motivational interviewing and health behavior change counseling
Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
... stability and toxicity of PANs, and further investigated the sustained release behavior in vivo of drug loading in PANs PA was firstly synthesized and characterized by FT-IR and 1H NMR, and then ... normal diet, and water was provided ad libitum Animals were observed carefully for the onset of any signs of toxicity and monitored for changes in food intake and body weight at 1, 8, and 15 days ... acetyl protons at 1.8–2.2 ppm and B is that of OH protons and H-1 to H-6 protons of pullulan moiety observed at more than 3.5 ppm Preparation and characterization of PANs and PA/EPI Nanoparticles...
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Tài liệu Copper and Fiber Labeling Software and Labeling Sheets docx
... for ADC’s C6 HighBand 25 and CopperTen 20-Pair termination blocks Each label sheet contains 18 individual labels SH 6462 408-00 ADCLS-HB25C Paper label for ADC’s C6 Ultim8 and CopperTen 8-Pair ... ADC’s C5e and C6 silk screen patch panels Each label sheet contains 125 individual labels www.adc.com • +1-952-938-8080 • 1-800-366-3891 TrueNet® Copper and Fiber Labeling Software and Labeling ... TrueNet® Copper and Fiber Labeling Software and Labeling Sheets Ordering Information Description UOM Products that use the label...
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Tài liệu Stability and Control of Large-Scale Dynamical Systems pptx
... admiration, and love Throughout the odyssey of her life her devotion, sacrice, and agape were unconditional, her strength, courage, and commitment unwavering, and her wisdom, intelligence, and pansophy ... of the eternal While time is everlasting, time is the outcome of change (motion) in the universe And as night and day and month and the like are all part of time, without the physical universe ... collection of interacting subsystems The behavior and properties of the aggregate large-scale system can then be deduced from the behaviors of the individual subsystems and their interconnections Often...
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Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc
... systems, such as Switzerland and Germany, some banks have run into trouble Regional banks in Switzerland failed, and Germany’s BfG Bank suffered huge losses (DM 1.1 billion) in l992 and needed a capital ... Property and casualty Pension funds Private Public (state and local government) Finance companies Mutual funds Stock and bond Money market Depository institutions (banks) Commercial banks Savings and ... 35 percent were foreign exchange derivatives, and the remainder were equity and commodity derivatives.9 In addition, most of these derivatives were held by large banks, and were held primarily...
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Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... to understand what makes proteins ÔtickÕ and to engineer proteins with native-like properties In this review we discuss combinatorial approaches toward understanding protein structure and stability ... required for catalysis; screens and selections are possible [73–77] cellular function demands expression and proteolysis resistance) Thus, in general, proteins that bind ligands or catalyze reactions ... Between 0.2% and 2% of mutants were active, depending upon the library and level of function demanded The residues in active clones were dominated by Ala, Cys, Thr, Val, Ile, Leu, Met and Phe, a...
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Đề tài " Stability and instability of the Cauchy horizon for the spherically symmetric Einstein-Maxwell-scalar field equations " doc
... past I − (S) Similarly, one can define causal and chronological future J + (S) and I + (S), and thereby, in a standard way, the domain of influence and domain of dependence of an achronal set S ... ) ≥ (u , v ) − (u , v ) for u > u and v > v , and similarly, with the roles of u and v interchanged We will prove (113); the analogous result with u, v interchanged follows immediately We can ... point of intersection of the right-I and the corresponding left-I region) and parametrize the u = line segment by ≤ v ≤ V with s = (0, 0) and p = (0, V ), and parametrization determined by the...
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Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot
... PfPNP shows an absolute specificity for inosine and guanosine [12] SsMTAPII and PfPNP show features of exceptional thermophilicity and thermostability and are characterized by stabilizing disulfide ... their stability and to preserve their folded state under extreme conditions Results and Discussion SsMTAPII and PfPNP require a CXC motif to preserve their folded state SsMTAPII and PfPNP are highly ... stability and folding in hyperthermophilic disulfide-containing proteins and could provide useful information with respect to engineering stable proteins and enzymes for therapeutic and industrial...
