... guidelines forthe screening and selection of patients for Page of 10 APBI [22,23], and these guidelines formed the basis for patient selection in the EBT multicenter study [20] Ofthe 65 patients ... of 1.8 was tabulated The mean score was 1.5 forthe 20 patients who received local anesthesia, forthe patient administered sedation, and 2.1 forthe 18 patients who received both local anesthesia ... maintain the distance from the balloon to the skin surface The greater the volume ofthe balloon, with the attendant compression of adjacent breast tissue, the more fully the target breast tissue...
... of data, interpretation ofthe data, and revision ofthe article for content SZ contributed to the conception and design ofthe work, interpretation ofthe data, and revision ofthe article for ... sampling of data, interpretation ofthe data, and drafting ofthe article JK contributed to the conception ofthe work, interpretation ofthe data, revision ofthe article for content, and approval of ... of rFVIIa compared with placebo The mean estimated risk of thromboembolism of 6.42% in the eight studies on the prophylaxis of bleeding was within the 95% CI of 1.2% to 31.8% determined for the...
... 100% relief of their pain in 86% ofthe patients with a median relief period of months The range of relief varied from zero days to up to 13 months forthe facet injection group None ofthe lumbar ... median period of pain relief being months The range of relief forthe radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Ofthe 14 patients ... improvement from the radiofrequency procedure, the length of improvement varied from months to 16 months Again, no one in the radiofrequency group developed permanent relief of their pain Thus, the endoscopic...
... follow-up Results The author acknowledges that there are no conflicts of interest or financial benefits with the results ofthe study All twelve patients (10 males, females) completed thesurgery without ... increases the risk of adverse events with invasive approaches Open surgical correction is the current standard of care for foraminal stenosis of cervical and lumbar vertebrae Open surgery requires ... laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the current...
... ethanol at a final concentration of 10%, then transported to the laboratory of UT at 4oCstored Then, each ofthe samples were divided into two One of them was for DNA extraction and was washed ... general, the higher concentration of primers can lead to the formation of primer dimers Also, the cost ofthe chemicals should be minimized if the same quantitativeness can be achieved The results ... Another was for FISH analysis and was stored at -80oC The extraction of DNA was performed with Fast DNA SPIN Kit for Soil (Qbuiogene, USA) according to the instruction by the manufacturer In the...
... with the increased HRT ofthe adsorption tank From an engineering application point of view, the appropriate operational parameters ofthe recycle ratio, HRT ofthe regeneration tank, HRT ofthe ... in the PO43 P removal These results revealed that the selection ofthe operational parameters ofthe CARS process had a great influence on the overall system performance Adsorptive capability of ... technical feasibility of this process was demonstrated The effects of recycle ratio, HRT ofthe regeneration tank, HRT ofthe adsorption tank and SRT ofthe system were evaluated The removal efficiency...
... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival ofthe patients in the cetuximab monotherapy arm ofthe RCT The data from the monotherapy arm NICE ... from the perspective ofthe NHS Unlike the manufacturer’s models the outcome data were based on published overall survival curves from the two studies The utility value for pre-progression was the ... negligible if further active treatment was not available Therefore the results seen in the single-arm cetuximab studies for these outcomes could be interpreted as an effect ofthe drug It also...
... reported on the efficacy and/or effectiveness of hydroxyurea treatmentof hematologic diseases, the toxicity of hydroxyurea in thetreatmentof any disease, and the barriers to thetreatmentof sickle ... reviewer reconciled the results ofthe first two reviewers in the case ofthe randomized trials 29 Forthe other study designs, the results ofthe two reviewers were averaged The quality assessment ... reliability ofthe instruments used A pair of reviewers each performed the quality assessment independently In the case ofthe RCTs, a third reviewer reconciled the results ofthe first two reviewers; for...
... (COX) In these enzymes, the redox potential ofthe metals is harnessed to provide the enzymes with their electron transfer capabilities Paradoxically, it is the same redox potential ofthe metals ... that the interaction between Ab and these metals can promote the formation of Ab oligomers, aggregates and fibrils [48,52–55] Metal mediated oligomerization of Ab may therefore contribute to the ... within the physiological ranges that could be expected within the brain The capacity for metals to facilitate this process may therefore be a critical factor in the Ab mediated pathology of the...
... the inclusion of lysine residues in the protein sequence ofthe A fragment but not the B fragment of PE Because only the A fragment must traffic to the cytosol for activity, the lack of lysine residues ... altering the rate of internalization ofthe receptor or influencing the intracellular trafficking The proteome ofthe target cell also influences the pathway We have observed large differences in the ... 14) of patients showed a partial response to treatment 4692 J E Weldon and I Pastan The future of PE-based RITs Many obstacles have been overcome in the development of RITs forthetreatment of...
