most common paraneoplastic syndrome in small cell lung cancer
Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... following scoring, as previously described [14]:0 = negative or faint staining in <10% of tumor cells;1 = weak staining in >10% of cancer cells; 2 = moderatestaining; 3 = strong staining. A ... domain. Clin Transl Oncol 2010, 12:75-80.9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors.Oncogene ... ofdetecting EGFR mutations in lung cancer patients.Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non -small- cell lung cancer (NSCLC) cell lines...
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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
... DNA in blood circulationmay act as a risk marker of lung cancer in Taiwan. Cancer 2003,97:1558-1563.11. Klein F, Amin Kotb WF, Petersen I: Incidence of human papilloma virus in lung cancer. Lung ... in lung tumor cells but not in the adjacentnoninvolved lung tissue [9]. HPV 16/18 have beendetected in t he blood of women with cervical infectionsuggesting that HPV 16/18 can infect the lung ... varia-tions. In the United States, HPVs DNA is found in about 20-25% of lung cancers [8]. The most common strains found are HPV 16 and HPV 18, the same strainsthat are commonly found in cervical cancer. ...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... being exploited in cancer, attempting to modulate their expression, rein-troducing microRNAs lost in cancer, or inhibiting onco-genic microRNAs by using anti-micro oligonucleotides[38]. In ... Al-Saad S, Al-Shibli K, et al: Inverse prognostic impact ofangiogenic marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6649-57.24. ... lymphocyte infiltration in non -small cell lung cancer. Clin Cancer Res 2008, 14:5220-7.30. Andersen S, Eilertsen M, Donnem T, et al: Diverging prognostic impacts ofhypoxic markers according to...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer ... expression in non -small cell lung cancer Is correlated with survival. Clin Cancer Res. 2001; 7(7): 1850-5. 93. Cappuzzo F, Gregorc V, Rossi E, et al. Gefitinib in pretreated non -small- cell lung cancer ... ifosfamide in patients with advanced non -small- cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non -Small Cell Lung Cancer Study Group. J Clin Oncol....
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... AccessPathological complete response induced byfirst-line chemotherapy with single agentdocetaxel in a patient with advanced non small cell lung cancer Ferdinando Riccardi1*, Giuseppe Di Lorenzo1, ... Scagliarini1, Florinda Scognamiglio1, Marilena Di Napoli1, Giacomo Carteni’1AbstractBackground: Defining the optimal treatment for patients with inoperable non small cell lung cancer ... discourage to continue treatment.Introduction In non -small cell lung cancer (NSCLC), mediastinallymphnode involvement comprises a wide spectrum ofseverity. In fact, while 9% of patients with...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non -small- cell lung cancer. J Clin Oncol 1999, 17:2692-2699.3. Komaki ... radiochemotherapy with vinorelbine plus cisplatin or carboplatin in patients with locally advanced non -small- cell lung cancer (NSCLC) and an increased risk of treatment complications: Preliminary results. ... chemotherapy and IMRT [21].More clinical evidence on using IMRT in treating lung cancer is needed.We started using IMRT to treat lung cancer in 2005,and we evaluated clinical and dosimetric factors...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... indicated in these patients, though prospectiveclinical studies are needed.Keywords: Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer BackgroundNon -small cell lung ... from NSCLC to any organ(s),including brain, bone, liver,orlungwereincludedinthis study. Only patients with biopsy-proven NSCLCwere included. Those with prior curative-intent treat-ment of metastatic ... controlrates of 60-90% have been reported for metastatictumors involving spine, lung, and liver [16-20]. In this study, patients with initial stage IV NSCLCtreated with aggressive local therapy...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... Inon -small cell lung cancer. Radiother Oncol 2007, 85:429-434.39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat-eral primary lung cancers: the Indiana university experience.Int ... using tumour based image guided posi-tion verification and correction [31]. In addition, small delineation uncertainties will exist. Thus, a minimum of 3mm ITV to PTV margin is required in ... motion into account.However, similar to the reasoning given for the ITV to PTVmargin, a minimum margin of 3 mm should be used forthe incorporation of the other uncertainties.Organs at risk definitionDose...
