of Muir, of Buchanan, and others, are supplementary and
Ngày tải lên: 17/02/2014, 22:20
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf
... Acknowledgements We thank past and present members of the Stuehr lab for their efforts and valuable discussions, and National Institutes of Health grants GM51491, CA53914 and HL76491 for financial support ... both an electron acceptor (receiving electrons from FAD) and an electron donor, and is thought to undergo large conformational movements and engage in two distinct protein–protein interactions ... from FADH2) and an electron donor (transferring an electron typically from FMNH)), and is thought to undergo large conformational movements in the process How this process occurs and is regulated
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling pptx
... MINIREVIEW Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling Sam Hay, Christopher R Pudney and Nigel S Scrutton Manchester Interdisciplinary Biocentre and Faculty of ... [4,13,14] and flavoprotein [8,15–20] systems Using a combination of experimental and computational approaches, we have shown that H-transfer reactions can occur by ‘deep’ tunnelling and the reaction ... denote H+, H• and H)) ˚ is $1 A and thus similar to a typical bond length, whereas thepffiffiffi wavelength of deuterium is shorter by a factor of $ As a consequence, the position of H (and to a lesser
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+ doc
... stabilize protein– flavin complexes and tailor the midpoint potentials in these proteins, as well as many details of the binding and electron transfer to protein and ligand partners, have been revealed ... interaction and electron transfer with PSI [53,84,88–90] Many of these Fld mutants (T12V, E16Q, T56G, W57 replaced by K, R, F, L, A and Y, I59 replaced by A and K, Y94 replaced by A and F, N97K, ... chloroplasts, phototropic and heterotrophic bacteria, apicoplasts, and animal and yeast mitochondria [139] Two unrelated families of proteins can be found in these enzymes: the plant type and the glutathione
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface pdf
... pro- and anti-angio- genesis. However, during the course of pathological conditions such as ischemia and tumor growth, VEGF contributes to break the BBB and promote endothelial permeability and ... (e.g. hypoxia-inducible factor and Src-suppressed C kinase substrate ⁄ AKAP12) and soluble factors (e.g. vascular endothelial growth factor and angiopoie- tin-1), as well as axon guidance molecules and neurotrophic ... trans- ferrin and leptin, to cross the BBB [13]. Molecular basis of brain angiogenesis and barriergenesis Hypoxia and the hypoxia-inducible factor system As an embryo develops and its structure
Ngày tải lên: 18/02/2014, 11:20
International public sector accounting standards (IPSAS) impact and compliance aspects
... Standards (IPSAS) Impacts and Compliance Aspects International Public Sector Accounting Standards (IPSAS) Table of Contents Public Sector Accounting and Financial Reporting Standards Boards and ... understanding of such IPSAS standards and does not constitute legal advice, and SAP AG and all of its affiliated companies (“SAP Group”) make no warranty or representation of any kind and disclaim ... the world Standards Boards and Frameworks Historically, local, state, and federal governments and other public sector entities have exercised jurisdictional powers to set individual standards for
Ngày tải lên: 14/03/2014, 00:02
The Body Systems: Clinical and Applied Topics ppt
... ductus deferens, ejaculatory duct, and urethra), accessory glands (the seminal vesicles, prostate, and bulbourethral glands), and the exter- nal genitalia (penis and scrotum). The female reproductive ... uterine tubes, uterus, and vagi- na), accessory glands (the greater and lesser vestibular glands), the external genitalia (the cli- toris, labia majora and labia minora), and sec- ondary sexual ... inserted into the rectum and pressed against the anterior rectal 164 The Body Systems: Clinical and Applied Topics 1 9 wall to palpate the posterior walls of the prostate gland and seminal vesicles.
