neural behavioral and psychological effects of injury in athletes

CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model

CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model

... by the institutional IRB of Jichi Medical University (Rin A17–164) and conducted in accordance with the guiding principles of the Declaration of Helsinki Written informed consent was obtained from ... min) – 0% (2.0 min) – 25% (5.0 min) – 35% (11 min) – 95% (15 min) – 95% (20 min) – 0% (20.1 min) Nitrogen gas was used as the nebulizer gas with drying gases at flow rates of 3.0 and 10 L/min, ... antiCD39 and APC-conjugated anti-CD73 mAb for 30 at a final concentration of 2.5 μg/mL After washing twice with staining buffer, the cells were incubated with 7-AAD for 15 on ice and staining intensity

Ngày tải lên: 30/05/2020, 21:32

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The Academic and Psychological Effects of Teaching Students with

The Academic and Psychological Effects of Teaching Students with

... the sequence? ?of? ?events or analyzing characters. The general approach to reading? ?and? ? comprehending an article, though, ends up being taken from my hands? ?and? ?being put into  the hands? ?of? ?the students. Suddenly, I find myself a step behind? ?in? ?my own classroom. By  ... classrooms over longer periods? ?of? ?time. I would recommend establishing the routine? ?of? ? using CSI? ?and? ?reflecting? ?in? ?the first month? ?of? ?the school year? ?and? ?maintaining the study  through the end? ?of? ?the year. I would also recommend that this study be implemented? ?in? ?at  ... practice. Anecdotally, though, I see a remarkable confidence shift over the year? ?in? ?the  students? ?and? ?knowing how we read an article. Oftentimes,? ?in? ?the beginning? ?of? ?the school  year, I need to help guide students? ?in? ?being able? ?and? ?willing to share their thoughts about 

Ngày tải lên: 30/10/2022, 16:39

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Báo cáo lâm nghiệp: "Carbon pool and substitution effects of an increased use of wood in buildings in Switzerland: first estimates" pdf

Báo cáo lâm nghiệp: "Carbon pool and substitution effects of an increased use of wood in buildings in Switzerland: first estimates" pdf

... emissions of around 18% of the total effect of an increased use of wood in Switzerland If one considers the effect of an increased use of wood in the mirror of the reduction commitment in absolute ... overestimated and might in fact be rather low This effect is linked to a far larger decrease of the standing volume of trees (and thus carbon) in the forests and of soil carbon because of the harvesting, ... Switzerland Thus, the GHG effects of an increased use of wood within Switzerland are of particular interest The contributions of the different GHG-relevant mechanisms of an increased use of wood over time

Ngày tải lên: 08/08/2014, 00:22

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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

... grants -in- aid from the Ministry of Health, Labor and Welfare, and the Ministry of Education, Science, Sports and Culture, Japan, and the Japanese Ministry of Education, Global Center of Excellence ... for 30 minutes 3H-thymidine was added and B cells were incubated for 24 hours The incorporated radioactivity was quantified Fold increase in 3H-thymidine incorporation in response to chemokine stimulation ... analysis, interpretation, and manuscript preparation KT and YK participated in the data analysis and interpretation, and assisted in manuscript preparation TM, HK, AN, PEL, and NM assisted in data interpretation

Ngày tải lên: 09/08/2014, 14:22

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Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot

Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot

... conditions in the host, including persistence [2-4]. In the face of increasing resistance against antibiotics as well as persis- tence of staphylococci in the patient, an intensive search of new ... A new emerging paradigm for investigating drug effects and toxicity is followed here: instead of consider- ing the body of the studied organism as a black box and * Correspondence: dandekar@biozentrum.uni-wuerzburg.de ... encoding proteins involved in the transport of macromolecules, such as the ATP-bind- ing cassette (ABC) transporter, the peptide transporter, and the choline transporter, and metabolic enzymes of

Ngày tải lên: 09/08/2014, 22:24

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báo cáo khoa học: " Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand" doc

báo cáo khoa học: " Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand" doc

... jaw, and an inability to urinate. Others mentioned less often included impaired sexual perform- ance, dizziness, sore eyes, stomach pains, teeth grinding, increased rates of smoking, and bleeding ... suppose, drinking at home, having a few drinks at home then going to town and then taking the party pills when you get there. Or maybe having a party at home or something, drinking alcohol and then ... behaviour (note: this information is often contained on BZP-party pill packaging). Drinking often took place prior to taking the substances, as a part of general socialising or in the 'warm-

Ngày tải lên: 11/08/2014, 18:20

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Báo cáo y học: " The characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern" ppsx

Báo cáo y học: " The characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern" ppsx

... characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern Ming-ren Ma, Xiao-qin Ha*, Hui Ling, Mei-liang Wang, Fang-xin Zhang, Shang-di ... and has a compact and circular DNA genome of about 3.2kb in length, with four overlapping open reading frames including large S region (PreS/S), PreC/C, X and P [2, 3] Moreover, the overlapping ... evolution of HBV should be interactional and constrained by the overlap of genes [4] In some cases, the evolution of one overlapping-gene protein may evolve more rapidly as a consequce of negative

Ngày tải lên: 11/08/2014, 21:22

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Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx

Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx

... Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor ... compensations and hypersensitivities in a rat model lumbar radiculopathy. Behavioral changes observed in pre-clinical models of lumbar radicular pain may relate to painful symptoms observed in human ... development of limb dysfunction and gait compensations following lumbar radiculopathy in the rat. In this study, we expand upon the description of gait compensations following lumbar radiculopathy in

Ngày tải lên: 12/08/2014, 17:22

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Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc

Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc

... inflammation In individuals with pre-existing lung disease, inhalation of nanoparticles may induce inflammation and exacerbate respiratory and cardiovascular effects through the induction of oxidative ... contained in 6-well plates Cells were seeded in RPMI medium containing 0.1% BSA and penicillin/streptomycin at a density of × 105 cells/ ml and incubated at 37°C, 5% CO2 for hour before washing ... cortical staining In accord with the role of calcium and ROS in the induction of IL-1 expression, both of these factors appeared to play an important role in modulating the F-actin cytoskeleton

Ngày tải lên: 12/08/2014, 18:21

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Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc

Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc

... in U1 and ACH-2 cells, and toxicity in uninfected Jur-kat T-cellsFigure 1 Potencies of different HDACIs in terms of activation of HIV-1 replication in U1 and ACH-2 cells, and toxicity in uninfected ... protein (GFP)- encoding gene under control of the HIV-1 LTR [17]. In these Jurkat cell clones, GFP induction by HDACIs was evident only in a fraction of cells at 24 hours of incubation and increased ... towards increased HAT activity and DNA unwinding, thus facilitating the binding of several transcription factors [27]. The HIV-1-induced pro-oxidant status is in part mediated by decreased intracellular

Ngày tải lên: 12/08/2014, 23:21

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Báo cáo khoa học: "The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass graftin" pdf

Báo cáo khoa học: "The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass graftin" pdf

... calculations and were involved in drafting the manuscript. SK, MB, and LB participated in coordinating the study and in the interpretation of data and were involved in drafting the manuscript. JP was involved ... were given. Standard postoperative care included targeting of blood glucose levels of less than 200 mg/dl by continuous infusions of insulin and targeting of hemo- globin levels of greater than ... normalization of the urinary excretion of alpha-1-microglobulin and an increase in plasma levels of cystatin-C, suggesting that adrenaline aggravates perioperative tubular injury and leads to

Ngày tải lên: 13/08/2014, 03:21

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Báo cáo y học: "Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study" potx

Báo cáo y học: "Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study" potx

... following interventions, defined as events: sedative and analgesic drug bolus, increasing or decreasing continuous sedation and analgesia, intratracheal suctioning, and other potentially painful interventions ... course of RE and BIS-Index during endotracheal suctioning episodes (a) Time course of RE during the endotracheal suctioning episodes (ET), RE and BIS-Index during endotracheal suctioning episodes ... approved, but not influenced, by GE Healthcare Instrumentarium/Datex-Ohmeda was not involved in any way in collection, analysis and interpretation of data, in writing of the manuscript, or in the decision

Ngày tải lên: 13/08/2014, 11:22

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Báo cáo y học: "Relative effectiveness and adverse effects of cervical manipulation, mobilisation and the activator instrument in patients with sub-acute non-specific neck pain: results from a stopped " ppt

Báo cáo y học: "Relative effectiveness and adverse effects of cervical manipulation, mobilisation and the activator instrument in patients with sub-acute non-specific neck pain: results from a stopped " ppt

... follow up point. Pain decreased by 3 points in the Activator group, 4 points in the manipulation group, and 3 points in the mobilisation group. A reduction in pain of at least 2 points is considered ... manipulation is a passive and rapid movement of a joint beyond its active and passive limit of movement, but remaining within the limit of the joint's anatomical integ- rity. Participants ... manipulation and four with mobilisation. All instances of side effects were minor and resolved within 1-3 days. Table 7 shows the type and number of adverse effects reported by each group. Use of rescue

Ngày tải lên: 13/08/2014, 14:20

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GENOME-DESTABILIZING AND MUTAGENIC EFFECTS OF BREAK-INDUCED REPLICATION IN SACCHAROMYCES CEREVISIAE

