motility in head and neck carcinoma
Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
Ngày tải lên :
18/06/2014, 22:20
... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...
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Báo cáo sinh học: " Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" potx
Ngày tải lên :
18/06/2014, 22:20
... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... methods for genotyping (e.g direct sequencing, pyrosequencing or TaqMan-genotyping) were not considered Figure TLR4 immunohistochemistry in head and neck squamous cell carcinomas (A) Strong (score ... well as overcoming the immune defect induced by deficient TLR4 signaling by combining chemotherapy with alternate TLR4 agonists Abbreviations (HNSCC): Head and neck squamous cell carcinomas; (TLR):...
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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc
Ngày tải lên :
20/06/2014, 04:20
... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...
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báo cáo hóa học:" Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" doc
Ngày tải lên :
20/06/2014, 04:20
... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... methods for genotyping (e.g direct sequencing, pyrosequencing or TaqMan-genotyping) were not considered Figure TLR4 immunohistochemistry in head and neck squamous cell carcinomas (A) Strong (score ... well as overcoming the immune defect induced by deficient TLR4 signaling by combining chemotherapy with alternate TLR4 agonists Abbreviations (HNSCC): Head and neck squamous cell carcinomas; (TLR):...
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báo cáo khoa học: "Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma" pps
Ngày tải lên :
11/08/2014, 00:23
... ataxia-telangiectasia-mutated (ATM) improved radiosensitivity in rodent head and neck cancer models [14-16] In addition, superior imaging in head and neck cancers resulted from the use of superparamagnetic ... Harrison PR: Profiling early head and neck cancer Nat Rev Cancer 2005, 5:127-135 Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment Mayo Clin Proc 2008, ... recurrent/metastatic head and neck cancer Ann Oncol 21(Suppl 7):vii252-vii261 Berrino F, Gatta G: Variation in survival of patients with head and neck cancer in Europe by the site of origin of the tumours...
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Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx
Ngày tải lên :
14/08/2014, 07:21
... which included 17 genes with p53 binding sites in cluster A and 26 genes with NF-κB binding sites in cluster B In cluster A genes with p53 binding sites, putative models containing three and four ... signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Int J Cancer 2002, 99:538-548 Yu M, Yeh J, Van Waes C: Protein kinase ... dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in...
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Regenerative Medicine Reconstruction of Tracheal and Pharyngeal Mucosal Defects in Head and Neck Surgery
Ngày tải lên :
25/10/2013, 08:20
... against infection and invading connective tissue There are still very few studies applying the methods of tissue engineering to produce tracheal replacements and to examine these in vitro and in ... this technique and bearing in mind the contraindications, more than 90% of the children can nowadays be extubated without problems In spite of the progress, in children undergoing single-step surgical ... intubation over several days as an intratracheal splinting An external splinting by metallic microplates in the surgical tracheal reconstruction was described first time by Zalzal and Deutch in...
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Guidance on Cancer Services - Improving Outcomes in Head and Neck Cancers pot
Ngày tải lên :
22/03/2014, 16:21
... clinics at Cancer Centres (see Topic 2, Structure of services and Topic 3, Initial investigation and diagnosis) Designated head and neck cancer clinicians and clinicians in ENT, maxillofacial and ... from head and neck cancers, are discussed in Improving Outcomes in Haematological Cancers.4 There are marked regional variations in the incidence of head and neck cancers, with rates ranging from ... groups and opportunistic screening 44 45 46 47 22 Hobbs C, Birchall M Human papillomavirus infection in the etiology of laryngeal carcinoma Current Opinion in Otolaryngology and Head and Neck Surgery...
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báo cáo hóa học:" Research Article Automatic Speech Recognition Systems for the Evaluation of Voice and Speech Disorders in Head and Neck Cancer" pdf
Ngày tải lên :
21/06/2014, 20:20
... Scottish Intercollegiate Guidelines Network (SIGN), Diagnosis and management of head and neck cancer A national clinical guideline, Edinburgh (Scotland): Scottish Intercollegiate Guidelines Network ... research and clinical purpose in order to determine the global functional outcome of speech and voice after the treatment of head and neck cancer It allows quantifying the intelligibility also in severely ... a low intelligibility and hence a low recognition rate and vice versa The agreement between WR and the mean scores of the perceptual ratings is very high in both patient groups and is in the...
