... suppressed, but the < /b> binding of < /b> the < /b> NM-fragment was little affected These results suggested that the < /b> RS region of < /b> LBR binds to the < /b> DNA region of < /b> chromatin On the < /b> other hand, with the < /b> pretreatment of < /b> the < /b> ... Stimulation of < /b> the < /b> binding of < /b> LBR to chromatin by phosphorylation by a kinase(s) in a synthetic phase egg cytosol Chromatin binding of < /b> beads bearing GST–NK was increased by pretreatment with a synthetic ... phosphorylation inhibits the < /b> binding of < /b> LBR to p34/p32 [23], whereas there has been no report about the < /b> effect on the < /b> interaction of < /b> LBR and chromatin Identification of < /b> the < /b> kinase(s) responsible for the < /b> stimulation...
Ngày tải lên: 22/02/2014, 04:20
... recommended by the < /b> vendor The < /b> majority of < /b> the < /b> cell lines were used within months of < /b> acquisition and no re-authentication was performed For the < /b> DSMZ cell bank STR DNA typing is performed for authentication ... further underscores the < /b> significance of < /b> the < /b> general observation between polyploidy and resistance For these data, we hypothesize there is a selective growth advantage for the < /b> subpopulation of < /b> ... modal number of < /b> 48 for the < /b> primary population of < /b> cells, but also 12% of < /b> the < /b> cell population was polyploid (See Additional File 1, Table S2 for karyotype data) To evaluate the < /b> effect these subpopulations...
Ngày tải lên: 18/06/2014, 22:20
o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt
... recommended by the < /b> vendor The < /b> majority of < /b> the < /b> cell lines were used within months of < /b> acquisition and no re-authentication was performed For the < /b> DSMZ cell bank STR DNA typing is performed for authentication ... further underscores the < /b> significance of < /b> the < /b> general observation between polyploidy and resistance For these data, we hypothesize there is a selective growth advantage for the < /b> subpopulation of < /b> ... modal number of < /b> 48 for the < /b> primary population of < /b> cells, but also 12% of < /b> the < /b> cell population was polyploid (See Additional File 1, Table S2 for karyotype data) To evaluate the < /b> effect these subpopulations...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation" pps
... Translocation of < /b> p65 is inhibited by WFA pre-treatment leading to decreased FITC-associated fluorescence in nuclei of < /b> KKLEB cells as demonstrated in the < /b> bottom row fashion by ~70% in the < /b> KKLEB cells ... CF is regulated largely by activation of < /b> NF B and transcription of < /b> pro-inflammatory genes regulated by this transcription factor [16,20] Therefore, we examined the < /b> effect of < /b> WFA pre-treatment on ... NF B commonly refers to a p50–p65 heterodimer, which is the < /b> major Rel/NF B complex in most cells [21,22] In order to further characterize inhibition of < /b> NF B by WFA, we investigated the < /b> effect of...
Ngày tải lên: 11/08/2014, 08:22
the book of css3 - a developer's guide to the future of web design - by peter gasston
... old browsers will get the < /b> basic stylesheet instead, which is probably better for them as they won’t be able to cope with the < /b> advanced features I’ll be teaching throughout the < /b> rest of < /b> this book The < /b> ... THE < /b> BOOK OF < /b> CSS3 THE < /b> BOOK OF < /b> CSS3 A Developer's Guide to the < /b> Future of < /b> Web Design by Peter Gasston San Francisco THE < /b> BOOK OF < /b> CSS3 Copyright © 2011 by Peter Gasston All rights ... but it describes the < /b> width of < /b> the < /b> device that is rendering the < /b> page When dealing with web pages, the < /b> device width is the < /b> width of < /b> the < /b> screen that’s displaying the < /b> page rather than the < /b> width of...
