multifunctional nanoparticles for cancer therapy
nanotechnology for cancer therapy, 2007, p.810
... Chapter Multifunctional Nanoparticles for Cancer Therapy 59 Todd J Harris, Geoffrey von Maltzahn, and Sangeeta N Bhatia Chapter Neutron Capture Therapy of Cancer: Nanoparticles ... serve as multifunctional nanovector devices for cancer therapy, imaging, diagnostics, and monitoring of response to anti-tumor therapy Although the development of nanoplatforms for cancer therapeutics ... anti-tumor therapy Given the wide variety of nanovectors and nanoplatforms, Nanotechnology for Cancer Therapy cannot possibly cover each nanoscale application that has potential for use in anti-tumor therapy...
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báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
... in assessing tumor responses to therapy (i.e., estimating HER1 expression) and would provide accurate data for performing dosimetric calculations for radioimmunotherapy [36] The caveat to translating ... Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda MD 20892, USA Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, Center for Cancer ... candidates for targeted therapy due to their specificity, with their long residence time in the blood of days to weeks, they are not ideal carriers for imaging probes; it is extremely difficult to perform...
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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR POTENTIAL CELL TARGETING, IMAGING, AND CANCER THERAPY APPLICATIONS HUANG CHAO (B.ENG., TIANJIN UNIVERSITY) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... Superparamagnetic iron oxide nanoparticles (SPIONs) are very useful for biomedical applications, such as magnetic resonance imaging (MRI), hyperthermia for cancer therapy, cell targeting, drugs ... potential for various biomedical applications, including MRI for cell targeting and monitoring, drug/gene delivery, hyperthermia for cancer treatment, etc In addition, in contrast to other inorganic nanoparticles, ...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
... (Zamecnik and Stephenson 1978; Crooke 1999) 1.6 Antisense Oligonucleotides for Gene-Related Disease Therapy Antisense for therapy is an active field of drug development (reviews in Agrawal 1996 ... oligonucleotides to the in vivo context differ somewhat for aptamers and for antisense Target accessibility is much less of a problem for aptamers than for antisense Many aptamer targets are extracellular ... subject of intense, sometimes excessive speculations for biomedical applications, often before B Tavitian Fig Oligonucleotides and biological information Table Oligonucleotides are modulators of...
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The use of gold nanostructures in the imaging and therapy of cancer
... Introduction…………………………………………………………………… 41 2.2 Mie solution for spherical gold nanostructures…………………………… ……45 2.2.1 Mie coefficients for homogenous gold nanoparticles ………………… 45 2.2.2 Mie coefficients for core-shell gold nanoshells……………………………47 ... critical for early pre-cancerous detection and rational therapeutic intervention This thesis examines the use of gold nanostructures as an exogenous cancer- specific optical contrast agents for reflectance-based ... anionic species of the form [Au(OH)xCl4-x]¯ Whilst the pH is raised to by NaOH to form the dominant specie AuCl(OH)3¯ for DP process of seeding, the pH is raised to 10.1 by K2CO3 to form the dominant...
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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx
... Y, Maeda H: A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res 1986, 46:6387 Duncan ... Tokumitsu H, Ichikawa H, Fukumori Y: Chitosan-gadopentetic acid complex nanoparticles for gadolinium neutron-capture therapy of cancer: preparation by emulsion-droplet coalescence technique and characterization ... IC: Polymeric nanomedicine for cancer therapy Prog Polym Sci 2008, 33:113 Sheng Y, Liu CS, Yuan Y, Tao XY, Yang F, Shan XQ, Zhou HJ, Xu F: Longcirculating polymeric nanoparticles bearing a combinatorial...
