nitric oxide and inducible nitric oxide synthase

... pterin-free inducible nitric- oxide synthase J Biol Chem 276, 421–427 Gorren AC, Schmidt K & Mayer B (2002) Binding of l-arginine and imidazole suggests heterogeneity of rat brain neuronal nitric oxide synthase ... P450 and nitric oxide synthase Drug Metab Rev 34, 479–501 16 Sennequier N & Stuehr DJ (1996) Analysis of substrate-induced electronic, catalytic, and structural changes in inducible NO synthase ... neuronal nitric oxide synthase in Escherichia coli Proc Natl Acad Sci USA 92, 8428–8432 Chen PF, Tsai AL, Berka V & Wu KK (1996) Endothelial nitric- oxide synthase Evidence for bidomain structure and...

Ngày tải lên: 16/03/2014, 22:20

... expression of inducible nitric oxide synthase Biol Chem 384, 1343–1364 10 Kleinert H, Pautz A, Linker K & Schwarz PM (2004) Regulation of the expression of inducible nitric oxide synthase Eur ... effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production Inflamm Res 49, 20–26 Lu SC, Chang SF, ... protein kinases and phosphoinositide 3-kinase (PI3K), downstream of the TLR4-signaling pathway [3–5] Of the LPS-induced genes, those coding for inducible nitric oxide synthase (iNOS) and granulocyte-colony...

Ngày tải lên: 22/03/2014, 17:20

... Troso, T and Nathan, C Cloning and characterization of inducible nitric oxide synthase from mouse macrophages Science 1992, 256(5051), 225-228 Xie, Q W and Nathan, C The high-output nitric oxide ... W and Brosnan, C F Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomelitis 27 28 29 30 31 32 33 34 35 36 37 38 Induction of nitric oxide ... the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis Eur J Immunol 1998, 28(4), 1332-1338 Sarih, M., Souvannavong, V and Adam, A Nitric oxide synthase...

Ngày tải lên: 07/08/2014, 14:22

... H., Fatzer, R., Vandevelde, M and Zurbriggen, A Comparison of inducible nitric oxide synthase expression in the brain of Listeria monocytogenes-infected cattle, sheep and goats and in macrophages ... D.J., Minc-Golomb, D and Schwartz, J.P Synthesis of nitric oxide in CNS glial cells T.I.N.S 1993, 16, 323-328 13 Nathan, C and Xie, Q.-W Nitric oxide synthases: Roles, tolls and controls Cell 1994, ... Matsumoto, Y and Shin, T Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis J Vet Sci., 2000, 1, 11-17 11 Moncada, S., Palmer, R.M.J and Higgs,...

Ngày tải lên: 07/08/2014, 14:23

... Peterhans E, Jungi TW: Inducible nitric oxide synthase in cattle Differrential cytokine 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 regulation of nitric oxide synthase in bovine and murine macrophages ... nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes J Immunol 1998, 161:467-473 Alwan WH, Dieppe PA, Elson CJ, Bradfield JW: Hydroxyapatite and ... human inducible nitric oxide synthase (iNOS) gene Shock 2000, 13:413-424 70 Marks-Konczalik J, Chu SC, Moss J: Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase...

Ngày tải lên: 09/08/2014, 06:23

... protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes J Immunol 1998, 161:467-473 25 Meyer M, Schreck R, Bauerle PA: H2O2 and antioxidants ... Pillinger MH, Abramson SB: Nitric oxide synthases and osteoarthritis Curr Rheumatol Rep 2007, 9:9-15 Weinberg JB, Fermor B, Guilak F: NOS and COX interactions in cartilage and meniscus: relationships ... mechano-sensitive and cytokine-sensitive pathways, and determines the effects of IL-1β and dynamic compression on the expression levels of iNOS and COX-2 and involvement of the p38 MAPK pathway Materials and...

Ngày tải lên: 09/08/2014, 10:23

... Signal 2001, 13:85-94 Goodwin DC, Landino LM, Marnett LJ: Effects of nitric oxide and nitric oxide- derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis FASEB J 1999, ... of prostaglandin biosynthesis by nitric oxide and nitric oxide donors Pharmacol Rev 2005, 57:217-252 13 Vassalle C, Domenici C, Lubrano V, L’Abbate A: Interaction between nitric oxide and cyclooxygenase ... P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R: Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial...