Ngày tải lên: 20/09/2013, 09:09
A discourse analysis of presuppositions in the declaration of independence made by president ho chi minh = phân tích diễn ngôn các tiền giả định trong tuyên ngôn độc lập của chủ tịch hồ chí minh
... Table Proportions of < /b> subtypes of < /b> definite descriptions to the < /b> total By using any of < /b> the < /b> definite descriptions, the < /b> speaker is assumed to be committed to the < /b> existence of < /b> the < /b> entities named For ... knowledge that the < /b> weather in Moscow is very cold and then the < /b> husband should bring enough warm clothes with him Rather, they are part of < /b> the < /b> same group The < /b> communities of < /b> people who can be assumed ... like before, after, when can be replaced with other expressions For example, instead of < /b> “before fleeing they massacred a great number of < /b> our political prisoners detained at Yen Bai and Cao Bang”,...
Ngày tải lên: 14/12/2013, 00:41
Tài liệu The message of a master - By John McDonald pdf
... station for some delightful music, but because of < /b> there being a number of < /b> others on the < /b> air, your reward is a jumble of < /b> confusion But should you reach that station when others are temporarily off, ... suffer all sorts of < /b> lack, misery and unhappiness when such inferior creatures as the < /b> beasts of < /b> the < /b> field, the < /b> birds of < /b> the < /b> air and the < /b> fish of < /b> the < /b> sea are bountifully supplied For any man, no ... matter for each individual Accomplishment of < /b> anything, in any line, is the < /b> result < /b> of < /b> the < /b> operation of < /b> this inner force, discovered and set to work, and this must be done by each one for himself There...
Ngày tải lên: 15/12/2013, 06:15
Tài liệu The Science of Being Well - By Wallace D.Wattles doc
... spine, by the < /b> faith healer with prayer, by the < /b> food scientist with bills of < /b> fare, by the < /b> Christian Scientist with a formulated creed statement, by the < /b> mental scientist with affirmation, and by the < /b> ... This Substance creates by thought, and its method is by taking the < /b> form of < /b> that which it thinks about The < /b> thought of < /b> a form held by this substance causes it to assume that form; the < /b> thought of < /b> a ... find the < /b> thief and recover their treasures, and hastening to the < /b> cellar of < /b> the < /b> convent they dug up the < /b> bones of < /b> a murderer, who had been buried there many years before These they placed in the...
Ngày tải lên: 21/01/2014, 21:20
Tài liệu The Science of Getting Rich - By Wallace D.Wattles docx
... substance always takes the < /b> form of < /b> that which it thinks about The < /b> grateful mind is constantly fixed upon the < /b> best; therefore it tends to become the < /b> best; it takes the < /b> form or character of < /b> the < /b> best, ... navigate through The < /b> Science of < /b> Getting Rich ebook At the < /b> left side of < /b> your screen, there is a small vertical panel labeled "Bookmarks" This is the < /b> table of < /b> contents for the < /b> ebook The < /b> bookmarks are ... arranged in a stepped fashion similar to the < /b> table of < /b> contents in a printed book There is one bookmark for the < /b> Preface, one for each of < /b> the < /b> seventeen chapters and one for each of < /b> the < /b> five appendices...
Ngày tải lên: 26/01/2014, 16:20
Tài liệu The State of Computer Security BY Marcus J. Ranum CSO Tenable Network Security, Inc. doc
... Security market is about $20 bn • Subtract Cisco, IBM, Oracle, Symantec, Microsoft, McAfee • Top vendors account for all the < /b> industry except for about $1 bn TopHeavy • $1 bn among 190 start-ups ... a hobby” (Peter Kuper, Morgan Stanley) • Further pressure on the < /b> “little guys” • Think of < /b> Checkpoint and ISS as “little guys” but really where can they go? Upmarket and compete with Cisco? There ... years (The < /b> good news is, it will be worse for the < /b> ones you hate) Regulatory Changes • The < /b> lawyers are here!! • Security practitioners have been asking for it “and now you got it!” • SarbOx, EU...
