no bcl 2 family and the control of mitochondrial apoptosis
A park like transformation for the study and the control of a nonsinusoidal brushless DC motor
Ngày tải lên :
03/01/2014, 19:44
... IMPLEMENTATION OF THE NONLMAR FEEDBACK CONTROL SCHEME The implementation of the nonlinear feedback control scheme in "pseudo-dq" frame described above requires numerous control and computation tasks The control ... form of these data, a 24 bit fixed-point DSP (for example the DSP56001) is then sufkient Using this microprocessor, the execution time for the control and computation tasks of the proposed nonlinear ... Vol 29 , No 2, Mar& 1993, pp 20 1 920 23 843 M Zribi, J Chiasson, "Position Control of a PM Stepper Motor by Exad Linearization", Trans on Automatic Control, Vol 36, No 5, May 1991, pp 620 - 625 W...
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Báo cáo y học: "A paragon of self-tolerance: CD25+CD4+ regulatory T cells and the control of immune responses" pps
Ngày tải lên :
09/08/2014, 01:23
... from the Japan Society for the Promotion of Sciences 19 20 References 24 Cohen IR: Regulation of autoimmune disease physiological and therapeutic Immunol Rev 1986, 94:5 -21 Arnold B: Levels of peripheral ... tolerance Transpl Immunol 20 02, 10:109-114 Gershon RK, Kondo K: Cell interactions in the induction of tolerance: the role of thymic lymphocytes Immunology 1970, 18: 723 -737 21 22 Bluestone JA, Abbas ... CD4+CD25+ T regulatory cells Nat Immunol 20 03, 4: 337-3 42 26 Hori S, Nomura T, Sakaguchi S: Control of regulatory T cell development by the transcription factor Foxp3 Science 20 03, 29 9:1057-1061 27 ...
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Drug discovery metformin and the control of diabetes
Ngày tải lên :
12/07/2015, 15:49
... emeritus professor of the history of science at the University of Derby, UK Pete Ellis is professor of psychological medicine at the School of Medicine and Health Sciences, University of Otago, ... from the auto-immune destruction of the cells the UK Many of these problems can be prevented by in the pancreas which produce insulin It occurs most early diagnosis, good blood sugar control and ... 10.1136/bmj.1. 527 9.680) E A Werner and J Bell, J Chem Soc Trans., 1 922 , 121 , 1790 (DOI: 10.1039/CT 922 2101790) C Bailey, Metformin: the gold standard Chichester, UK: Wiley-Blackwell, 20 07 http://en.wikipedia.org/wiki/Metformin...
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Báo cáo khoa học: " AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis" pdf
Ngày tải lên :
09/08/2014, 10:20
... role in the cytotoxic effects of AT-101 Proteins of the Bcl- 2 family mediate mitochondrial permeability and are therefore the key regulators of the intrinsic apoptotic pathways [36] Bcl- 2 proteins ... proteins contain regions of amino acid sequence similarity, known as Bcl2 homology (BH) domains The family consists of the anti-apoptotic Bcl- 2 group (such as Bcl- 2, Bcl- XL, Mcl-1), the pro-apoptotic ... M: BCL- 2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy J Cell Biochem 1996, 60 :23 - 32 Simonian PL, Grillot DA, Nunez G: Bcl- 2 and Bcl- XL...
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Báo cáo khoa học: The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity pot
Ngày tải lên :
22/03/2014, 17:20
... member of the Bcl- 2 family However, unlike in other members of the Bcl- 2 family, the BH3 domain of BNIP3 is not required for its death-inducing activity Our results showing that full-length, but not ... heterodimerizes with Bcl- 2 ⁄ Bcl- X(L) and induces cell death independent of a Bcl- 2 homology (BH3) domain at both mitochondrial and nonmitochondrial sites J Biol Chem 27 5, 1439–1448 Vande Velde C, Cizeau ... members of the Bcl- 2 family, including Bad, Bax, Bid, and Bim, permeabilize mitochondrial membranes [13] Bcl- 2 ⁄ E1B-19K-interacting protein (BNIP3) is a member of a unique subfamily of death-inducing...