GENOME-DESTABILIZING AND MUTAGENIC EFFECTS OF BREAK-INDUCED REPLICATION IN SACCHAROMYCES CEREVISIAE

... phosphoinositol-3-kinase-related kinase RDR Recombination-dependent replication RNR Ribonucleotide reductase SDSA Synthesis-dependent strand annealing SSA Single-strand annealing ssDNA Single-stranded ... Genome-destabilizing and Mutagenic Effects of Break-induced Replication in Saccharomyces cerevisiae Major Professor: Cynthia... cutting of the flap, especially when the direct repeats being ... replication in an... 12 2.2.3 Single-strand Annealing Single-strand annealing (SSA) is an efficient repair pathway that repairs a DSB by annealing of complementary sequences on either side of the

Ngày tải lên: 24/08/2014, 11:07

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epidemiological characteristics of asthma in 13-14-year-old children and the effects of health education intervention in two districts of hanoi

epidemiological characteristics of asthma in 13-14-year-old children and the effects of health education intervention in two districts of hanoi

... MINISTRY OF EDUCATION AND TRAINING MINISTRY OF HEALTH THE NATIONAL INSTITUTE OF HYGIENE AND EPIDEMIOLOGY *** ĐANG HUONG GIANG EPIDEMIOLOGICAL CHARACTERISTICS OF ... knowledge of parents on asthma was impaired. Studying epidemiological characteristics of asthma and carrying out the interventions in communities to manage asthma and to improve quality of life of ... 0.5%. In some countries such as Switzerland, Portugal and Japan the reduction in asthma mortality have appeared by increasing use of inhaled corticoides 1.1.2 Epidemiology of asthma in Viet

Ngày tải lên: 04/12/2014, 03:48

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In vitro and in vivo studies into the antidiabetic and antilipidemic effects of chlorogenic acid

In vitro and in vivo studies into the antidiabetic and antilipidemic effects of chlorogenic acid

... Activation of insulin signaling upon binding of insulin to insulin receptors causes suppression of gluconeogenesis in liver and. .. catechoamines are released and they inhibit insulin secretion ... secreted by intestine in response to nutrients ingestion Their main effect is to stimulate pancreas to release insulin after meals intake 6 Two incretin... Activation of insulin signaling is an ... Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: Identification of biomarkers of coffee consumption. Drug Metabolism and Disposition

Ngày tải lên: 08/09/2015, 18:22

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ANTI CANCER EFFECTS OF THYMOQUINONE IN BREAST CANCER CELLS INVOLVEMENT OF NON HOMOLOGOUS END JOINING AND TELOMERE TELOMERASE HOMEOSTASIS

ANTI CANCER EFFECTS OF THYMOQUINONE IN BREAST CANCER CELLS INVOLVEMENT OF NON HOMOLOGOUS END JOINING AND TELOMERE TELOMERASE HOMEOSTASIS

... deficiencies in cell cycle checkpoint function in breast cancer cells 41 3.1.3 Changes in cell cycle protein expressions in TQ-treated breast cancer cells 44 3.2 DNA damaging effects of TQ in normal and ... anti-neoplastic effects of thymoquinone (TQ), a main active constituent of Nigella Sativa seeds, had been demonstrated in various in vitro and in vivo cancer models with minimal toxicity in normal ... performing dual immunofluorescence staining studies involving the co-localisation of DNA-PKcs with telomere specific probes Studies have validated the promising results of combinatorial therapy by inhibition

Ngày tải lên: 30/09/2015, 13:41

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investigating direct and indirect effects of variables in marketing

investigating direct and indirect effects of variables in marketing

... implications of such a representation of brand information in memory are studied in two experiments This thesis is geared toward understanding and developing models for measuring direct and indirect effects ... effects of brand beliefs and media on purchase intent and indirect effects through auxiliary multivariate regressions Our approach thus identifies direct and indirect effects of media and brand ... underlying finding in all the essays is: not accounting for indirect effects of variables can mask the true impact and underestimate the effects of commonly encountered variables in marketing The...

Ngày tải lên: 02/11/2014, 00:42

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Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

... phosphorylation of subunit proteins Increases in glutamate after injury trigger VGCC and NMDA receptors, increasing [Ca2+]i, and resulting in activation of CaMKII A single dose of DZ can downregulate ... function of the GABAAR Increases in α1 mRNA and protein expression during development correspond to increases in BZ binding and altered zinc sensitivity [54], while reduced α1 mRNA and protein expression ... the injuryinduced decrease in expression (M = 74.93) [F(3,9) = 14.907, p < 01], indicating DZ decreased α3 expression, regardless of injury condition DZ normalized γ2 injuryinduced decreases in...

Ngày tải lên: 10/08/2014, 05:21

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Tài liệu Gulf War and Health: Volume 4. Health Effects of Serving in the Gulf War docx

Tài liệu Gulf War and Health: Volume 4. Health Effects of Serving in the Gulf War docx

... of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers It is autonomous in its administration and in ... principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering ... weapons in fighting Iran and in attacks on the Kurdish minority in Iraq Military leaders feared that the use of such weapons in the gulf could result in the deaths of tens of thousands of Americans...

Ngày tải lên: 16/02/2014, 01:20

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