Ngày tải lên: 14/02/2014, 16:20
Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... note that the < /b> structure of < /b> the < /b> E coli protein in the < /b> substrate-bound form has not been reported [13] Details of < /b> the < /b> structural basis for the < /b> biochemically observed inhibition of < /b> plant PS by pantoate, ... conditions The < /b> occurrence of < /b> a b- strand is corroborated by the < /b> absence of < /b> backbone HN–HN NOEs Mapping chemical shift changes upon substrate binding Binding of < /b> substrates to nPS was studied by both ... inhibition by one of < /b> the < /b> substrates of < /b> a reaction has also been observed in the < /b> case of < /b> adenylosuccinate synthetase, one of < /b> whose substrates, IMP, binds to the < /b> GTP-binding site and inhibits the...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx
... prerequisite for cleavage of < /b> the < /b> bond between C20 and C22 [1,14] Another difference between the < /b> metabolism of < /b> vitamin D3 and cholesterol by P450scc is that the < /b> dissociation of < /b> intermediates occurs for the < /b> ... D from the < /b> bloodstream for further metabolism [4] In conclusion, the < /b> identification of < /b> new metabolites of < /b> vitamin D3 made by the < /b> action of < /b> P450scc will enable us to proceed with further biological ... were identified by purifying them and determining the < /b> substrates from which they arose by the < /b> action of < /b> P450scc, as well as the < /b> products that they gave rise to This revealed both the < /b> major and...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu An Account of the Proceedings on the Trial of Susan B. Anthony doc
... amendment, absolutely prohibited from abridging the < /b> privileges of < /b> the < /b> citizen, either by enforcing existing laws, or by the < /b> making of < /b> new laws, the < /b> right of < /b> every "citizen" to the < /b> full exercise of < /b> this ... from the < /b> text of < /b> G & W "The < /b> verdict is to be the < /b> result < /b> of < /b> the < /b> deliberation of < /b> the < /b> jury upon all the < /b> evidence in the < /b> case The < /b> Court has no right to anticipate the < /b> verdict by an expression of < /b> opinion ... insist the < /b> prisoner has been tried according to the < /b> established forms of < /b> law MISS ANTHONY Yes, your honor, but by forms of < /b> law all made by men, interpreted by men, administered by men, in favor of...
Ngày tải lên: 20/02/2014, 08:20
TECHNIQUES FOR THE ANALYSIS OF ORGANIC CHEMECALS BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (ICP-MS) pptx
... used, rather than pure oxygen, avoiding the < /b> use of < /b> highly flammable or explosive gases in the < /b> laboratory The < /b> oxygen is added either in the < /b> spray chamber or using a T-connector before the < /b> torch ... pressure is controlled by cooling the < /b> spray chamber, where the < /b> sample aerosol is generated This can be best affected by means of < /b> a Peltier device, which controls the < /b> spray chamber to a selected temperature, ... and, in the < /b> case of < /b> the < /b> sample uptake tubing, care must also be taken to avoid contamination of < /b> the < /b> sample through contact with the < /b> tubing material For routine analysis of < /b> organic solvents, the < /b> normal...
Ngày tải lên: 05/03/2014, 21:20
THE ANTHROPOLOGY OF ONLINE COMMUNITIES BY Samuel M.Wilson and Leighton C. Peterson doc
... access Although there have been examples of < /b> effective use of < /b> the < /b> Internet by small groups—such as the < /b> Zapatista movement’s successful use of < /b> the < /b> Internet to gain support for their cause (http://www.ezln.org) ... statements made in publicly accessible discussion boards or other communication spaces are in the < /b> public domain and may thus be freely used by researchers For others, this is a form of < /b> electronic eavesdropping ... In Cyberspace: First Steps, ed M Benedikt, pp 1– 25 Cambridge, MA: MIT Press Berners-Lee T, Fischetti M 1999 Weaving the < /b> Web: the < /b> Original Design and Ultimate Destiny of < /b> the < /b> World Wide Web by Its...