Ngày tải lên: 14/03/2014, 16:20
Biochemical and physiological aspects of human nutrition units i & II
... Thiamin Thiamin and Thiamin Coenzyme Structure and Nomenclature Sources, Digestion, and Absorption 476 Transport and Conversion of Thiamin to Coenzyme 476 Thiamin Catabolism and Excretion ... Riboflavin, and T h i a m i n Donald B McCormick, Ph.D 458 Niacin Niacin and Pyridine Nucleotide Coenzyme Structure and Nomenclature 459 Sources, Digestion, and Absorption 460 Transport and ... Chemistry and Physical Properties of Vitamin A and Carotenoids 600 Physiological Functions of Vitamin A 602 Absorption, Transport, Storage, and Metabolism of Vitamin A and Carotenoids
Ngày tải lên: 16/03/2014, 18:07
Clinical and Molecular Advances in Ankylosing Spondylitis Edited by Jacome Bruges-Armas doc
... original research and revised chapters, to update the clinical and molecular knowledge of AS and SpA The chapters in the first section, ? ?Clinical Manifestations, Bone Density Measurements and Axial Fractures ... clinician, to check and control spinal function and flexibility The chapter on the incidence, clinical features, pathophysiology, signs, symptoms, and current management of the Temporomandibular Joint ... CLINICAL AND MOLECULAR ADVANCES IN ANKYLOSING SPONDYLITIS Edited by Jacome Bruges-Armas Clinical and Molecular Advances in Ankylosing Spondylitis
Ngày tải lên: 17/03/2014, 02:20
IMPROVING MATERNAL MORTALITY AND OTHER ASPECTS OF WOMEN''''S HEALTH docx
... design and conduct mortality reviews in individual health facilities and in communities, and to measure the impact and effectiveness of programs to reduce maternal mortality and ... and other aspects of women’s health past events and should encourage action by the same participants to address identified challenges Verbal and. .. reliably certify deaths and ... violence, integration of family planning into PEPFAR and other HIV/AIDS programs, and women’s health and maternal mortality. See Janet Fleischman, HIV and Family Planning Integration in Tanzania: Building
Ngày tải lên: 22/03/2014, 11:20
PULMONARY TUBERCULOSIS IN HIV INFECTION IN TANZANIA clinical and immunological studies pdf
... bronchoscopy and infectious diseases at Cologne University Hospital, Germany in 1998, and in advanced gastrointestinal endoscopy and bronchoscopy in The Netherlands in 2001 and 2003, and in The ... Mrs E Ngomuo and Mr G Kisyombe for their relentless laboratory support at KCMC Department of Clinical Microbiology To Dr B Mulder and the staff of Laboratory for Medical Microbiology and Public ... colleagues and staff of KCMC Department of Internal Medicine, and especially the nurses of the Endoscopy Unit for the co-operation and support To PRIOR management for their vision and patronage
Ngày tải lên: 22/03/2014, 18:20
In Vitro Fertilization – Innovative Clinical and Laboratory Aspects Edited by Shevach Friedler potx
... Fertilization – Innovative Clinical and Laboratory Aspects granulose cells and regulate oocyte maturation (Alviggi et al., 2006) LH is also secreted in the theca compartment and induces androgen production ... Fertilization – Innovative Clinical and Laboratory Aspects stimulating hormone efficacy and improves ovulation induction outcome The Journal of Clinical Endocrinology and Metabolism Vol 84, No ... Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and 28 In Vitro Fertilization – Innovative Clinical and Laboratory Aspects endometrial...
Ngày tải lên: 16/03/2014, 21:21
IN VITRO FERTILIZATION – INNOVATIVE CLINICAL AND LABORATORY ASPECTS pdf
... Fertilization – Innovative Clinical and Laboratory Aspects granulose cells and regulate oocyte maturation (Alviggi et al., 2006) LH is also secreted in the theca compartment and induces androgen production ... Fertilization – Innovative Clinical and Laboratory Aspects stimulating hormone efficacy and improves ovulation induction outcome The Journal of Clinical Endocrinology and Metabolism Vol 84, No ... Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and 28 In Vitro Fertilization – Innovative Clinical and Laboratory Aspects endometrial...