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Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
... 55 chemotherapy for ovarian cancer Med Pediatr Oncol 1993; 21: 521-524 Baeksgaard L, Sorensen JB Acute tumor lysis syndrome in solid tumors-a case report and rewiew of the literature Cancer Chemother ... non-Hodgking lymphoma [15] Then PEG-uricase was proposed for cases of uncontrolled gout or for intolerance or not compliance to standard therapy [16] It was a mammalian, recombinant urate oxidase, ... Syndrome (TLS) Already before 2002, when Food and Drugs Administration (FDA) of US has approved the use of 85 urate oxidase for the management of paediatric patients at risk for TLS (Tumor Lysis...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... target for therapy Results from studies using several in vivo model systems support the notion that enzymatic activities responsible for syndecan-1 modification are valid targets for myeloma therapy ... functions in cancer Semin Cancer Biol 12, 173–186 12 Fuster MM & Esko JD (2005) The sweet and sour of cancer: glycans as novel therapeutic targets Nat Rev Cancer 5, 526–542 New concepts for heparanase ... for heparanase (upper) Nuclear heparanase is associated with decreased levels of phospho-EGFR, lower lymph vessel density, and favorable prognosis of head and neck cancer patients (see text for...
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adobe digital imaging how-tos 100 essential techniques for photoshop cs5, lightroom 3, and camera raw 6
... transmitted in any form by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher For information on getting permission for reprints ... all the information, image by image, is a recipe for frustration (Figure 3a) Metadata presets are a way to apply several pieces of IPTC information to many photographs at one time For example, ... stands for Digital Negative Group and was designed by Adobe as a common raw format option for photographers It maintains all the quality and nondestructive editing benefits of proprietary raw file formats;...
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patel, chellapa - sparse representations and compressive sensing for imaging and vision
... performance In this section, we will present a few methods for performing various tracking tasks that take advantage V.M Patel and R Chellappa, Sparse Representations and Compressive Sensing for ... Sensing for Vision Fig 4.2 Comparison between ARCS and a non-adaptive method for a dataset consisting of vehicles moving in and out of the field of view (a) Foreground sparsity estimates for each ... noise For both of the above examples we used SPGL1 [8] algorithm for solving the minimization problems In [23], [47], a theoretical bound on the number of samples that need to be measured for a...
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báo cáo hóa học:" Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging" potx
... Background Prostate cancer is the most frequently diagnosed cancer and the second leading cause of cancer- related deaths for males in the USA One promising approach in prostate cancer diagnosis ... documented in small cell lung cancers [3], prostate cancers [4, 5], breast cancers [6-8] and others [9] In prostate cancer, the GRPR expression has been tied to neoplastic transformation [10], cell migration ... showed GRPR-dependant tumor uptake for both tracers Conclusion: Both 64Cu/NOTA-monomer and 64Cu/NOTA-dimer are suitable for detecting GRPR-positive prostate cancer in vivo by PET Tumor retention...
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Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
... staining for types I and III collagens, patchy staining for type II collagen, and a little for type VI collagen Most glycosaminoglycan staining was for chondroitin-4-sulfate, with less for keratan ... 3-B-3(–) and 7-D-4, which had no pretreatment Sections were fixed in 10% formalin before incubation with the primary antibody (before the enzyme digestion, in the case of the proteoglycan antibodies) ... 13.2 for these groups There was a correlation (r = 0.9, P < 0.001) between the two scoring systems for all the 26 cartilage samples Consistency of scoring between the three observers was higher for...
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Báo cáo khoa học: "Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections" docx
... and Metastatic Liver Cancer J Transl Med 2007, 14(5):15 Gulec SA, Mesoloras G, Stabin M: Dosimetric Techniques in Y-90 Microsphere Therapy of Liver Cancer: The MIRD Equations for Dose Calculations ... emerged as an effective liverdirected therapy with a favorable therapeutic ratio SIRT, both as a stand-alone therapy and in conjunction with systemic or regional chemotherapy (chemo-SIRT), has been ... continued systemic chemotherapy for a total of courses with no significant toxicity noted At 3month follow-up evaluation, based on a favorable tumor response, the patient's improved performance status,...
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Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... 62°C for ADAMs 8, 9, 10, 12, 17, 20, 21, 28 and 30, 67°C for ADAM15, 64°C for VEGFR-1, 63°C for VEGFR-2 and neuropilin-1 and 65°C for β-actin, and minute at 72°C, followed by minutes at 72°C for ... manufacturer's protocols Cycling conditions were 50°C for minutes, 95°C for 10 minutes, and then 40 cycles at 95°C for 15 seconds and 60°C for minute Primers were designed and selected using Primer ... searches were performed to confirm the specificity of the probes Hybridization with the probes was performed at 42°C for 16 h, and the sections were washed in 2× standard saline citrate/50% formamide,...