Ngày tải lên: 06/03/2014, 21:20
www.it-ebooks.info .Introducing Microsoft WebMatrix ™ ® www.it-ebooks.info .www.it-ebooks.info .Introducing Microsoft WebMatrix ™ ® Laurence Moroney www.it-ebooks.info .Published with the authorization of Microsoft Corporation by: O’Reilly Media, pot
... about how to build the < /b> next huge website for billions of < /b> users, this book (and WebMatrix) probably aren’t for you Organization of < /b> This Book The < /b> goal of < /b> this book is to take you step < /b> by step < /b> through ... of < /b> the < /b> stack work together, exploring them by building a website with WebMatrix That’s one of < /b> the < /b> strengths of < /b> WebMatrix Although many of < /b> these technologies are disparate, WebMatrix handles the < /b> ... Exploring the < /b> Ribbon The < /b> first thing to look at is the < /b> ribbon across the < /b> top of < /b> the < /b> window The < /b> ribbon provides tools that are relevant to managing your site You’ll explore these one by one For convenience,...
Ngày tải lên: 06/03/2014, 23:20
Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris ppt
... as the < /b> bufferế Substrate breakdown was monitored by following the < /b> changes of < /b> absorbance at 410 or 324 nm for paranitroanalide or thiobenzylester derivatives, respectively When the < /b> later substrate ... evaluate the < /b> inhibitory properties of < /b> bound trappin-2, as this covalent linking may increase signicantly the < /b> bioavailability of < /b> such an inhibitor at the < /b> site of < /b> inammation, e.g in the < /b> case of < /b> therapeutic ... enzyme (E), inhibitor (I), substrate (S), and their complexes are in thermodynamic equilibrium The < /b> active concentration of < /b> both recombinant inhibitors was deduced from the < /b> volume of < /b> inhibitor necessary...
Ngày tải lên: 07/03/2014, 15:20
The Principles of Successful Freelancing by Miles Burke
... often be surprised at the < /b> small difference in final figures, and realize the < /b> benefit of < /b> being able to hand the < /b> equipment back or upgrade it at the < /b> end of < /b> the < /b> lease term Creating Your Brand: the < /b> ... Notice of < /b> Liability The < /b> author and publisher have made every effort to ensure the < /b> accuracy of < /b> the < /b> information herein However, the < /b> information contained in this book is sold without warranty, either ... the < /b> world a better place through the < /b> technical editing of < /b> SitePoint books and kits He is also a busy father of < /b> five, enjoys coffee, and often neglects his blog at http://tetlaw.id.au/ About the...
Ngày tải lên: 16/03/2014, 10:23
The raman effect a unified treatment of the theory of raman scattering by molecules derek a long
... detailed information – albeit in code – about the < /b> structure of < /b> matter It is the < /b> purpose of < /b> this book to provide the < /b> means for deciphering the < /b> information carried by the < /b> scattered light A number of < /b> light-scattering ... systems, reviews and books by L D Barron, L Hecht and L A Nafie; for rotational and vibration-rotation Raman scattering, reviews by S Brodersen, by W J Jones and by A Weber; for vibrational and electronic ... (Electronic) The < /b> Raman Effect The < /b> Raman Effect A Unified Treatment of < /b> the < /b> Theory of < /b> Raman Scattering by Molecules Derek A Long Emeritus Professor of < /b> Structural Chemistry University of < /b> Bradford Bradford,...
Ngày tải lên: 17/03/2014, 14:46
Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc
... B, the < /b> overexpression of < /b> Synoviolin enhanced the < /b> production of < /b> Ab40 and Ab42 by about twofold, whereas the < /b> secretion of < /b> soluble APP was not changed in these cells Figure 5C also showed that the < /b> ... and the < /b> intracellular APP level was not changed by the < /b> overexpression of < /b> Synoviolin Previously, the < /b> targeting of < /b> NCT to the < /b> cell surface enhanced Ab generation, because one of < /b> the < /b> main Ab generation ... likely to be in the < /b> cell surface [6] Therefore, it is possible that the < /b> overexpression of < /b> Synoviolin enhances the < /b> localization of < /b> NCT at the < /b> cell surface, resulting in an enhancement of < /b> Ab generation...
Ngày tải lên: 23/03/2014, 04:20