no randomized controlled clinical trials
Báo cáo y học: " A randomized, controlled clinical trial: The effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial" pdf
... A randomized, controlled clinical trial: The effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized ... disorder Methods A three armed randomized, controlled clinical trial including 9-month post-treatment follow-up is proposed Participants screened positive using the Structure Clinical Interview for DSM-IV ... responding for individuals with generalized anxiety Although it has been shown in randomized controlled clinical trials that MBCT can reduce the likelihood of relapse in people with recurrent episodes...
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báo cáo khoa học:"The WRITTEN-HEART study (expressive writing for heart healing): rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac rehabilitation" docx
... in many randomized clinical trials involving individuals with physical disorders such as breast cancer [15-18], rheumatoid arthritis [19], fibromyalgia [20], HIV [21,22], renal cell carcinoma [23], ... rehabilitation program The feasibility, safety and clinical efficacy of such a brief psychological intervention will be evaluated in a four-arm randomized controlled clinical trial with a Page of 12-month ... the evidence-based knowledge on the application of the expressive writing procedure for clinical purposes in clinical settings [52] Author details Istituto Auxologico Italiano IRCCS, Psychology...
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Báo cáo y học: " Using Guasha to treat musculoskeletal pain: A systematic review of controlled clinical trials" pdf
... did not have control (n = 44) or they were part of a complex treatment or concomitant use of other therapies (n = 89) Five randomized controlled trials (RCTs) [5-9] and two controlled clinical trials ... Flowchart of the selection process for the trials RCT: randomized controlled trial CCT: controlled clinical trial UOS: uncontrolled observational study Acknowledgements This research has been supported ... 1.13], NS† Recovery 1.45 [0.77, 2.73], NS n.r.: not reported; NS: no significance; AT: acupuncture; RCT: randomized controlled trial; CCT: controlled clinical trial; VAS: visual analog scale Response...
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Báo cáo y học: "Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial" docx
... was not controlled Recently, Friesecke et al [24] reported that use of a mixed MCT/ LCT/fish oil lipid emulsion in critically ill ICU patients had no effect on inflammatory markers, or on clinical ... pancreatitis: a randomized and controlled study JPEN J Parent Ent Nutr 2008, 32:236-241 26 Gadek JE, DeMichele SJ, Karlstad MD: Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, ... emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial Critical Care 2010, 14:R5 ...
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Báo cáo y học: "Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials." docx
... RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17(1):1-12 23 Stammberger ... Abbreviation: LVRS (Lung volume reduction surgery); RCTs (randomized controlled trials) ; VATS (video-assisted thoracoscopic surgery); MS(median sternotomy); FEV1(forced expiratory volume in one second); ... Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials Wei Huang, 1Wen R...
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Báo cáo y học: "Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility" pptx
... algorithm for designing group sequential clinical trials Biometrics 2001, 57:972-974 Demets DL, Ware JH: Asymmetric group sequential boundaries for monitoring clinical trials Biometrika 1982, 69:661-663 ... Sequential Methods with Applications to Clinical Trials Boca Raton, FL: CRC Press; 2000:171–189 The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network: Higher versus lower positive ... 351:327-336 Anonymous: Randomized, placebo -controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome Crit Care Med 2002, 30:1-6 While there are no...
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Báo cáo y học: "Clinical review: Strict or loose glycemic control in critically ill patients - implementing best available evidence from randomized controlled trials" ppsx
... bars) and strict glycemic control group (open bars) of seven randomized controlled trials Original single-center randomized controlled trials (RCTs) from Leuven [1,2]; single-center RCTs [3,4]; ... control, again SGC was not associated with mortality reduction (15.3% in the intervention group versus 17.2% in the control group) [7] Meta-analyses of randomized controlled trials of strict glycemic ... of the meta-analyses difficult, if not impossible Schultz et al Critical Care 2010, 14:223 http://ccforum.com/content/14/3/223 Page of Table Randomized controlled trials on strict glycemic control...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... therapy [5,6] Currently available medication regimens for most cases include nonopioid analgesics such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) including cyclo-oxygenase ... Walach H, Sadaghiani C, Dehm C, Bierman D The therapeutic effect of clinical trials: understanding placebo response rates in clinical trials: a secondary analysis BMC Med Res Methodol 2005; 5: 26-37 ... http://www.medsci.org Int J Med Sci 2010, novel synergistic composition containing B serrata extract selectively enriched with AKBA and B serrata non-volatile oil The non-volatile oil was prepared using...
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Báo cáo y học: "Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development" docx
... potentially positive Randomized Controlled Trials (RCTs) No good designs Low potential Promising designs Good potential Stop Implement Clinical Trial Program The drug development sequence Note that the ... the ethics of randomized clinical trials Bioethics 1995, 9:127-148 Djulbegovic B: Acknowledgement of uncertainty: a fundamental means to ensure scientific and ethical validity in clinical research ... more fair? Ethics, subject allocation, and randomized clinical trials J Med Ethics 1998, 24:401-408 Chard JA, Lilford RJ: The use of equipoise in clinical trials Soc Sci Med 1998, 47:891-898 Karlawish...