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Báo cáo y học: "Coaggregation of Fc RI with Fc RIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells" ppsx
Ngày tải lên :
08/08/2014, 21:20
... protein of the Bcl- 2 family, involved in the regulation of mast-cell apoptosis. 18,19 Another Bcl- 2 family member of crucial importance for Fc⑀RI-mediated activationinduced mast-cell survival is A1 .20 ... Figure 4) Coaggregation of Fc⑀RI with Fc␥RIIB Does Not Affect the Induction of A1 Apoptosis is regulated by members of the Bcl- 2 family A1, one of the antiapoptotic Bcl- 2 family members, is described ... activation of mast cells regulates phosphorylation and expression of forkhead and Bcl- 2 family members Scand J Immunol 20 06;63:1–6 28 Shinjyo T, Kuribara R, Inukai T, et al Downregulation of Bim,...
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Báo cáo khoa học: "The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells" doc
Ngày tải lên :
09/08/2014, 03:21
... member of the Bcl- 2 family, its expression manifests either cytoprotective or cytodestructive phenotypes, depending on the cellular context [21 ] The anti-apoptotic Bcl- 2 family members Bcl- 2 and Bcl- XL ... College, Wenzhou 325 000, China 18 20 21 22 Received: December 20 09 Accepted: 20 April 20 10 Published: 20 April 20 10 23 © 20 10 ZhengofAccess articleBioMed Central Ltd terms of the Creative Commons ... activity of Nur77, thereby facilitating the initiation of apoptosis [31] Whether Bcl- 2 phenotype changes phenomenon occur in arsenic trioxide-induced cell apoptosis is still unknown In the present...
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Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx
Ngày tải lên :
09/08/2014, 10:20
... deleted altogether in the other constructs (B) amino acid sequence of the carboxyterminus of wildtype Bcl- 2, Bcl- 2 ActA, Bcl- 2 cb5 and Bcl- 2 ΔTM The amino acids derived from ActA and cb5 are shown ... of human wildtype Bcl- 2 (Bcl- 2 WT) localizing to both mitochondria and the ER, Bcl- 2 ActA targeted to mitochondria, Bcl- 2 cb5 expressed at the ER, and Bcl- 2 ΔTM localized in the cytosol The Bcl- 2 ... stress and phospholipase A2 Nat Immunol 20 03, 4:387-393 Page of (page number not for citation purposes) Radiation Oncology 20 09, 4:41 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 He...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" ppt
Ngày tải lên :
11/08/2014, 03:20
... isoform (PI3KδD910/A910) but not in PI3Kγ knock-out (PI3Kγ-/-) mice [21 ] Here, the expression of both mSin3a, Mi -2 and Mi -2 remained unchanged in the lungs of smoke-exposed PI3KδD910/A910 and ... (figure 2) Cigarette smoke exposure alters Mi -2 and Mi -2 expression Consistent with the protein expression of mSin3a, the protein expression of Mi -2 was reduced by ~50% in the lungs of smoke-exposed ... Mi -2 , there was no alteration in the either the basal expression or cigarette smoke-mediated reduction in Mi -2 protein in the lungs of PI3Kγ-/- and PI3KD910/A910 mice as compared to wt sham controls...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" pdf
Ngày tải lên :
11/08/2014, 06:22
... isoform (PI3KδD910/A910) but not in PI3Kγ knock-out (PI3Kγ-/-) mice [21 ] Here, the expression of both mSin3a, Mi -2 and Mi -2 remained unchanged in the lungs of smoke-exposed PI3KδD910/A910 and ... (figure 2) Cigarette smoke exposure alters Mi -2 and Mi -2 expression Consistent with the protein expression of mSin3a, the protein expression of Mi -2 was reduced by ~50% in the lungs of smoke-exposed ... Mi -2 , there was no alteration in the either the basal expression or cigarette smoke-mediated reduction in Mi -2 protein in the lungs of PI3Kγ-/- and PI3KD910/A910 mice as compared to wt sham controls...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
Ngày tải lên :
26/10/2012, 10:04
... orally [27 ] Therefore, the aim of the present study was to evaluate the inhibitory effect of some thioglycosides synthesized in our laboratory on human hSGLT1 and hSGLT2 –as a potential therapeutic ... hSGL2 than for hSGLT1, with values of 66.7 ± 3 .2 % and 23 .2 ± 2. 8 %, respectively In contrast, thioglycoside VII had a higher inhibitory effect on hSGLT1 than hSGLT2 with values of 57.9 ± 2. 3% and ... 11 35 12 15 42 10 42 40 52 32 52 88 28 Int J Med Sci 20 07, 135 Figure Effect of thioglycoside I and thioglycoside VII on sodium-dependent AMG uptake on CHO cells expressing hSGLT1 (A) and CHO...