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POSITRON EMISSION TOMOGRAPHY – CURRENT CLINICAL AND RESEARCH ASPECTS pdf
... #/gate/output/root/setRootdelayFlag # RANDOM #JamesRandom Ranlux64 MersenneTwister /gate/random/setEngineName Ranlux64 #/gate/random/setEngineSeed default #/gate/random/setEngineSeed auto /gate/random/setEngineSeed ... the clinical target volume (CTV) and PTV, the physician’s prescription, and the delivered dose (Mackie & Gregoire, 2010; Palta & 30 Positron Emission Tomography – Current Clinical and Research Aspects ... monolithic crystals and depth-of-interaction encoding from a user's perspective 26 Positron Emission Tomography – Current Clinical and Research Aspects Measurement Science and Technology, Vol...
Ngày tải lên: 27/06/2014, 13:20
TRENDS IN ALCOHOLIC LIVER DISEASE RESEARCH – CLINICAL AND SCIENTIFIC ASPECTS pot
... Research – Clinical and Scientific Aspects Wood, B , Breen, K.J (1979) Vitamin deficiency in alcoholism with particular reference to thiamine deficiency Clinical and Experimental pharmacology and Physiology ... retinol dehydrogenase) and is essential for macronutrient metabolism (e.g 12 Trends in Alcoholic Liver Disease Research – Clinical and Scientific Aspects carbohydrate and protein metabolism), ... E, and folate as well as minerals like zinc and iron as well as skin turgor, poor oral health and temporal muscle wasting or night 14 Trends in Alcoholic Liver Disease Research – Clinical and...
Ngày tải lên: 27/06/2014, 16:20
GLAUCOMA – CURRENT CLINICAL AND RESEARCH ASPECTS potx
... Stephen G Schwartz and Tomomi Higashide Chapter 12 Drops, Drops, and More Drops John Walt and Fern Alexander Chapter 13 Pressure Lowering Medications Liza-Sharmini Ahmad Tajudin and Yaakub Azhany ... examines bench- and animal-modeling research in an attempt to understand the pathogenesis of glaucoma The clinical science section addresses various diagnostic issues and the medical, laser and surgical ... Glaucoma – Current Clinical and Research Aspects in complement activation and inflammatory cytokine/chemokine production, which in turn cause abnormal leukocyte-endothelial interactions and ultimately...
Ngày tải lên: 27/06/2014, 18:20
AN UPDATE ON GLOMERULOPATHIES – CLINICAL AND TREATMENT ASPECTS pptx
... Etiology and Pathogenesis In 24 concise, focused and well-formulated chapters the broad scope of clinical and therapeutic aspects of primary and secondary glomerular disease is reviewed and updated ... of glomerulopathies from both clinical and therapeutic aspects is a welcome addition to our knowledge base An Update on Glomerulopathies - Clinical and Treatment Aspects builds on the background ... fundamental and clinical aspects of glomerular disease has expanded exponentially over the last several decades Fresh insights into old clinico -pathological entities emerge frequently and continuously...
Ngày tải lên: 27/06/2014, 19:20
AN UPDATE ON GLOMERULOPATHIES – CLINICAL AND TREATMENT ASPECTS pdf
... Etiology and Pathogenesis In 24 concise, focused and well-formulated chapters the broad scope of clinical and therapeutic aspects of primary and secondary glomerular disease is reviewed and updated ... of glomerulopathies from both clinical and therapeutic aspects is a welcome addition to our knowledge base An Update on Glomerulopathies - Clinical and Treatment Aspects builds on the background ... fundamental and clinical aspects of glomerular disease has expanded exponentially over the last several decades Fresh insights into old clinico -pathological entities emerge frequently and continuously...
Ngày tải lên: 28/06/2014, 03:20
GLAUCOMA – CURRENT CLINICAL AND RESEARCH ASPECTS pot
... Stephen G Schwartz and Tomomi Higashide Chapter 12 Drops, Drops, and More Drops John Walt and Fern Alexander Chapter 13 Pressure Lowering Medications Liza-Sharmini Ahmad Tajudin and Yaakub Azhany ... examines bench- and animal-modeling research in an attempt to understand the pathogenesis of glaucoma The clinical science section addresses various diagnostic issues and the medical, laser and surgical ... Glaucoma – Current Clinical and Research Aspects in complement activation and inflammatory cytokine/chemokine production, which in turn cause abnormal leukocyte-endothelial interactions and ultimately...
Ngày tải lên: 28/06/2014, 03:20
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