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Báo cáo y học: "Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis" pps
... this approach for the analysis of synovial biopsies from RA patients participating in clinical trials Materials and methods Patients and samples Arthroscopic synovial biopsies were obtained before ... compared with placebo It can be anticipated that there will be an upsurge in randomized controlled trials investigating novel biological agents and small molecules in terms of their safety and efficacy ... most studies but they are not useful in short-term clinical trials [21] The use of magR865 netic resonance images is promising, with acceptable interrater ICC for global synovitis scores and bone...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... immunosuppressive therapies, interstitial lung disease, randomized controlled trials, observational studies, multicenter studies, clinical trials phase II, clinical trials phase III, and clinical ... the randomized clinical trials Comparison of (a) the forced vital capacity (FVC) and (b) the diffusing overall meta-analysis results in the randomized clinical trials capacity for carbon monoxide ... risks for the randomized control trials representing the risk of an adverse event occurring in the CYC group compared with in the non-CYC group Two of the three randomized clinical trials reported...
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Báo cáo y học: " Implementation research design: integrating participatory action research into randomized controlled trials" potx
... how we design interventional trials that are generalizeable, but also have enough flexibility to be meaningful and more likely to be successful locally? To put this another way, how can we marry ... participatory research, but is not identical to these approaches Similarities and differences between PAR and quality improvement strategies While the term 'PAR' is not widely used in clinical circles, many ... dissemination and implementation strategies Health Technol Assess 2004, 8(6):1-72 Oxman AD: No magic bullet: a systematic review of 102 trials of interventions to improve professional practice...
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báo cáo khoa học: " Implementation research design: integrating participatory action research into randomized controlled trials" ppsx
... how we design interventional trials that are generalizeable, but also have enough flexibility to be meaningful and more likely to be successful locally? To put this another way, how can we marry ... participatory research, but is not identical to these approaches Similarities and differences between PAR and quality improvement strategies While the term 'PAR' is not widely used in clinical circles, many ... dissemination and implementation strategies Health Technol Assess 2004, 8(6):1-72 Oxman AD: No magic bullet: a systematic review of 102 trials of interventions to improve professional practice...
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Báo cáo y học: " Maintenance of response with atypical antipsychotics in the treatment of schizophrenia: a post-hoc analysis of 5 double-blind, randomized clinical trials" ppsx
... in large, randomized clinical trials measuring time to discontinuation for any cause [3,28], echoing our results and suggesting that antipsychotic adherence is often driven by efficacy No significant ... both a measure of symptom severity and a time component The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE), a large, randomized, double-blind, 18-month National Institutes of ... were no significant differences in this measure between olanzapine and the risperidone, quetiapine, and aripiprazole groups Discussion In this post-hoc analysis of randomized, double-blind trials...
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Báo cáo y học: " No effect of short-term amino acid supplementation on variables related to skeletal muscle damage in 100 km ultra-runners - a randomized controlled trial" potx
... article as: Knechtle et al.: No effect of short-term amino acid supplementation on variables related to skeletal muscle damage in 100 km ultra-runners - a randomized controlled trial Journal of ... in the amino acid group; and 2,749 (±1,962) %, 168 (±38) %, and 13,435 (±10,724) % in the control group (p < 0.01) The increases were not different between the two groups In the amino acid group, ... finishing time was not correlated to the post race creatine kinase concentration, as has been found in the present study Duration of amino acid supplementation Our athletes ingested the amino acids as...
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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx
... experiments in rodents have provided the basis for human clinical trials In a randomized, double-blind, multicenter, and controlled phase II clinical trial involving 236 patients with severe active ... participation in other clinical trials within months before enrolment Study design The study was a two-to-one, eight-center, 24-week follow-up, double-blind, double-dummy, randomized, and MTX -controlled ... collagen-induced arthritis Immunol Lett 2008, 117:16-25 19 Zhang LL, Wei W, Xiao F, Xu JH, Bao CD, Ni LQ, Li XF: A randomized, double-blind, multicenter, controlled clinical trial of chicken type...
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Báo cáo y học: "High frequency chest wall oscillation for asthma and chronic obstructive pulmonary disease exacerbations: a randomized sham-controlled clinical trial" pptx
... Pneumatic vests worn over the chest, however, may not be acceptable to patients with asthma or COPD with worsening respiratory symptoms To our knowledge, no studies have examined the use of HFCWO in ... physician-diagnosis of acute asthma or COPD at one of four academic medical centers were screened for this study Page of The treating physician was contacted to confirm the clinical diagnosis (acute ... Chicago, Illinois, 60637, USA 6Department of Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 840 S Wood Street, Chicago, Illinois 60612, USA...
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Báo cáo khoa học: "Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia" doc
... trial for another 18 months Double blinded controlled clinical trial over six months Treatment Open clinical trial Follow up18 months Completed no of dogs Drop out Withdrawal Completed no of dogs ... improvement of the clinical signs Acknowledgements The project was supported in part by grant no NFR 123873/320 and NFR 141822/320 by The Research Council of Norway, Dyreidentitet AS and The Norwegian ... implantation if not given previously Placebo Placebo Gold Don't know Gold Yes No 22 12 30 11 35 13 17 Gold bead implantation in dogs with hip dysplasia 63 Table Distribution of 78 dogs in a blinded clinical...
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Báo cáo khoa học: " Randomized controlled trials are needed to determine appropriate blood transfusion strategies in patients with acute coronary syndromes" pdf
... analysis of data from three clinical trials, none of which were designed to address the question of appropriate transfusion thresholds Thus the study is hypothesis generating and not intended to prove ... A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group N ... Vol No Freeman and DeVita Competing interests The authors declare that they have no competing interests References Rao SV, Jollis JG, Harrington RA, Granger CB, Newby LK, Armstrong PW, Moliterno...
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