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... Jeremic B:Report from the international atomic energy agency (IAEA)consultants' meeting on elective nodal irradiation in lung cancer: non -small cell lung cancer (NSCLC). Int J Radiat OncolBiol ... irradiation be omittd in Stage III non -small cell lung cancer? An analysis of recur-rences in a phase II study of induction chemotherapy andinvolved-field radiotherapy. Int J Radiat Oncol Biol ... MK,Macapinlac H, Komaki R, Cox JD: Intrathoracic patterns of fail-ure for non -small- cell lung cancer with position-emissiontomography/computed tomography defined target delinea-tion. Int J Radiat...
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Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx
... suggesting long-lastinglearning experiences in clinical trials. As the need forimmediate monitoring was described by Schaake-Koninget al. [9] from a quality control study in the EORTC lung cancer ... least 1 cm margin aroundthe clinical target volume (CTV); and interfraction interval of 6 hours or longer. Dose constraintswere defined in regards to the spinal cord and the lung. The QA assessment ... at the beginning of thistrial.Dose constraints were defined in regard to the dose to thespinal cord and the lung. The dose to the spinal cord waskept at ≤ 36 Gy. A posterior spinal shield...
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... purposes)BackgroundWorldwide and in Europe lung cancer is the most com-mon cause of cancer related-death with an increasing inci-dence each year. The majority of patients has Non -Small Cell Lung Cancer (NSCLC) ... versussequential thoracic radiotherapy in combination with mito-mycin, vindesine, and cisplatin in unresectable stage III non- small- cell lung cancer. J Clin Oncol 1999, 17:2692-2699.19. Martel ... GD, Bartelink H: Feasibility of escalatingdaily doses of cisplatin in combination with accelerated radi-otherapy in non -small cell lung cancer. Eur J Cancer 1996,32A:1314-1319.7. Uitterhoeve...
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Báo cáo y học: "Clinical significance in the number of involved lymph nodes in patients that underwent surgery for pathological stage III-N2 non-small cell lung cancer" pot
... cisplatinplus irinotecan versus carboplatin plus paclitaxel, cisplatin plusgemcitabine, and cisplatin plus vinorelbine for advanced non -small- cell lung cancer: Four-Arm Cooperative Study in Japan. ... Miyaoka E: The Japanese Joint Committee of Lung Cancer Registry. Prognosis of 6644 resected non -small cell lung cancers in Japan: a Japanese lung cancer registry study. Lung Cancer 2005,50:227-34.11. ... R,Postmus PE, Rusch V, Sobin L: International Association for the Study of Lung Cancer International Staging Committee; Participating Institutions.The IASLC Lung Cancer Staging Project: proposals...
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Báo cáo y học: "RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers" doc
... newcases of lung cancer are diagnosed each year [1]. About85% of lung cancer are non -small cell lung cancer (NSCLC), including adenocarcinoma, squamous cell, and large cell carcinoma [2], and ... Clinical Bioinformatics 2011, 1:6http://www.jclinbioinformatics.com/content/1/1/6Page 6 of 6 REVIE W Open AccessRNA interference against polo-like kinase-1 in advanced non -small cell lung cancersEri ... trials of RNAi therapies against cancers areongoing. In this article, we discuss the most recent findings concerning the administration of siRNA against polo-like kinase-1 (PLK-1) to liver metastatic...
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Báo cáo y học: "proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database" docx
... staining compares the relative intensity of staining ofonecoreofaTMAtothatofacontrolcoreonthesame slide. A score of 1 indicates faint staining, 2 indi-cates medium intensity staining, and 3 indicates ... entered into the database. Patientswith non -small cell lung cancer comprise the majorityof cases annotated within the database. Other cancerscontained in the database include small cell lung cancer, mesothelioma, ... the histological features of thetumor: small cell and non -small cell lung cancer. NSCLC is the more common of the two sub-types of lung cancer, constituting 85% of cases [5,6]. Further-more,...
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Báo cáo y học: "Current role of surgery in small cell lung carcinoma" pot
... actually included in the com-bined small cell lung carcinomas according to WHO morerecent classification [11,13]. Thus it seems more logical tooffer surgery in mixed or combined small cell tumors.3. ... Norstein J: Small cell lung cancer in Norway Shouldmore patients have been offered surgical therapy? Eur j Cardi-othorac Surg 2004, 26:782-786.18. Leo F, Pastorino U: Surgery in small cell lung ... Aam-dal S, Norwegian Lung Cancer Study Group: Cisplatin and etopos-side regimenis superior to cyclophosphamide, epirubicin andvincristine regimen in small cell lung cancer: results from arandomized...
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