... evidence forthe optimal period oftreatment and number of treatments? We found evidence forthe efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis ofthe ... exercise dosage is the critical factor is unclear The optimal length oftreatment and the number oftreatment episodes could be useful information forthe marketing of physical therapy for SUI ... effective forthetreatmentof SUI The other studies in the review were considered forthe generalisability of their findings to clinical practice by identifying the patient populations from which the...
... on Cryosurgery fortheTreatmentof Localized Prostate Cancer The supporting systematic literature review and the drafting of this document were conducted by the Cryosurgery forTreatmentof Localized ... upon the peer review comments, the best practice statement was submitted to and approved by the PGC and the Board of Directors ofthe AUA Funding ofthe Panel and ofthe PGC was provided by the ... Activation ofthe heating mode in the CN/P does not affect the thaw rate ofthe distal edges ofthe gland Probe heating affects only the frozen tissue mass juxtaposed to the CN/P and not the distally...
... choice and loading ofthe NM is a compromise between the required efficiency ofthe converter and the market price ofthe NM However, the application of noble metals forthetreatmentof exhaust gas ... are formed in adsorption of reactant molecules on the semi-conducting surface; the formation of these is a function ofthe electronic properties ofthe solid, and the structure and kind of bonds ... mechanism of exhaust treatmentThe aims of this thesis will be then proposed The second chapter introduces basic principles ofthe physico-chemical methods used in the thesis, catalyst synthesis,...
... overall survival of treated animals (Figure 6D) These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans ... collected at the University of Pennsylvania or the University of Michigan After obtaining informed patient consent, ascites was collected either intraoperatively or at the time of therapeutic ... intraperitoneal delivery ofthe drug Despite being a well-documented therapeutic target, the exact function of CD52 remains unknown In the ID8VEGF tumors, VLC account forthe vast majority of tumorassociated...
... measurement of tumor tissue MRI signal at baseline (T10) and then again following the intravenous infusion ofthe Gd-dendrimer (T1), and the in vitro measurement ofthe molar relaxivity (r1) ofthe Gd-dendrimer, ... Significance ofthe luminal glycocalyx layer ofthe BBTB of malignant brain tumor microvasculature The well-defined physiologic upper limit of pore size in the BBTB of 12 nm would be attributable to the ... would be the "nanofilter" that serves as the main point of resistance to the transvascular passage of spherical particles larger than 12 nm in diameter across the BBTB Therefore, in the physiologic...
... variation between the two groups of subjects caused not by thetreatment itself but by variation ofthe clinical scale at the beginning ofthe therapy To test the overall effect of adaptive training, ... was on the opposite side The force generated by the robot in direction d = 3, Fd(t), was only present during the initial 2/3 ofthe total duration ofthe movement (estimated from that ofthe ‘average’ ... compared the primary outcome measures (change in the clinical scores) between the baseline (T0) and the end ofthetreatment (T3), irrespective ofthe training mode (treatment) As regards the kinematic...
... Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2008, 3:9 Statistics The microsoft excel program was used forthe creation ofthe graphs and the SPSS ... minimal loss of physical capacity The technique remains the "gold standard" forthetreatmentof displaced and minimally comminuted olecranon fractures despite the introduction of new Page of (page ... order to improve the biomechanical properties ofthe technique [20] Rowland and Burkhart [21] gave an emphasis on the mathematical need to put the transverse hole forthe figure -of- eight tension...
... was forthe initial trial of VFG, and the other was forthe second trial of VFG after failure of bone consolidation in ipsilateral VFG Patients The mean age ofthe patients at the time of VFG surgery ... cases, the first fracture is reported to occur before the age of year [4] In the current case, one out ofthe cases had a stress fracture at the age of 7.4 years old, and casting healed the fracture ... to 8, the average number being 3.4 The previous surgical treatments were all utilizing intramedullary nails with/without bone grafting The other patients were added forthe purpose ofthe current...
... protocol in our clinic forthetreatmentof osteoporosis The patients were followed with serial physical examinations and radiographs With the use of lateral radiographs centered over the fracture level, ... criteria of kyphotic deformity of more than 20° and/or vertebral body height loss of more than 50 compared to vertebra below The senior author (KJC) performed all surgeries At surgery, the patients ... levels above the fracture into the four screws and after that, torque was applied through the rod pusher to bring the vertebra back to the rod Gentle distraction at the level ofthe fracture...
... Conclusion In the literature, there is no report ofthe use of LISS tibial plates forthetreatmentof paediatric supracondylar fractures ofthe femur They may be considered for Conflict of interest ... the femur to deformity remodeling at this level Thetreatmentof displaced supracondylar fractures ofthe femur depends on the age and size ofthe child, the site, the pattern ofthe fracture and ... over the distal femur forthe best purchase of bone while avoiding violation ofthe growth plate The disadvantages were that the patient might need another operation for implant removal and the...