Ngày tải lên: 10/08/2014, 05:21

... cystitis Urology 2009, 73:421-426 Linares-Fernandez BE, Alfieri AB: Cyclophosphamide induced cystitis: role of nitric oxide synthase, cyclooxygenase-1 and 2, and NK(1) receptors J Urol 2007, 177:1531-1536 ... Figure Urine levels of active and latent/total TGF-β1 at baseline and after CYP Urine levels of active and latent/total TGF-β1 at baseline and after CYP Active and latent/total TGF-β1 values ... contributions PT and YV designed the study DB, PL, VT and EW executed the experiments in the manuscripts NY and RZ were involved in data analysis and manuscript preparation All authors read and approved...

Ngày tải lên: 11/08/2014, 08:22

... HA: hyaluronan; HIF-1α: hypoxiainducible factor-1-alpha; iNOS: inducible nitric oxide synthase; MMP: matrix metalloproteinase; NO: nitric oxide; NOS: nitric oxide synthases; No-tr: no treatment; ... sections from No-tr (a) and SA (b) animals Administration of HA (c) to adjuvant-induced rat produced a marked reduction in the immunostaining for inducible nitric oxide synthase Quantitative analysis ... doses; 3D6d, follow-up at the 6th day after three doses; HIF-1a, hypoxia -inducible factor-1-alpha; iNOS, inducible nitric oxide synthase; MMP3, matrix metalloproteinase-3 consistent with the results...

Ngày tải lên: 12/08/2014, 17:21

... P: Inducible nitric oxide synthase- deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia FASEB J 1997, 11:955-964 28 Hickey MJ, Granger DN, Kubes P: Inducible nitric oxide ... microvascular leakage with induction of nitric oxide synthase: effects of nitric oxide synthase inhibitors in various organs Eur J Pharmacol 1995, 283:47-53 33 Brutsaert DL, Andries LJ: The endocardial endothelium ... endotoxemia and human septic shock Crit Care Med 1995, 23:253-258 Liu SF, Barnes PJ, Evans TW: Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase...

Ngày tải lên: 13/08/2014, 10:20

... 88 89 90 91 92 93 transfer between the two flavins in the human neuronal nitric- oxide synthase and inducible nitric- oxide synthase flavin domains J Biol Chem 278, 30859–30868 Guan ZW & Iyanagi T ... neuronal nitric- oxide synthase J Biol Chem 275, 5052–5058 Roman LJ, Miller RT, de La Garza MA, Kim JJ & Masters BSS (2000) The C-terminus of mouse macrophage inducible nitric- oxide synthase attenuates ... mammalian nitric- oxide synthases J Biol Chem 279, 36876–36883 Abu-Soud HM, Yoho LL & Stuehr DJ (1994) Calmodulin controls neuronal nitric- oxide synthase by a dual mechanism Activation of intra- and...

Ngày tải lên: 18/02/2014, 11:20

... (1993) Macrophage Nitric Oxide Synthase Subunits J Biol Chem 268, 21120–21129 15 Albakri QA & Stuehr DJ (1996) Intracellular assembly of inducible NO synthase is limited by nitric oxidemediated changes ... induces nitric oxide synthase in human neutrophils J Clin Invest 99, 110–116 Daniliuc S, Bitterman H, Rahat MA, Kinarty A, Rosenzweig D & Nitza L (2003) Hypoxia inactivates inducible nitric oxide synthase ... Darling KE, Picot J & Evans TJ (2002) Epithelial inducible nitric oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output J Biol Chem 277, 33132–33138 14 Baek...

Ngày tải lên: 19/02/2014, 16:20

... relaxing factor and the chemical reactivity of nitric oxide J Exp Med 169, 1011–1020 Abu-Soud HM & Stuehr DJ (1993) Electron transfer in the nitric- oxide synthases Nitric oxide synthases reveal ... purview and parameters Nat Rev Mol Cell Biol 6, 150–166 Lancaster J (1997) A tutorial on the diffusibility and reactivity of free nitric oxide Nitric Oxide 1, 18–30 Salerno JC (2008) Neuronal nitric ... tetrahydrobiopterin radical within nitric- oxide synthase J Biol Chem 283, 11734–11742 35 Crane BR et al (1998) Structure of nitric oxide synthase oxygenase dimer with pterin and substrate Science 279,...