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Báo cáo khoa học: Effect of flanking bases on quadruplex stability and Watson–Crick duplex competition pptx
... lengths and their respective complementary strand sequences used in this study G0 and C0 are the core c-kit quadruplex-forming sequence and its complementary strand sequence, respectively G4G12 and ... c-kitG8, and are also shown in Table The Tm values for c-kitG0, c-kitG4 and c-kitG6 were 60, 55 and 51 C, respectively The Tmelt and Tanneal values for c-kitG8 were 50 and 47 C, respectively, and ... complementary strand binding to preformed quadruplex DHITC is the enthalpy change and DSITC is the entropy change for duplex formation DGITC is the free energy change for duplex formation and was determined...
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Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc
... dissociation and folding ⁄ assembly behaviors of Aacpn10 and Aacpn10del-25 [24,26] The results have been compared to the corresponding data for the mesostable human mitochondrial cpn10 (hmcpn10) [27] and ... cysteines and are poorer in disulfide bonds than their thermostable and mesostable Table Thermal midpoints (TM), thermodynamic stability (DGU), and kinetic folding ⁄ unfolding parameters (kf and ku) ... 60 °C) and kJÆmol)1 (pH 7, 40 °C) for PfPCP-142 ⁄ 188S and BaPCP, respectively Unfolding-rate constants for PfPCP-142 ⁄ 188S and BaPCP are also drastically different (1.6 · 10)15Æs)1 and 1.5...
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Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf
... intensity and exposure to solvent in a number of Trp residues (60d, 96, 148, 207, and 215) [12] In particular, Trp207 and Trp29 residues, located at the boundary between the A- and B-chains and interacting ... in vitro and its hemorrhagic phenotype in vivo Results and Discussion Effect of pH on thrombin catalytic activity and inhibition The pH-dependent steady-state amidase activities of WT and K9-deleted ... 8.45 to 8.87 in the free enzyme and from 9.04 to 9.36 in the substrate-bound form, for WT thrombin and DK9 mutant, respectively Table 1B reports changes in the kcat and kcat ⁄ Km values at the three...
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Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx
... P37A, P38A and the A37A38 double mutant and have examined chemical shift perturbations and the pattern of NOEs in the vicinity of the mutation sites Deviations of Ha signals from random coil ... (GdmCl) and )25.8 kJÆmol)1 (urea); m-values are estimated as follows in urea, mfold ¼ 1604 ± 88 JÆmol)1ÆM)1 and munfold ¼ 2919 ± 43 J mol)1ÆM)1 (B) Refolding and unfolding data for WT* as in (A) and ... Fig 4B and formation of an intermediate collapsed state at low denaturant concentrations ð6Þ ð7Þ where kfold° and kunfold° are the rate constants for folding and unfolding of WT*, kfold and kunfold...
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Báo cáo Y học: Processing, stability, and kinetic parameters of C5a peptidase from Streptococcus pyogenes pptx
... process, detected by changes in tryptophan fluorescence intensity ratio and by changes of the ellipticity, was biphasic and two cooperative transitions were observed at Tm1 ¼ 50 °C and Tm2 ¼ 70 °C ... E280, 0.1% ¼ (5690 W + 1280Y + 120S-S)/M, where W, Y, and S-S represent the number of Trp and Tyr residues and disulfide bonds, respectively, and M represents the molecular mass [11,12] Molecular ... peptide and then plotted as a function of time The identity of peptides was determined by NH2-terminal sequence- and mass spectral analysis Treatment of the QTPDEAAEETI and AEETIADD ANDL synthetic...