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Báo cáo khoa học: " Stereotactic radiosurgery may contribute to overall survival for patients with recurrent head and neck carcinoma" pptx
Ngày tải lên :
09/08/2014, 09:20
... chemotherapy in head and neck cancer? Ann Oncol 2004, 15:7-11 De Crevoisier R, Bourhis J, Eschwege F: Modified fractionated radiotherapy in head and neck squamous cell carcinoma (HNSCC) & reirradiation in ... feasible, safe, and well-tolerated for patients with local recurrence in head and neck carcinoma Conflict of interests statement The authors declare that they have no competing interests Page ... nasopharyngeal carcinoma Head Neck 2002, 24:748-753 12 Low JS, Chua ET, Gao F, Wee JT: Stereotactic radiosurgery plus intracavitary irradiation in the salvage of nasopharyngeal carcinoma Head Neck 2006,...
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Báo cáo khoa học: "F-FDG PET/CT-based gross tumor volume definition for radiotherapy in head and neck Cancer: a correlation study between suitable uptake value threshold and tumor parameters" pdf
Ngày tải lên :
09/08/2014, 09:20
... volume delineation in head- and- neck cancer using CT and PET/CT fusion Int J Radiat Oncol Biol Phys 2006, 65:726-732 Black QC, Grills IS, Kestin LL, Wong CY, Wong JW, Martinez AA: Defining a radiotherapy ... Cummings B, Dawson L, Keller A, Kim J, Ringash J, Yu E, Hendler A, Waldron J: Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images of head and neck cancers Int ... practicable Schinagl et al compared five methods for determining the BTV using coregistered CT and FDG-PET in HNC patients [26], including visual GTV, 40% and 50% of SUVmax, an absolute SUV of 2.5, and...
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Báo cáo khoa học: "Early clinical experience with volumetric modulated arc therapy in head and neck cancer patients" ppsx
Ngày tải lên :
09/08/2014, 09:20
... modulated radiathion therapy in head and neck cancers: an update Head and Neck 2007, 29:387-400 Popovtzer A, Eisbruch A: Advances in radiation therapy of head and neck cancer Expert Rev Anticancer ... cohort, indicating that the aim of the study is to report about early experiences in head and neck with RapidArc, not focussing on specific outcome or toxicity in single subgroups It includes ... Hypopharynx Larynx Nasal Cavity and Paranasal Sinuses Other 16 10 Histology Squamous cell carcinoma Differentiated carcinoma Undifferentiated carcinoma Adenoidocistic carcinoma Estesioneuroblastoma...
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Báo cáo khoa học: "Dysphagia in head and neck cancer patients following intensity modulated radiotherapy (IMRT)" pptx
Ngày tải lên :
09/08/2014, 09:20
... swallowing dysfunction after curative radiotherapy in head and neck cancer Radiotherapy and Oncology 2009, 90:189-195 Joke W, Kim De R, Duprez F, et al: Acute Normal Tissue Reactions in Head- and- Neck ... KSC, Gokhan O, Wade LT: Toxicity profile of intensity-modulated radiation therapy for head and neck carcinoma and potential role of amifostine Seminars in oncology 2003, 30:101-108 26 Denis F, Garaud ... Definitive Radiotherapy for Locally Advanced Head- and- Neck Cancer International Journal of Radiation Oncology*Biology*Physics 2009, 73:410-415 Cooper J, Fleming ID, editors, HD: Head and Neck...