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Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"
Ngày tải lên :
31/10/2012, 16:49
... 1659.4 2. 8 2. 2 2. 2 2. 68 38.6 30.9 36.0 33.8 38.8 34.3 33.1 32. 3 23 .7 10.8 11.53 42. 3 30.6 15.5 36.1 34.3 21 .1 8.5 9.9 38.9 33.8 17.3 32. 7 31.8 22 .8 12. 6 18.4 38.3 29 .3 14.1 20 .2 38.8 24 .7 16.3 ... 24 .1 23 .9 0.81 0.80 1438.6 1939.7 3.1 2. 3 2. 2 2. 7 Poultry Q1 Q5 54.5 49.7 24 .2 23.7 0.81 0.80 1515.3 1833.8 3.7 1.8 2. 0 2. 9 Processed Meat No Yes 54.7 51.3 23 .9 23 .9 0.81 0.81 1617 .2 1659.4 2. 8 ... 29 .7 17.9 22 .1 41.4 23 .7 12. 8 12. 3 35.9 30.7 21 .0 23 .8 39.4 24 .1 12. 7 14.7 37.9 28 .9 18.4 14.6 9.6 15.3 60.5 9.7 0.4 2. 3 28 .6 20 .9 14.7 26 .3 38.0 4.4 0.1 1.4 16.8 11.7 9.8 17.5 61.0 8.3 0.3 2. 7...
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The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products
Ngày tải lên :
25/10/2013, 05:20
... 1 82 Anabolism, 29 AND/ OR logic gates, 21 8 Angiogenesis, 25 6 Antagonistic, 21 3 Anthocyanidins, 29 7 Anthocyanins, 23 2, 383 Anti-sense gene, 11, 24 , 25 , 26 27 , 29 technology, 11 Apoplast, 53 Apoptosis, ... 22 4 F FAME, 188 Farm chemurgy movement, 175 Feedback regulation, 27 28 Flavanols, 23 2, 29 7 Flavanones, 29 7 Flavodoxin (Fld), 65, 78– 82 Flavones, 29 7 Flavonoid compounds, 383 Flavonoids, 23 , 23 2, ... 21 8, 21 9 Loewe additivity, 22 0 Loewe index, 22 2 M Maize, 29 , 41, 42, 45, 74, 168, 169, 1 82, 196, 29 8, 311, 333, 334, 335, 3 42, 374, 376 Materials and methods (biofumigants), 391–394 Meal, 112...
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Alternative Processing Technologies for the Control of Spoilage Bacteria in Fruit Juices and Beverages
Ngày tải lên :
25/10/2013, 21:20
... identify and review the kinetics and use of nonthermal alternative processes.31 Most notably, as a part of the Þve-year contract between the Institute of Food Technologists (IFT) and the FDA, ... Apple Apple Tomato 2. 9 2. 3 1 2 2–4 Apple 2. 4 2. 5 Apple 2. 5 3–4 Nonpathogenic Bacteria Hydrogen peroxide (H2O2) (50–60ûC) Hydrogen peroxide (H2O2) + acidic surfactants (50–60ûC) © 20 03 by CRC Press ... 90% of their energy at a wavelength of 25 3.7 nanometers Exposure of bacteria to UV results in cross-linking of the thymine dimers of the DNA in the organism, preventing repair of injury and reproduction...