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FINANCIAL LIBERALIZATION, MACROECONOMIC (IN)-STABILITY, AND PATTERNS OF DISTRIBUTION pptx
... of change of price indices and of nominal exchange rates Between the last weeks of 1999 and 2000, the exchange rate basket rose by 20.3%; but rates of change in WPI and CPI indices were 32.7 and ... Leiderman and Reinhart (1996), Diaz-Alejandro (1985), Kaminsky and Reinhart (1999), Frenkel (1995), and Agenor and Montiel (1999, chp 8) For individual country experiences see also Corbo (1985), and ... Corbo (1985), and Edwards and Edwards (1991) on Chile; Dornbusch and Werner (1994) on Mexico; Patinkin (1993), and Bruno (1993) on Israel; and Dornbusch (1995), and Frenkel and Fanelli (1998) on...
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Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... Identical and similar residues within the TRP family are shown in dark and light green, those within the TTR family in dark and light blue, and those within the TLP subgroup in dark and light ... regions are found at sites corresponding to b-strands B and E in TLPs, and to a-helix E in TTRs and TRPs (B) Phylogenetic tree of TRPs, TTRs, and TLPs The tree was based on the multiple sequence ... Bedford, MA, USA), and purified on a Q-Sepharose Fast Flow anion exchange column (GE Healthcare, Uppsala, Sweden) equilibrated with 20 mm Tris ⁄ HCl (pH 8.0) and 50 mm NaCl, and eluted with a linear...
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Báo cáo khoa học: Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2 pdf
... deamidation site and four of the main oxidation sites The second one contains the remaining two main oxidation sites and two minor deamidation sites, and the third one a minor deamidation site and three ... structure and properties of the CRMP-2 protein, both in solution and in the crystal state Divalent cations have a drastic effect on both the stability and oligomeric state of CRMP-2, and a number ... asymmetric unit using molrep [51], and refinement and model building were carried out iteratively using refmac [52], phenix refine [53,54] and coot [55] The coordinates and structure factors were deposited...
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power system stability and control chuong (1)
... absence of standards, several manufacturers have developed proprietary ‘‘flicker’’ meters In recent years, an effort has been made to standardize the definition of ‘‘flicker,’’ and to standardize the ... matter of experience, and Ohm’s law There are many examples of disturbance data in books such as The BMI Handbook of Power Signatures, Second Edition, and the Dranetz Field Handbook for Power Quality ... rms data Figure 33.7 shows a significant change in the current waveform when the current changes from zero to nearly 100 amps peak The shape of the waveform, and the phase shift with respect to the...
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power system stability and control chuong (2)
... The Engineering Handbook, Third Edition, Richard C Dorf The Handbook of Formulas and Tables for Signal Processing, Alexander D Poularikas The Handbook of Nanoscience, Engineering, and Technology, ... Handbook, Third Edition, Joseph D Bronzino The Circuits and Filters Handbook, Second Edition, Wai-Kai Chen The Communications Handbook, Second Edition, Jerry Gibson The Computer Engineering Handbook, ... Measurement, Instrumentation, and Sensors Handbook, John G Webster The Mechanical Systems Design Handbook, Osita D.I Nwokah and Yidirim Hurmuzlu The Mechatronics Handbook, Second Edition, Robert...
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power system stability and control chuong (3)
... Plains (Kansas, Oklahoma, and Texas), the winds are strongest in the spring (March and April) and weakest in the summer (July and August) Utilities here are summer peaking, and hence need the most ... 1-4 Land Rights The wind is a free, clean, and inexhaustible energy source It has served humankind well for many centuries by propelling ships and driving wind turbines to grind grain and pump ... 1970s was a 1250-kW machine built on Grandpa’s Knob, near Rutland, Vermont, in 1941 This turbine, called the Smith-Putnam machine, had a tower that was 34 m high and a rotor 53 m in diameter The rotor...
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power system stability and control chuong (4)
... a result, the compressor and the expander must operate at the same time and must have the same air mass flow rate In the case of a CAES plant, the compressor and the expander can be sized independently ... are quiet and non-polluting, and can be installed near load centers and existing suburban substations These have round-trip AC–AC efficiencies in the range of 85%, and can respond to load changes ... but the compressor and the expander operate independently In a combustion turbine, the air that is used to drive the turbine is compressed just prior to combustion and expansion and, as a result,...
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