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Báo cáo khoa học: "Effect of neoadjuvant chemoradiation and postoperative radiotherapy on expression of heat shock protein 70 (HSP70) in head and neck vessels" potx
Ngày tải lên :
09/08/2014, 09:20
... head and neck: interdisciplinary collaboration between head and neck surgeons in 305 cases Ann Plast Surg 1996, 36:37-43 Amarante J, Reis J, Costa-Ferreira A, Malheiro E, Silva A: Head and neck ... 2) and patients treated with neoadjuvant chemoradiation (40 Gy and cisplatin or carboplatin and paclitaxel, group3) Intima of the veins (A, * p < 0.05 vs group1 and group 2), media of the veins ... and patients treated with neoadjuvant chemoradiation (40 Gy and cisplatin or carboplatin and paclitaxel, group3) Intima of the veins (A, *; + p < 0.05 vs group1 and group 2), media of the veins...
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Báo cáo khoa học: "FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma" pps
Ngày tải lên :
09/08/2014, 09:22
... patients with primary head and neck carcinoma were selected for radiotherapy after discussion in multidisciplinary conference and obtaining informed consent following the rules of our institution Patients ... delineation using PET in head and neck cancers: threshold contouring and lesion volumes Med Phys 2006, 33:4280-4288 Black QC, Grills IS, Kestin LL, Wong CO, Wong JW, Martinez AA, Yan D: Defining ... lung and also head and neck tumors [10,26,27] Conclusion The present study shows that FDG-PET/CT images for primary head and neck carcinoma had a potential impact on both tumor staging and treatment...
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Báo cáo khoa học: " IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients" pps
Ngày tải lên :
09/08/2014, 10:20
... Urba S, Lin A, Schipper MJ, Wolf GT: Recurrences near base of skull after IMRT for head- and- neck cancer: implications for target delineation in high neck and for parotid gland sparing Int J Radiat ... failure in patients receiving definitive and postoperative IMRT for head- and- neck cancer Int J Radiat Oncol Biol Phys 2003, 55:312-321 Puri DR, Chou W, Lee N: Intensity-modulated radiation therapy in ... D, Dawson K, Dinardo L, Reiter E: Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head- and- neck squamous cell carcinomas: II clinical results Int J Radiat Oncol...
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Báo cáo khoa học: " The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications" pptx
Ngày tải lên :
09/08/2014, 10:20
... Her-2, Her-3, and Her-4) These receptors are composed of an extra-cellular ligand-binding domain, a hydrophobic transmembrane segment, and an intracellular tyrosine kinase domain Binding to EGFR ... regarding overall survival [29] Tyrosine kinase inhibitors (TKI) and RT In preclinical studies, when gefitinib was combined to RT, strikingly greater than additive effects were observed in vivo ... abnormalities, from hyperplasia to invasive carcinoma, through dysplasia and in situ carcinoma [16] Prognostic value of EGFR expression Most preclinical and clinical studies demonstrated a lower...
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Báo cáo khoa học: " Postoperative IMRT in head and neck cancer" pdf
Ngày tải lên :
09/08/2014, 10:21
... regularly in our joint clinics at the Department of Head and Neck Surgery or Head, Neck and Maxillofacial Surgery Further follow up visits were scheduled every – months in the first years, – monthly in ... has been defined by contouring the anatomic region of the initial primary and nodal GTV, considering the preoperative diagnostics and the clinical and histological findings The PTV1 includes the ... postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial Int J Radiat Oncol Biol Phys...
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báo cáo khoa học:" Early postoperative bone scintigraphy in the evaluation of microvascular bone grafts in head and neck reconstruction" ppt
Ngày tải lên :
11/08/2014, 23:22
... clinical monitoring (92% and 75% respectively) When comparing retrospectively the three monitoring schemes, i.e clinical monitoring alone, bone scans alone and clinical and bone scan monitoring together, ... For bone scintigraphy, 370 MBq 99m-Tc-oxidronate was administered intravenously Static planar scintigramms of 300 seconds were obtained starting to hours after injection in the anterior and both ... ischemia of the skin pedicle and poor scintigraphic findings (score 1), whereas two patients had revision surgery because of poor scintigraphic findings only (score 0) Thrombosis was found in all patients...
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Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf
Ngày tải lên :
18/06/2014, 19:20
... predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area Journal of Translational Medicine 2011 9:31 ... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1497-1503 Adelstein DJ, Li Y, Adams ... objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma Clin Cancer Res 2007,...
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