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Báo cáo khoa học: "Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers" docx
... of radical RT for prostate cancer Acknowledgements This work was supported by grants from the Calgary Health Region Prostate Cancer Research Competition (2004) and the Alberta Cancer Board Research ... March 2010 Accepted: 10 June 2010 Published: 10 June 2010 undergoing conformal 3D external beam radiation therapy for prostate cancer based on an analysis of 10,327 pretreatment daily ultrasound ... Bosch W, Purdy J, Perez C: A critical evaluation of the planning target volume for 3-D conformal radiotherapy of prostate cancer Int J Radiat Oncol Biol Phys 1998, 42:213-221 Meijer G, de Klerk J,...
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Báo cáo khoa học: "Value of diffusion weighted MR imaging as an early surrogate parameter for evaluation of tumor response to high-dose-rate brachytherapy of colorectal liver metastase" docx
... colorectal liver metastasis in segment VII scheduled for high-dose-rate brachytherapy (HDR-BT) The implantation of one brachytherapy catheter was performed under MRI guidance (A) The tumor enclosing ... advanced cancer patients Hence, larger clinical studies have to confirm the ability of DWI to identify treatment response to anticancer therapy and identify the best time point to perform early ... that we performed an ANOVA with the adjusted F-Test by Greenhouse-Geisser to get a global test for time effects in each of the two groups Paired t test with Bonferroni correction for multiple...
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Báo cáo khoa học: "Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results" ppsx
... SBRT is considered a therapeutic option in stage I NSCLC either for inoperable patients or for patients refusing surgery SBRT for lung cancer is under evaluation in clinical trials Japan Clinical ... doublevacuum whole body immobilization system for stereotactic body radiation therapy Technol Cancer Res Treat 2004, 3:59-67 Stevens CW, Munden RF, Forster KM, Kelly JF, Liao Z, Starkschall G, ... volume in radiotherapy treatment planning for lung cancer? Radiother Oncol 1998, 48:71-77 Hof H, Herfarth KK, Münter M, Essig M, Wannenmacher M, Debus J: The use of the multislice CT for the determination...
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Báo cáo khoa học: " Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia" pot
... radiation therapy in head and neck cancers: An update Head Neck 2007, 29:387-400 Cerezo L, Pérez L, López M, Cruz A: Ipsilateral irradiation for oropharynx and oral cavity cancer: a proposal for case ... after the Figure Oral cavity cancer Oral cavity cancer Patient with a pT2N0M0 carcinoma of the left lateral border of tongue treated with postoperative radiation therapy for close margin and perivascularperineural ... radiotherapy in carcinoma of the tonsillar region Int J Radiat Oncol Biol Phys 2001, 51:332-43 Jensen K, Overgaard M, Grau C: Morbidity after ipsilateral radiotherapy for oropharyngeal cancer...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study J Clin Oncol 1999, 17:2127-2136 Mehta M, Bradley K: Radiation therapy for leptomingeal cancer Cancer Treat Res ... in its current formulation does not directly incorporate the effects of chemotherapy, which has emerged as a central component of therapy for patients with medulloblastoma Chemotherapy may improve ... behind to minimize morbidity Alternatively, chemotherapy can reduce the tumor burden when administred before and/or with radiotherapy In addition, chemotherapy may substantially increase radiosensitivity...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot
... Clinical diagnosis is the cornerstone for treatment of human disease Elucidation of the genetic basis of human disease provides crucial information for diagnostics, and for understanding mechanisms of ... 69978, Israel Full list of author information is available at the end of the article thus far for non-syndromic sensorineural hearing impairment [1] and many more for syndromes including hearing ... responsible for 27% of congenital hearing loss among Israeli Jews [4] and 14% of congenital hearing loss among Palestinian Arabs [5] Each of the other known genes for hearing loss is responsible for...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008