Ngày tải lên: 07/03/2014, 00:20

... (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 ´ Roman LJ, Martasek P & Masters BS (2002) Intrinsic and extrinsic modulation of nitric oxide synthase ... sites of calmodulin and electron transfer by neuronal nitric oxide synthase Biochemistry 36, 12337–12345 11 Ghosh DK & Salerno JC (2003) Nitric oxide synthases: domain structure and alignment in ... calmodulin and electron transfer by inducible nitric oxide synthase Biochemistry 44, 7593–7601 29 Newton DC, Montgomery HJ & Guillemette JG (1998) The reductase domain of the human inducible nitric oxide...

Ngày tải lên: 16/03/2014, 13:20

... Ubiquitination of inducible nitric oxide synthase is required for its degradation Proc Natl Acad Sci USA 99, 12315–12320 15 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated ... apo-neuronal nitric- oxide synthase J Biol Chem 277, 20504–20509 11 Dunbar AY, Kamada Y, Jenkins GJ, Lowe ER, Billecke SS & Osawa Y (2004) Ubiquitination and degradation of neuronal nitric- oxide synthase ... cleavage of inducible nitric oxide synthase (iNOS) by calpain I Biochim Biophys Acta 1568, 216– 224 23 Su Y & Block ER (2000) Role of calpain in hypoxic inhibition of nitric oxide synthase activity...

Ngày tải lên: 30/03/2014, 04:20

... neuronal nitric- oxide synthase distinct polypeptides – identification heme-binding proximal thiolate ligand cysteine-415 Biochemistry 34, 3686–3693 13 Abu-Soud, H & Stuehr, D (1993) Nitric oxide synthases ... endothelial nitric oxide synthase; iNOS, rat inducible nitric oxide synthase; CPR, human cytochrome P450 reductase; NR1, human novel oxidoreductase 1; MSR, human methionine synthase reductase; BM3, ... relaxing factor produced and released from artery and vein is nitric oxide Proc Natl Acad Sci USA 84, 9265–9269 Palmer, R.M., Ferrige, A.G & Moncada, S (1987) Nitric oxide release accounts for...

Ngày tải lên: 30/03/2014, 14:20

Ngày tải lên: 07/08/2014, 15:20

... PD-020 an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage ... The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for an inducible "neuronal-like" nitric oxide synthase J Exp Med 1995, 182:2097-2102 ... Kohsaka H, Liu M, Higashiyama H, Hirata Y, Kanno K, Saito I, Miyasaka N: Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides J Clin Invest 1995, 96:2357-2363...

Ngày tải lên: 09/08/2014, 14:20

... hypoxia and altered hemodynamics on endothelial nitric oxide synthase expression in the adult rat lung J Clin Invest 1998, 101(4):795-801 Xue C, Johns RA: Upregulation of nitric oxide synthase ... diaphragmatic hernia and pulmonary hypoplasia of other causes Pediatr Dev Pathol 2004, 7(5):468-477 Solari V, Piotrowska AP, Puri P: Expression of heme oxygenase1 and endothelial nitric oxide synthase in ... William M, McPhaden AR, Stannigel H, Mayatepek E, Wadsworth RM: Endothelial, inducible and neuronal nitric oxide synthase in congenital pulmonary lymphangiectasis Eur Respir J 2006, 27(6):1311-1315...

Ngày tải lên: 12/08/2014, 14:20

... rat and hamster lungs: role of inducible nitric oxide synthase Toxicol Appl Pharmacol 2002, 181:93-105 Dorger M, Allmeling AM, Kiefmann R, Schropp A, Krombach F: Dual role of inducible nitric oxide ... characterization of nitric oxide synthase isoforms reveals striking active-site conservation Nat Struct Biol 1999, 6:233-242 Schulz C, Gillissen A, Schultze-Werninghaus G: Inducible nitric oxide synthase ... 21:589-597 al-Ali MK, Howarth PH: Nitric oxide and the respiratory system in health and disease Respir Med 1998, 92:701-715 Kerwin JF Jr, Lancaster JR Jr, Feldman PL: Nitric oxide: a new paradigm for...

Ngày tải lên: 12/08/2014, 18:21