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Intrathecal baclofen for the control of spinal and supraspinal spasticity
Ngày tải lên :
01/11/2013, 10:20
... with their therapists rather than their doctors The charting of range and function before and after a trial dose of ITB is usually done by a therapist The charts concerned are not standardized; they ... cord than in the brain because of the characteristics of the circulation of the CSF from the ventricles to the spinal subarachnoid space The effective distribution volume of intrathecally administered ... Intrathecal baclofen for the control of spinal and supraspinal spasticity Figure 10 .2 A programmable pump, and spinal catheter with centimetre length markings The refill port is at the centre of the pump...
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Tài liệu Golf and the game of leadership 2 pdf
Ngày tải lên :
24/12/2013, 16:15
... require understanding and consistent practice of basic fundamentals Both demand, for most of us, the necessity of practice Tools are 10589$ $TEE 02- 23-04 16:44:07 PS Golf and the Game of Leadership ... accomplished But the job now is ‘ the leadership of others’’ in the context of the organization’s vision, values, and strategy Therefore, my focus throughout this book is on you We’ll look at the attitudes, ... 02- 23-04 16:44:07 PS Golf and the Game of Leadership I facilitate a leadership development program for technical people The participants are mostly engineers At the beginning of the first day of...
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Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc
Ngày tải lên :
13/02/2014, 10:20
... exfoliation203 and a major study in high risk women204 and a meta-analysis205 does not show any protection against STDs Given the effects on the genital epithelium the use of nonoxynol-9 cannot be ... condoms of normal thickness201 The use of microbicides such as nonoxynol-9 can cause a significant increase in genital symptoms and epithelial disruption ,20 7, 20 2 may cause rapid rectal epithelial ... level of burden and the nature of concern are often altered by the HIV status of the child; Goldstein151 noted that approximately 20 % of HIV positive parents in the USA had parenting concerns (no...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
Ngày tải lên :
14/02/2014, 18:20
... Journal 27 8 (20 11) 20 01 20 10 ª 20 11 The Authors Journal compilation ª 20 11 FEBS 20 07 TEC kinases and disease 21 22 23 24 25 26 27 28 29 30 31 A Hussain et al Campana D (20 09) Primary B cell immunodeficiencies: ... thereby providing the missing data The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has been described previously in detail [26 ,27 ], ... catalysis of the Tec family kinases Biochemistry 46, 5455–54 62 FEBS Journal 27 8 (20 11) 20 01 20 10 ª 20 11 The Authors Journal compilation ª 20 11 FEBS A Hussain et al 44 Guo S, Wahl MI & Witte ON (20 06)...
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Tài liệu Social and Economic Control of Alcohol The 21st Amendment in the 21st Century docx
Ngày tải lên :
15/02/2014, 19:20
... HV5085.J87 20 08 3 62. 2 92 609973‑‑dc 22 2007018 725 Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com AU5463.indb 10/9/07 11:11 :21 ... direct failure of federal intervention How does a free enterprise system control the normal economics of supply and demand? To this, one must alter the dynamics of the normative economic model wherein ... 20 What We Know about the Demand for Alcohol 21 Price Elasticity 21 Differences by Group 22 The Effects of Taxation 23 Goals of Taxation .23 ...
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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
Ngày tải lên :
19/02/2014, 05:20
... Journal 27 3 (20 06) 528 8–53 02 ª 20 06 The Authors Journal compilation ª 20 06 FEBS 529 9 Palmitoyl-CoA and control of mitochondrial function J Ciapaite et al The response of the flux Jk to the change ... compilation ª 20 06 FEBS 529 5 Palmitoyl-CoA and control of mitochondrial function J Ciapaite et al ANT contributed only 29 % of the overall increase in the QH2 ⁄ Q ratio, most of the rest of the increase ... control exerted by the proton leak Similarly to the control of the ATPin ⁄ ADPin ratio, the distribution of the control of the ATPout ⁄ ADPout ratio within the respiratory chain depended on the...
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